韓國人의 各 臟器組織中 靑酸鹽의 微量分布에 關한 硏究(Ⅱ)

張成吉,金恩浩,金英雲,李鎭勳,柳在薰,權五星,金明德,吳世珍,金由那 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

Mycobacterium intracellulare에 의한 요추부 척추염 1예

장은영,김미영,김정욱,송은희,백관미,정용필,성흥섭,김미나,김양수,우준희,이상호 대한감염학회 2007 감염과 화학요법 Vol.39 No.3

비결핵성 미코박테리아에 의한 척추염에 대한 증례 보고가 국내에서는 아직 없었다. 저자들은 기저질환이 없는 환자에서 M. intracellulare에 의한 척추염을 rpoB 유전자에 대한 PCR-RFLP 방법을 통해 진단하였고 수술적 치료와 3제 병합 항균 요법으로 성공적인 임상 경과를 보인 1예를 경험하였기에 보고하는 바이다. We report a case of vertebral osteomyelitis due to Mycobacterium intracellulare in a 60-year-old man without predisposing conditions. He was successfully treated with surgical excision of the inflamed tissue and combined antimycobacterial therapy consisting of clarithromycin, ethambutol, and rifampin. In this case, polymerase chain reaction-restriction fragment length polymorphism analysis (PCR-RFLP) based on the rpo B gene of cultured isolates allowed rapid identification of M. intracellulare. Although very rare, nontuberculous mycobacteria (NTM) should be suspected as a causative pathogen of vertebral osteomyelitis. To the best of our knowledge, this is the first case of vertebral osteomyelitis caused by NTM reported in the Korean literature.

우리 나라 보건관리대행서비스 평가 연구

하은희,조수헌,김선민,주영수,한상환,하미나,권호장,홍윤철,김창엽 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.1

Group occupational health service programme started in 1990 is one of the measures to cope with limited human and financial resources in occupational health. The programme has expanded rapidly to include 52 institutions, private as well as public, all over the country. In spite of its potential impact on health of employees and practice of occupational health in small and medium sized industries, comprehensive evaluation in terms of quality has not been tried. This study has aims to develop the criteria to assess the quality of newly developed group occupational health service programme, and to investigate the quality of institutions, and finally to develop policies for the quality improvement. 1) Criteria development : By defining occupational health services, in particular for small and medium sized industries, as one of the primary health care, followings are included as core elements of qualitative occupational health programme; accessibility, continuity, comprehensiveness, technical quality, intersectoral collaboration, emphasis on preventive services, community participation, and adequacy. Again each element is divided into five major components of national health system infrastructure developed by the World Health Organization; development of health resources, organized arrangement of resources, delivery of health care, economic support, and management. In turn, each component is categorized into three aspects of quality assessment, structure, process and outcome. Expert panel selected several criteria for each category to evaluate the programme. Criteria were modified according to each group of interviewees, to produce two sets of questionnaire, one for chief operating officer and another for nurses in the institutions, and the chief operating officer and workers in the workplace. 2) Subject : Of all 52 institutions, 25 voluntarily participated in the survey. At individual institution, chief operating officer and practicing nurses were interviewed in depth. After intensive education for interviewees, every interviewees, every interview was performed with standardized guideline and questionnaire. The quality of the 'Group occupational health service programme' was found to be lower than expected. Especially in continuity, comprehensiveness, technical quality, community participation and adequacy, lower quality in structural aspect was commonly identified throughout all the institutions,. Quality in terms of accessibility and continuity highly varied among institutions., To improve quality of the programme, more comprehensive and systematic programme such as accreditation has to be introduced. In addition, human resources, governmental fund and information systems for individual workers are to be developed. As a long range plan, integration of occupational health services into the national health systems and pooling of financial resources and planned allocation should be considered.

