중고령자의 삶의 만족도 결정요인에 대한 연구

고혜진,정해식 한국노인복지학회 2022 노인복지연구 Vol.77 No.1

This study investigates the cause of the low life satisfaction of Korean middle-aged and older adults and to verify the effect of intimate relationship and public social security that can reduce the risk of decreasing life satisfaction late in life caused by the deterioration of health, retirement, decrease in income, and loss of a spouse. We analyze the determinants of life satisfaction through a fixed-effect model and survival analysis using longitudinal data from the 1st to 7th wave of the Korean Longitudinal Study of Ageing. Consequently, housing stability and intimate social relationships significantly increase the life satisfaction of middle-aged and older people. With these factors, public social security can prevent life satisfaction from being too low. To increase life satisfaction late in life, it is necessary to secure stable income by expanding public social security, removing the inconvenience in daily life, and providing a place to accelerate social activities. 이 연구는 우리나라 중고령자가 보이는 낮은 삶의 만족도의 원인을 찾고, 사회적 관계와공공 사회보장이 삶의 만족도 저하를 방지할 수 있는지 확인하는 것을 목적으로 한다. 이때삶의 만족도를 변화시키는 요인으로 중고령자가 경험하는 건강 악화, 경제활동 상태 변화, 소득감소, 배우자 상실과 같은 부정적 생애 경험에 주목하고자 하였다. 생애 경험들의 영향을 고려하기 위해 고령화연구패널의 1차부터 7차까지 종단자료를 활용하여 고정효과 모형및 생존분석을 통해 유배우 중고령자의 삶의 만족도 결정요인을 분석하였다. 분석 결과, 주거 안정과 원활한 사회적 관계는 중고령자의 삶의 만족도를 유의미하게 높이는 것으로 나타난다. 이들 요인과 함께 공공 사회보장은 삶의 만족도가 과도하게 낮아지는 것을 방지한다. 이러한 결과를 바탕으로, 중고령자의 삶의 만족도 저하를 막으려면 공공사회보장을 확충하여 안정적인 소득 기반을 갖추도록 하고, 건강 악화에 따른 일상생활 불편을 해소하는 것이 필요하다는 정책 함의를 도출하였다. 또한 사회적 관계를 유지할 수 있는 장을 마련하는 것도 필요하다. 이 연구는 중고령자의 삶의 만족도 결정요인을 종단적으로 분석하여 중고령자의 삶의 만족도 저하를 초래하는 생애 변화의 영향을 통제한 상태에서 이들의 삶의 만족을 제고할 수 있는 요인을 분석하였다는 데 의의가 있다.

헤도닉 모델에 의한 생태공원의 인접 아파트 가격 영향 분석 - 청주 원흥이공원과 인접 아파트를 대상으로 -

고혜진,윤기범,심용주,황희연,Ko, Hye-Jin,Yun, Ki-Bum,Shim, Young-Ju,Hwang, Hee-Yun 한국주거학회 2011 한국주거학회 논문집 Vol.22 No.5

The purpose of this research is to demonstrate the necessity of conserving and maintaining eco-parks by estimating their economic value. Wonheung-ee Park in Sannam 3 District of Cheongju City was chosen as the subject and a quantitative estimation was conducted. The quantitative analysis utilized the hedonic price model that estimates the value of non-market goods. The summarized results of this study are follows. The subject park influenced the prices of its neighboring apartments. The most important factor was the distance between the park and the subject apartment. When the distance was longer than 400m, the impact was greatest. The quantitative assessment also showed that apartment prices and the distance between an apartment and the park had a negative relationship. When the distance increased by 1%, apartment prices decreased by 0.430%. This means that within a certain distance, the closer an apartment is to the park, the higher is the price. Demonstrating the economic value of eco-parks, this study also supports the importance of preserving eco-areas. It generally shows that when we develop a city, we should refrain destroying the ecosystem.

