여러 종류의 고양이 상피 항원에 대한 피부시험 결과 및 순수도 비교

안영민,임성희,박해심 대한천식알레르기학회 1990 천식 및 알레르기 Vol.10 No.3

To evaluate the relatively high skin test reactivities to cat fur(CF) allergens compared to clinical history and RAST score, skin prick test (SPT) was done concurrently with three available commercial CF extracts(B, T, A Co)in Korea and the correlation of RAST score was evaluated. There were significant differences of SPT reactivity in CF extracts(B: 66.1%, T: 11.9%, A : 11.9%)but the results of T&A companies were comparable and correlated well with RAST rea- ctivity(T, A: 85.7%, B: 26.1%) and clinical symptoms(57.1%) and contact history(71.4%). RAST inhibition test with B, T and Korean CF extracts to D, farinae and D pteronyssinus revealed some inhibition by CF extracts(of B Co. DP 34% DF 2 1. %), but no inhibitions were noted by T and Korean CF extracts, With enzyme linked immunosorbent assay, Der p I was measurable(550ng/ml) and Der f I was also detected(6.5ng/ml) in B-CF extracts but none was found in T and Korean extracts The proportion of house dust mites was similar to the level of Der f I and Der p I in English house dust extrats. Contamination of B-cat fur extracts with house dust mites would be significant. So it is difficult to justity the use of such commercial CF extracts as diagnostic agents and further study on the allergen content must be done in other extracts, such as dog hair or mixed threshing dust which has high SPT positivity compared to clinical hstory

수면 장애와 급성 영아사망증후군

안영민 대한소아알레르기호흡기학회 1996 Supplement Vol.6 No.2

N/A

유무상통(有無相通)

안영민 민족21 2010 민족21 Vol.- No.-

특집: 2022 미디어 이슈&트렌드 회고와 전망 - 기획위원회 좌담

안영민,강신규,김정현,강정수,김용희,한정훈,노동환,박종진,이상오,송현호 한국방송통신전파진흥원 2023 미디어 이슈&트렌드 Vol.- No.53

울금약침(鬱金藥針)이 백서(白鼠)의 간손상(肝損傷) 회복(恢復)에 미치는 영향(影響)

안영민,박희수,Ahn Young-Min,Park Hee-Soo 대한침구의학회 1998 대한침구의학회지 Vol.15 No.2

These studies were carried out to observe the effect of Aqua-acupuncture with Woolgum extract on the recovery from liver injury of rats. The liver injury of rats induced with 0.5ml/200g carbon tetrachloride. The Aqua-acupuncture with Woolgum extract solution inserted into corresponding locus of the Kansu(BL18.) in Rats. Experimental group was divided into 4 groups: Normal group, $CCI_4$-intoxicated group, Saline treated group after $CCI_4$-intoxicated and Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated. Biochemical assays for each serum enzyme activity of GOT, GPT, LDH, total protein, triglyceride, albumin, WBC, neutrophils, lymphocyte were performed. The results were as follows : 1. GOT was decreased with statistical significance in the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated. In GOT activity, the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated showed higher level significant compared with the saline aqua-acupuncture treated group after $CCI_4$-intoxicated. 2. GPT was decreased with statistical significance in the Woolgum aqua-acupuncture treated after $CCI_4$-intoxicated. In GOT activity, the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated showed higher level significant compared with the saline aqua-acupuncture treated group after $CCI_4$-intoxicated. 3. LDH was decreased with statistical significance in the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated. 4. Total protein increased with statistical significance in the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated. 5. Albumin was increased with statistical significance in the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated. The saline aqua-acupuncture treated group after $CCI_4$-intoxicated was not recognized as compared with $CCI_4$-intoxicated group. 6. Triglyceride was increased with statistical significance in the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated. 7. WBC was decreased with statistical significance in the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated. In WBC count, the Woolgum aqua-acupuncture higher level significant compared with the saline aqua-acupuncture treated group after $CCI_4$-intoxicated. 8. Lymphocyte was decreased with statistical significance in the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated. 9. Neutrophils was increased with statistical significance in the Woolgum aqua-acupuncture treated group after $CCI_4$-intoxicated. The saline aqua-acupuncture treated group after $CCI_4$-intoxicated was not recognized as compared with $CCI_4$-intoxicated group. From above results, it is suggested that the Woolgum aqua-acupuncture had significant effects on the injury induced by $CCI_4$.

