20게이지와 23게이지 평면부 유리체절제술 후 각막지형도 변화의 비교

박영민,이지은,엄부섭.Young Min Park. MD. Ji Eun Lee. MD. Boo Sup Oum. MD 대한안과학회 2009 대한안과학회지 Vol.50 No.3

Purpose: To compare the changes in corneal topography between 23 gauge (G) pars plana vitrectomy (PPV) and 20 G PPV. Methods: Forty-three eyes of 42 patients who underwent PPV were divided into 2 groups: 20G PPV (Group I, n=18) and 23 G PPV (Group II, n=25). Both groups were followed up over 3 months postoperatively. ORBSCAN II was performed to compare the corneal topographic change of 20 G PPV and 23 G PPV. Results: In a 5 mm zone, significant postoperative change in the mean corneal surface cylinder was found between the 1st day and the 1st month in Group I, while no significant change was found in Group II. Postoperatively, the increase in the mean corneal surface cylinder in Group I was significantly higher than in Group II between the 1st day and the 1st month. Clinically significant astigmatism, induced by surgery, was found only in Group I one week after the operation. In a 3 mm zone, there was no significant change in the mean corneal surface cylinder in both groups postoperatively. The difference in the mean corneal surface cylinder between the 2 groups at the postoperative periods showed no significant change. Surgically induced astigmatism was significantly higher in Group I than in Group II between the 1st day and the 1st month postoperatively. Conclusions: PPV with the 23 G system is a sutureless transconjunctival surgery, which appears to be more effective due to insignificant corneal surface and astigmatic changes in the early postoperative period.

우울증 환자에서 불면과 자살, 세로토닌의 연관성

박영민,강승걸,이헌정,김린,Park, Young-Min,Kang, Seung-Gul,Lee, Heon-Jeong,Kim, Leen 대한수면의학회 2014 수면·정신생리 Vol.21 No.1

Objectives: The aim of current study is to evaluate the relationship between sleep, suicide and serotonin using some scales and loudness dependence of auditory evoked potentials (LDAEP). Methods: Total 65 patients who met the criteria for major depressive disorder were enrolled in current study. The patients were divided into two subgroups according to their insomnia and a history of suicide attempts. The auditory event-related potentials were measured to evaluate LDAEP before beginning antidepressants. Results: The scores of total Beck Depression Inventory (BDI) and BDI item 9 (suicide) were higher in insomnia subgroup than non-insomnia subgroup (respectively, p=0.0033 and p=0.03). However, LDAEP did not differ each other. The subgroup with a history of suicide attempts had a higher score of BDI item 9 than the subgroup without a history of suicide attempts (p=0.00012). There was a tendency for the LDAEP to be higher in the subgroup with a history of suicide attempts ($1.39{\pm}0.94{\mu}V$) than the sub-group without a history of suicide attempts ($1.05{\pm}0.75{\mu}V$), although the difference was not statistically significant (p=0.078). Conclusion: Suicidality was related to insomnia. In addition, there was a tendency for serotonin activity to be lower in the subgroup with a history of suicide attempts. In future, more studies are needed.

피부과 외래환자에서 아토피피부염의 상대 빈도와 임상적 특징 및 검사 소견에 관한 연구

박영민,박홍진,김태윤,김정원 ( Young Min Park,Hong Jin Park,Tae Yoon Kim,Chung Won Kim ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.1

Background : Atopic dermatitis(AD) is a common disease, and population-based studies indicate that the frequency of AD has increased substantially during recent decades. However, there have been few studies on the hospital based relative frequency, and clinical and laborat,ory findings of AD in Korea. Objective : The presenl study was aimed to elucidate the relative frequency of AD on the outpatient base, and to investigate the clinical manifestations and immunological laboratory findings. Methods : Our study was designed by analysing outpatients with AD via physical examination, questionnaires and immunological investigations such as skin prick tests, Multi test CMI, and measurernent of eosinophil counts, total IgE, Derrnatophagoides pteronyssinus-specific IgE and eosinophil cationic protein(ECP). Results : The results were as follows : 1. The relat,ive frequen:y of AD on the hospital base in 1995-1996 was 8.6%. 2. The mean age of onset was 3.36 years. 57.3% of the patients had their onset of eczema by the age of 1 year, 65.5% by 2 years and 83% by 5 years. The most common site at the onset was the face followed by antecubital area, popliteal area, neck, and trunk. 3. The predilection site on physical examination were the face, neck, antecubit,al area, popliteal area and trunk in decreesing order. 4. Concomitant allergic rhinitis, keratoconjunctivitis and asthma were present in 2~3.4%, 14.1%, and 9.5% of patients with AD, respect.ively, whereas pure AD was present in 34.1%. 5. Family history of atopy was observed in 60.5% of AD patient.s. 6. The most frequent ninor fea~ture of AD was xerosis followed by perifollicular accentuation, allergic shiner, cheilitis, imitation allergy, palrnar hyperlinearity and molluscum cantagiosum. 7. Seasonal aggravation was found in 86.8% of patients with AD, especially in summer and winter, The rnost significant aggravating factors were wools followed by sweating, heating, dryness, excessive bat.hing and emotional stress. 8. Abnormal levels of .osinophils, total IgE and ECP were seen in 44.8%, 78.9% and 31.7% Of patients with AD, respec.ively. 9. Cell mediated immunty was decreased in 68.2% of patients with AD. 10. Positive reactivity( at least rnore than one alle~rgen) in the skin prick t,est was noted in 76% of pat,ients with AD and the most popular 8 allergens were D. pteronyssinus, D. farinae, cat fur, M4 mixed threshing dust., dog hair, mugwort pollen, H3 tree pollen and birch pollen. 11. The specific IgE aritibodies to D. pteronyssinus(>+1) were found in 72.3% of AD patients and correlated with the r esults of the skin prick test in 76%. Conclusion : The hospi al-based relative frequency of AD investigated in our study tends to be increased. As the clinica featu~res and laboratory findings of AD might be influenced by genetic, environrnental and psychological factors, the systernic evaluation of patients with AD will be needed (Kor J Dermatol 1997;35(1): 96-106)

