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신혜경,유연옥 啓明大學校 生活科學硏究所 2006 科學論集 Vol.32 No.-
The purpose of this research was to investigated the relation between the young children's creative personality characteristic and the drawing creativity. The subject of this research were 180, 4~6 years old, young children who were attending to day cares, preschools, and elementary schools. In this research, "What kind of person are you?" - The creative characteristic test(Kim, 2002) for examining the young child's creative characteristic features and "TCT-DP(Test for Creative Thinking-Drawing Production)" (Jellen & Urban, 1986) for measuring the young child's creativity were used. Analyzing data were made of average, standard deviatim, ANOVA, correlation which were the output of the creative characteristic test and TCT-DT to find out young children's development of creativity. The results of on this research were belows. First, there was no difference of creative personality characteristic in the age of 4~6. Second, in the each different age, it showed that the creativity seemed to increase steadily ordering the age 4, 5, 6. Third, in the difference between creative personality characteristic and creativity, the young children who had the high scores of creativity were excellent in the characteristic features of confidence, observation, and imagination.
홍나영,유혜경,이주현,석혜정,신혜성,김찬주 服飾文化學會 2003 服飾文化硏究 Vol.11 No.3
The main purpose of this exploratory research was to examine the characteristics of consumers who patronize natural-dyed clothes and their perceptions regarding natural-dyed clothes. Thirty three participants who have worn natural-dyed clothes were interviewed for the study. They were asked about styles and price of natural-dyed clothes they owned, their evaluation on them, and the lifestyles of themselves. Existence of subculture among the interviewes and its characteristics were also probed. The results indicated that natural-dyed clothes are relatively high-priced, mostly of modified hanbok style, and became popular in recent years. Interviewees frequently mentioned uniqueness and comfort as the main benefits of natural-dyed clothes, and expressed dissatisfaction regarding color fastness, easy care and problem of coordination. The consumers of natural-dyed clothes appeared to have strong preferences for environment conservation and Korean traditional culture. They also seemed to form a subcultural group who have commonality in their involvement in Korean cultural activities, mainly tea ceremony.
( Shin-hye Yu ),( Soomin Kim ),( Yujin Kim ),( Seo-eun Lee ),( Jong Hyeok Park ),( Gayoung Cho ),( Jong-cheon Ha ),( Hahnsun Jung ),( Sang-min Lim ),( Kyuboem Han ),( Hong Kyu Lee ),( Young Cheol Kang 생화학분자생물학회 2022 BMB Reports Vol.55 No.3
Inflammation is one of the body’s natural responses to injury and illness as part of the healing process. However, persistent inflammation can lead to chronic inflammatory diseases and multi-organ failure. Altered mitochondrial function has been implicated in several acute and chronic inflammatory diseases by inducing an abnormal inflammatory response. Therefore, treating inflammatory diseases by recovering mitochondrial function may be a potential therapeutic approach. Recently, mitochondrial transplantation has been proven to be beneficial in hyperinflammatory animal models. However, it is unclear how mitochondrial transplantation attenuates inflammatory responses induced by external stimuli. Here, we isolated mitochondria from umbilical cord-derived mesenchymal stem cells, referred as to PN-101. We found that PN-101 could significantly reduce LPS-induced mortality in mice. In addition, in phorbol 12-myristate 13-acetate (PMA)-treated THP-1 macrophages, PN-101 attenuated LPS-induced increase production of pro-inflammatory cytokines. Furthermore, the anti-inflammatory effect of PN-101 was mediated by blockade of phosphorylation, nuclear translocation, and trans-activity of NFκB. Taken together, our results demonstrate that PN-101 has therapeutic potential to attenuate pathological inflammatory responses. [BMB Reports 2022; 55(3): 136-141]
Yu, Shin-Hye,Kwak, So-Hyung,Nguyen, Thi Thanh Hanh,Seo, Ye-Seul,Song, Chaeri,Mok, Il Kyoon,Kim, Doman Springer Netherlands 2018 Biotechnology letters Vol.40 No.2
