담도 및 췌장 악성종양에서의 CAl9-9의 진단적 가치에 대한 평가

명승재,최승목,김은옥,최호순,이성구,김명환,민영일,류진숙 大韓消化器病學會 1995 大韓消化器病學會誌 Vol.27 No.3

개에서 관절이완과 피부과신장을 특징으로 하는 Ehlers-Danlos 양 증례

이성호,안정선,김인순,곽명순,이종완,박영석,박병권,김인봉,김상기,권건오,조성진 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

Ehler' s-Danlos syndrome or cutaneous asthenia (also known as rubber puppy disease) is an uncommon, inherited connective tissue disorder characterized by loose, hyperextensible, fragile skin. The defect has been recognized in both dogs and cats as well as in humans, mink, cows, sheep and horses. The underlying defect is in the synthesis and/ or maturation of type I collagen and as a result of lack of vascular support. Affected animals often experience subcutaneous hematomas that have long bleeding times. A 4-year-old Yorkshire terri or had a hip dislocation, and another had bilateral medial patellar luxation (grade II), subcutaneous hematomas produced by minimal trauma, and generalized periodontitis. Dogs were diagnosed with symptoms described for Ehler' s-Danlos syndrome by the clinical and histological findings in the skin. And then skin samples were examined clinically by calculating the skin extensibility index. Skin biopsies obtained from the dorsum were examined by light microscopy. Histologically, there was a diffuse moderate in the dermis layer and a loose moderate in the hypodermis layer.

勉菴 崔益鉉의 心主理說 硏究 : 尤庵 宋時烈의 心說에 대한 그의 態度를 중심으로

朴性淳(Park Sung-soon) 고려사학회 2007 한국사학보 Vol.- No.27

조선 말기 衛正斥邪運動의 대표 세력인 華西學派는 宋時烈을 自派의 道統 淵源으로 내세우기를 주저하지 않았다. 화서학파의 首長인 李恒老가 ‘孔子-朱子-宋子’로 이어지는 道統觀을 수립한 이래, 화서학파는 이항로를 직접 송시열의 뒤에 연결시키는 그들만의 독특한 도통관을 정립하였다. 그러나 이러한 도통관이 다분히 恣意的인 것이라는 점은 의심의 여지가 없다. 學統上으로나 學說上으로 화서학파는 오히려 노론 洛學派의 명맥을 계승하였기 때문이다. 송시열을 영수로 하는 이른바 尤庵學派가 權尙夏 - 韓元震으로 이어지면서 이항로가 살던 경기도 楊根과는 거리가 먼 충청도 학계를 대표하는 湖學派로 자리매김했다는 점은 상식에 속한다. 더욱이 화서학파의 영수 이 항로가 주창한 心主理說은 송시열의 心卽氣說과는 완전한 대척점에 서 있었다. 이항로의 제자인 崔益鉉은 송시열을 尊華攘夷論의 상징적 인물로서 높이는 한편으로, 그의 심즉기설을 공개적으로 비판하였다. 그리고 송시열의 심즉기설을 편든 자신의 同門 선배인 유중교에 대해서도 가혹하리만큼 매몰찬 비판을 숨기지 않았다. 그것은 스승인 이항로의 心主理說에 대한 확고한 신념 때문이었다. 최익현의 송시열에 대한 양면적 태도를 통해서, 지금까지 피상적으로만 인식되어져 온 화서학파의 對宋時烈觀을 해명하고, 이항로의 心主理說이 지닌 역사적 위상을 가늠해 보고자 한다. As a symbolic nucleus of the so-called "Depending Orthodoxy and Rejecting Heterodoxy" movement in the late nineteenth century, the Hwaseo School(華西學派) scholars contended that their scholastic father was Song Si-yeol. They indeed held fast to their own view that their academic pedigree was linked directly with Song Si-yeol through Yi Hang-no, one of the most renowned later disciples of Song and the very person who made out their own genealogy of Confucianism, starting from Confucius down to Zhu Xi and Song Si-yeol. It is hard, however, to take it at its word because the Hwaseo School basically succeeded to Nakhak School(洛學派), a branch of the Patriarch's Faction (Noron), in terms of the academic pedigree and their interpretation of human mind. It is well known among scholars that the Dam School(尤庵學派), which comprised of Song Si-yeol and his disciples, was succeeded by the Hohak School(湖學派), whose power base was located in Chungcheong Province and led by leading scholars such as Kwon Sang-ha and Han Won-jin. It is also well known that the theory of simjuri(心主理), which literally means that the subject of human mind is li(理), cannot be compatible with the theory of simjkgi(心卽氣), which literally means that the human mind is qi(氣). Interestingly enough, however, the former theory was developed by Yi Hang-no, while the latter by Song Si-yeol What is more, Choi Ik-hyeon, a disciple of Yi, criticized Song's theory of simjkgi even though he still paid honor to Song as a paragon of the "Depending Orthodoxy and Rejecting Heterodoxy" thought. Choi also criticized Yu Jung-gyo, a senior of the Hwaseo School, for his defending Song's theory of simjkgi. Choi's criticism of Song and Yu suggests that he was fully supporting Yi's theory of simjuri. By examining Choi's ambivalent attitude to Song, this paper provides new understanding of Hwaseo School's view of Song and the historical significance of Yi's theory of Simjuri.

