한국인 유전성 유방암 연구 이후 국내 유전성 유방암 진료 패턴의 변화

김성원,강은영,안세현,노우철,노동영,정용식,김이수,최두호,서영진,김구상,이정언,이민혁,남석진,문병인,손병호,양정현,염차경,김성용,박수경,김성원 한국유방암학회 2010 Journal of breast cancer Vol.13 No.4

Purpose: The objective of this study was to evaluate the change in the practice patterns for managing hereditary breast and ovarian cancer (HBOC) among Korean physicians after the Korean Hereditary Breast Cancer (KOHBRA) study. Methods: The first survey was performed from July to August 2007, at the initiation of the KOHBRA study, and the followup survey was conducted from July to December 2009. Members of the Korean Breast Cancer Society were invited to participate in the study by e-mail. The 2009 survey was conducted with a self-administered questionnaire concerning HBOC management and was identical to the previous questionnaire. Results: According to the 2009 survey, most physicians (60.0%) tended to draw a pedigree (48.0% in 2007 survey). The rate of genetic test recommendations for patients at risk for HBOC was higher in the 2009 survey (84.0%) than that in the 2007 survey (64.0%). Physicians tended to select a BRCA genetic testing candidate more appropriately than in the previous survey (42.4% answered right in 2007 survey; 74.4% in 2009 survey). Fifteen of 25 participants (60.0%) provided genetic counseling before their patients underwent a genetic test, which was higher than that (40.0%) in the 2007survey. According to the 2009 survey, half of the genetic counseling was being conducted by KOHBRA study research nurses; whereas most of the genetic counseling was conducted by physicians in 2007. Conclusion: The KOHBRA study has played an important role in the appropriate selection of candidates for genetic testing. However, more effort should be placed on improving the pre-test genetic counseling rate.

프로그래밍 기반 TPACK 교육 프로그램이 예비 교사의 수업 전문성에 미치는 효과

김성원,이영준 한국컴퓨터정보학회 2020 韓國컴퓨터情報學會論文誌 Vol.25 No.7

본 연구에서는 김성원과 이영준(2019)의 프로그래밍 기반 TPACK 교육 프로그램이 예비 교사의 수업전문성에 미치는 효과를 분석하였다. 연구 대상은 40명의 예비 교사이며, 두 집단으로 나누어 처치를진행하였다. 실험 집단(n=20)에게는 프로그래밍 기반 TPACK 교육 프로그램을 처치하고, 통제 집단(n=20)에게는 ICT 도구 기반 TPACK 교육 프로그램을 적용하였다. 예비 교사의 수업 전문성 변화를분석하기 위하여 수업 전문성, 교수 효능감, 테크놀로지 통합 자아효능감을 측정하는 검사 도구를 사용하였다. 연구 결과, 통제 집단과 달리 실험 집단은 수업 전문성과 교수 효능감, 테크놀로지 통합 자아효능감이 유의하게 향상되었다. 사전 검사에서는 실험 집단과 통제 집단이 유의한 차이가 존재하지 않았지만, 사후 검사에서는 실험 집단이 통제 집단보다 수업 전문성이 유의하게 높았다. 이러한 결과를 통하여프로그래밍을 활용한 TPACK 교육이 예비 교사의 수업 전문성 발달에 효과적인 것을 확인할 수 있었다. This study analyzes the effects of programming-based TPACK education programs, designed by Kim and Lee (2019), on the teaching expertise of pre-service teachers. The research subjects were 40 pre-service teachers, divided into an experimental group and a control group. The experimental group underwent the programming-based TPACK education program, and the control group used an ICT-based TPACK education program. A test tool was used to measure not only teaching expertise but also teaching efficacy and self-efficacy beliefs about technology integration. As a result of the study, teaching expertise, teaching efficacy, and self-efficacy beliefs about technology integration improved significantly in the experimental group. The pretest showed no significant difference between the experimental group and the control group, but in the post-test, the experimental group showed significantly higher teaching expertise than the control group. These results showed that the programming-based TPACK education program is effective for developing teaching expertise in pre-service teachers.

