Acitretin으로 치료된 다발성 거대각질가시세포종 1예

권은선 ( Eun Sun Kwon ),이경근 ( Kyoung Geun Lee ),고병용 ( Byoung Yong Koh ),명기범 ( Ki Bum Myung ),정승현 ( Seung Hyun Cheong ) 대한피부과학회 2017 대한피부과학회지 Vol.55 No.4

Giant keratoacanthoma is an uncommon variant of keratoacanthoma, which may increase to a diameter of several centimeters. Although keratoacanthomas usually resolve spontaneously, giant keratoacanthoma can be invasive and destructive. A 49-year-old man presented with a 5-year history of multiple large hyperkeratotic and crusted plaques and nodules on sun-exposed areas such as the face, ear, hand, and forearm. Some lesions involuted spontaneously, whereas others became rather enlarged. The biopsy specimen revealed horn-filled crater formation, epidermal extending resembling a buttress, and an eosinophilic glassy appearance in the keratinocytic cytoplasm. We treated the lesions with acitretin, and they almost completely resolved after 13 weeks. Here we describe a case of multiple giant keratoacanthoma treated with acitretin. (Korean J Dermatol 2017;55(4):249∼252)

垂直平板과 斷熱壁이 이루는 모서리에서의 自然對流

權純錫,徐龍權,鄭永和,金善政 동아대학교 공과대학 부설 한국자원개발연구소 1989 硏究報告 Vol.13 No.1

Natural convection heat transfer from the corner between a vertical flat plate and adiabatic wall has been studied for various inclination angles of the adiabatic wall and Rayleigh numbers by using Mach-Zehnder interferometer in air. Natural convection heat transfer is increased with increasing the inclination angle of the adiabatic wall. The local Nusselt number is increased to x/L=1/18 and then decreased at θ=30° And 60°, but decreased at θ=90°, 120°, 150° And 180° as the dimensionless plate length increases. The mean Nusselt number at θ=30° Shows minimum and at θ=180° Maximum for constant Rayleigh numbers.

Mokpo-MS를 利用한 F_1用種子 採種方法과 採種能力

權炳善,文溶植,李鍾一 조선대학교 농업연구소 1982 農業硏究 Vol.1982 No.1

成分改良된 Mokpo-MS를 利用하여 F_l用種子 採種方法과 採種能力을 究明코자 實驗한바 MS와 花粉親間 의 交互栽植時에 10a 當 F_l採種量은 어느 組合에서나 다 같이 MS 1 畦, 花粉親 1畦 交互畦栽植에서118~127kg의 F_l採種量을 얻었고 MS 2 畦, 花粉親 1 畦 交互畦 栽植에서는 101~ 118Kg, MS 3 畦, 花粉親 1 畦 交互畦 栽植에서는 86~89Kg의 F_l採種量을 얻었다. The F_1 seed production in per l0a has been produced by 118kg to 120kg with the one row planting of pollen parents and one row alternate planting of Mokpo-MS. The other hand, two rows planting of Mokpo-MS and one row alternate planting of pollen parents has been to produced by 101kg to 118kg and three rows planting of Mokpo-MS and one row alter nate planting of pollen parents has been produced by 86 to kg in F-l seed production.

수직하향핀이 부착된 수평 평판에서의 자연대류 열전달에 관한 해석적 연구

권순석,권용일,양성환 동아대학교 공과대학 부설 한국자원개발연구소 1989 硏究報告 Vol.13 No.2

This study has been carried out to investigate into the natural convection heat transfer from the isothermal horizontal plate with downward projecting fins numerically. The governing equations for the system are solved by the finite difference method and sucessive under relaxation method at Ra=10^(5), Pr=0.71, C_(F)=7.75. Mean Nusselt numbers, velocities, temperatures and stream functions are obtained for various dimensionless fin lengths. The results are as follows ; 1. The dimensionless temperature distributions decrease rapidly in fins and linearly in fluid as x/s increase 2. The mean plate, fin and total Nusselt number are decreased by increasing the dimensionless fin lengths 3. The mean late Nusselt number is less than the mean fin Nusselt number at l/s>8.0 4. The local fin Nusselt number is increased rapidly near the fin tip and that of the fin tip is decreased rapidly by increasing the dimensionless fin lengths.

