신라검무 및 동일강도의 트레드밀 운동시 심박수, RPE 및 혈중 젖산농도 변화의 비교

오향란,안나영,김기진 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

This study was performed the comparison of physiological function between a sword dance and treadmill running, For the positive factors of sword dance through physical activity and music component on the psycho-hysiological change. Subjects were consisted of 20-aged 16 female sword dancer of 2 groups, as skillful dancer group(n=B) and novice group(n=B), The results were as follow: In graded maximal testing, VO₂max, anaerobic threshold, and recovery capacity after maximal exercise in skillful group showed a higher than novice group. Change of heart rate during a sword dancing is almost similar level to optimal intensity in aerobic exercise program, so sword dance could be suggested an effective exercise program Physiological stimulus to cardiopulmonary function is different response as the different career of sword dance, because novice group showed a significant(p<.05) higher heart rate in sword dance than treadmill running. Blood lactate concentration showed a similar response between sword dancing and treadmill running in both 2 groups. Novice group showed a higher RPE in sword dancing than treadmill running, but skillful group showed a lower RPE in sword dancing than treadmill running. These results mean that the acquainted level of sword dance affected to the psychological response during sword dancing In these result, hypothesis of the similar blood lactate change between sword dancing and treadmill running could be accepted, but RPE is different response as the different career of sword dance.

경기도 외국인학교 현황 및 교육요구 분석

홍영란,최금진 연세대학교 교육연구소 2005 미래교육학연구 Vol.18 No.1

본 연구는 외국인 투자기업, 임직원의 생활 기초 인프라로써 경기도 지역의 외국인학교 현황을 파악하고, 경기도 지역 내 거주하고 있는 외국인학교 수요자들의 교육요구를 분석하는 데 그 목적이 있으며, 연구결과는 외국인 생활 여건 개선 차원에서 외국인들의 자녀 교육문제 해결에 일조할 수 있을 뿐만 아니라 장기적으로는 외국인 생활환경 개선을 통한 외자유치에도 일익을 담당할 수 있을 것이다. 교육요구 조사 결과, 경기도의 거주 외국인은 꾸준히 증가하고 있는 데 비해 경기도 내에 우수한 교육 프로그램과 시설을 갖춘 외국인학교는 크게 부족함에 따라 외국인학교 추가 설립의 필요성이 적극 제기되고 있다. 외국인들의 자녀교육 문제 해결을 위해서 뿐만 아니라, 전반적인 외국인 생활환경 개선을 통한 외자유치를 위해서도 외국인학교의 추가 설립은 필요하다고 할 수 있다. 결국, 경기도 차원에서 중점 추진하고 있는 외국인 투자유치 및 기업하기 좋은 환경 조성을 위해서는 외국인 교육여건 개선이 수반되어야 하며, 외국인학교 추가 설립은 경기도 내 외국인 교육환경 개선을 위한 직접적이고 효과적인 방안이 될 수 있음을 알 수 있었다. The purpose of this study was to catch the present conditions of foreign school in Gyeonggi-do and to analysis the needs assessmemt of foreign school. The result of this research will be a help to improve the educational environments of foreigner and to attract foreign capital and to create a highly competitive and successful business environment increase investment of foreigner. Based upon a research, foreigners dwell in Gyeonggi-do were increased but quality school run short. It was necessary to found an additional foreign school in Gyeonggi-do. A foreign school is a key element in the investment decision for foreign employees as they seek quality education for their school-age dependent children. These employees expect good facilities, excellent curriculum and professional instruction for their children. Gyeonggi-do should be committed to establishing all the infrastructure elements necessary, including an exemplary foreign school, to attract foreign capital and to create a highly competitive and successful business environment. An additional foreign school will be a help in providing a better environment for foreign education in Gyeonggi do.

