한방 치료로 호전된 만성 설염 치험 1례

김태준,곽병문,이유정,김희택,kim, Tae-Jun,Kwak, Byeong-mun,Lee, You-Jung,Kim, Hee-Taek 대한한방안이비인후피부과학회 2021 한방안이비인후피부과학회지 Vol.34 No.3

Objectives : The purpose of this study is to report the effectiveness of Korean medical treatments on chronic glossitis using Yanggyeok-sangagam based on tutakbeop(透托法), and Ikgibohyeol-tanggagam based on botakbeop(補托法) and bobeop(補法). Methods : We treated a 83-year-old female patient who had glossitis by Korean medicine and acupuncture treatment. These treatments were performed from 2020.8.4. to 2021.3.4. We have confirmed the improvement of white plaque like a pseudomembranous pattern lesion and pain. We recorded images that include change of symptoms. Results : After the treatments were done, the scores of numeric rating scale(NRS), oral assessment guide(OAG) and oral health impact profile-14(OHIP-14) were decreased. The NRS score was decreased from 7 to 1. The OAG score was decreased from 20 to 9. The OHIP-14 score was decreased from 34 to 5. Conclusions : According to the result, Korean medical treatments such as Korean medicine and acupuncture treatment, followed by the cure rules- tutakbeop(透托法), botakbeop(補托法) and bobeop(補法) can be effective for the treatment of chronic glossitis.

구기자 복합물 약침액이 간기능 개선에 미치는 영향

김용민,황동석,곽병문,김이화,Kim, Yong-Min,Hwang, Dong-Suk,Kwak, Byeong-Mun,Kim, Ee-Hwa 경락경혈학회 2019 대한침구의학회지 Vol.36 No.4

Objectives : This study investigated the hepatoprotective effect of herbal mixture including Lycii fructus (HML) in thioacetamide (TAA)-induced hepatotoxicity in mice. Methods : To confirm the liver protective effect, induced by TAA for 3 days injection at 100 mg/kg mice, HML were treated for 8 weeks at 300 mg/kg/day, 1000 mg/kg/day. Positive control was treated silymarin 50 mg/kg/day after TAA injection. The changes of mortality rate, clinical signs, organ weight, relative liver, blood chemistry and histopathological findings were analyzed after experiment. Results : Body weight gain was observed in all groups, but TAA treated group at 4th week and all treated groups decreased weight compared to the untreated group. As a result of organ weight measurement, organ weight gain due to hepatic injury was observed statistically significantly in TAA-treated group and TAA+Silymarin treated group, and the herbal mixture-treated group showed a tendency to decrease compared to the TAA treated group. Blood biochemistry showed that total cholesterol and very low density lipoprotein cholesterol decreased statistically in TAA+low-dose and high dose herbal mixture treated group compared to the TAA-treated group. Histopathological examination showed that liver abnormalities were not observed in untreated group, liver fibrosis was observed in liver injury with TAA treated and herbal mixture treated group. And, TAA+high dose herbal mixture group showed relaxation tendency on liver calcification compared to the TAA treated group. Conclusions : According to the above results, HML provided hepatoprotective effects on the hepatic injury by reduction of inflammatory responses.

DFSS를 이용한 플런징 조인트 축력 영향 인자 연구

김기헌(Kihun Kim),곽병문(Byungmoon Kwak),백설(Seol Back) 대한기계학회 2018 대한기계학회 춘추학술대회 Vol.2018 No.12

등속조인트 축력 저감을 위한 설계 변수 인자 분석과 반응 표면 모델을 이용한 축력 저감 연구

김진식(Jinsik Kim),곽병문(Byungmoon Kwak),백설(Seol Back) 한국자동차공학회 2015 한국자동차공학회 학술대회 및 전시회 Vol.2015 No.11

Constant Velocity Joints(CVJ) are important part in automotive driveline components. Constant velocity joint transfer engine power to the chassis. Therefore, Noise, Vibration and Harshness performance and efficiency of Constant velocity joint are very important items. CVJ is composed of various parts that roller, ball, housing, trunnion, cage and so on. These parts contacted each other and the friction inside the joint generates an axial force according to the kinematics. It is generated noise and vibration problems. In this study, CVJ"s parts are modeling by using multibody dynamics. We are selected the design parameters effect on Generated Axial Force(GAF) and carry out the sensitivity analysis for GAF. Finally, minimize to the GAF though optimization method.