김시습과 성현의 귀신 담론과 원귀 인식

강상순(Kang, Sang-Soon) 우리문학회 2014 우리文學硏究 Vol.0 No.44

본고는 김시습과 성현이 남긴 귀신론과 귀신담을 중심으로 그것이 내포하고 있는 시대적 문제의식과 개별적 특징, 그리고 특히 원귀에 대한 인식 차이 등을 검토해보고자 작성되었다. 이를 위해 우선 김시습과 성현이 귀신론을 제출하였던 15세기적 상황을 간략히 검토하면서, 그들의 귀신론은 무속이나 불교에 기반을 둔 기존의 신앙ㆍ습속이 여전히 막강한 위력을 발휘하고 있었던 당대 사회에 대한 유교적 지식인들의 이론적 대응의 산물이라는 점을 강조했다. 그리고 김시습과 성현의 귀신론이 지닌 개별적 특징에 대해서도 살펴보았다. 김시습은 치열한 이론적인 변증을 통해 당대의 온갖 미신적 사유들과 맞서 그것을 논파하고 성리학적 귀신론을 제시하려는 목적의식이 뚜렷했다. 반면 성현은 성리학적 귀신론을 정론으로 받아들이면서도 재래의 귀신신앙을 관찰, 기록, 포섭 혹은 배제하는 데 더 관심을 기울였다. 다음으로 김시습과 성현의 귀신론과 귀신담에서 원귀가 어떻게 인식ㆍ묘사되고 있는지, 그들의 귀신론과 귀신담 사이의 관계는 무엇인지에 대해 논의 해보았다. 우선 김시습의 경우 귀신론에서는 원귀의 존재론적 근거와 정당성을 인정하지 않았지만, 『금오신화』 같은 귀신담에서는 그들의 내밀한 원망에 충분히 공감하였다. 이러한 귀신론에서의 원귀 인식과 귀신담에서의 원귀 묘사 간의 차이는 김시습이 이론적 담론과 서사적 담론 간의 차이를 충분히 인식하고 적극 활용한 것으로 이해해야 온당함을 주장하였다. 이에 비해 성현의 귀신론과 귀신담은 동일한 사유 패턴과 글쓰기 스타일을 반복하고 있다. 성현은 원귀에 관한 시중에 떠도는 이야기들을 사실적으로 기록하고 있지만, 그것에 어떤 도덕적 정당성을 부여하지도 내밀한 원망에 귀를 기울이지도 않았다. 이처럼 원귀를 그 기괴함에 초점을 맞춰 객관적으로 기술하는 것은 원귀를 풀 길 없는 분노를 기괴하고 포악한 짓으로 해소하는 존재라고 본 그의 이론적 입장과 연관되어 있다. The purpose of this study is to analyze KimSi-seup and Sung Hyun’s discourse on ghosts and recognition of lemures, and to compare the both sides. Their discourse on ghosts was against superstition and amoral which had been prevalent in 15th century. They should be the purpose of Confucian enlightenment, and took on the basis of Neo-Confucian theory of ghosts. Kim’s discourse on ghosts was very theoretical article. Sung’s article on ghosts was descriptive and concrete. Next, their discourse on lemures compared with stories on ghosts. For lemures Kim Si-seup took attitude of theoretical negation, but recognized meaning of existence in his fictional narrative. Sung Hyun described realistic for lemures, but He denied it’s meaning of existence. Kim recognized and utilized the discursive differences of discourse and stories on ghosts. Sung did not understand cause and purposes of lemures.

식이섬유 보충 음료의 섭취와 규칙적 운동에 따른 비만관련 체구성 요인 및 혈중 요인의 변화

임용택,김성수,윤성진,강선영,김재등,박인성,권순욱,이충영 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

The purpose of this study was to investigate the effect of drink including dietary fiber supplementation and regulatory exercise on body composition and blood profile concerning obesity of women. Twenty young healthy but on mild obesity women were participated as a subject, Body composition and blood profile were measured before and after 6 weeks' supplementation and exercise, The results of this study were as follows: First, Body composition concerning obesity such as body weight(p=.0001) and %body fat(p=.0001) after 6weeks' dietary fiber supplementation and exercise was decreased significantly. Second, blood profile concerning obesity such as TC(p=.0001), LDL-C(p=.0001) and TG(p=.0002.) after 6weeks' dietary fiber supplementation and exercise was decreased significantly. This results suggested that drink including dietary fiber supplementation and regulatory exercise should be recommended as a effective method for cure and prevention obesity.

