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      • SCIESCOPUSKCI등재

        Baumann Skin Type in the Korean Male Population

        ( Young Bin Lee ),( Sung Ku Ahn ),( Gun Young Ahn ),( Hana Bak ),( Seung Phil Hong ),( Eun Jung Go ),( Chang Ook Park ),( Sang Eun Lee ),( Weon Ju Lee ),( Hyun-Chang Ko ),( Jee-Bum Lee ),( Hyung Joo K 대한피부과학회 2019 Annals of Dermatology Vol.31 No.6

        Background: Research into the Baumann skin type (BST) has recently expanded, with growing interest in the development of an efficient and effective skin type classification system for better understanding of this skin condition. Objective: We aimed to identify male-specific skin type characteristics with investigation into the distribution of BST by age and region in the Korean male population and to determine the intrinsic and extrinsic factors related to skin type. Methods: A questionnaire was administered to collect information about age, region, working behavior, drinking behavior, smoking behavior, usual habit of sun protection, medical history, and the BST which consisted of four parameters; oily (O) or dry (D), sensitive (S) or resistant (R), pigmented (P) or non-pigmented (N), and wrinkled (W) or tight (T). Results: We surveyed 1,000 Korean males aged between 20 and 60 years who were divided equally by age and region. Of the total re- Background: Research into the Baumann skin type (BST) has recently expanded, with growing interest in the development of an efficient and effective skin type classification system for better understanding of this skin condition. Objective: We aimed to identify male-specific skin type characteristics with investigation into the distribution of BST by age and region in the Korean male population and to determine the intrinsic and extrinsic factors related to skin type. Methods: A questionnaire was administered to collect information about age, region, working behavior, drinking behavior, smoking behavior, usual habit of sun protection, medical history, and the BST which consisted of four parameters; oily (O) or dry (D), sensitive (S) or resistant (R), pigmented (P) or non-pigmented (N), and wrinkled (W) or tight (T). Results: We surveyed 1,000 Korean males aged between 20 and 60 years who were divided equally by age and region. Of the total respondents, OSNW type accounted for the largest percentage and ORPW type the lowest. In terms of Baumann parameters, O type was 53.5%, S type was 56.1%, N type was 84.4% and W type was 57.5%. Several behavioral factors were found to have various relationships with the skin type. Conclusion: The predominant skin type in the Korean male respondents was OSNW type, and the distribution of skin types with regards to age and region was reported to be distinct. Therefore, skin care should be customized based on detailed skin types considering the various environmental factors. (Ann Dermatol 31(6) 621∼630, 2019)

      • KCI등재SCOPUS

        임신한 당뇨환자에서 인슐린 lispro 투여로 저혈당을 예방한 2 예 보고

        임문환(Moon Whan Im),박운호(Un Ho Park),이정은(Jung Eun Lee),고선환(Sun Hwan Koh),임수빈(Soo Bin Im),이정례(Jeong Rye Lee),이지영(Ji Young Lee),황성욱(Sung Ook Hwang),이우영(Woo Young Lee) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.7

        Insulin therapy is indicated in the treatment of gestational diabetic women and overt diabetic pregnant women for hyperglycemia after failure to respond to the diets and exercise regimens. The insulin is administered to mimic normal pancreatic function. The normal pancreas secretes 50% of the total daily insulin as mealtime boluses. This delivery may be mimicked by four-injection-per-day of combination of NPH and regular insulin (RI). Hypoglycemia is a well-recognized complication of intensive insulin therapy in patients with Type Ⅱ diabetes. Recently, it has been reported that insulin-lispro, an analogue of regular human insulin with a peak insulin action achieved with a 1 hour after injection improves postprandial glucose concentration in non-pregnant diabetic patients. Treatment of gestational or diabetic pregnant women with NPH and insulin-lispro has significantly lower postprandial glucose levels without an increase in hypoglycemic events. Here, we report 2 cases of hyperglycemic control with four times daily administration of NPH & insulin-lispro on diabetes in pregnancy, with brief reviews.