프로그래밍 기반 TPACK 교육 프로그램이 예비 교사의 TPACK에 미치는 효과

김성원,이영준 한국컴퓨터교육학회 2020 컴퓨터교육학회 논문지 Vol.23 No.4

This study aims to verify the effectiveness of the programming-based TPACK educational program developed by Kim and Lee (2019) in improving the TPACK of pre-service teachers. The treatment used ICT-based (control) and programming-based TPACK educational programs (first, second, third, and final cycle) developed through design-based research. TPACK test tools were implemented pre and post treatment, and the test results were analyzed using ANCOVA. Therefore, the TPACK of pre-service teachers who implemented the programming-based TPACK educational program was significantly higher compared to the ICT-based TPACK educational program. Furthermore, through this design-based research, the effect of the developed final educational program on the TPACK of pre-service teachers was particularly the most outstanding. Therefore, it can be concluded that the programming-based TPACK education program developed through design-based research is effective in improving the TPACK of pre-service teachers. 본 연구에서는 김성원과 이영준(2019)에서 개발한 프로그래밍 기반 TPACK 교육 프로그램을 검증하는 연구이다. 연구에서 처치는 설계 기반 연구를 통하여 개발한 프로그래밍 기반 TPACK 교육 프로그램(1차, 2차, 3차, 최종)과 ICT 기반 TPACK 교육 프로그램을 사용하였다. 교육 프로그램의 효과를 분석하기 위하여 사전, 사후에 TPACK 검사 도구를 실시하였으며, 검사 결과는 ANCOVA를 통하여 분석하였다. 적용 결과, 프로그래밍 기반 TPACK 교육 프로그램을 적용한 예비 교사의 TPACK은 ICT 기반 TPACK 교육 프로그램보다 유의하게 높았다. 특히 설계 기반 연구를 통하여 최종적으로 개발한 교육 프로그램이 예비 교사의 TPACK 발달에 가장 효과적이었다. 이러한 연구를 통하여 설계 기반 연구를 통하여 예비 교사의 TPACK 향상에 효과적인 프로그래밍 기반 TPACK 교육 프로그램을 개발하였다는 것을 확인하였다.

학술 커뮤니케이션을 위한 인터넷 정보자원의 안정성에 대한 연구 - 국내 문헌정보학 분야를 중심으로 -

김성원 한국문헌정보학회 2019 한국문헌정보학회지 Vol.53 No.3

Rapid development and dissemination of ICT have brought about vast change in people’s lives, including academic research and communication. Considering that the purpose of constructing Internet was to facilitate information exchange among research institutions and to secure stability through distributed preservation of critical information of the countries, increase in utilizing Internet resources for academic research seems to be natural consequences. This study examines the stability of Internet information resources by analyzing the following four factors. First, monitoring whether there is a change in accessibility to information resource as time passes. Second, examining various factors affecting the accessibility. Third, checking if there is a change in the content of information, if still accessible. Lastly verifying if any alternative access path is provided in case of original resource is no longer accessible. 정보통신기술의 발전 및 보급은 학문 연구와 학술 커뮤니케이션을 포함한 우리 생활 전반에 걸쳐 큰 변화를 초래하고 있다. 인터넷 구축의 목적이 연구기관간의 정보교류와 국가의 주요 정보를 분산 보존하여 안정성(stability)을 확보하고자 함에 있었음을 고려할 때, 학문 연구의 과정에서 인터넷 정보자원의 활용이 증가하고 있는 것은 당연한 결과로 볼 수 있다. 본 연구는 학문 연구와 학술 커뮤니케이션 과정에서 인용된 인터넷 정보자원의 안정성을 시간의 경과에 따른 접속가능성(accessibility)의 변화, 접속가능성에 영향을 미치는 제반 요인, 접근이 가능한 경우 내용상의 변화여부, 그리고 접근이 불가능한 경우 대체경로를 통한 구득가능성의 네 가지 관점에서 종합 검증하였다.