저압 MOCVD법에 의한 (100)-GaAs 기판 위의 Ga_xIn(1-x)P 성장과 특성

전성란,손성진,조금재,박순규,김영기 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.17 No.-

x??0.51인 Ga_xIn_(1-x)P 에피층을 저압 MOCVD 성장법으로 TEGa(triethylgallium), TMIn(trimethylindium) 등의 MO(metalorganic) 원료와 PH_3(phosphine)를 사용하여 GaAs(100) 기판 위에 성장하였다. 성장조건에 의한 표면 morphology, 결정결함, 성분비, PL spectra, 운반자 농도와 이동도 및 DLTS spectra와 같은 성장층의 특성을 관찰하였다. 650℃의 성장온도와 V/Ⅲ 비, 즉 TEGa와 TMIn 두 원료의 유량에 대한 PH_3의 유량비가 160∼220일 때 가장 좋은 성장표면을 나타내었다. 성장률은 PH_3의 유량변화에 아무런 영향을 받지 않음을 알 수 있었다. Ga_0.51In_0.49P 에피층과 기판의 격자상수 차에 의한 격자 부정합 Δa_⊥/a_0은 약 (3.7∼8.9)×10 exp (-4)이었으며 실온과 5K에서 에피층의 PL 피크 에너지는 각각 1.85 eV와 1.9 eV였다. 성장층의 운반자 농도와 이동도는 V/Ⅲ 비에 따라 달라지는데 그 비가 120에서 220으로 증가함에 따라 농도는 1.8×10 exp (16) ㎝^-3에서 8.2×10 exp (16) ㎝^-3로 증가하였고 이동도는 1010 ㎝/V·sec에서 366 ㎝/V·sec로 감소하였다. Epitaxial layers of Ga_xIn_(1-x)P with x??0.51 were grown on the GaAs substrates oriented 2℃ off (100) toward <110> by low pressure MOCVD growth technique using triethylgallium (TEGa), trimethylindium (TMIn) and phosphine (PH_3). Surface morphology, crystal defects, composition, photoluminescence spectra, carrier concentration and DLTS spectra of the grown layers were investigated. Good quality epilayers with featureless surface were obtained at growth temperature of 650℃ and V/Ⅲ ratio, i.e., PH_3 flow rate divided by the sum of TEGa and TMIn flow rates, of 160 to 220. The growth rate turned out to have no dependence on phosphine flow rate. The lattice mismatchs Δa_⊥/a_0 between grown Ga_0.51In_0.49P epilayer and GaAs substrate were (3.7∼8.9)×10 exp (-4) and the PL peak energies of the epitaxial layer at room temperature and 5K were 1.85 eV and 1.9 eV, respectively. With increasing V/Ⅲ ratio i.e., phosphine flow rate, from 120 to 220, the carrier density and mobility of undoped epitaxial layers increased from 1.8×10 exp (16) to 8.2×10 exp (16) ㎝^-3 and decreased from 1010 to 366 ㎝/V·sec, respectively.

면접조사를 통한 초등학생의 영양교육 실태 및 실천도 조사

오유진,이영미,김정현,안홍석,김정원,박혜련,서정숙,김경원,권오란,박혜경,이은주,성현이 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.4

