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      • Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

        ( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

        Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

      • 서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

        김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

        Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

      • TFE-EtOH와 TFE-H₂O 混合溶媒속에서 2-염화테노일의 親核性 置換反應

        尹庠基,嚴泰燮,成大東 東亞大學校 大學院 1981 大學院論文集 Vol.5 No.-

        For solvolysis of 2-thenoyl chloride we discussed the solvent effects on rates in TFEEtOH, THE-H₂O solvent mixtures. We have used the More O' Ferrall plots show that transition state variation caused by solvent, changes is consistent with an associative Sn2 mechanism for THE-EtOH binary solvent mixtures and an Sn2 mechanism for THE-H₂O in the solvolysis of 2-thenoyl chloride.

      • 열가소성 Wood-Plastic Composites의 기계적 물성에 미치는 커플링제의 영향

        윤태호,신경섭,황택성,이존태 공주대학교 자원재활용 신소재 연구센터 1999 1차년도 센터 성과집 Vol.1999 No.-

        목분 충진제의 함량을 달리 하고 PE수지를 매티릭스로 하여 wood plastic composites(WPC)를 제조하였다. 또한 매트릭스와 충진제간의 계면결합력을 증가시키기 위하여 커플링제로 phthalic anhydride(PA)를 사용하였으며, 충진제의 충진률과 커플링제 처리가 복합재의 기계적 물성에 미치는 영향과 계면현상을 관찰하였다. 목분의 충진률 30wt%, PA커플링제농도 3wt%일 때 인장강도는 26.37MPa로 최대값을 나타내었으며, 이때 충격강도는 46.24J/m의 최대값을 나타냈다. 또한 WPC는 주사전자현미경 관찰을 통해서 커플링제의 처리농도의 증가에 따라 목분과 PE 수지와의 분산과 결합이 잘 이루어졌으을 확인할 수 있었다. Wood powder as reinforcing fillers and polyethylene as a matrix have been used for wood plastic composites(WPC). In preparing WPC, the coupling agent, phthalic anhy dride(PA) was used in order to increase the interfacial bonding force between matrix and fillers. In this study, the effect of wood powder, PA concentration on the mechanical properties and interfcial phenomena on the composites was eveluated. The tensile strength of 3wt% PA-treated composites reached its maximum value of 25.91 MPa when the wood powder content was 30wt%, and the mximum impact strength of PA-treated composites was 46.24H/m. SEM observation showed that wood powder was well dispersed and bonded well with PE matrix by increasing the coupling agent concentration.

      • 조선시대 충청권에 발생한 황충(蝗蟲)에 대한 문화곤충학

        윤일,문태영,남상호 대전대학교 기초과학연구소 2002 自然科學 Vol.13 No.1

        조선왕조실록을 통하여 황충(蝗蟲) 즉 풀무치로 추정되는 메뚜기의 대발생이 충청권에서는 어떤 양상으로 발생하였는가를 추적하였다. 충청권에서 대발생한 메뚜기는 다양한 형태로 기록되고 있으며, 충청북도보다 충청남도에서 더 많은 대발생이 기록되었다. 그런 원인으로는 충남에 경작지가 많아서일 것으로 추측되며, 경작지는 조선시대의 농경정책이 도작을 적극 권장함에 따라 삼국시대에 대발생하던 산지와 초지의 경계역에서 발생하는 풀무치와는 다른 메뚜기종도 포함될 가능성을 검토하였다. 또 대발생 경향도 우리나라에서는 오랫동안 높은 기온이나 습도 유지가 어려우므로 세대반복에 의한 폭발적인 개체수 증가에 의한 대발생 보다는 동시발생에 의한 밀도의 증가에 따른 군거성향 증가의 가능성을 제시하였다. It was assumed that the outbreaking locusts recorded during the Chosun dynasty were most likely to be Locustu migratorla migrutoriu and its impact on the Chungchung provinces were discussed in entomology and ecology based on historical records. The outbreaking patterns were recorded in various ways. The locusts were more frequently and widely recorded in the southern part than in the northern part of Chungchung provinces. It may be due to the fact that cultivation fields were more in the southern part. It is also suggested here the change of the outbreaking species because the political preference in agriculture encouraged to cultivate rice in Chosun dynasty while not so in ancient three kingdoms a s Shilla. Baekje and Kokuqe. The outbreaking types were also diagnosed. Because of the temperate climatic geography, it is difficult to maintain high temperature and humidity in a considerable period enough to allow locusts repeating their generations in Korea. Therefore, it may be reasonable to incline to the simultaneous hatching leading to high densty of locusts and then eventually to outbreaking .