개에 있어서 Chloramphenicol 의 뇨 및 담즙중 배설기전에 관한 연구

김성원 한국약제학회 1977 Journal of Pharmaceutical Investigation Vol.7 No.1

A study on the mechanism of biliary and urinary excretion of chloramphenicol has been performed in the dog. 1) Chloramphenicol administered intravenously to dogs with ligated renal pedicle, readily appeared in bile greater than in plasma. 6.9% of a 50㎎/㎏ i. v. dose of chloramphenicol were excreted into bile within 100 minutes. During the same periods of above experiment, the bile/plasma concentration ratios(B/P ratios) were 46 to 87. 2) Chloramphenicol injected into the vein of dog was rapidly excreted into urine. 18% of the administered dose were excreted into urine within 70 minutes. In the same periods of this experiment, Ccm/Ccr ratios were greater than 1.0 in most cases. 3) In experiment of simultaneous measurement of biliary and urinary excretion of chloramphenicol, Ccm/Ccr ratios were less than 1.0 and B/P ratios were 50 to 52. 4) In experiment measured simultaneously biliary and urinary excretion both Ccm/Ccr and C^HCm(hepatic clearance) were significantly declined by probenecid, but not affected by 2, 4-DNP and aminophylline although 2, 4-DNP increased only bile flow and aminophylline both bile and urine volume. 5) Ccm/Ccr and C^HCm were increased in proportion to increment of plasma concentration ranging from 3.3 to 30 ㎎% of chloramphenicol. But when plasma concentration were increased to 70㎎%, Ccm/Ccr were not increased and C_HCm were reduced about 30% in comparison with values obtained at 30㎎% of chloramphenicol. 6) Free/Bound(free to bouid from) ratios ranging from 1.0 to 90.0㎎% of chloramphenicol were 76.2+3.72% (mean±S.E.) Above results suggest that chloramphenicol is excreted into bile by a process of active trasport, that excretion of chloramphenicol into urine was made up with dual process, reabsorption and secretion, and that renal secretion was attained by active trasport process although renal reabsorption process could not understand.

보육교사의 대인관계스트레스와 교사-영유아 상호작용이 어린이집 CCTV 인식에 미치는 영향

김성원,이지영 인문사회 21 2020 인문사회 21 Vol.11 No.1

CCTV perception is recognized as one of the major variables in relation to child abuse of child care teachers. Therefore, this study was performed to examine how interpersonal stress and teacher-child interaction work as predictors of CCTV perception of childcare teachers. The subjects of this study were 177 childcare teachers working in childcare centers in Seoul and Gyeonggi province and collected data were analyzed by SPSS 23.0. The results of this study are as follows. First, interpersonal stress and teacher-child interaction of childcare teachers were negatively correlated with CCTV perception. Second, interpersonal stress had a negative effect on CCTV perception. Third, Teacher-child interaction negatively affected CCTV perception. The results of this study suggest that interpersonal stress and teacher-child interaction should be considered as significant factors in order to positively improve CCTV perception of childcare teachers. 보육교사의 CCTV 인식은 아동학대와 관련된 주요한 변인으로 인식되고 있다. 본 연구의 목적은 보육교사의 대인관계 스트레스와 교사-영유아 상호작용이 어린이집 CCTV 인식에 미치는 영향을 살펴보는 것이다. 연구대상은 서울과 경기도의 어린이집에서 근무하는 보육교사 177명이며 자료는 SPSS 23.0으로 분석하였다. 본 연구의 결과는 다음과 같다. 첫째, 보육교사의 대인관계 스트레스, 교사-영유아 상호작용은 CCTV 인식과 부적 상관관계가 있는 것으로 나타났다. 둘째, 대인관계 스트레스는 CCTV 인식에 부적 영향을 미치며 교사-영유아 상호작용은 CCTV 인식에 부적 영향을 미치는 것으로 나타났다. 본 연구의 결과는 보육교사의 CCTV 인식을 긍정적으로 개선하기 위해서 보육교사의 대인관계 스트레스와 교사-영유아 상호작용을 고려해야 함을 시사한다.