프리셉터 경험이 간호업무수행과 직무만족에 미치는 영향 연구

류언나,송혜숙,장은희,서효신,추연화,김인선,나명주,지성애,박경숙 중앙대학교 간호과학연구소 2001 중앙간호논문집 Vol.5 No.2

The purpose of this study was to investigate how preceptor experience has an effect upon preceptor nurses. This study was so designed that it could compare the difference between clinical performance and Job satisfaction of preceptor nurses and those of nonpreceptor nurses. Study subjects were sampled out from those nurses who worked with two university hospitals where preceptor programs were implemented. The number of subjects totaled to 134, including 69 preceptor nurses and 70 nonpreceptor nurses. The score of preceptor nurses' clinical performance and job satisfaction revealed a higher value than that of nonpreceptor nurses. A similar result was also shown in the subdomains. However these difference were not statistically significant. Among all of the preceptor nurses, the highest number of preceptor experience was just one time. Except for five times in preceptor experience, the more the number of times of preceptor experience, the higher score in clinical performance. It was manifested that the number of preceptor experience was not related to job satisfaction. The score of preceptor nurses' clinica1 performance and job satisfaction revealed a higher value than that of nonpreceptor nurses. A similar result was also shown in the subdomains. However these difference were not statistically significant. The reward that preceptor nurses wished most was a reduction of the work load assigned to them. Currently preceptor nurses are only receiving a small quantity of financial reward related with their preceptor role. Most of preceptor nurses (96.8%) were not satisfied with their existing reward. Almost half of the preceptor nurses(43.5%) did not want to play a role as preceptor again. The reason why the scores of clinical performance and job satisfaction were low might be attributed to the inadequate preceptor training program and reward system. Appropriate knowledge and clinical skill are expected to enhance the level of preceptor nurses' clinical performance and appropriate internal and external reward to elevate the level of preceptor nurses' Job satisfaction. Therefore, it is needed for us to develop more effective preceptor education program, financial reward, support of colleague nurses and nursing managers, and adjust workload for the purpose of more effective preceptor programs.

전산유체역학을 이용한 싸이클론형 전기집진기 고도 설계 연구

이은주,장동순,나혜령,김혜숙 忠南大學校 環境問題硏究所 1995 環境硏究 Vol.13 No.-

A computer program is developed in order to figure out the physical insight of the combined dust removal equipment, that is, cyclonic electrostatic precipitator. The computer program employs Patankar's control-volume based finite-difference method, in which SIMPLEC algorithm is used for the resolution of pressure-linked momentum equation. Further two equation k-ε model is incorperated for Reynolds stresses and many empirical formulae are employed for dust charging and electric resistivity. A series of extensive parametric investigations are performed in terms of tangential velocity(swirl intensity), applied voltage across two electrodes, and particulate diameters, etc. It is found that the electrostatic force gives much more strong effect, expecially for small particulate, on the dust removal than the centrifugal force. Other calculated results are physically acceptable and consistent.

여성의 유방자가검진의 지식 정도

구한나,박인경,박하영,성초아,장다엘,홍은민 이화여자대학교 간호과학대학 2012 이화간호학회지 Vol.- No.46

Purpose: This study was to grasp women’s knowledge about Breast Self-examination. Methods: We collected data from 317 women who lives in certain city, Korea using structured questionnaire from 5th, August to 20th, September. The collected data was analyzed by SPSS 19.0. Results: The average score of women’ Breast Self-examination knowledge was 6.79±3.68 (of 17). There are three categories in knowledge about Breast Self-examination. Average score of category is 2.31 ± 0.71(of 4) for knowledge of breast cancer, 2.11 ± 0.57(of 5) for knowledge of breast cancer symptom, 2.37 ± 0.45(of 8) for knowledge of Breast Self-examination. Knowledge about Breast Self-examination according to general characteristics varied significantly for different age, marital status, education, and history of breast disease. Knowledge about Breast Self-examination according to characteristics related Breast examination was higher for women who received Breast Self-examination education, received Breast Self-examination education by lecture, performed Breast Self-examination, and who received Clinical Breast Examination Conclusion: People who are teenager and over sixties, their knowledge of Breast Self-examination was low. Therefore, effective Breast Self-examination education program should be provided for women who are teenager and over sixties to promote their Breast Self-examination practice regularly.

쪽파[Allium ascalonicum L.] 재배기간 중 Diazinon, Iprodione 및 Chlorfenapyr의 잔류랑 변화

고광용,나은식,김성헌,김상준,장영희,이규승 충남대학교 농업과학연구소 2005 농업과학연구 Vol.32 No.2

In order to know the residual pattern of pesticides and predict to the degradation period until below MRL, we experimented diazinon, iprodinon and chlorfenapyr for shallot. They were the most detected pesticide in shallot by NAQS (National Agricultural product Quality management Service) survey. In this experiment, we sprayed those pesticides 15days before harvest and analyzed 0, 1, 2, 3, 5, 7, 10, 14 day sample to establish logical equation and to calculate DT_(50). During the cultivating period, the residue amount of diazinon was changed from 1.02 mg/kg (0 day) to 0.01 mg/kg (14 day), DT_(50) was 2.19 days, and iprodione was changed from 1.45 mg/kg (0 day) to 0.14 mg/kg (14 day), DT_(50) was 4.15 days, and chlorfenapyr was changed from 1.5 mg/kg (0 day) to 0.01 mg/kg (14 day), DT_(50) was 1.97 days. The DT_(50) of double amount in those pesticides, diazinon was 2.24 days, iprodione was 4.82 days, and chlorfenapyr was 2.24 days, respectively.

