다문화가정아동의 복문 발달 특성

공미경,김성수 국제다문화의사소통학회 2012 국제다문화의사소통학회 학술대회 Vol.2012 No.11

The purpose of this study was to examine the characteristics of development in complex sentence of the young children in multicultural families. 27 children in multicultural families and 27 normal ones aged 2, 3 and 4 participated. The rate of complex and three subtypes of sentences (compound, embedded, and compound-complex type of sentence) were analyzed through 120 spontaneous language samples in free plays. The results of this study were as follows. First, there was not a significant difference in the rate of complex sentence use between two groups, but not for the aged 2 groups. Second, the rate of compound sentences use was most high for the both groups, and followed by the embedded sentences and the compound-complex ones. In both groups, the compound and the compound- complex sentences appeared at the same age 3. But embedded sentence types were distinctive characteristics between two groups. Conclusively, it was suggested that although the children of multicultural families had lower abilities in complex sentence production than those of normal families in the 2 aged period, they could catch up gradually the normal families’ children one or two years later.

과민성방광의 진단 및 치료

공미경 대한산부인과학회 2019 연수강좌 Vol.61 No.-

하부요로 기능장애

공미경 대한산부인과학회 2023 대한산부인과학회 학술대회 Vol.109 No.-

스팸성 자질과 URL 자질의 공동 학습을 이용한 최대 엔트로피 기반 스팸메일 필터 시스템

공미경 ( Mi Gyoung Gong ),이경순 ( Kyung Soon Lee ) 한국정보처리학회 2008 정보처리학회논문지B Vol.15 No.1

본 논문에서는 스팸메일에 나타나는 스팸성 자질과 URL 자질의 공동 학습을 이용한 최대엔트로피모델 기반 스팸 필터 시스템을 제안한다.스팸성 자질은 스패머들이 스팸메일에 인위적으로 넣는 강조 패턴이나 필터 시스템을 통과하기 위해 비정상적으로 변형시킨 단어들을 말한다.스팸성 자질 외에 반복적으로 나타나는 URL과 비정상적인 URL도 자질로 사용하였다. 메일에 나타난 정상적인 URL과 필터 시스템을 피하기 위해 변형된 비정상적인 URL들이 스팸 메일을 걸러내는데 도움을 줄 수 있기 때문이다. 또한 스팸성 자질과 URL자질을 이용한 공동 학습을 하였다. 공동 학습은 학습 과정에서 두 자질을 독립적으로 이용한 비지도 학습 방법으로 정답을 모르는 문서를 이용할 수 있다는 장점을 갖는다. 실험을 통해 스팸성 자질과 URL을 이용함으로써 스팸 필터 시스템의 성능을 향상시킬 수 있음을 확인하였으며 두 자질 집합을 이용한 공동 학습이 필요한 학습 문서의 수를 감소시키면서, 정확도는 일괄 학습 정확도에 근접한다는 것을 확인하였다. This paper presents a spam filter system using co-training with spamminess features and URL features based on the maximum entropy model. Spamminess features are the emphasizing patterns or abnormal patterns in spam messages used by spammers to express their intention and to avoid being filtered by the spam filter system. Since spammers use URLs to give the details and make a change to the URL format not to be filtered by the black list, normal and abnormal URLs can be key features to detect the spam messages.Co-training with spamminess features and URL features uses two different features which are independent each other in training. The filter system can learn information from them independently. Experiment results on TREC spam test collection shows that the proposed approach achieves 9.1% improvement and 6.9% improvement in accuracy compared to the base system and bogo filter system, respectively.The result analysis shows that the proposed spamminess features and URL features are helpful. And an experiment result of the co-training shows that two feature sets are useful since the number of training documents are reduced while the accuracy is closed to the batch learning.