      • KCI등재

        SNS 정보 요인이 소비자 구매의도에 미치는 영향에 대한 연구

        이욱(Ook Lee),이건빈(Jian-Bin Li),지명근(Myung-Keun Jee),안종창(Jong-Chang Ahn) 한국산학기술학회 2017 한국산학기술학회논문지 Vol.18 No.7

        소셜 네트워크 사이트는 전자상거래에서 사용자 그룹의 특성을 이용하며, 사이트를 기반으로 사용자에게 더 많은 가치를 창출할 수 있다. 그러므로 본 연구는 중국에서 회원 수가 가장 많은 소셜 네트워크 사이트인 웨이보(Weibo) 사용자를 대상으로 한다. 중국 소셜 네트워크 서비스(SNS; Social Network Service)의 발전 현황을 통해 소비자 구매의도에 영향을 미치는 SNS 정보요인을 도출해 보고자 한다. 본 연구는 댓글 수, 소비자 관여도, 소비자 소구방식 정도가 각각 소비자 구매의도에 유의한 차이가 있는지와 댓글수와 소구 방식이 서로 교호 작용하는 바탕에서 소비자 구매의도에 차이가 있는지에 대해 연구했다. 이를 위해 SNS를 이용하는 사용자를 대상으로 온라인 설문조사를 통해 400명의 샘플을 확보하였다. 응답자들에 대해 SPSS21 통계패키지를 이용하여 신뢰성 분석, 타당성 분석, 그리고 독립표본 t-검정, 이원배치 분산분석을 수행했다. 연구결과, 댓글 수 정도와 이성적인 소구방식은 소비자 구매의도에 대해서 유의한 차이가 있었다. 소비자들은 구매 관여도의 조절에 따라 댓글 수 정도가 구매의도에 차이가 있음을 보여 주었고, 정보 소구방식은 차이가 없다는 것을 발견했다. The SNS website can take full advantage of the characteristics of users to conduct e-commerce. The e-commerce website"s organizing ability will be greatly strengthened by SNS and creates greater value for consumers. This article examined the Chinese largest SNS (Weibo) users as research objects, and combined the development status of SNS in China. This article focuses on the influence to consumer"s purchase intention in three aspects: number of comments, consumer involvement level, and consumer appealing method and examines how the interaction of the number of comments and consumer appealing method affects the purchase intention. An investigation was conducted on 400 users of SNS and using valid questionnaires to perform reliability analysis, validity analysis, independent sample t-test, and double factor variance analysis using SPSS21. The research results indicated that the number of comments and rational appealing method had significant effect on the purchase intention. The mediating or controllingthe purchase involvement level will disturb the influence of the number of comments but will have no effect on the information appealing method.

      • KCI등재

        Impact of postoperative duration of Aspirin use on longevity of bioprosthetic pulmonary valve in patients who underwent congenital heart disease repair

        Tae-Woong Hwang,Sung-Ook Kim,Sang Yun Lee,Seong Ho Kim,Eun-Young Choi,So-Ick Jang,Su-Jin Park,Hye-Won Kwon,Hyo-Bin Lim,Chang-Ha Lee,Eun Seok Choi 대한소아청소년과학회 2016 Clinical and Experimental Pediatrics (CEP) Vol.59 No.11

        Purpose: Generally, aspirin is used as a protective agent against thrombogenic phenomenon after pulmonary valve replacement (PVR) using a bioprosthetic valve. However, the appropriate duration of aspirin use is unclear. We analyzed the impact of postoperative duration of aspirin use on the longevity of bioprosthetic pulmonary valves in patients who underwent repair for congenital heart diseases. Methods: We retrospectively reviewed the clinical data of 137 patients who underwent PVR using a bioprosthetic valve between January 2000 and December 2003. Among these patients, 89 were included in our study and divided into groups I (≤12 months) and II (>12 months) according to duration of aspirin use. We analyzed echocardiographic data from 9 to 11 years after PVR. Pulmonary vale stenosis and regurgitation were classified as mild, moderate, or severe. Results: The 89 patients consisted of 53 males and 36 females. Their mean age was 14.3±8.9 years (range, 2.6–48 years) and body weight was 37.6±14.7 kg (range, 14–72 kg). The postoperative duration of aspirin use was 7.3±2.9 months in group I and 32.8±28.4 months in group II. However, no significant difference in sex ratio, age, body weight, type of bioprosthetic valve, and number of early redo-PVRs. In the comparison of echocardiographic data about 10 years later, no significant difference in pulmonary valve function was found. The overall freedom rate from redo-PVR at 10 years showed no significant difference (P=0.498). Conclusion: Our results indicated no benefit from long-term aspirin medication (>6 months) in patients who underwent PVR with a bioprosthetic valve.