Christian Childcare Teachers’ Perceptions of Child Abuse in Open-Ended Questions

김성원 한국기독교교육정보학회 2019 Journal of Christian education information tech Vol.0 No.36

This study is intended to explore Christian childcare teachers’ perceptions regarding child abuse in childcare centers, and differences of perceptions related to demographic and Christian backgrounds. Two hundred and one Christian childcare teachers participated in this study and seven openended questions were asked of them. They identified reasons for child abuse at childcare centers: lack of professionalism, overwork, a child’s problematic behavior, teacher’s character, job stress, poor working conditions, emotion-control difficulties, and others. Participants suggested the preventive alternatives to child abuse at childcare centers were: improvement of working conditions, teacher education, character education, CCTV, parent education, low ratio between teacher and child, and others. The differences in the responses among demographic groups were explored by a chi-square of independence tests, and the differences were found in the spiritual influence on child abuse and the distinction between biblical discipline and abuse by years and frequency of church attendance. This study is significant in that it reveals that Christian backgrounds affect the Christian teacher’s child abuse perception and provides Christian applications.

CFRP-bar NSM 시스템의 부착거동에 관한 실험적 연구

김성원,김현호,여환준,박성무 대한건축학회지회연합회 2014 대한건축학회연합논문집 Vol.16 No.6

구조물보강에서 전세계적으로 주목받고 있는 NSM시스템은 기존의 콘크리트 구조체에 매립 홈을 형성하고, FRP 보강재를 접착재로 충진하여 일체성확보와 아울러 보강성능을 발현하고자 하는 공법이다. 부착강도예측을 위해 현재까지 전 세계적으로 많은 연구자들이 실험적으로 부착강도모델을 제시하고 있으나 파괴모델에 근거한 제한적 강도모델을 제시하는 경우가 일반적이다. 따라서, 본 연구는 CFRP-bar NSM 시스템의 부착거동에 대한 실험결과를 정량적으로 평가하고, 영향변수별 기여도에 근거하여 부착파괴를 포괄하는 범용적 부착강도모델을 제안하며, 선행연구에 근거하여 제안된 유효부착길이 실험결과를 토대로 종국적으로 최소보강길이에 개념에 대한 유효부착길이의 타당성을 실험적으로 검증하고자 한다. Of the many strengthening systems, NSM(near surface mounted) system with FRP bar has become attractive and popular way of strengthening for the existed RC structures. To effectively apply this method, bond characteristics at the interface need to be fully understood. This paper presents the results of an experimental program to investigate the bond behaviour of CFRP- bar NSM system for strengthening RC beams. The overall experimental program consisted of 16 pull-push tests RC specimens with CFRP-bar NSM system for variables such as strengthening length, sectional aspect ratio of CFRP-bars and grooves, adhesives. The performance of each NSM strengthened beams is presented, discussed, and compared in terms of failure mode, ultimate load, load-slip relationship, and test-to-predicted ratio. Based on the test results, this paper provides researchers and practical engineers a fundamental knowledge and intuition about the bond behaviour of CFRP-bar NSM system.

양로원 노인의 낙상에 대한 두려움

김성원,양윤준,어광수,조흥준,김영식 대한가정의학회 1998 Korean Journal of Family Medicine Vol.19 No.12

담배형 금연보조제의 안전성

김성원 대한가정의학회 2000 Korean Journal of Family Medicine Vol.21 No.7