스팸성 자질과 URL 자질을 이용한 최대엔트로피모델 기반 스팸메일 필터 시스템

공미경(Mi-Gyoung Gong),이경순(Kyung-Soon Lee) 한국정보과학회 언어공학연구회 2006 한국정보과학회 언어공학연구회 학술발표 논문집 Vol.2006 No.10

본 논문에서는 스팸메일에 나타나는 스팸성 자질과 URL자질을 이용한 최대엔트로피모델 기반스팸 필터 시스템을 제안한다. 스팸성 자질은 스패머들이 스팸메일에 인위적으로 넣는 강조 패턴이나 필터 시스템을 통과하기 위해 비정상적으로 변형시킨 단어들을 말한다. 스팸성 자질 외에 반복적으로 나타나는 URL과 비정상적인 URL도 자질로 사용하였다. 메일 수신자에게 추가적인 정보 제공을 목적으로 하이퍼링크로 연결시키거나 메일에 직접 길러내는데 도움을 줄 수 있기 때문이다. 또한 스팸성 자질과 URL을 각각 적용한 두 분류기를 통합하였다. 분류기의 통합은 각 분류기에 이용된 자질을 독립적으로 사용할 수 있다는 장점을 가지고 있다. 실험 결과를 통해 스팸성 자질과 URL을 이용함으로써 스팸 필터 시스템의 성능을 향상시킬 수 있음을 확인할 수 있었다.

다문화가정아동의 복문 발달 특성

공미경(Mi Kyoung Kong),김성수(Sung Soo Kim) 한국언어치료학회 2012 言語治療硏究 Vol.21 No.4

The purpose of this study was to examine the developmental characteristics in complex sentences of young children from multicultural families. Twenty-seven children from multicultural families and 27 children from homogenous families aged 2, 3 and 4 participated in this study. The rate of complex and three subtypes of sentences (compound, embedded, and compound-complex type of sentence) were analyzed through 120 spontaneous language samples collected during free play.The results of this study were as follows. First, there was no significant difference in the rate of complex sentence use between the two groups, with the exception of the two-year-old groups. Second, the rate of compound sentence use was highest for both groups. This was followed by embedded sentences and compound-complex sentences. In both groups, the compound and the compoundcomplex sentences appeared at the same age 3. However, embedded sentence types showed distinctive characteristics between the two groups.It was suggested that although children from multicultural families had lower abilities in complex sentence production than the children from homogenous families in their twos, they could gradually catch up one or two years later.

Synergistic Antitumor Effects of Combined Treatment with HSP90 Inhibitor and PI3K/mTOR Dual Inhibitor in Cisplatin-Resistant Human Bladder Cancer Cells

김형준,공미경,윤철용,강재구,윤미진,조남훈,라선영,최영득 연세대학교의과대학 2020 Yonsei medical journal Vol.61 No.7

Purpose: The current study aimed to investigate the synergistic antitumor effect of combined treatment with 17-DMAG (HSP90 inhibitor) and NVP-BEZ235 (PI3K/mTOR dual inhibitor) on cisplatin-resistant human bladder cancer cells. Materials and Methods: Human bladder cancer cells exhibiting cisplatin resistance (T24R2) were exposed to escalating doses of 17-DMAG (2.5–20 nM) with or without NVP-BEZ236 (0.5–4 μM) in combination with cisplatin. Antitumor effects were assessed by CCK-8 analysis. Based on the dose-response study, synergistic interactions between the two regimens were evaluated using clonogenic assay and combination index values. Flow cytometry and Western blot were conducted to analyze mechanisms of synergism. Results: Dose- and time-dependent antitumor effects for 17-DMAG were observed in both cisplatin-sensitive (T24) and cisplatin-resistant cells (T24R2). The antitumor effect of NVP-BEZ235, however, was found to be self-limiting. The combination of 17-DMAG and NVP-BEZ235 in a 1:200 fixed ratio showed a significant antitumor effect in cisplatin-resistant bladder cancer cells over a wide dose range, and clonogenic assay showed compatible results with synergy tests. Three-dimensional analysis revealed strong synergy between the two drugs with a synergy volume of 201.84 μM/mL2%. The combination therapy resulted in G1-phase cell cycle arrest and caspase-dependent apoptosis confirmed by the Western blot. Conclusion: HSP90 inhibitor monotherapy and in combination with the PI3K/mTOR survival pathway inhibitor NVP-BEZ235 shows a synergistic antitumor effect in cisplatin-resistant bladder cancers, eliciting cell cycle arrest at the G1 phase and induction of caspase-dependent apoptotic pathway.