      • KCI등재

        미생물 분리주를 이용한 제비꽃 발효액의 생리활성 변화

        이지영(Ji-Young Lee),오수빈(Su-Bin Oh),최낙식(Nack-Shick Choi),박용운(Yong-Woon Park),강대욱(Dae-Ook Kang) 한국생명과학회 2019 생명과학회지 Vol.29 No.2

        미생물의 발효를 이용하여 제비꽃의 효능과 기능성을 증진시켜 응용을 높이기 위한 목적으로 발효식품에서 분리하고 동정한 B. methylotrophicus CBMB205와 L. pseudomesenteroides NRIC1777 두 미생물을 이용하여 72시간 제비꽃을 발효하면서 12시간 마다 발효액의 총 폴리페놀과 총 플라보노이드 함량, 항산화력, 환원력, 혈당조절과 관련이 있는 α-amylase와 α-glucosidase 저해활성, 비만관련 췌장 리파제 저해활성 등을 측정하고 대조구인 비발효 제비꽃과 비교, 분석하였다. 총 폴리페놀 함량의 경우 Bacillus와 유산균은 대조구에 비해 각각 1.4배 및 1.17배 증가되었고, 총 플라보노이드 함량은 각각 3.2배와 3.4배 증가되었다. 항산화력 비교에서 DPPH 라디칼 소거능은 모두 변화가 없었으나 ABTS 라디칼 소거능의 경우 2.1배 및 1.6배 증가된 것으로 나타났다. 환원력의 경우 Bacillus는 1.6배 높게 나타났으나 유산균은 대조구와 유의적인 차이점이 없었다. α-Amylase의 경우 Bacillus와 유산균은 대조구보다 각각 6배와 3배의 저해율을 보였고 α-glucosidase는 2.9배와 2.6배의 저해활성을 나타내었다. 췌장 리파제에 대해서 Bacillus와 유산균은 대조구에 비해 3.4배와 2.8배 높은 저해활성을 보였다. Bacillus와 유산균으로 발효한 제비꽃은 DPPH 라디칼 소거능을 제외하고 시험한 모든 항목에서 대조구보다 우수한 결과를 얻었다. 따라서 미생물 발효를 통해 항산화력과 관련이 있는 총 폴리페놀과 총 플라보노이드 함량이 증가되고 ABTS 라디칼 소거능, α-amylase, α-glucosidase 및 췌장 리파제에 대한 저해능 등이 대조구에 비해 높아진 결과를 토대로 건강기능식품이나 화장품 첨가제 등으로 이용될 수 있을 것으로 기대된다. The aim of this study was to improve the efficacy and functionality of Viola mandshurica (VM). A water suspension of VM power was fermented for 72 hr with Bacillus methylotrophicus CBMB205 (BM) and Leuconostoc pseudomesenteroides NRIC1777 (LP) isolated from kimchi. The antioxidant activity and reducing power of fermented VM, its total phenolic and flavonoid compounds, as well its inhibitory activity on α-amylase, α-glucosidase, and pancreatic lipase were determined and compared to those of non-fermented VM (NVM), a negative control. The total phenolic and flavonoid compounds of VM fermented with BM and LP were higher than those of NVM by 1.4, 1.17, and about 3 times. There was no difference in 2, 2’-diphenyl-1-picryl hydrazyl (DPPH) radical scavenging activity between fermented VM and NVM. However, there was a 2.1- and 1.6-fold increase in 2, 2’-azino-bis-(3-ethylbenzothzoline-6-sulfonic acid) (ABTS) radical scavenging activity in VM fermented with BM and LP, respectively. The reducing power of BM was 1.6 times as high as NVM, but no significant difference was found between LP and NVM. Fermented VM’s inhibitory activity on α-amylase, α-glucosidase, and pancreatic lipase was much higher than that of NVM. Fermenting VM with BM was superior to fermenting it with LP, except flavonoid content. Taken together, VM fermented with BM could be used as a functional food and as an additive to cosmetics.

      • KCI등재
      • SCOPUSKCI등재

        Impact of postoperative duration of Aspirin use on longevity of bioprosthetic pulmonary valve in patients who underwent congenital heart disease repair

        Hwang, Tae-Woong,Kim, Sung-Ook,Lee, Sang-Yun,Kim, Seong-Ho,Choi, Eun-Young,Jang, So-Ick,Park, Su-Jin,Kwon, Hye-Won,Lim, Hyo-Bin,Lee, Chang-Ha,Choi, Eun-Seok The Korean Pediatric Society 2016 Clinical and Experimental Pediatrics (CEP) Vol.59 No.11