소아 결핵 진단에 있어서 결핵 특이항원자극 인터페론 감마 측정검사의 임상적 의의

안영민,이희우,박화영,손근찬 대한소아감염학회 2010 Pediatric Infection and Vaccine Vol.17 No.2

Purpose : The purpose of this study is to evaluate the usefulness and limitation of QuantiFERON-TB Gold (QTB) for diagnosis of latent tuberculosis in children. Methods : The medical records of 112 children who were tested by tuberculin skin test (TST) and QTB for detection of latent tuberculosis (TB) in Eulji General Hospital during the period from January 2007 to June 2009 were retrospectively reviewed. Results : Of the 112 participants, the clinical TB group included 15 (13.4%), the contact group included 43 (38.4%), and the non-contact group included 54 (48.2%). Positive rates of TST and QTB were 100% and 80% in the clinical TB group, 64%and 14% in the close contact group, 27% and 0% in the casual contact group, and 52% and 2% in the non-contact group,respectively. Sensitivity of QTB was 80.0% and specificity was 92.6%. Agreement between QTB and TST was poor (κ=0.209). We also confirmed that the positive rate of QTB increased as the age of the patient increased (P =0.011). A QTB indeterminate result was observed in 11 (9.8%) subjects. QTB was retested in 15 subjects. In 5 of the 6 subjects who had positive results initially, positive results persisted for a median 2.2 months after termination of treatment. Conclusion : Although QTB was associated with several problems, including low sensitivity and a high rate of indeterminate results, it had clinical importance due to its high specificity. We found good correlation with regard to exposure and QTB positivity, including that of young children under 5 years of age. However, clinical application of interferon-γ releasing assay for young children for diagnosis of active and latent tuberculosis will require additional prospective studies. 목 적 : 본 연구는 소아에서 QuantiFERON-TB Gold (QTB) 검사의 임상적 유용성과 문제점을 평가하기 위해 시행되었다. 방 법: 2007년 1월부터 2009년 6월까지 본원에서TST와 QTB를 시행 받은 소아청소년 112명의 의무 기록을 후향적으로 조사하였다. 결 과: TST와 QTB의 양성률은 각각 59.8%, 15.2%였고, 두 검사의 일치도는 낮았다(κ=0.209). QTB의 민감도와 특이도는 각각 80.0%, 92.6%였다. QTB 양성율은 임상적 결핵군, 긴밀 접촉군, 일반 접촉군, 비접촉군에서 각각 80%, 14%, 0%, 2% 였으며, 판정보류의 빈도는 9.8%였다. QTB 추적 관찰이 시행된 환자 중, 초기QTB 양성이었던 6명 중 5명은 치료 종료 후 평균 2.2개월까지 양성이 지속되었다. 결 론:소아에서 QTB는 민감도가 낮고, 판정보류의빈도가 높다는 단점이 있으나, 특이도가 높은 장점이 있으므로, TST의 특이도가 낮은 점을 보완하여 결핵의 진단 및 치료 결정에 활용될 수 있을 것으로 생각된다.

