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( Judith Alvarez Otero ),( Lucia Gonzalez Gonzalez ),( Jose Luis Lamas Ferreiro ),( Alexandra Arca Blanco ),( Jose Ramon Bermudez Sanjurjo ),( Maria Rodriguez Conde ),( Javier De La Fuente Aguado ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: The aim of this study was to analyze the prevalence of carbapenem resistant Pseudomonas aeruginosa (CRPA) in urine cultures in our hospital. Moreover, we determined the mortality and risk factors associated to CRPA infection. Methods: Positive urine cultures to Pseudomonas aeruginosa between september 2012 and september 2013 were identified. We excluded repititive cultures from the same patient and episode. We created a database with demographic, clinical and laboratory items, including previous antibiotic therapy and antimicrobial resistance. Results: Forty-three cases with positive urine cultures to Pseudomonas aeruginosa were included. CRPA was observed in 12cases, with a prevalence of 27.9%. Sixty per cent were male with a median age of 73 years (range: 17-102). Sixty-seven per cent of patients were hospitalized when the culture was collected, but only 30% met criteria to nosocomial infection. Twenty-one percent of urine cultures corresponded to asymptomatic bacteriuria and 25% presented with sepsis. Mortality at 30 days was 20.7% in CRPA patients and 13.8% in the other group, without estatistical significance. Obesity (p =0.003), previous treatment with ciprofloxacin (p = 0.004) and quinolones in general (p = 0.001) and previous treatment with more than one antibiotic (p = 0.03) or with more than one family of antibiotics (p = 0.01) were risk factors to CRPA infection in the univariate analysis. Only obesity (p = 0.04) and previous treatment with ciprofloxacin (p = 0.02) showed statistically significant differences in the multivariate analysis, Conclusions: There is a high prevalence of CRPA in urine cultures in our population, wich is a potencial threat. We should assess the presence of risk factors for development of infections by such pathogen, as previous treatment with quinolones or obesity, in order to start appropiate empirical treatment in patients with severe urinary tract infections.
Impact of Cassia acutifolia Infusion on Glucose Levels in Obesity and Diabetes Rat Model
Raffoul-Orozco, Abdel Kerim,Avila-Gonzalez, Ana Elisa,Barajas-Vega, Jessica Lucia,Rodriguez-Razon, Christian Martin,Garcia-Cobian, Teresa Arcelia,Ramirez-Lizardo, Ernesto Javier,Rubio Arellano, Edy Da KOREAN PHARMACOPUNCTURE INSTITUTE 2017 Journal of pharmacopuncture Vol.20 No.3
Objectives: The aim of this study was to investigate the effects of Cassia acutifolia on the obesity and the glucose levels in a rat model of obesity and diabetes. Methods: By random selection, 36 Wistar male rats were divided in two control groups, the positive and the negative control groups, and into four experimental groups receiving different infusions of Cassia acutifolia in water ad libitum. Results: The results revealed a statistically significant anti-obesogenic effect (P = 0.02), although this was not considered clinically significant. Additionally, Cassia acutifolia lowered the glucose levels by 30 mg/dL to 90 mg/dL (P = 0.05). However, we observed adverse effects in the liver, a two-fold increase in transaminase levels (P = 0.002), and in the kidneys, decreased creatinine levels (P = 0.001), and these adverse effects had no viable explanation. Conclusion: Cassia acutifolia has anti-hyperglycemic effects in obese diabetic rats. However, Cassia acutifolia also has adverse effects, so it should not be administered to patients.
Design of Two-Stage Class AB CMOS Buffers: A Systematic Approach
Antonio Lopez Martin,Jose Maria Algueta Algueta,Lucia Acosta,Jaime Ramirez-Angulo,Ramon Gonzalez Carvajal 한국전자통신연구원 2011 ETRI Journal Vol.33 No.3
A systematic approach for the design of two-stage class AB CMOS unity-gain buffers is proposed. It is based on the inclusion of a class AB operation to class A Miller amplifier topologies in unity-gain negative feedback by a simple technique that does not modify quiescent currents, supply requirements, noise performance, or static power. Three design examples are fabricated in a 0.5 μm CMOS process. Measurement results show slew rate improvement factors of approximately 100 for the class AB buffers versus their class A counterparts for the same quiescent power consumption (< 200 μW).
Evaluation of Limestone -Based Remediation Technique in Sediments Affected by Mining Activities
Carmen Perez-Sirvent,M. Jose Martinez-Sanchez,M.luz Garcia-Lorenzo,Eva Gonzalez,Salvadora Martinez,Victor Perez,Lucia Martinez,Jose Molina,Carmen Hernandez,Jaume Bech,Manuel Hernandez-Cordoba 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6