회전효과를 고려한 이족 로봇의 정밀 원형 경로 보행

임승철(Seungchul Lim),곽병문(Byungmoon Kwak),임주영(Jooyoung Lim),손영익(Youngik Son) 한국소음진동공학회 2014 한국소음진동공학회 논문집 Vol.24 No.4

When biped robots make turns, the ability to walk stably and precisely along any circular path is crucial. In this context, inverse kinematics solutions are found for accurate gait realization, and new zero moment point(ZMP) equations are derived with respect to the cyclindrical coordinate system to facilitate generation of stable walking patterns. Then, appropriate steady and transitional walking patterns are both proposed in form of time functons. Subsequently, walking patterns for a path but of different speeds are generated using the functions and associated formulas, and preliminarily checked for stability based on the ZMP equations. Upon comparison of those cases, one can see how and when robots may fall down during circular walking. Finally, those patterns are put to test on the sample robot by ADAMS® along with the inverse kinematics solutions and a new balance control scheme compensating for insufficient stability particulary during the initial transition period. Test results show that the robot can walk along the circular path as predicted at a resonably high speed despite the distributed mass and ground contact effects, validating effectiveness of the suggested approach.

자외선 차단제품에서 블루라이트 차단 효과에 영향을 주는 인자에 관한 연구

박수진 ( Soo Jin Park ),곽병문 ( Byeong Mun Kwak ),이미기 ( Mi Gi Lee ),빈범호 ( Bum Ho Bin ) 대한화장품학회 2020 대한화장품학회지 Vol.46 No.4

블루라이트는 380 ~ 450 nm 사이의 파장에 존재하는 파란색 계열의 빛으로 활성산소를 유발하여 노화를 불러일으키는 것으로 보고되었으며, 이에 따라 블루라이트 차단 효과에 대한 관심이 높아지고 있다. 본 연구에서는 자외선 차단제품에서 오일의 극성도, 제형의 점도, 유화제의 종류, 유화입자, 무기자외선 차단제 등이 블루라이트 차단 효과에 미치는 영향에 대해 조사해 보았다. 그 결과 오일의 극성도가 유기자외선차단제의 극성과 유사해질수록 블루라이트 차단율이 높아지는 것으로 확인되었으며, 제형의 점도가 증가할수록 높은 블루라이트 차단율을 나타냈다. 유화제의 종류 및 유화 입자는 블루라이트 차단 효과에 미치는 영향이 미비하였고, 무기자외선 차단제 함유 여부가 블루라이트 차단율에 큰 영향을 주는 인자 중 하나로 나타났다. 이러한 결과들은 블루라이트 차단 효율을 효과적으로 높일 수 있으며, 앞으로 블루라이트 차단 제품 개발 및 제형 연구에 활용될 수 있을 것이다. Blue light is a blue-based light existing at a wavelength between 380 and 450 nm, and it has been reported that it induces active oxygen and causes aging, and accordingly, interest in the blue light blocking effect is increasing. In this study, the effects of the polarity of oil, viscosity of the formulation, type of emulsifier, emulsified particles, and inorganic UV blocking agents on the blue light blocking effect in UV blocking products were investigated. As a result, it was confirmed that the blue light blocking rate increased as the polarity of the oil became similar to that of the organic UV blocker, and the higher the viscosity of the formulation, the higher the blue light blocking rate. The types of emulsifiers and emulsified particles had little effect on the blue light blocking effect, and the presence of inorganic UV blocking agents was found to be one of the factors that greatly influenced the blue light blocking rate. These results can effectively increase the efficiency of blocking blue light, and may be used in the development of blue light blocking products and formulation research in the future.

LuGre 마찰 모델을 이용한 트라이포드 타입 등속조인트 플런징력 해석 상관성 개선 연구

김진식(Jinsik Kim),곽병문(Byungmoon Kwak),백설(Serl Baik),박천일(Chunil Park) 한국자동차공학회 2016 한국자동차공학회 학술대회 및 전시회 Vol.2016 No.11

The Constant Velocity Joint(CVJ) is an important automotive part in the driveline system. There are various types of CVJs. CVJ consists of several parts and these work to 3-dimensions as they rotate and transmit torque to the tire and wheel. In these processes, CVJ"s parts generate friction force, dynamic force and vibration. These characteristic are very important about CVJ performance. So, many engineers have studied for a long time in variety of ways. In this paper, we developed an ADAMS-based CAE tool for automated model generation and standardized dynamic simulation of almost all kind of type CVJ for automotive driveline applications. We specifically study the tripod types of CVJ for plunging force. Plunging force is generally generated mainly when the vehicle is in idle stop. Plunging force is not correlated between test and simulation using coulomb friction model. So, we introduced the LuGre friction model and applied the tripod type CVJ of simulation model.