라이프스타일에 따른 실버타운 제공서비스 선호요인 연구 - 청주지역 예비노인층을 대상으로 -

고혜진,황희연,Ko, Hye-Jin,Hwang, Hee-Yun 한국주거학회 2008 한국주거학회 논문집 Vol.19 No.6

The development of modern medicine and economic growth has caused the elderly population to increase rapidly in Korea and the country is becoming an aging society. As the population of elderly has increased the interest in silver towns has also increased. the elderly population is more affluent in the past and more willing to spend their money on themselves. This led to the need of supplying silver towns where they can have comfortable retirement. The research conducted for this study was to understand the silver town market by finding the preference of silver town service according to their life style. The target of this survey was the pre-elderly in the Cheongju area and several analysis techniques like factor analysis, crowding analysis, and conjoint analysis were used to understand the life style of the preelderly and preference factors of silver town services.

정상 범위 내의 혈청 Gamma-glutamyltransferase와 심혈관 질환의 위험요인과의 관련성: Framingham Risk Score를 중심으로

고혜진,최창수,윤창호,이덕희,이성국 대한비만학회 2013 The Korean journal of obesity Vol.22 No.1

Background: We investigated the association between serum GGT level with risk factors of cardiovascular diseases and the Framingham risk score (FRS). Methods: A Total of 712 subjects (men 160, women 552) were enrolled, excluding 296 subjects either having any of hepatic diseases, taking medications that could affect liver function, having abnormal liver function, or drinking alcohol excessively. We classified the subjects into terciles according to the serum GGT levels. We analyzed the differences and trends of clinical characteristics between the three groups, and the correlation between serum GGT level and FRS. Results: As the serum GGT level increased, there was an increases in blood pressure, body mass index, total cholesterol, triglyceride, fasting glucose, and FRS in women,whereas only triglyceride and FRS increased in men (P <0.05). Multivariate regression analysis was performed after adjusting for BMI and waist circumferences with FRS as the dependent variable. The results showed positive association between GGT and FRS in both men and women, which were statistically significant (β = 0.632, P = 0.011 in men;β = 0.769, P = 0.004 in women). Conclusion: There was a positive association between serum GGT level within normal range and Framingham risk scores. Serum GGT level may be considered as a useful biomarker to estimate the risks of cardiovascular diseases. 연구배경: 최근 연구에서 gamma-glutamyltransferase (GGT)는 고혈압, 당뇨병, 대사증후군 등과 관련성이 있는 것으로 알려졌으나 심혈관계 위험인자에 대한 관련성의 연구는부족한 실정이다. 심혈관 질환의 위험도를 평가하는 전통적인지침인 Framingham risk score (FRS)와 정상범위 내의 GGT 와의 관련성을 알아보고자 하였다. 방법: 간질환이 있거나, 간기능에 영향을 줄 수 있는 약물을복용하거나, 간기능 이상소견이 있거나, 과음하는 사람을 제외하고 혈청 GGT가 정상인 712명(남자 160명, 여자 552명)을최종대상으로 하여 체지수, 혈압, 혈액검사결과를 분석하였다. 연령, 수축기 혈압, 총콜레스테롤, 고밀도지단백콜레스테롤 등을 바탕으로 FRS를 계산하였다. 남녀 각각 GGT를 삼분위수로 나누어 분석하고 GGT와 FRS와의 상관관계를 분석을 위해다중회귀분석을 실시하였다. 결과: GGT에 따라 삼분위수로 나누었을 때, 남성에서 GGT 가 높아질수록 중성지방과 FRS 점수가 유의하게 증가하였고,여성에서는 체질량지수, 허리둘레, 혈압, 총콜레스테롤, 중성지방, 공복혈당이 유의하게 증가하였고 고밀도콜레스테롤은 유의하게 감소하였다. 심혈관 위험인자를 보정한 다중회귀분석결과 GGT는 FRS와 유의한 양의 상관관계로 나타났다. (남성β = 0.632, P = 0.011, 여성 β = 0.769, P = 0.004)결론: 정상범위 내에서 GGT는 남녀 모두에서 FRS와 유의한 양의 상관관계를 보이므로 심혈관 질환의 위험도를 평가하는데 하나의 지표로 고려해 볼 수 있다.

