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윤병남,나정호 대한신경과학회 2007 대한신경과학회지 Vol.25 No.3
Background: The intravenous thrombolysis is a well established treatment of acute ischemic stroke. However, baseline prognostic factors were poorly identified by previous studies. Methods: From January 2001 to May 2006, prospective data of 121 patients treated with intravenous tissue plasminogen activator (tPA) were collected. The clinical, radiologic, transcranial Dopper (TCD) and laboratory finding were evaluated. Clinical assessment was done by National Institutes of Health Stroke Scale (NIHSS) for one week, and by modified Rankin Scale (mRS) at baseline for three months. Early improvement was defined as the complete resolution of the neurological deficit or an improvement of ≥ 4 points by NIHSS within 24 hours, and good outcome as mRS score of ≤ 2 at three months. We assessed the possible relationship of the factors with early improvement and good outcome, and also analyzed the correlation of TCD grade with NIHSS score. Results: On univariate analysis, younger age, absence of abnormal CT findings (hyperdense middle cerebral artery sign [HMCAS], focal hypodensity > 33% of total MCA territory) were significantly associated with early improvement. Good outcome was associated with younger age, lower levels of baseline NIHSS score, mean blood pressure, fasting glucose, lipoprotein (a), and normal CT finding. Multivariate analysis revealed age < 66 years and no HMCAS as independent predictors of early improvement. Thrombolysis in brain ischemia grade by TCD monitoring significantly correlated with NIHSS score for 24 hours. Conclusions: These results suggest that younger age and normal CT findings are important prognostic factors of acute thrombolytic therapy.
TDX-1의 시험자동화를 위한 Test Environment 의 구현
윤병남,노철우,이우섭,Yun, Byeong-Nam,No, Cheol-U,Lee, U-Seop 한국전자통신연구원 1987 전자통신 Vol.9 No.1
본고는 TDX-1의 기능 및 시스팀 시험을 시험전용 컴퓨터를 사용하여 자동화시켜, 체계적이고 능률적인 시험수행과 test quality를 보장할 수 있는 test environment system에 대해 그 기능들의 설명과 그에 대한 implement 방법 및 logical, physical structure를 소개하였다.