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우리나라 만성 C형간염 환자에서 페그인터페론과 리바비린의 병합치료에 대한 효과
강명주 ( Myoung Joo Kang ),정은욱 ( Eun Uk Jung ),박상원 ( Sang Won Park ),최바울 ( Pa Ul Choi ),김지현 ( Ji Hyun Kim ),박성재 ( Sung Jae Park ),박은택 ( Eun Taek Park ),이연재 ( Youn Jae Lee ),이상혁 ( Sang Hyuk Lee ),설상영 ( Sa 대한간학회 2008 Clinical and Molecular Hepatology(대한간학회지) Vol.14 No.3
한양천 ( Yang Chun Han ),강명주 ( Myoung Joo Kang ),박정하 ( Jeong Ha Park ),이원석 ( Won Sik Lee ),손창학 ( Chang Hak Sohn ),김찬환 ( Chan Hwan Kim ),주영돈 ( Young Don Joo ) 대한내과학회 2006 대한내과학회지 Vol.71 No.6
위장관에 발생하는 T세포 악성림프종은 발생 빈도가 낮고, 특히 식도에 발생하는 원발성 T세포 악성림프종은 극히 드문 것으로 보고되고 있다. 저자들은 60세 남자로 수 주 간의 연하곤란을 주소로 내원하여 상부위장관 내시경 검사 및 방사선학적 검사상 T세포 악성림프종으로 진단받은 후 복합항암요법을 통해 성공적으로 치료된 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Gastrointestinal tract (GIT) lymphomas usually originate from B-lymphocytes but rarely from T-lymphocytes. The stomach is the most common site for extranodal GIT lymphoma but the esophagus is a rare site. In addition, a primary esophageal T-cell lymphoma is an uncommon disorder. We encountered a case of a primary esophageal T-cell lymphoma in a 11 60-year-old man, who had swallowing difficulties and multiple ulcers in the upper and lower esophageal mucosa on gastroscopy. Immunohistochemical staining for the biopsy material from the multiple esophageal ulcers tested positive for LCA and CD45RO (pan T-cell marker) and negative for cytokeratin and CD20 reactivity, respectively. No other abnormal lesions were observed on a computed tomography scan of the neck, chest, abdomen and pelvis. After six cycles of combination chemotherapy with cyclophosphamide, adriamycin, vincristin, prednisolone, etoposide and gemcitabine, the multiple esophageal ulcers had completely disappeared suggesting a complete clinical response. We report this case with a review of the relevant literature(Korean J Med 71:694-698. 2006)
크론병과 장결핵의 감별에 있어 특징적인 대장내시경 소견
제인수 ( In Soo Je ),이상혁 ( Sang Hyuk Lee ),정은욱 ( Eun Uk Jung ),강명주 ( Myoung Joo Kang ),박상원 ( Sang Won Park ),최바울 ( Pa Ul Choi ),김지현 ( Ji Hyun Kim ),박성재 ( Sung Jae Park ),지삼룡 ( Sam Ryong Jee ),박은택 ( Eun T 대한장연구학회 2007 Intestinal Research Vol.5 No.2
Background/Aims: The incidence of Crohn``s disease (CD) is on the increase in Korea. The differentiation of Crohn``s disease from intestinal tuberculosis (IT) is difficult. The aim of this study is to determine the characteristics of colonoscopic findings and factors that differentiate CD from IT. Methods: A total of 136 patients who were diagnosed with CD or IT at the Busan Paik Hospital from January 1995 to May 2005 were included in this study. We analyzed endoscopic findings, clinical characteristics and histological findings of 75 patients with CD and 61 patients with IT retrospectively. Results: For patients with IT, 18 (58.1%) of the patients had circular ulcers. For patients with CD, 27 (42.1%) of the patients had transverse ulcers, 18 (28.1%) of the patients had longitudinal ulcer, and 19 (29.6%) of the patients had both types of ulcers. The involvement of the ileocecal valve was noted in 18 (58.0%) of the patients with CD and in 37 (57.8%) of the patients with IT. The involvement of the rectum or anus was noted in 24 (51.5%) of the patients with CD and one (3.2%) patient with IT. Conclusions: According to previous studies, the presence of an ulcer was important to differentiate CD from IT. However, the presence of an ulcer was not a significant differentiating factor in our study. On colonoscopic findings, involved segments, an aphthous ulcer, cobblestone appearance, involvement of the rectum or anus and mucosal bridge should be observed carefully. (Intest Res 2007;5:158-164)