일 도시 고등학생의 음주동기와 음주문제

강혜영,신경은,장현지,나영화,조은희 韓國學校保健學會 2004 韓國學校保健學會誌 Vol.17 No.2

Purpose : The purpose of this study was to investigate drinking motives and the drinking-related problems of Korean high school students at a city in Jeonbuk province. Methods : There were 657 students from two academic and two vocational high schools at J city in Jeonbuk province. The sample was collected using a stratified sampling method and the data was collected from June 30th to July 16th 2003. The study instrument used to examine drinking motive was a 20.item summated scale (Cronbach's α = .95) and for drinking-related problems was an 18 item summated scale (Cronbach's α = .91). The data was analyzed using SPSS/PC+ by percentage, χ2.test, t-test and correlations. Results : 1. Drinking experience: Among the high school students, 74.3% of them had drinking episodes. Female students started drinking later (χ2 = 12.857, p = .002) and had more drinking friends (χ2 = 7.785, p = .020) than males. Vocational school students drank more frequently (χ2 = 32.138, p = .001), had more heavy drinking episodes (χ2 = 40.370, p = .001). 2. Drinking motives & Drinking-related problems: The mean score of drinking motives was 31.2 ± 11.12 out of 80 and that of drinking-related problems was 21.8 ± 5.85 out of 72 points. Neither score were stronger was significantly different according to gender and grade. On the other hand, both drinking motives (t = .4.077, p = .001) and drinking-related problems (t = .3.423, p = .001) were stronger in vocational school students than in academic school students. The correlation between drinking-related characteristics and problems were weak (from r = .286 to r = .520) but the correlation within the subcategories of drinking motives was high such as between enhancement and coping (r = .822) and enhancement and social motives (r = .822). Conclusion : The majority of Korean high school students start to drink during their junior high school days. Drinking motives and drinking-related problems were not serious but the drinking motives and the drinking-related problems are stronger among vocational school students. As a result, school-based health education and counseling programs should focus on solving drinking motives than on drinking-related problems.

인체 자궁암 세포에서 천연 성분이 P-당단백질의 활성에 미치는 영향

정수연,고은정,김나형,성민경,장정옥,이화정 이화여자대학교 약학연구소 2005 藥學硏究論文集 Vol.- No.15

Multidrug resistance (MDR) of cancer cells is, at least in part, associated with the overexpression of P-gly-coprotein (P-gp). Many studies hve demonstrated that natural compounds obtained from fruits, vegetables, teas and medicinal plants may modulate P-gp activity. The objective of the present investigation was to examine the effect of seven natural compounds on the P-gp activity in human uterine sarcoma cell line, MES-SA/DX5. Daunomycin uptake was significantly increased by biochanin A and silymarin (p<0.0001) whereas it was reduced by morin (p<0.01). The efflux of daunomycin from the cells was significantly inhibited by biochanin A, morin, cephalotaxine, berberine (p<0.05) and silymarin (p<0.0001). Biochanin A, berberine and silymarin significantly decreased IC_(50) value of daunomycin (p<0.05) while morin increased it (p<0.05). These results suggest that some natural compounds such as biochanin A and silymarin may inhibit P-gp funciton and can by developed as MDR reversing agents to improve the efficacy of chemotherapeutic drugs when administered concomitantly.

대동맥 판막 치환술 후 반복되는 Acinetobacter baumannii 균혈증의 원인이 된 대동맥염 1예

정용필,김성철,송은희,장은영,김은경,김윤지,성흥섭,김미나,최상호,우준희,김양수 대한감염학회 2007 감염과 화학요법 Vol.39 No.3

감염성 대동맥염은 흔하지 않지만 매우 위중한 질병으로 Salmonella so.와 S. aureus가 주된 원인균이다. 아직까지 병원내 감염의 주요 원인균인 Acinetobacter baumannii에 의한 감염성 대동맥염은 보고된 바가 없었다. 저자들은 대동맥 판막 치환술을 시행받은 76세 남자 환자에서 적절한 항생제 투여에도 반복되는 A. baumannii 균혈증의 원인이 감염성 대동맥염으로 진단되었던 1예를 경험하였기에 보고하는 바이다. Infectious aortitis is an uncommon yet, life threatening disease. Early surgical treatment and prolonged antibiotic therapy is crucial to survival. Salmonella sp. and Staphylococcus aureus are the most common organisms isolated. There is no case report of infectious aortitis caused by Acinetobacter baumannii, which has recently emerged as a major cause of health care-associated infections. Here, we describe a 76-year-old male with infectious aortitis who experienced recurrent bacteremia due to A. baumannii in spite of adequate antimicrobial therapy after aortic valve replacement.