      • SCOPUSSCIEKCI등재

        악안면 유형에 따른 측모 연조직 양상에 대한 연구

        태기출,김상철,국윤아,권영택 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.5

        본 연구의 목적은 악안면유형에 따라 측모 연조직 양상에 차이가 있는지를 알아보고자 17세 이상의 연령을 가진 다양한 수직적 양상을 보이는 Ⅱ급 및 Ⅲ급 남, 녀 79명을 선택하여 각 계측치를 계측하고 통계처리하여 다음과 같은 결과를 얻었다. 1. Nasolabial angle, interlabial angle, lower lip angle, mentolabial angle, symphyseal angle이 골격성 Ⅱ급군과 Ⅲ급군간에 유의한 차이를 보였고, nasofrontal angle, upper lip angle, mentolabial angle, symphyseal angle이 high angle군과 low angle군간에 유의한 차이를 보였다. 2. 악골의 시상적관계를 나타내는 ANB값이 연조직의 nasolabial angle, symphyseal angle, interlabial angle과 정상관 관계를 보였고, lower lip angle과는 역상관 관계를 보였다. 3. 악골의 수직적관계를 나타내는 SN-GoMe값은 연조직의 mentolabial angle, symphyseal angle, nasofrontal angle, upper lip angle과 정상관 관계를 보였다. 4. 골격성 Ⅲ급군에 비해 Ⅱ급군에서 SN-GoMe값에 따른 측모연조직 양상의 차이가 현저하였다. The purpose of this study was to investigate the variations of the soft tissue profile contour in relation to the skeletal patterns and to confirm the correlation of soft tissue angles to the sagittal or vertical skeletal elements. Lateral cephalograms of 79 cases which were older than 17 years in age, were traced and statistically analyzed The obtained results were as follows: 1. Nasolabial, interlabial, lower lip, mentolabial, and symphyseal angles showed the significant differences between skeletal ClassⅡ and skeletal. Class Ⅲ group, but nasofrontal, upper lip, mentolabial, and symphyseal angles showed the significant differences between high angle and low angle group. 2. ANB value showed the significant positive correlation to nasolabial, symphyseal, and interlabial angles and the significant negative relation to lower lip angle. 3. SN-GoMe value showed the significant positive correlation to mentolabial, symphyseal, nasofrontal, and upper lip angles. 4. Soft tissue profile contour in SK. ClassⅡ group showed greater accordance to SN-GoMe value than those in SK. class Ⅲ group.

      • 5-置換 헤테로고리 酸鹽化物 및 그 유도체에 대한 親核的 置換反應의 速度論的 硏究 : 5-브로모-2-염화휴로일의 가용매분해반응

        尹床基,嚴泰燮,朴鍾烈 東亞大學校 大學院 1979 大學院論文集 Vol.3 No.-

        Kinetics for the solvolytic reaction of 5-bromo-2-furoyl chloride have been studied in dipolar and aprotic solvent mixtures, i.e. acetonitrile-water and acetone-water while that of the reaction rates for the methanolysis are measured in non-aqueous binary solvents, i.e. acetonitrile and acetone with methanol cosolvent respectively by means of conductometery at various temperatures. Experimental results are interpreted in terms of solvent effect with varing the composition of binary mixtures and of the reactivities due to the substituent in the heteroaromatic ring in comparison with non-substituted 2-furoyl chloride. The reactivities and reaction mechanism are also reported by the analysis of activation parameters such as ΔS≠ and ΔH≠. The results are also showed that the rates of solvolysis are found to be faster in acetonitrile-water mixtures than those of it in acetone-water system. These behaviors are comparatively consistent with the order of solvent parameters Z and D values which denoting the polar character and dielectric constant of solvent respectively. The rates of methanolysis are increased with the increase of methanol content in non-aqueous binary mixtures, while those of it in acetonitrile-methanol mixtures are also faster than in acetone-methanol system. The order of reaction susceptibility attributable to the substituent in five-membered heteroaromatic ring is observed as 5-bromo-2-furoyl chloride > non-substituted 2-furoyl chloride because of electron withdrawing effect of the bromine atom in the hetero ring. The mechanistic results of solvolysis for the acid chloride is concluded as SN2 cathegory according to Grunwald-Winstein's and Kivinen's plots, and also as entropy controlled reaction on the basis of activation parameters.

      • KCI등재
      • KCI등재

        정수처리공정상 염소소독부산물형성에 미치는 오존의 영향

        성낙창,박현석,이성식,이용희,이종팔,윤태경 한국환경과학회 2004 한국환경과학회지 Vol.13 No.1

        The effect of ozone on the formation and the removal of disinfection byproducts(DBPs) of chlorination process was studied to elucidate the performance of water treatment process. The samples of raw water, prechlorination process, and preozonation process were analyzed quantitatively according to the Standard Methods for the Examination of drinking water. As a result, most of total trihalomethanes(THMs) which were formed in prechlorine treatment process was not removed in the preozonation process. Most of haloacetic acids(HAAs), haloacetonitriles(HANs), and chloral hydrate(CH) was removed in sedimentation and biological activated carbon(BAC) filtration processes. However, DBPs were increased more or less by postchlorine step. In particular, the formation of THMs and HAAs depends on ozone more than chlorine, but, the formation of HANs and CH depends on chlorine more than ozone. The seasonal variation of DBPs concentration for the year needs to be investigated to study the temperature effect because DBPs strongly depend on temperature among various efficient factors.

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