Treatment of obstructive sleep apnea in children

안영민 대한소아청소년과학회 2010 Clinical and Experimental Pediatrics (CEP) Vol.53 No.10

Obstructive sleep apnea (OSA) in children is a frequent disease for which optimal diagnostic methods are still being defined. Treatment of OSA in children should include providing space, improving craniofacial growth, resolving all symptoms, and preventing the development of the disease in the adult years. Adenotonsillectomy (T&A) has been the treatment of choice and thought to solve young patient’s OSA problem, which is not the case for most adults. Recent reports showed success rates that vary from 27.2% to 82.9%. Children snoring regularly generally have a narrow maxilla compared to children who do not snore. The impairment of nasal breathing with increased nasal resistance has a well-documented negative impact on early childhood maxilla-mandibular development, making the upper airway smaller and might lead to adult OSA. Surgery in young children should be performed as early as possible to prevent the resulting morphologic changes and neurobehavioral, cardiovascular, endocrine, and metabolic complications. Close postoperative follow-up to monitor for residual disease is equally important. As the proportion of obese children has been increasing recently, parents should be informed about the weight gain after T&A. Multidisciplinary evaluation of the anatomic abnormalities in children with OSA leads to better overall treatment outcome.

계란 알레르기가 있는 환아들에서 알레르기 질환의 동반유무와 예후에 영향을 미치는 인자들에 대한 연구

안영민,신우종,김승연 대한 소아알레르기 호흡기학회 2004 Allergy Asthma & Respiratory Disease Vol.14 No.1

청소년의 사회적 관심이 불안에 미치는 영향 - 자기격려의 매개효과를 중심으로 -

안영민,김원중 한국교류분석상담학회 2017 교류분석상담연구 Vol.7 No.1

본 연구의 목적은 청소년을 대상으로 사회적 관심과 불안 간의 관계에 자기격려의 매개효과 를 알아보는데 있다. 연구대상은 H군에 소재하고 있는 3개의 인문계 고등학교에서 임의 표집 을 하여 각 고등학교 1, 2학년을 대상으로 2017년 2월에 설문조사를 실시하였다. 연구문제를 해결하기 위해 사용한 분석방법은 t-test, ANOVA, Pearson의 상관분석이며, 매개효과 검증은 Baron과 Kenny(1986)의 3단계 절차에 따랐다. 연구 결과는 다음과 같다. 첫째, 기초통계로 고등 학생의 사회적 관심과 자기격려, 불안의 평균, 표준편차를 알아보았으며, 성별에 따른 차이검 증 결과, 사회적 관심과 불안이 차이를 보였으며, 여학생이 남학생보다 사회적 관심이 강하며, 불안을 적게 느끼는 것으로 볼 수 있었다. 둘째, 사회적 관심, 자기격려, 불안의 변인간의 상 관관계를 조사한 결과, 청소년의 사회적 관심은 자기격려와 정적 상관을 보였고, 불안과는 부 적인 상관을 보였다. 자기격려는 불안과 부적인 상관을 보였다. 셋째, 사회적 관심이 불안에 미치는 영향에 대해 자기격려는 완전 매개역할을 보여, 사회적 관심은 자기격려와 함께 작용 을 할 때는 자기격려를 거쳐 불안을 낮추는 간접적인 효과만을 지니고 있음을 알 수 있었다. 사회적 관심이 행동적 자기격려 및 정서적 자기격려와 함께 작용을 할 때는 불안을 낮추는 직접적인 영향과 행동적 자기격려와 정서적 자기격려를 통한 간접적인 영향을 함께 가지고 있는 것이다. 후속연구로 자기격려프로그램을 개발하여 변인들의 관계를 다중회귀분석으로 검 증할 필요가 있을 것이다.

상부 요추간판 탈출증과 동반된 척추 수막낭종증 : Case Report

안영민,박형천,조용은,윤도흠,오성훈,김영수 대한신경외과학회 1990 Journal of Korean neurosurgical society Vol.19 No.5

A case of spinal extradural meningeal cyst associated with the high lumbar disc herniation is reported. The cyst located in posterior extradural extradural space between T12 and L1 vertebrae with L 1/2 intervertebral disc herniation. There was neither osteum and communication to the spinal subarachnoid space. The magnetic resonance imagmg(MRI) was useful for the diagnosis of this isolated extradural cyst.