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False Information Diffusion in Public Crisis on Interpersonal Network and Intervention Strategies
Zhu Xiaoxia,Hao Jiajia,Hu Haiju 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.10
With the development of economy, the public crisis has been increasing frequently and false information took shape because of the public’s assentation and lack of recognition. The diffusion of false information has intensified the public panic and anxiety. Beside, it may cause secondary damage easily. Therefore, the management department of false information in public crisis information should control the diffusion of the false information quickly in order to reduce the loss. By the diffusion of the network of false information in public crisis based on the scale-free network (BA), this paper defines the nature of each social individual from the perspective of multi-agent. On the basis of these properties, this paper defines the individual opinion interaction rules when communicating. The research concludes that active individuals of information diffusion on interpersonal network are not the people with a great amount of friends, but the ones who have few friends. Nevertheless, the management department of false information in public crisis should maintain a circuitous neutral attitude rather than the “all-or nothing” coercive measures when intervene the diffusion process of the false information diffusion. Besides, the influencing social individuals are the “opinion leaders” who have a wide range of interpersonal communication.
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Yiyi Hu,Yu Feng,Jiayuan Qin,Xiaoxia Zhang,Zhiyong Zong 한국미생물학회 2019 The journal of microbiology Vol.57 No.5
Two strains of the genus Acinetobacter, named WCHAc- 010005 and WCHAc010052, were isolated from hospital sewage at West China Hospital in Chengdu, China. The two strains were found to be resistant to carbapenems due to the presence of carbapenemase gene blaNDM-1. Based on the comparative analysis of the rpoB sequence, the two strains formed a strongly supported and internally coherent cluster (intracluster identity of 98.7%), which was clearly separated from all known Acinetobacter species (≤ 83.4%). The two strains also formed a tight and distinct cluster based on the genuswide comparison of whole-cell mass fingerprints generated by MALDI-TOF mass spectrometry. In addition, the combination of their ability to assimilate malonate but not benzoate, and the inability to grow at 37°C could distinguish the two strains from all known Acinetobacter species. The two strains were subjected to whole genome sequencing using both short-read Illumina HiSeq2500 platform and the longread MinION sequencer. The average nucleotide identity and in silico DNA-DNA hybridization value between the genomes of WCHAc010005 and WCHAc010052 was 96.69% and 74.3% respectively, whereas those between the two genomes and the known Acinetobacter species were < 80% and < 30%, respectively. Therefore, the two strains represent a novel species of the genus Acinetobacter, for which the name Acinetobacter chinensis sp. nov. is proposed, and the type strain is WCHAc- 010005T (= GDMCC 1.1232T = KCTC 62813T).
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( Haiqing Sun ),( Fernando Bravo De Laguna ),( Shuai Wang ),( Fengju Liu ),( Liang Shi ),( Haidi Jiang ),( Xiaoxia Hu ),( Peng Qin ),( Jiajian Tan ) 한국축산학회 2022 한국축산학회지 Vol.64 No.1
We studied the effects of Saccharomyces cerevisiae boulardii CNCM I-1079 (LSB) supple mented to lactating sows on reproductive traits and farrowing duration and to piglets from day 7 of life on post-weaning performance and IgG concentration. Ninety-six Landrace × York shire sows started the trial 5 days before the expected farrowing date. Sows were distributed into 2 groups according to parity number and backfat thickness: control (CON: regular lacta tion diet) and LSB (CON + LSB at 2 × 10<sup>9</sup> colony forming units [CFU]/kg of feed). Seven days after birth, litters were randomly selected from each group and supplemented creep feed with or without LSB at 2 × 10<sup>9</sup> CFU/kg. At weaning, piglets from CON sows were shifted to a com mercial farm and allocated to 14 pens in groups of 25 piglets/pen according to the creep feed supplemented during lactation. Piglets followed a 3-phase feeding program: creep, pre-start er and starter, with or without LSB at 2 × 10<sup>9</sup> CFU/kg LSB in creep and pre-starter, and 1 × 10<sup>9</sup> CFU/kg LSB in starter. The piglets were vaccinated against classical swine fever on days 41 and 72 of life. One day before each vaccination and at the end of the trial, blood samples were collected from 15 randomly selected piglets per treatment and assessed for total IgG. Supplemented sows with non-supplemented litters displayed the lowest backfat thickness loss during lactation (p < 0.05). The LSB supplementation shortened farrowing duration (p < 0.05) and increased feed intake (p < 0.05) during the first week of lactation. The LSB-fed pig lets were heavier at the end of creep (p < 0.05), pre-starter (p < 0.05), and the trial (p < 0.05); grew faster during creep (p < 0.05), starter (p < 0.05), and overall (p < 0.05); and displayed an improved feed conversion ratio during creep (p < 0.05). Total IgG content was higher at days 40 (p < 0.05) and 71 (p < 0.05) in LSB-fed piglets. We conclude that supplementing sows with Saccharomyces cerevisiae boulardii CNCM I-1079 from late gestation until wean ing shortens farrowing duration, increases feed intake, and minimizes backfat losses during lactation. When supplemented to piglet diet, post-weaning performance is improved. This improvement observed could be linked to a better immune status, as suggested by the higher IgG.
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Jiangtao Su,Meng Rao,Heshuang Dai,Le Cai,Fan Ye,Lu Ye,Yuchen Hu,Ban Chen,Xiaoxia Guo 한국고분자학회 2024 Macromolecular Research Vol.32 No.2
In this work, pH/GSH-responsive amphiphilic polymeric prodrug (EDA-GLA/CE/2-FPBA) was successfully prepared and could self-assembled into micelles in an aqueous solution. The EDA-GLA/CE/2-FPBA micelles possessed high stability in physiological condition and were pH and GSH sensitive due to the reversible borate ester bonds and disulfide bonds within the prodrug polymer. The structures of the prodrug polymers were characterized by NMR, FTIR, UV–vis spectroscopy. Transmission electron microscopy and dynamic light scattering measurement indicated that the resulting micelles have desirable size distribution and regular spherical shape. Free active Celastrol can be released under low pH and high GSH environment; In vitro cellular uptake and growth inhibition assays suggested that the blank polymer micelles showed good biocompatibility. EDA-GLA/CE/2-FPBA micelles were more efficiently internalized by monolayer tumor cells and demonstrated superior tumor targeting effects as compared to free Celastrol control. These results demonstrated that the novel prodrug self-assembled dual-responsive nano-delivery platform was able to improve the bioavailability and tumor targeting activity of Celastrol, which provides a basis for further clinical applications of Celastrol and its derivatives.
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