This study investigated the experience and practice of elementary school students on nutrition education. The data were collected from 217 male and female students attending 5-6th grade elementary schools in Seoul and Kyunggi-Do from March to June 2007, interviewing face to face by a nutrition teacher and 3 interns of a nutrition teacher. The results were as follows: 86.5% of the subjects learned about ‘Table etiquette’, ‘Reasons for eating fruits and vegetables’ (78.7%), ‘Food waste and environment’ (72.3%), ‘Healthy snacks’ (55.7%), ‘Food sanitation’ (52.3%), ‘Food culture of foreign countries’ (48.1%). Nutrition education experience was significantly different by gender. A total of 43.5% boys responded that they never learned about ‘basic food preperation’ (p < 0.01). They had learned ‘Nutrients for body’ and ‘Food waste and environment’ in school, ‘Healthy weight loss’, ‘Food culture of foreign countries’, ‘Food circulation’ on television, Most content (‘Table etiquette’, ‘Simple cooking’, ‘Food sanitati n’, ‘Eating behaviors for health’, ‘Reasons for eating fruits and vegetables’, ‘Healthy snacks’) was learned from parents. The practice after nutrition education was higher in ‘Table etiquette’ (2.14), ‘Eating fruits and vegetables’ (2.07) than others compared with education experience. The most reason of non-practice on nutrition information was ‘Troublesome’. In ‘Nutrients for body’, a boy answered ‘Difficult for practice’ 20.0%, a girl answered ‘Difficult to understand’ 32.6%, showing a significant difference between the gender groups (p < 0.001). They remembered the ‘Nutrients for body’ (49.6%), ‘Food sanitation’ (44.5%) because of ‘important content’,‘Basic food preparation’ (40.6%), ‘Food culture of foreign countries’ (36.3%) because of ‘interesting content’, ‘Healthy weight loss’ (52.0%), ‘Eating behavior for health’ (44.5%) and ‘Healthy snacks’ (33.7%) because of ‘need for my health’.

셀레콕시브 및 그 합성유도체들의 항암활성 스크리닝

박정란,강진형,구효정,노지영,류형철,박상욱,고동현,조일환,이주영,황다니엘,김인경 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2

Selective COX (cyclooxygenase)-2 inhibitors including celecoxib have been shown to induce apoptosis and cell cycle changes in various tumor cells. New inhibitors are recently being developed as chemomodulating agents. We evaluated celecoxib and screened 150 synthetic compounds for anti-proliferative activities in vitro. Effects of celecoxib on COX activity, cell growth, cell cycle distribution, and apoptosis induction were determined in A549 COX-2 overexpressing human non-small cell lung cancer (NSCLC) cells. The COX inhibition of celecoxib increased with concentration up to 82% at 1μM after 24 hr exposure. Forty μM and 50μM of celecoxib induce G_1 arrest, and TUNEL-positive apoptotic cells, respectively. Among 150 compounds, several compounds were selected for having greater COX-2 inhibitory activity and higher selectivity than celecoxib with growth inhibitory activity. Celecoxib showed concentration-dependent COX inhibitory activity, and ability to induce cell cycle arrest and apoptosis in human NSCLC cells in vitro. Among synthetic analogues screened, several compounds showed promising in vitro activity as COX-2 inhibitory anticancer agents, which warrant further evaluation in vitro and in vivo.

주부의 댄스스포츠 참여가 심리적 하위요인에 미치는 영향

김경란,김성복,정진영,이경일 한국스포츠리서치 2001 한국 스포츠 리서치 Vol.12 No.4

The purpose of this study is to investigate the relationship between house wife's participation on dance sports, marital communication and marriage satisfaction. Specifically, it aims to examine: The influence of the dance sports involvement on marital communication, and marriage satisfaction. The subjects of this study was selected by cluster random sampling of involvement(participation 561, non-participation 177) in dance program facility of Seoul, Kyung-ki, Daejun, and Kwang-ju. The survey questionnaires were used to collect the data. The questionnaire for the formalization factor marital communication, had been developed by Lee(1991). And also the marriage satisfaction had been developed by Kwon & Chei(1998). The statistical methods such as multiple regression analysis. From the analyses of the data, the study reached the following conclusions: Marital communication and marriage satisfaction of dance sport participant house wife are partially influence marriage satisfaction.