<P><B>Objectives</B></P><P>To develop preventive canine oral health bio-materials consisting of probiotics and glucanase to reduce insoluble glucan and volatile sulfur compound formation.</P><P><B>Results</B></P><P>Co-cultivation of <I>Enterococcus faecium</I> T7 with <I>Streptococcus mutans</I> at inoculation ratio of 3:1 (v/v) resulted in 25% reduction in the growth of <I>Streptococcus mutans</I>. Amounts of soluble and insoluble glucans produced by <I>S. mutans</I> were decreased to 70 and 55%, respectively. Insoluble glucan was decreased from 0.6 µg/ml in <I>S. mutans</I> culture to 0.03 µg/ml in <I>S. mutans</I> co-cultivated with <I>E. faecium</I> T7 in the presence of <I>Lipomyces starkeyi</I> glucanase. Volatile sulfur compound, a main component of halitosis produced by <I>Fusobacteria nucleatum</I>, was decreased by co-cultivating <I>F. nucleatum</I> with <I>E. faecium.</I></P><P><B>Conclusion</B></P><P><I>E. faecium</I> and glucanase can be combined as potentially active ingredients of oral care products for pets by reducing plaque-forming bacteria growth and their by-products that cause cavity and periodontal disease.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (10.1007/s10529-017-2478-z) contains supplementary material, which is available to authorized users.</P>
혈액투석이 필요한 심한 부종양 고칼슘혈증으로 발현한 식도암
안혜신 ( Hye Shin Ahn ),윤종민 ( Jong Min Yun ),이영복 ( Yeong Bok Lee ),고유미 ( Yu Mi Ko ),이정은 ( Jung Eun Lee ),원혜성 ( Hye Sung Won ),김성수 ( Sung Soo Kim ),김영옥 ( Young Ok Kim ) 대한소화기학회 2015 대한소화기학회지 Vol.65 No.6
Paraneoplastic hypercalcemia without bone metastasis occurs rarely in esophageal cancer. A 75-year-old man was admitted for general weakness and lethargy. Laboratory data showed high serum calcium level (corrected calcium 14.6 mg/dL), low parathyroid hormone level (3.3 pg/mL) and high parathyroid hormone-related peptide level (3.5 pmol/L). Esophagogastroscopy showed a malignant tumor in the esophagus. Histology showed moderately differentiated squamous cell carcinoma. Bone scan showed no evidence of bone metastasis. Since the patient’s calcium levels remained high and mental state did not show improvement despite intravenous fluid therapy, diuretics and intravenous bisphosphonate, hemodialysis was started. After hemodialysis treatment, the serum calcium level subsequently normalized and his mental status improved. Herein, we report a rare case of paraneoplastic hypercalcemia in a patient with esophageal cancer. (Korean J Gastroenterol 2015;65:361-365)
SCOR 모델과 만족도 함수를 이용한 공급 사슬의 성과 측정 프레임워크 개발에 관한 연구
신혜경 ( Hye Kyeong Shin ),홍유신 ( Yu Shin Hong ) ㈜엘지씨엔에스 2007 Entrue Journal of Information Technology Vol.6 No.1
공급 사슬 관리의 중요성이 커지면서, 기업들에게 그들이 속한 공급 사슬의 성과를 측정하고 관리해야 할 필요성이 크게 대두되고 있다. 하여 본 논문에서는 Supply Chain Operations Reference(SCOR) 모델과 만족도 함수를 이용한 공급 사슬의 성과 측정 프레임워크를 제안해 보았다. 우선 공급 사슬을 구성하고 있는 각 조직들의 성과를 측정하기 위해, 단일 기업의 경영 성과를 평가하는 툴인 Balanced ScoreCard(BSC) 구축 Flow를 변형하여 공급 사슬 내 각 주체들의 성과 측정을 위한 Flow를 제안하였다. 이 과정에서 SCOR 모델에서 정의한 성과 지표들 중에서 핵심 성과 지표를 정의하고 구체화하였다. 이렇게 평가된 각 조직들의 성과를 하나의 공급 사슬 성과로 통합하기 위하여 본 논문에서는 만족도 함수, 성과 관리 범위, 기여도 개념 등을 이용한 성과 통합 Flow을 제안하였다. 마지막으로 사례 연구를 통하여 제안된 프레임워크를 실제 공급 사슬에 적용해 보고, 현실적 의미를 도출해 보았다. As Supply Chain Management(SCM) is becoming more and more important, firms need to measure and manage performance of integrated supply chain across several companies. Therefore this paper attempts to propose a framework for performance measurement for supply chain management using Supply Chain Operations Reference(SCOR) model and desirability function. First of all, Balanced Score Card(BSC) building procedure is adopted for evaluating the performance of each organization constituting the supply chain. Especially the supply chain performance metric of SCOR model is used for defining and specifying key performance indicators. To integrate results of each firm into the supply chain performance, the author introduces a flow for integration using desirability function, performance band and degree of contribution etc. The developed framework is applied in a real world case and results are presented at the end.
학교 건축물의 모형실험을 통한 국내지진에 대한 내진보강에 관한 연구
신혜민(Shin, Hye-Min),전아현(Jun, A-Hyun),최혜지(Chio, Hye-ji),팽지영(Paeng, Ji-Yeong),유민지(Yu, Min-ji),이재경(Lee, Jae-gyoung),이현지(Lee, Hyeon-Ji),신경재(Shin, Kyung-Jae) 대한건축학회 2017 대한건축학회 학술발표대회 논문집 Vol.37 No.2
The purpose of this study is to develop various seismic reinforcement through shaking table test and nonlinear analysis of the school building. After the Gyeongju 9.12 earthquake, the government has set a policy to extend the scope of the mandatory seismic design on new buildings and public buildings, and to expand the seismic reinforcement of public buildings with low rate of seismic design. 86% of elementary, middle, and high school buildings surveyed in Korea were found to be vulnerable to earthquakes. Therefore, it is necessary to strengthen the seismic reinforcement of the school buildings that should be used as a disaster evacuation facility.