공초점주사현미경에 의한 푹스각막이상증의 각막조직소견

박영민,최범석,이종수.Young Min Park. MD. Beom Seok Choi. MD. Jong Soo Lee. MD. PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.9

Purpose: To analyze the morphology and density of corneal tissue in patients with early stage Fuchs’ corneal endothelial dystrophy (FCED) by in vivo confocal microscopy (IVCM). Case summary: Each layer of the cornea in 2 patients with early-stage FCED was examined with IVCM (ConfoScan 4.0, NIDEK, Co. Ltd., albignasego, Italy). Cross-sectioned corneal images of the corneal epithelium, Bowman’s layer, stromal layer, Descemet’s membrane, and endothelium were evaluated. Corneal epithelium, Bowman’s layer, and anterior stroma of both patients showed no abnormalities. Case 1 was diagnosed as Stage 1 FCED, demonstrating typical changes including pleomorphism, polymegathism, and the presence of guttae in the corneal endothelial layer. Case 2 was diagnosed as Stage 2 FCED, showing several hyper-reflective whitish dots in the posterior stroma, hypo-reflective vertical strands in the stroma adjacent to Descemet’s membrane, and pleomorphism, polymegathism, and guttae in the corneal endothelial layer. Conclusions: IVCM is a non-invasive and effective tool to diagnose early-stage FCED.

주요우울증 환자에서 일주기 형태에 따른 양극성 경향, 자살 사고, 청각유발전위와의 관련성 : 예비 연구

박영민,이승환,Park, Young-Min,Lee, Seung-Hwan 대한생물정신의학회 2014 생물정신의학 Vol.21 No.1

Objectives The current study investigated the putative relationship between chronotype and suicidality or bipolarity in patients with major depressive disorder (MDD). Method Nineteen outpatients who met the criteria for MDD according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders-text revision were recruited for the current study. The subjects were divided into two subgroups based on their Basic Language Morningness (BALM) scores (dichotomized according to the median BALM score). The Loudness Dependence of Auditory Evoked Potentials (LDAEP) was evaluated by measuring the auditory event-related potentials before beginning medication with serotonergic agents. In addition, K-Mood Disorder Questionaire (K-MDQ), Beck Scale for Suicidal Ideation (BSS), Beck Hopelessness Scale (BHS), Barratt Impulsiveness Scale (BIS) were applied. Results The K-MDQ, BSS, BHS, BIS score was higher for the eveningness group than for the morningness group. However, the LDAEP, Hamilton Depression Rating Scale, Hamilton Anxiety Scale scores did not differ significantly between them. There were negative correlations between the total BALM score and the total K-MDQ, BSS, and BHS scores (r=-0.64 and p=0.0033, r=-0.61 and p=0.0055, and r=-0.72 and p=0.00056, respectively). Conclusions Depressed patients with eveningness are more vulnerable to the suicidality than those with morningness. Eveningness is also associated with bipolarity.

LCC를 고려한 BOX구조물 뒷채움 재료의 경제성 분석

박영민,김수용,Park, Young-Min,Kim, Soo-Yong 한국건설관리학회 2009 한국건설관리학회 논문집 Vol.10 No.6

The lightweight bubble mixture soil is used for soft ground rear-filling material by applying reduced weight on structure. However, comparing with the general soil, it is not applied in domestic because of initial phase cost of construction. General soil, which has lower initial phase cost is usually used for rear-filling, but the use of overlay method of general soil is reduced as the number of layers increases. Especially box structure placed in soft ground or the overlay method when gap near pier rear-filling can be replaced with temporary alternative method, however, it can't be a solution to gap by generation of extra weight of thickness of overlaying. Therefore, execute LCC analysis of two alternative-the general and the lightweight bubble mixture soils, which are rear-filling material of box structure- and present economical analysis in order to make resonable decision from the economics. As a result, although the lightweight bubble mixture soil takes higher initial phase cost than the general soil, it has been analyzed to procure economical efficiency by having less cost of maintenance.