위절제술 환자의 표준진료지침 개발 및 적용 효과

김은희,김철규,이순교,김순덕,이혜옥,권정순,이경미,이민미,심순미,유용만,신종식,강은희,이상일,김병식,오성태,육정환,박수길 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.2

Background : Gastric cancer is the most common malignant tumor in Korea. surgical operation is one of the major treatment modalities for gastric cancer patients. Therefore, gastrectomy is one of the most common procedures in General Surgery. There were variation in length of hospital stay and medical treatment for gastrectomy between three surgeons at Asan Medical Center. Clinical pathways have received considerable attention as a tool for recucing the medical practice variation, increasing the efficiency of care process, and improving the quality of care. The aim of this study was to evaluate the effect of a clinical pathway for gastrectomy in gastric cancer patients. Methods : The clinical pathway for gastrectomy was developed and implemented by a multidisciplinary group in Asan Medical Center. A computerized clinical pathway program was developed and revised after a pilot test. A total of 145 patients underwent gastrectomy by three surgeons at Asan Medical Center. We compared the length of hospital stay, patient satisfaction, and unplanned readmission rate between the pre-pathway group(n=67) and the post-pathway group(n=78). We also investigated the degree of satisfaction among the physicians and nurses who were main end-users of the clinical pathway. Results : The clinical pathway was applied to all target patients. The average length of hospital stay was shortened from 12.7days to 10.6days(p<0.01). The degree of patient satisfaction with the care process changed from 90.3% to 89.2% after the implementation of the clinical pathway, but the difference was of satistically significant(p=0.761). Unplanned readmission rate was 2.9% in the pre-pathway group. More than 90% of physicians and nurses answered that the clinical pathway had been a useful tool in their medical practice. Conclusions : The findings of the study demonstrated that implementation of the clinical pathway for gastrectomy produced substantial reduction in the length of hospital stay while improving the quality of patient outcomes. The computerized clinical pathway program can be used as one of the powerful patient management tools for reducing the practice variations and increasing the efficiency of care process in Korea hospital settings.

연령증가에 따른 혈압요소들의 좌심실비대 및 관동맥질환과의 관련성

박재석,박창규,박미영,박재형,김용현,나진오,신성희,서순용,홍순준,박성미,임홍의,김응주,서홍석,오동주,노영무 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

저용량 Cyclosporine-A와 Diltiazem 병합요법에 의한 신증후군의 관해

김성은,정연순,임학 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.3

Background : Cyclosporine-A (CsA) has been widely used as a treatment of nephrotic syndrome especially in patients with steroid-resistance or steroid-dependence. However, it can be nephrotoxic and its cost might also be a point to be considered. Diltiazem (DZ), one of calcium channel blockers, may have a potential benefit of renoprotection, which decreases acute tubular necrosis of renal transplants. DZ can also be used for reducing CsA dose because it slows down the metabolism of CsA by inhibition of cytochrome P-450 hepatic enzyme. In these points of view, low-dose CsA with DZ combination could be considered as an alternative to nephrotic syndrome treatment. However, such a kind of trial was hardly found so far. The purpose of this study was to evaluate the therapeutic effect of low-dose CsA with DZ in patients with steroid-resistant or steroid-dependent nephrotic syndrome. Methods : Low-dose of CsA (mean 1.7±0.5 mg/kg) and 90 mg of DZ were administered simultaneously to 15 patients of steroid-resistant or steroid-dependent nephrotic syndrome for 6 months with no alteration of dose. Blood pressure, body weight and random urine protein, 24-hour urine protein, serum creatinine, albumin, total cholesterol, and trough level of CsA were analyzed. Results : The random urine protein tended to decrease by CsA treatment. Twenty-four hour urine protein excretion decreased significantly at 6th months of treatment (from 7,211±5,374 mg to 1,094±1,688 mg, n=7, p=0.018). Complete remission was achieved in 10 patients and partial remission in 5 patients. Changes in serum albumin, total cholesterol, hemoglobin, body weight and blood pressure were statistically not significant. Conclusion : Low-dose CsA combined with DZ may be an effective in patients with steroid-resistant or steroid-dependent nephrotic syndrome.

소뇌에 발생한 Nocardiosis : 증례 보고 Case Report

성연상,김상진,박순필,강재규,도종웅 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.6

The authors report a extemely rare case of primary cerebellar nocardial abscess. Cerebral nocardiosis is rare disease and often fatal, and often fatal, and commonly spreaded from nocardiosis of lung or skin. Total excision of abscess and medication with sulfonamide is the treatment of choice. The patient was treated by continuous external dirainage with intermittent irrigation of abscess cavity by sulfonamide and given with sulfonamide for 10 months.