고요산혈증의 위험인자 : 아산시 지역 주민을 대상으로

김용배,장원기,황보영,김화성,안규동,이병국,이용진,이종은,이준숙,이찬구,이한정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Objective : Serum uric acid has now been identified as a marker for a number of metabolic and hemodynamic abnormalities. The aim of this study is to evaluate risk factors which influence hyperuricemia in the citizens of Asan. Method : The study design was cross-sectional and research subjects were 1086 citizens of Asan. General characteristics, cigarette smoking, alcohol consumption, and past history were obtained by interview using a structural questionnaire. Also, we measured height, weight and blood pressure, and serum uric acid of the subjects. Results : The mean serum uric acid level was 5.27 ㎎/㎗ in men and 4.01 ㎎/㎗, in women, In the multiple logistic regression analysis, statically significant risk factors of hyperuhcemia were gender, body mass index, blood lead concentration, and serum creatinine. Conclusion : Our results suggest that gender, body mass index, blood lead concentration, and serum creatinine might be the most important risk factors of hyperurcemia. Education program as well as routine check-up for serum uric acid was highly recommended for the effective prevention of hyperuricemia.

기상변화에 의한 기관지천식 발생빈도 분석에 지리정보체계의 유용성

김용배,함정오 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

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醫藥品 製造設計 및 操作分析의 最適化에 關한 硏究 : 錠劑製造의 最適化

金瑢培 圓光大學校大學院 1978 學位論叢 Vol.1 No.-

Tablet product design problem was structured as constrained optimization problem and subsequently solved by multiple regression analysis and Lagrangian method of optimization. Aluminium flufenamate was the drug chosen and microcrystalline cellulose and starch were the binder and disintegrant, respectively. The effect of the binder and disintegrant concentration on tablet hardness, friability, volume, in vitro release rate, and urinary excretion rate of drug in human subjects was recorded. Since a reasonably rapid release rate of drug is generally an important objective in the design of solid dosage form, optimization of this parameter was employed in studying the applicability of constrained optimization to a pharmaceutical product design problem. In addition to finding optimal solutions to constrained pharmaceutical problems, the application of sensitivity analysis studies to such problems was also illustrated. It would appear that prediction of the in vivo t'_(50)% response from a knowledge of the in vitro t_(50)% response can be made fairly accurately for the tablet system used in this study.

청량음료의 미생물 오염에 대하여

김용배,이병국,유건희,조남선 한국미생물학회 1973 미생물학회지 Vol.11 No.3

The authors have investigated about the microbial contamination of goods which is a criterion of hygienic control. Conducting on investigation, a special attention has been paid on the rate of microbial contamination in the goods, especially in manufacturing process of the softdrink. The authors also made an experiment on total microbes which is the criterion of contamination in each step of the process and in raw materials together with materials to be used for subdividing. Results obtained were as follows : 1) The orgin of microbial contamination was found in bottle cap and in tap water, that is, there appeared 9 colony per ml in bottle cap and 31-74 colony per ml in tap water, respectively. 2) It was found that microbial contamination are 4 colony per ml in average through year. However, it appeared 1 colony per ml in winter and 8 colony per ml in summer. 3) Coliform groups are not detected in goods through a year. 4) There was no variation in number of total microbes after ion exchange resin passage in purification process of tap water. 5) The number of microbes in goods are decreased when the raw materials are treated in high temperature short time (HTST) sterilization.

65세 이상의 노령층에서 고지혈증의 위험요인

김용배,장원기,황보영,김화성,안규동,이병국,이용진,김세훈,김승수,김승훈,김영록,김웅빈,이성수 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

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정신교육교재문제와 강좌운영 : 통일연수소의 사례를 중심으로

김용배,최봉기 한국국민윤리학회 1982 倫理硏究 Vol.13 No.1

Cholesteryl S-Alkoxybenzene Thiocarbonate의 합성과 액정 성질에 관한 연구(1)

金容培 건국대학교 1988 學術誌 Vol.32 No.2

The Cholesteryl S-Ethoxybenzene Thiocarbonate and the Cholesteryl S-Propoxybenzene Thiocarbonate were synthesised and their liquid crystal phase transition temperature were determined by optical method. Those compounds exhibit a cholesteric mesophase which are "Polygonal texture" and "Schlieren texture."

人間關係管理의 技術問題

金瑢培 東亞大學校 1963 東亞論叢 Vol.1 No.-

The human actions which act in the organization as a functional being is primarily limited by the organization of management. However, it does always follow the rules of a formal organization as human being invoives various and complicated elements. Therefore, organization may be classified into two sides formal organization and informal organization. The former is an organization brought by the rules of organization and latter is brought by human elements. The management of human relations sets its key point on an in formal organizations. The human relations management usually tries to understand social relations and to find the reasonable methods through a survey of individual personality such as motive for activity, desire and attitude between a formal and informal grups The research on the management of human relations was began by Prof. E. Mayo of Harvard University. He took Hawthorne Research as the method and investigated the Western Eiectric Company. He finally concluded that the efficiency of labour mainly depends on labour's affection. Therefore, the efficiency in production can be improved by rather improvement of human relations between manager and labour or among labours than the change in rest or work. The question may be raised when Mayo's conclusions to an organization. What and how human relations can be improved in the organization for the Question, following points and methods may be recommended : 1. The method for survey of labour a. moral survey b. counselling 2. Improvement of communication 3. The improvement of work-shop a. leader-ship training b. delegation of authority 4. The method of paticipation for management a. suggestion system b. multiple management c. group approach management In conclusion, the key point of human management is that a man is livng being. Therefore a man must be treated and accomodated by the circumstances and functions of the organization.