개량 습윤제의 Streptococcus mutans 및 Candida albicans에 대한 영향

박영민,권혁권,여규영,이은숙,한만덕,정인식 ( Young Min Park,Hyuk Kon Kwon,Kue Young Yeo,Eun Sook Lee,Man Deuk Han,In Sik Chung ) 대한예방치과·구강보건학회 1997 대한구강보건학회지 Vol.21 No.2

액상-환원법으로 초미세 Cu 분말 제조 시 반응 조건의 영향

박영민,진형호,김상렬,박홍채,윤석영,Park Young Min,Jin Hyeong Ho,Kim Sang Ryeol,Park Hong Chae,Yoon Seog Young 한국재료학회 2004 한국재료학회지 Vol.14 No.11

Ultra-fine Copper particles for a conductive paste in electric-electronic field were prepared using wet-reduction process with hydrazine hydrate ($N_{2}H_4{\cdot}H_{2}O$) as a reductor. The effect of reaction conditions such as the amount of dispersion ($Na_{4}O_{7}P_2{\cdot}10H_{2}O$) and reductor ($N_{2}H_4{\cdot}H_{2}O$) on the particle size and shape for the prepared Cu powders was investigated. The quantity of dispersion and reductor varied from 0 to 0.0025 M and from 5 to 40 ml at a reaction temperature of $70^{\circ}C$, respectively. The particle size, shape, and structure for the obtained Cu particles were characterized by means of XRD, SEM, TEM, EDS and TGA. The aggregation of Cu particles was reduced with relatively increasing of the amount of dispersion at fixed other reaction conditions. The smaller Cu particle with size of approximately 300nm was obtained from 0.032 M $CuSO_4$ with adding of 0.0025 M $Na_{4}O7P_2{\cdot}10H_{2}O$ and 40ml $N_{2}H_4{\cdot}H_{2}O$ at a reaction temperature of $70^{\circ}C$.

수면 관련 식이 장애

박영민,Park, Young-Min 대한수면의학회 2011 수면·정신생리 Vol.18 No.1

Sleep-related eating disorder (SRED) is a newly recognized parasomnia that describes a clinical condition of compulsive eating under an altered level of consciousness during sleep. Recently, it is increasingly recognized in clinical practice. The exact etiology of SRED is unclear, but it is assumed that SRED might share features of both sleepwalking and eating disorder. There have been also accumulating reports of SRED related to the administration of various psychotropic drugs, such as zolpidem, triazolam, olanzapine, and combinations of psychotropics. Especially, zolpidem in patients with underlying sleep disorders that cause frequent arousals, may cause or augment sleep related eating behavior. A thorough sleep history is essential to recognition and diagnosis of SRED. The timing, frequency, and description of food ingested during eating episodes should be elicited, and a history of concurrent psychiatric, medical, sleep disorders must also be sought and evaluated. Interestingly, dopaminergic agents as monotherapy were effective in some trials. Success with combinations of dopaminergic and opioid drugs, with the addition of sedatives, has also been reported in some case reports.

중증도에 따른 아벨리노 각막이상증의 공초점주사현미경 소견

박영민,김호윤,이종수,Young Min Park,MD,Ho Yun Kim,MD,Jong Soo Lee,MD,PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.3

Purpose: In this study we analyzed and objectified the characteristics of the Avellino corneal dystrophy patients considering disease severity using in vivo confocal microscopy (IVCM). Methods: Each corneal layer of 36 eyes in 18 patients with Avellino corneal dystrophy was examined using IVCM (ConfoScan 4.0, NIDEK, Co. Ltd., Albignasego, Italy). Patients were classified into 3 groups based on disease severity (mild, moderate, or severe). Results: In the mild group, hyper-reflective granular deposits without dark shadows were observed in the anterior stroma. As the disease progressed, corneal deposits were also found at the posterior stroma and epithelium, and clusters of hyper-reflective corneal deposits resembling stromal opacity were noted. The range of corneal deposits measured using Z-scan optical pachymeter was 111.14 ± 30.95 um in the mild group, 157.47 ± 25.00 um in the moderate group, and 193.42 ± 52.23 um in the severe group (p < 0.05). Conclusions: The origin of the corneal deposits in Avellino corneal dystrophy may be related to corneal stromal cells and distributed from the corneal epithelial layer to the stromal layer. IVCM might be useful for the standardization of disease severity by digitalizing the range of deposits. J Korean Ophthalmol Soc 2014;55(3):361-367