구활자본『삼국지』의 유통과 변이

권용선 인하대학교 한국학연구소 2005 한국학연구 Vol.14 No.-

입원한 중년기 환자의 건강증상정도와 간호요양원에 대한 인식 조사

권용선,박오장 노인간호학회 2005 노인간호학회지 Vol.7 No.2

Purpose: The purpose of study was to prepare data for establishing the nursing home by understanding the health complaints and the cognition about nursing home in the middle aged patients. Method: Research design was a descriptive survey. The subjects were 186 patients who aged 40-64 and administrated at a hospital in G. City. Data were collected by interview with the questionnaires from Dec. 26, 2003 to Jan. 20, 2004. Data were analysed by Y17frequency, mean, ANOVA. Duncan's test through SPSS. Result: The mean score of the health complaints was 1.60 and the cognition about nursing home was 2.15 of 4 point. The score of health complaints was significantly higher in female, lower educational level, lower monthly income, without spouse. The score of cognition about nursing home was significantly higher in higher educational level, higher monthly income. Subjects responded nursing home has merits of the nursing quality and the cost effect, and it should be near home. Conclusions: The level of health complaints was 40% and the cognition of nursing home was 54% of 100 in the middle aged patients.

국내 살모넬라 분리주에서 spvR 유전자 분포와 단일 뉴클레오티드 다형 연구

권혁준,박경윤,박주연,박용호,김선중,유한상 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

목적 : 지금까지 병원성 살모넬라를 확인하기 위해 분자량이 큰 플라스미드의 존재 유무를 확인하여 왔으나 살모넬라 혈청형 및 검출 방법에 따라 양성율에 큰 차이를 보이고 있고, 일부 병원성 살모넬라 분리주에서 병원성 플라스미드가 관찰되지 않아 spv 유전자들의 유무에 대한 아른 확인방법이 필요하다. 본 실험은 국내 동물 유래 주요 살모넬라 혈청형에서 spvR 유전자의 분포를 알아보고, 병원성 살모넬라 분자진단을 위한 분자표지로써의 가치를 평가하기 위해 실행하였다. 재료 및 방법 : 국내 가축 유래 S. lyphimurium (ST, 26주), S. enteritidis (SE, 10주), S. pullorum (SP, 40주), S. gallinarum (SG, 53주)에 대해 GenBank에 등록된 ST, SE, SP의 spvR 유전자를 비교하여 ST와 SE 간에 차이를 보이는 single nucleotide polymorphism (SNP, 625번 뉴클레오티드)을 포함하도록 시발자를 합성하여 집락-PCR을 수행하였다. 증폭 산물(194bp)은 자동 염기서열장치를 이용하여 염기서열을 결정하였고, 제한효소인 MseI을 사용하여 PCR-RFLP를 실시하였다. 결과 : 집락-중합효소연쇄반응 결과 SP, SG, SE의 모든 (100%) 분리주에서 특이 증폭산물이 검출되었으나 ST의 경우 19주(73%)에서만 증폭되었다. 특히 병원성 관련 플라스미드가 관찰되지 않았던 SP 4주에서 특이적인 증폭산물이 검출되었다. 염기서열 분석결과 SE, SG, SP는 625번 뉴클레오티드에 아데닌을, ST는 구아닌을 가지고 있어 PCR-RFLP를 이용하여 쉽게 구분할 수 있었다. 결 론 : spvR에 대한 집락-중합효소연쇄 반응법은 병원성 플라스미드 검출법보다 SE, SP, SG 병원성 주를 신속하게 검출하는데 유용하고, 625번 뉴클레오티드의 SNP는 ST와 SE, SG, SP를 구분하는 분자표지로 사용될 수 있을 것으로 기대되며, ST에 비해 SE는 진화적으로 SG와 SP에 가까운 것으로 생각되었다. Background : The Salmonella virulence plasmid (spv) genes (spvR, A, B, C and D) on the large virulence plasmids of pathogenic Salmonella serotypes can replace the virulence of the whole plasmid. Recently, virulence plasmid-negative pathogenic Salmonella isolates were isolated. However, positive rates of spv genes among Korean Salmonella serotypes have been obscure. spv genes are conserved in compared to other virulence genes but there are single nucleotide polymorphisms (SNPs) conserved in only certain serotype. Such SNPs are useful for differentiation and understanding evolution of certain serotypes. Materials and Methods : Salmonella serotypes isolated from live stocks [Salmonella typhimurium (ST, 26), S. enteritidis (SE, 10), S. gallinarum (SG, 40) and S. pullorum (SP, 53)] were used for colony-PCR. A primer set covering single nucleotide polymorphism (SNP) at 625th nucleotide of spvR was designed. The nucleotide sequences of amplicons were determined by cyclic sequencing method and RFLP was performed by using MseI. Results : All isolates of SE, SG and SP, including four plasmid-negative isolates, showed specific amplicons but not all of ST (19/26, 73%) were positive to spvR. Based on the nucleotide sequence of 625th nucleotide and PCR-RFLP, SE, SG and SP [A(625)] and ST [G(625)] could be differentiated. Conclusion : spvR can be used as a molecular marker to detect virulent SE, SG, SP and the SNP may be useful for differentiation of SE, SG, SP and ST. According to the SNP study SE may be evolutionarily closer to SG and SP than ST.