광석-제련철-슬래그의 암석기재학 및 지화학 특성에 기초한 제철유적 산지추정

조재국(Jaeguk Jo),김서진(Seojin Kim),곽병문(Byeongmoon Kwak),신동복(Dongbok Shin),염경훈(Kyeonghoon Yeom),유병용(Byeongyong Yu),임헌경(Heonkyung Im) 대한지질학회 2020 대한지질학회 학술대회 Vol.2020 No.10

경상지역 제철유적 산지추정을 위한 암석기재학 및 지화학 연구

조재국(Jaeguk Jo),김서진(Seojin Kim),곽병문(Byeongmoon Kwak),신동복(Dongbok Shin),염경훈(Kyeonghoon Yeom),유병용(Byeongyong Yu),임진아(Jinah Im),임헌경(Heonkyung Im) 대한지질학회 2021 대한지질학회 학술대회 Vol.2021 No.10

경상지역에 분포하는 주요 제철유적 7개소와 인근 철광상 8개소에서 얻은 철광석, 철슬래그, 철유물을 대상으로 암석기재학 및 지화학특성에 근거한 산지추정 연구를 수행하였다. 주요 철광산에서 획득한 자철석은 주로 열수기원으로 스카른광물과 함께 산출되지만 대금광산에서는 장석류와 함께 화성기원의 산점상을 보인다. 또한, 물금 및 함안광산 자철석은 황화물과 함께 산출되는 특징을 보인다. 자철석 주원소 특성에 근거한 광상유형 도시결과 대부분 스카른광상에 속하며 화성기원의 대금광산을 제외하면 모두 열수기원으로 나타난다. 밀양사촌유적 철광석은 석영과 함께 자철석이 발달하여 열수기원의 스카른 광상이었음을 암시한다. 부산 지사동 슬래그에서는 재결정화된 구리화합물이 검출되어 다른 유적시료와 구별된다. 울산지역 달천 철광석 및 토철 내 자철석에서 확인된 비소의 평균 함량은 각각 0.15 wt.%와 0.14 wt.%로서 나머지 철광산(av. 0.13 wt.%)보다 다소 높은 경향을 보인다. 철광석 내 비소는 자철석과 교호하는 규산염광물에서 확인되며 이들은 제련과정에서 파생된 제철유적 슬래그 내 비소 농집에 기여한 것으로 보인다. 제철유적 전암시료 주원소 변화 곡선은 시료간 구별된 차이를 보이지만 향후 미량원소 변화곡선 및 납-스트론튬 동위원소와 연계한 종합검토가 요구된다.

쌀겨오일의 안티폴루션 화장품 소재로써의 응용

강해란,정소영,허효진,차병선,이소민,여혜림,유경완,곽준수,곽병문,이미기,빈범호,Kang, Hae-Ran,Jung, So Young,Heo, Hyojin,Cha, Byungsun,Brito, Sofia,Lee, So Min,Yeo, Hye Lim,Yoo, Kyung Wan,Kwak, Jun Soo,Kwak, Byeong-Mun,Lee, Mi-Gi,Bin, B 대한화장품학회 2021 대한화장품학회지 Vol.47 No.3

미세먼지와 초미세먼지는 일반적으로 사람 머리카락의 두께에 비하여 각각 1/6 ~ 1/7, 1/20 ~ 1/30 정도로 매우 작은 부유성 먼지를 뜻하며, 다양한 종류의 중금속 이온이 내포되어 있다. 호흡뿐 아니라 피부의 모공 틈새를 통해서 유입된 미세먼지는 체내 조직과 피부 건강에 문제를 유발할 수 있기 때문에 유입을 막거나 깨끗이 씻어내어 제거해야 한다. 본 연구를 통해 Oryza sativa (Rice) bran oil (OSBO, 쌀겨오일)을 이용하면 중금속 이온을 흡착하여 제거할 수 있을 것이라는 가능성을 확인하였다. 또한, 세포독성 실험을 통해 세포 생존율이 곡물 유래 성분과 비교했을 때에도 월등히 높아 외부 자극원에 대한 세포 보호 효과를 기대할 수 있다. COL1A1 mRNA의 발현량이 높아짐을 확인하였고, 이에 따라 미세먼지 속 중금속 이온에 의해 손실된 수분으로 유발될 수 있는 주름을 완화할 수 있을 것으로 사료된다. 이러한 실험 결과를 바탕으로 최종적으로 중금속 제거를 위한 워시-오프 제형의 OSBO 함유 화장품을 제시하고자 하였다. Particulate matter and ultra-particle matters generally refer to very small floating dust, such as 1/6 to 1/7 and 1/20 to 1/30, respectively, compared to the thickness of human hair, and contain various types of heavy metal ions. In addition to breathing, particle matters (PM) that flows in through the gaps in the pores of the skin can induce health problems in the body's tissues and skin, so it must be removed by blocking the inflow or by washing. Through this study, we confirmed the possibility that heavy metal ions can be adsorbed and removed by using Oryza sativa (Rice) bran oil (OSBO). In addition, the cell viability is much higher than that of grain-derived components through cytotoxicity experiments, and the cytoprotective effect of an external stimulus source can be expected. It was confirmed that the expression amount of COL1A1 mRNA increased, and accordingly, it was believed that wrinkles that might be caused by moisture lost by heavy metal ions in fine dust could be alleviated. Based on the results of these experiments, we tried to present a cosmetics containing OSBO, which is a wash-off formulation, in order to finally remove heavy metals.