북한 친구에게

고혜진 한국국어교육학회 2000 세계가 한동네 Vol.2000 No.-

붕장어(Conger myriaster)의 피부로부터 평활근 수축작용을 지닌 신경성 펩타이드의 정제

고혜진,박남규 한국수산과학회 2012 한국수산과학회지 Vol.45 No.4

A novel neuropeptide was isolated from the skin of the conger eel Conger myriaster using hagfish Eptatretus burgeriintestine as a bioassay system. The sequence of the purified peptide was analyzed using automated amino acid sequencing and MALDI-TOF mass spectrophotometry. The molecular ion peak in the MALDI-TOF mass spectrum of the peptide was at m/z 962.89 (M+H)+. The sequence of the peptide was determined to be L-P-M-L-E-T-Q-M, and was tentatively named comyrin. To investigate the complete primary structure of comyrin, comyrin-OH and comyrin-NH2 were synthesized and the chemical and pharmacological properties of the synthetic peptides were compared with those of the native peptide. However, the elution time of synthetic peptides did not match that of the native peptide on the reverse-phase HPLC chromatogram. In addition, the synthetic peptides did not cause contractile activity in the intestinal smooth muscle of the hagfish. Based on these results, one possible reason for this disagreement may be the presence of a D-amino acid in comyrin.

별 불가사리(Asterina pectinifera) 조직별 초산추출물의 생리활성 탐색

고혜진,박남규,조미정,김군도 한국수산과학회 2014 한국수산과학회지 Vol.47 No.2

The present study was performed to examine the contraction and relaxation responses of the smooth muscles, and search for antimicrobial and antioxidant activities in the tissues, of the starfish Asterina pectinifera . Frozen samples were extracted with distilled water containing 1% acetic acid. Extracts from all tissues showed potent antimicrobial activity against Escherichia coli D31. Relatively high levels of antimicrobial activity were also detected in the body extracts. Liver, tube feet, and body extracts caused contraction responses in the dorsal retractor muscles (DRM) of the starfish. In contrast, all tissues examined exhibited contractile activity in the esophagus of squid Todarodes pacificus . In addition, liver and gonad extracts caused contraction responses upon application to the intestine of the puffer fish Takifugu pardalis . Relaxation effects on the DRM of starfish were identified in most of the extracts, while no relaxant activity was detected in body extracts. Extracts from all tissues examined also exhibited antioxi- dant activities. The results of this study suggest that starfish are a potential source of novel bioactive compounds.

복지국가의 재정적 지속가능성 측정

고혜진 한국사회복지학회 2016 한국사회복지학회 학술대회 자료집 Vol.2016 No.4

가물치(Channa argus)로부터 평활근 수축활성 펩타이드의 정제

고혜진,박남규 한국수산과학회 2012 한국수산과학회지 Vol.45 No.2

A novel neuropeptide was isolated from the skin of the snakehead Channa argus using the dorsal retractor muscle (DRM) of a starfish Asterina pectinifera as a bioassay system. The amino acid sequence of the purified peptide was analyzed using automated sequencing and MALDI-TOF mass spectrophotometry. The primary structure of the purified peptide was determined to be Pro-Ala-Leu-Ala-Leu. To investigate the complete primary structure of this peptide, Pro-Ala-Leu-Ala-Leu-OH and Pro-Ala-Leu-Ala-Leu-NH2 were synthesized. The chemical and pharmacological properties of the synthetic peptides were compared with those of the native peptide. Both the native peptide and synthetic Pro-Ala-Leu-Ala-Leu-OH had identical behaviors on the reverse-phase and cation-exchange HPLC chromatograms. Synthetic Pro-Ala-Leu-Ala-Leu-OH showed contractile activity on the DRM, and the threshold concentration of this peptide was approximately 10-8 M. The maximal contractile effect (Emax) of this peptide was 294±45.4% at 10-5 M.

한국의 사회복지지출에 대한 해석의 차이는 어디에서 비롯하는가? - 97년 경제위기 이후 한국의 사회복지지출 수준에 관한 연구를 중심으로 -

고혜진 한국사회복지학회 2011 한국사회복지학회 학술대회 자료집 Vol.2011 No.4