SIMS: Circuit Interconnect Modeling Environment for VLSI Design

김용배,백준호,김춘경,차건업,정원영 대한전자공학회 1994 대한전자공학회 학술대회 Vol.1994 No.7

연취급 근로자들의 혈중 ZPP 농도 선별기준에 따른 정확도의 변화

김용배,안현철,황보영,리갑수,이성수,안규동,이병국,Kim, Yong-Bae,Ahn, Hyun-Cheol,HwangBo, Young,Lee, Gap-Soo,Lee, Sung-Soo,Ahn, Kyu-Dong,Lee, Byung-Kook 대한예방의학회 1997 예방의학회지 Vol.30 No.4

Measurement of blood lead (PbB) and blood zinc protoporphyrin (ZPP) are most common biological indices to identify the individual at risk for excess or the health sequences by lead exposure. Because PbB is known most important and reliable index of lead exposure, PbB is often regarded as a gold standard to detect lead exposure. But in Korea PbB is a secondary test item of detailed health check-up with positive finding of screening test in most occasion. Our lead standard requires all lead workers to take annual heath-check twice a year for investigation of their health effect due to lead exposure. Blood ZPP is one of most important index to detect high lead absorption in lead workers as a screening test. Measurement of blood ZPP is known ,well to correlate with PbB in steady state of exposure in most lead workers and is often used as a primary screening test to detect high lead absorption of lead workers with the advantage of simplicity, easiness, portability and low cost. The current cut-off criteria of blood ZPP for further detailed health check-up is $100{\mu}g/d\ell$ which is supposed to match the level of $40{\mu}g/d\ell$ of PbB according to our standard. Authors tried to investigate the validity of current criteria of cut-off level $(100{\mu}g/d\ell)$ of blood ZPP and possible another better cut-off level of it to detect the lead workers whose PbB level over $40{\mu}g/d\ell$. The subjects in our study were 212 male workers in three small scale storage battery industries. Blood ZPP, PbB and hemoglobin (Hb) were selected as the indices of lead exposure. The results were as follows. 1. The mean of blood ZPP, PbB and Hb in lead workers were $79.5{\pm}46.7{\mu}g/d\ell,\;38.7{\pm}15.1{\mu}g/d\ell,\;and\;14.8{\pm}1.2g/d\ell$, respectively. There were significant differences in blood ZPP, PbB and Hb by industry (P<0.01). 2. The percents of lead workers whose blood ZPP were above $100{\mu}g/d\ell$ in the group of work duration below 1, 1-4, 5-9 and above 10 years were 8.6%, 17.2%, 47.6%, and 50.0%, respectively. The percents of lead workers whose PbB were above $40{\mu}g/d\ell$ in those were 31.4%, 40.4%, 71.4%, and 86.4%, respectively. 3. The percents of lead workers whose PbB were below $40{\mu}g/d\ell$, $40-59{\mu}g/d\ell$ and above $60{\mu}g/d\ell$ were 54.7%, 34.9% and 10.4%, respectively. Those of lead workers whose blood ZPP were below $100{\mu}g/d\ell$, $100-149{\mu}g/d\ell$ and above $150{\mu}g/d\ell$ were 79.2%, 13.7% and 7.1%, respectively. 4. Simple linear regression of PbB on blood ZPP was statistically significant (P<0.01) and as PbB was $40{\mu}g/d\ell$, blood ZPP was $82.1{\mu}g/d\ell$. 5. While the highest sensitivity and specificity of blood ZPP test to detect lead workers with PbB eve. $40{\mu}g/d\ell$ were observed in the cut-off level of $50{\mu}g/d\ell$ and $100{\mu}g/d\ell$ of blood ZPP, respectively, the highest validity (sensitivity+specificity) of blood ZPP to detect lead workers with PbB over $40{\mu}g/d\ell$ was observed in the cut-off level of around $70{\mu}g/d\ell$ of blood ZPP. But even with optimal cut-off level of around $70{\mu}g/d\ell$ of blood ZPP, still 25.0% of false negative and 20.7% false positive lead workers were found. As the result of this study, it was suggested that reconsideration of current blood ZPP cut-off of our lead standard from $100{\mu}g/d\ell$ to somewhat lower level such as around $70{\mu}g/d\ell$ and the inclusion of PbB measurement as a primary screening test for lead workers was highly recommended for the effective prevention of lead workers.