수직상향핀이 부착된 등온수평평판에서의 자연대류

권순석,권용일,김선정 東亞大學校 大學院 1990 大學院論文集 Vol.15 No.-

This study has been carried out to investigate the natural convection heat transfer from the isothermal horizontal plate with upward projecting fins numerically. The governing equations for the system are solved by the finite difference analysis and successive over relaxation method at Ra=4000-7000, Pr=0.71, C?=7.75. Mean Nusselt numbers, velocities, temperatures and stream functions are obtained for various dimensionless fin lengths The results are as follows ; 1. The local fin Nusselt number is increased rapidly near the fin tip and that of the fin tip is decreased rapidly by increasing the dimensionlesss fin lengths. 2. The mean plate Nusslt number is decreased by increasing the dimensionless fin lengths and the mean fin Nusselt number shows the maximum value at H/S=2.0 3. The mean total Nusselt number shows the optimum fin length for the maximum heat transfer at H/S=2.0 4. The mean plate, fin and total Nusselt number are increased by increasing the dimensionless fin lengths at H/S=1.0

600합금의 미세조직 변화 및 SCC거동에 미치는 Ce 첨가의 영향

권오철,이용선,임연수,정만교,김정수 대한금속재료학회 2005 대한금속·재료학회지 Vol.43 No.1

High purity model alloys with major composition Ni-15Cr-9Fe-0.03C (600CEO) and Ni-15Cr-9Fe-0.03C-0.04Ce (600CE4) were produced. Using these model alloys the effect of alloying element Ce on the SCC behavior of Alloy 600 was evaluated in a caustic solution. To obtain carbides precipitated on grain boundaries, the thermal treatment was performed on both the solution annealed model alloys. Microstructural examinations using SEM and TEM EDX showed that the same structural carbides, Cr_(7)Cc₃, were precipitated on both the alloys and no significant difference in the amount of Cr depletion along grain boundaries was observed between the two model alloys. However, it was shown that the coverage of grain boundary carbides was higher in the Ce-bearing alloy (600CE4). The SCC susceptibility of the alloys was investigated in 40%NaOH solution at 315℃. Being evaluated in terms of the maximum crack depth, the SCC susceptibility of the alloy turned out to be reduced by the addition of Ce. The increased resistance to the SCC in the alloy 600CE4 was considered to be attributable to the increased coverage of grain boundary carbides. (Received September 30, 2004)

남부지역에서의 양파 수확, 저장 및 유통실태

권병선,이을태,오용비,정동희,이조진 順天大學校 師範大學 附屬 科學敎育硏究所 1996 科學과 敎育 Vol.4 No.-

This study was carried out to find marketing, storage and harvest of onion in southern parts of Korea from Jan. 1994 to Apr. 1994. Early maturing cultivar harvest between 10th and 20th of May but late maturing cultivar harvest between 10th and 20th of June, this period was busy farming season with a shortage of labor. Early maturing cultivar was send out good directly but late maturing cultivar was send out good after shortage the simple store house with the period 7-9 month, and professional seed production farmer are not in here. We hope that this report stimulates research to investigate for the establishment of not only harvesting practices such as varietal improvement, machanical harvesting and disease resistant variety for the storage.