        Purpose: Generally, aspirin is used as a protective agent against thrombogenic phenomenon after pulmonary valve replacement (PVR) using a bioprosthetic valve. However, the appropriate duration of aspirin use is unclear. We analyzed the impact of postoperative duration of aspirin use on the longevity of bioprosthetic pulmonary valves in patients who underwent repair for congenital heart diseases. Methods: We retrospectively reviewed the clinical data of 137 patients who underwent PVR using a bioprosthetic valve between January 2000 and December 2003. Among these patients, 89 were included in our study and divided into groups I (${\leq}12$ months) and II (>12 months) according to duration of aspirin use. We analyzed echocardiographic data from 9 to 11 years after PVR. Pulmonary vale stenosis and regurgitation were classified as mild, moderate, or severe. Results: The 89 patients consisted of 53 males and 36 females. Their mean age was $14.3{\pm}8.9$ years (range, 2.6-48 years) and body weight was $37.6{\pm}14.7kg$ (range, 14-72 kg). The postoperative duration of aspirin use was $7.3{\pm}2.9$ months in group I and $32.8{\pm}28.4$ months in group II. However, no significant difference in sex ratio, age, body weight, type of bioprosthetic valve, and number of early redo-PVRs. In the comparison of echocardiographic data about 10 years later, no significant difference in pulmonary valve function was found. The overall freedom rate from redo-PVR at 10 years showed no significant difference (P=0.498). Conclusion: Our results indicated no benefit from long-term aspirin medication (>6 months) in patients who underwent PVR with a bioprosthetic valve.

      • SCOPUSKCI등재

        우위대망동맥을 이용한 관상동맥 우회술 100례의 임상적 고찰

        송현,임한중,이현우,정종필,신제균,김종욱,박종빈,이재원,송명근,Song, Hyun,Lim, Han-Jung,Lee, Hyun-Woo,Jung, Jong-Pil,Shin, Je-Kyoun,Kim, Jong-Ook,Park, Jong-Bin,Lee, Jae-Won,Song, Meong-Gun 대한흉부심장혈관외과학회 2000 Journal of Chest Surgery (J Chest Surg) Vol.33 No.8

        Background: In an effort t enhance long term patency of coronary bypass grafts, utilization of arterial conduits have been on an icrease. With the same objective, we have been using the right gastroepiploic artery(RGEA)in coronary artery bypass procedures since 1998. The current paper has been undertaken with the aim of assessing the apropriateness, problems, and short term results of using the RGEA as an arterial graft conduit by studying the postoperative clinical results of 100 patients than received coronary artery bypass grafting (CARG) with this artery. Material and Method: Between May of 1998 and May of 1999, an analysis of the mortality, postoperative myocardial infarction, and the need for IABP insertion as a result of low cardiac output were made between 100 consecutive patients undergoing CABG with the RGEA. Result: There was one postoperative death due to cerebral infarction. Postoperative complications/morbidity comprised myocardial infarction in 2, cerebral infarct in 3, reoperation due to bleeding in 1, mediastinitis in 1, and low cardiac output syndrome necessitating IABP in 3 patients. Complicatons related to harvesting of the arterial grafts were not experienced in any of the patients. Conclusion: The results of the current data show that utilization of the RGEA in CABG is not associated with increased mortality/morbidity and demonstrates satisfactory short term results suggesting the usefulnessof this conduit as an arterial graft.

      • KCI등재

        The Unique Relationship between Neuro-Critical Care and Critical Illness-Related Corticosteroid Insufficiency : Implications for Neurosurgeons in Neuro-Critical Care

        Yoon Hee Choo,Moinay Kim,Jae Hyun Kim,Hanwool Jeon,Hee-Won Jung,Eun Jin Ha,Jiwoong Oh,Youngbo Shim,Seung Bin Kim,Han-Gil Jung,So Hee Park,Jung Ook Kim,Junhyung Kim,Hyeseon Kim,Seungjoo Lee 대한신경외과학회 2023 Journal of Korean neurosurgical society Vol.66 No.6

        The brain houses vital hormonal regulatory structures such as the hypothalamus and pituitary gland, which may confer unique susceptibilities to critical illness-related corticosteroid insufficiency (CIRCI) in patients with neurological disorders. In addition, the frequent use of steroids for therapeutic purposes in various neurological conditions may lead to the development of steroid insufficiency. This abstract aims to highlight the significance of understanding these relationships in the context of patient care and management for physicians. Neurological disorders may predispose patients to CIRCI due to the role of the brain in hormonal regulation. Early recognition of CIRCI in the context of neurological diseases is essential to ensure prompt and appropriate intervention. Moreover, the frequent use of steroids for treating neurological conditions can contribute to the development of steroid insufficiency, further complicating the clinical picture. Physicians must be aware of these unique interactions and be prepared to evaluate and manage patients with CIRCI and steroid insufficiency in the context of neurological disorders. This includes timely diagnosis, appropriate steroid administration, and careful monitoring for potential adverse effects. A comprehensive understanding of the interplay between neurological disease, CIRCI, and steroid insufficiency is critical for optimizing patient care and outcomes in this complex patient population.

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