Manchester Operation: An Effective Treatment for Uterine Prolapse Caused by True Cervical Elongation

박윤진,공미경,이진애,김은화,배상욱 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.11

Purpose: Descent of the uterus is a major etiology of uterine prolapse. However, true cervical elongation can cause uterine prolapsewithout uterine descent. The aim of study was to investigate the clinical outcomes of Manchester operation in patients withuterine prolapse caused by “true cervical elongation,” compared with vaginal hysterectomy (VH). Materials and Methods: Medical records of patients who underwent Manchester operation or VH from 2006 to 2015 were reviewed. True cervical elongation was defined on the basis of C point of the Pelvic Organ Prolapse Quantification (POP-Q) system≥0 and D point ≤-4, as well as estimated cervical length of ≥5 cm. The primary outcome was recurrence of pelvic organ prolapse(POP) evaluated by POP-Q system. The outcomes of two groups were compared after propensity score matching, for age, parity,and preoperative POP-Q stage. Results: During the study period, 23 patients underwent Manchester operation and 374 patients underwent VH. The recurrencerate of POP (p=0.317) and complication rate were not statistically significant different between the two study groups. Manchesteroperation exhibited shorter operation time than VH (p=0.033). In subgroup analysis (POP-Q stage III), body mass index [odds ratio(OR)=1.74; 95% confidence interval (CI), 1.08–2.81] and not having concurrent anterior colporrhaphy (OR for concurrent anteriorcolporrhaphy, 0.06; 95% CI, 0.01–0.75) were identified as significant risk factors for recurrence of POP. Conclusion: The Manchester operation technique seems to be an effective and safe alternative procedure for the treatment ofuterine prolapse caused by true cervical elongation, compared with VH.

소음노출 후 흰쥐 내이 와우유모세포의 형태적 변형

이석기,강훈희,공미경,이광선,정종우 대한이비인후과학회 2005 대한이비인후과학회지 두경부외과학 Vol.48 No.8

Background and Objectives:Mechanism of inner ear hair cell distortion after noise exposure has been well described. The present study was designed to determine the response to the auditory system of a genetically well-defined laboratory mouse in preparation for examining the effect of noise on mice with specific genetic mutations. So it is important to recognize the relationship between noise exposure duration and hair cell morphological changes. We try to reveal the hearing loss and inner ear hair cell morphological changes after applying the noise protocol. Subjects and Method:The mice were BALB/c hybrids and aged 8 weeks. Six mice served as non-noise-exposed controls and 8 mice were exposed for 3 hours per day to white band noise with a center frequency from 0.2 kHz to 70 kHz and a sound pressure level of 120 dB. And we divided the noise exposure group into 3 subgroups(1 day, 3 day, 5 day noise exposure group). We checked the photographs of FITC phalloidin stain and scanning electron microscopy of cochlea after noise exposure. Results:The hearing level of mice decreased after noise exposure. We could see the stereocilia damage in cochlea after FITC phalloidin stain in cochlea and sterocilia loss was more severe in basal turn. In scanning electron microscopy, morphological changes of stereocilia were observed to be more severe in the cochlear basal turn than other area. Significant hair cell loss in the cochlear basal turn could be calculated using cochleocytogram. Conclusion: 120dB broad white band noise can damage the hair cell of cochlea in mice. These changes were especially severe in the cochlearbasal turn. Noise exposure duration is the other important factor in damaging cochlear hair cells. Therefore, we can guess that harmful noise level and noise exposure duration are the main risk factors that injure the inner ear hair cell.

일반연제 발표 : 논문 ; 산과학 : 임상편 ; 임신성고혈압(Pregnancy Induced Hypertension) 임부의 제왕절개술전(帝王切開術前) 치료와 모체측 예후

양미혜,이예경,공미경,유한기,우복희,강신명 대한산부인과학회 1984 대한산부인과학회 학술대회 Vol.54 No.-