전공의들의 직업적 유해인자 및 직업만족도

송혜란,김진하,변주현,이광영,이덕희,김호찬 大韓産業醫學會 2003 대한직업환경의학회지 Vol.15 No.3

목적: 전공의는 여러 유해인자에 노출되어지고 있으며 과중한 업무로 인한 수면 부족에 시달리고 있다. 본 연구는 전공의의 건강상태의 기초 자료를 제공하고 향후개선 방안을 도출하기 위하여 시행하였다. 방법: 연구대상은 2000년 3사관학교와 국군군의학교에 입소한 전체 1,316명 중 전공의 수련과정 없이 입대한 의사와 치과의사, 한의사를 제외한 881명을 대상으로 설문지를 배포하여 784부(회수율: 89.0%)를 회수하고 이중 분석이 가능한 704(79.9%)명의 자료를 최종 분석하였다. 결과: 월평균 당진횟수는 레지던트 1년차에서 19회 정도이었다. 당직 시 평균 수면시간은 레지던트 1년차에서 4시간미만 이었다. 수련기간 동안 전공의의 20%이상에서 방사선, 레이저, 살균소독제, 마취가스, 항암제에 노출되었으며 예방대책은 방사선과 레이저의 노출의 경우 35%정도를 제외하고는 10%내외로 조사되었다. 연구대상자중 91.1%에서 수련기간 동안 주사침이나 시술에 의해 손상을 입었으며 그 중 본인이 감염된 경우는 HBV 2.3%(4명), HCV 0.6%(1명)으로 조사되었다. 응답자의 28.4%에서 자신의 직업에 불만족 하였으며 96.5%가 과중한 업무부담을 느꼈고 69.5%가 동일한 임금수준에서 직업을 바꾸고자 한다고 응답하였다. 결론: 전공의는 수련기간 동안 물리적, 화학적, 생물학적 유해인자에 노출되고 있었으나 이에 대한 보호나 예방대책은 거의이루어지지 않고 있었으며 과중한 업무부담으로 수면부족을 초래하여 가장 중요한 환자 진료에 지장을 받고 있었다. 수련기간 동안 대다수가 의사로서 직업에 대한 흥미를 가지고 있었으나 업무부담과 진료이외의 업무 등으로 소득과 조건이 비슷하다면 다른 직업을 선택하고자 하였다. 이상의 결과를 토대로 전공의들을 위한 유해인자의 보호대책 및 예방대책을 마련하며 과중예방대책이 마련되어야 하고 업무환경개선 및 업무로 인한 건강장해에 대한 정당한 보상이 향후에 마련되어야 할 것이다. Objects: Residents are exposed to various hazards and harassed by sleep dificiency due to overwork. This study was performed to outline the health condition of residents and develop the ways of improving it. Mehtods: A questionnaire was distributed to 881 army doctors who enrolled at the Korea Third Military Academy and The Armed force Health Service School in 2000 with the exception of medical doctors who joined the armed service without going through intern and resident periods, dental and oriental medical doctors. 784(89.0%) of the 881 questionnaires were resident of which 704 cases (79.9%). This should actually be 89.0% were regarded for analyses as being reliable data. Results: More than 20% of residents were exposed to radiation, laser, disinfectants, anesthetic gas, and anticancer drugs during their training periods with preventive neasures for each of these hazards taken in about 10% of the cases of the lesser hazards but in about 35% for the hazards from radiation and laser. 91.1% of residents had experience of needlestick injuries during theirtraining periods with over 36.3% being exposed to patients with infection during that time. The cases contracting HBV and HCV diseases due to pricking are 2.3% and 0.6% respectively. The average number of night duties per month during a one-year resident's period was about 10. The average sleeping time on duty during a one-year residents was less than 4 hours. 28.4% of respondents were not satisfied with their occupation, 96.5% delt tired from overwork and 69.5% wanted to change their occupation to another that would pay the same salary. Conclusion: Residents are exposed to harmful physical, chemical and biological factors, but the preventive care seldom undertaken. In addition, their overwork brings about lack of sleep which causes them problems when giving medical treatment to patients during their training periods. Despite the resident's interest in an occupation as a doctor, many intend to select other occupations if they can receive the same salary. According to the above results, preventative systems and measures should be prepared with environmental improvements for residents, and proper rewards for their overwork should be accomplished

Serious adverse events during clinical trial for pharmacokinetic interation between telmisartan and chlorthalidone in healthy Korean subjects: A case report

( Sook Jin Seong ),( Young Ran Yoon ),( Mi Sun Lim ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-

Te1misartan is an angiotensin II receptor antagonist and chlorthalidone is a thiazide-like diuret-ics. In this study, we report serious adverse events (SAEs) during clinical trial for pharmacokinetic interaction between telmisartan and chlorthalidone in healthy Korean subjects. Two separate, ran-domized, multiple-dose, two-period, one-sequence studies were conducted at Kyungpook National University Hospital. In part A, 43 volunteers received telmisartan for 7 days, and then chlorthali-done for 14 days (days 8-21). Telrnisartan was co-administered during day 15-21 to evaluate the effects of chlorthalidone on the pharmacokinetics of telmisartan at steady state. A healthy 36-year-old male in part A was referred to the emergency room due to severe nausea and vomiting developed about 3 h after administration of chlorthalidone on day 9. Hypokalemia and QT prolongation were observed during his initial laboratory examination and electrocardiogram (ECG) monitoring in the emergency wilt. Nausea and vomiting improved after conservative management with hos-pitalization for 9 days. We consider that the episodes of excessive nausea and vomiting resulted in hypokalemic state which was potentiated by chlorthalidone. And the hypokalemic state caused the lengthening of the QT interval on ECG.

고객충성도의 측정방법에 대한 이론적 고찰

박진영 ; 석미란 김천대학교 2004 김천대학교 논문집 Vol.25 No.-

The purpose of this study is to abstract problems and suggestions from a theoretical research and an analysis of the recent studies in rela-tion to loyalty. The study shows problems and situations of the loyalty measurement based on the various sides of loyalty as follows: 1. There is a typical difference according to the purpose of research, products and service to the type of loyalty. In various researches, how-ever, measuring tools of loyalty are used as they are depending on the result of former researches. 2. The measurement of loyalty can be measured on various point of view: behavior, attitude, cognition and complexity, as per the prior research. 3. Most frequently used questions on the measuring items of loyalty in domestic research were the intention of repurchase and recommendation to friends and relatives. 4. Methodology that can verify the superiority should be considered through the practical analysis of various measuring tools of loyalty. 5. For further research in the future, it will be needed re-verification of model on the loyalty including the analysis of influential factors that shows the causal relation on the loyalty as well as the measuring method of loyalty.

The effects of antibiotics on the reproductive physiology targeting ovaries in the Asian tiger mosquito, Aedes albopictus

Ha Young‐Ran,Jeong Se‐Jin,Jang Chang‐Won,Chang Kyu‐Sik,Kim Hyun‐Woo,Cho Shin‐Hyoung,Lee Hee‐Il 한국곤충학회 2021 Entomological Research Vol.51 No.2

Mosquitoes have adapted to various environmental conditions. Symbionts with mosquitoes impact this adaptation in different environments. In the field, mosquitoes could get exposed to antibiotics during their developmental period, which could reduce or eliminate their symbiotic microbes. However, the side effects of the antibiotics on the ovary and reproductive physiology of the Asian tiger mosquito, Aedes albopictus remains unknown. In this study, we investigated the effects of tetracycline and combinations of rifampicin and tetracycline at environmentally acceptable levels on the reproductive physiology of ovaries in Ae. albopictus. Rifampicin and tetracycline in combination reduced the hatching rate and fertility of Ae. albopictus compared to the untreated control group. These antibiotics induced histopathological damage and reactive oxygen species production in the ovaries. The combination of antibiotics decreased the expression of surface protein of Wolbachia (WSP) in Ae. albopictus. Additionally, the expression of Toll like receptor 2 (TLR2) and Myd88 were triggered by the combinations. The findings demonstrate the detrimental effects of antibiotics, particularly combinations of rifampicin and tetracycline, on the reproductive capacity of Ae. albopictus females.