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Diagnostic significance of diaphragmatic height index in traumatic diaphragmatic rupture
Junsik Kwon,John Cook-Jong Lee,Jonghwan Moon 대한외과학회 2019 Annals of Surgical Treatment and Research(ASRT) Vol.97 No.1
Purpose: Traumatic diaphragmatic rupture resulting from blunt trauma is usually severe. However, it is often overlooked during initial evaluation because there are no characteristic signs and symptoms. Thus, this study aimed to determine the clinical characteristics of diaphragmatic rupture caused by blunt trauma and investigate the diagnostic usefulness of diaphragmatic height index (DHI) measured using chest radiographs. Methods: The cohort comprised patients who were admitted due to diaphragmatic rupture from blunt trauma. Patients were divided into 2 groups; the control group comprised patients with blunt trauma who were matched for age, sex, and Injury Severity Score, while the DHI group comprised patients with diaphragmatic rupture from blunt trauma. Receiver operating characteristic curve was used to determine the cutoff value of DHI for diaphragmatic injury. The sensitivity, specificity, predictability, accuracy, and likelihood ratio of the cutoff were then determined. Results: A total of 60 patients were confirmed to have diaphragmatic rupture. The mean DHI in patients with diaphragmatic rupture on the right and left side were both significantly different compared to that in the control group. A DHI cutoff value of >1.31 showed 71% sensitivity and 87% specificity for diagnosing right diaphragmatic rupture, while a cutoff value of <0.43 showed 87% sensitivity and 76% specificity for diagnosing left diaphragmatic rupture. Conclusion: DHI can be useful in the diagnosis of diaphragmatic rupture. DHI as determined using chest radiographs in patients with blunt abdominal trauma, particularly in those ineligible for diagnostic work-up, may help in the diagnosis of diaphragmatic rupture.
National Follow-up Survey of Preventable Trauma Death Rate in Korea
Kwon Junsik,Lee Myeonggyun,Moon Jonghwan,Huh Yo,Song Seoyoung,Kim Sora,Lee Seung Joon,Lim Borami,Kim Hyo Jin,Kim Yoon,il Kim Hyung,Yun Jung-Ho,Yu Byungchul,Lee Gil Jae,Kim Jae Hun,Kim Oh Hyun,Choi Woo 대한의학회 2022 Journal of Korean medical science Vol.37 No.50
Background: The preventable trauma death rate survey is a basic tool for the quality management of trauma treatment because it is a method that can intuitively evaluate the level of national trauma treatment. We conducted this study as a national biennial follow-up survey project and report the results of the review of the 2019 trauma death data in Korea. Methods: From January 1, 2019 to December 31, 2019, of a total of 8,482 trauma deaths throughout the country, 1,692 were sampled from 279 emergency medical institutions in Korea. All cases were evaluated for preventability of death and opportunities for improvement using a multidisciplinary panel review approach. Results: The preventable trauma death rate was estimated to be 15.7%. Of these, 3.1% were judged definitive preventable deaths, and 12.7% were potentially preventable deaths. The odds ratio for preventable traumatic death was 2.56 times higher in transferred patients compared to that of patients who visited the final hospital directly. The group that died 1 hour after the accident had a statistically significantly higher probability of preventable death than that of the group that died within 1 hour after the accident. Conclusion: The preventable trauma death rate for trauma deaths in 2019 was 15.7%, which was 4.2%p lower than that in 2017. To improve the quality of trauma treatment, the transfer of severe trauma patients to trauma centers should be more focused.
Overexpression of p53, Mutation of hMLH1 and Microsatellite Instability in Gastric Carcinomas
Junsik Kwon,Ju-Hee Lee,Ye Seob Jee,Do-Jung Park,Hyung-Ho Kim,Hyuk-Joon Lee,Han-Kwang Yang,Kuhn Uk Lee,Hye Seung Lee 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.79 No.2
Purpose: Mutated p53 is a tumor suppressor gene, hMLH1 is a mismatch repair gene, and hypermethylation of hMLH1 follows microsatellite instability (MSI). This research’s aim is to investigate mutated p53, inactivated hMLH1 and MSI in gastric cancer and their clinicopathologic implications. Methods: Between 2003 and 2007, 618 patients underwent curative radical gastrectomy for gastric cancer at Seoul National University Bundang Hospital in Korea. We reviewed their medical charts and the pathologic reports with immunohistochemistry for p53, hMLH1 and polymerase chain reaction for MSI in 509, 499, and 561 cases, respectively. These genetic markers were statistically compared with clinicopathologic features and postoperative survival. Results: The expression ratios of mutated p53, inactivated hMLH1, and MSI were 32.8%, 8.4%, and 8.7%, respectively. Mutation of p53 occurred more frequently in aged group (over 40), differentiated group (against the non-differentiated group), intestinal type, infiltrative type and positive lymph node metastasis group. Inactivated hMLH1 occurred more frequently in aged group, differentiated group, intestinal type and expanding growth type group. MSI was found more frequently in aged group, intestinal type and expanding growth type group. All three genetic markers had no significant associations with the 5-year survival. Conclusion: We identified significant relationships between mutated p53, inactivated hMLH1, and MSI with some clinicopathologic features of gastric cancer. However, there were no apparent relationships between p53, hMLH1, and MSI and prognosis.
셀룰로오스 나노섬유의 첨가가 초소수성 실리카 나노입자의 분산 안정성 및 유변학적 특성에 미치는 영향
방준식 ( Junsik Bang ),김정규 ( Jungkyu Kim ),김윤진 ( Yunjin Kim ),황성욱 ( Sung-wook Hwang ),이태경 ( Taekyeong Lee ),안경선 ( Kyung-sun Ahn ),여환명 ( Hwanmyeong Yeo ),오정권 ( Jung-kwon Oh ),곽효원 ( Hyo Won Kwak ) 한국목재공학회 2021 한국목재공학회 학술발표논문집 Vol.2021 No.2
본 연구에서는 셀룰로오스 나노섬유를 증점제로 이용하여 초소수성 실리카 코팅용액을 제조하고자 하였다. 우선적으로 실리카 기반 소수성 코팅용액을 Tetraethyl orthosilicate (TEOS)와 Hexadecyltriethoxysilane (HDTMS)를 사용하여 sol-gel 공법으로 코팅용액을 제조하였다. 제조된 실리카 기반 코팅 용액을 건조 시킨 후 FT-IR로 이화학적 특성을 분석한 결과 실리카 나노입자가 HDTMS로 개질된 것을 확인할 수 있었으며, 투과전자 현미경을 통해 100 나노미터의 크기를 갖는 구형의 실리카 나노입자로 구성되어 있는 것을 확인하였다. 하지만 제조된 실리카 용액은 짧은 시간 내에 고형분이 침전되는 문제점을 가지고 있을뿐만 아니라 점도가 낮아서 코팅액으로 사용시에 균일한 코팅 공정을 구현하기가 어려웠다.. 이를 개선하기 위해 셀룰로오스 나노섬유를 증점제 및 분산 안정제로 첨가하였으며 레오미터를 통해 셀룰로오스 나노섬유의 함량에 따른 유변학적 특성을 평가하였다. 그 결과 셀룰로로오스 나노섬유는 분산 안정제 및 증점제의 역할을 하는 것을 확인할 수 있었으며 점도의 증가로 발림성 또한 증가하는 것을 볼 수 있었다. FT-IR 결과 및 투과전자 현미경 이미지를 통해 셀룰로오스 나노섬유 표면에 실리카 나노입자가 생성됨을 확인할 수 있었다. 추가적으로 셀룰로오스 나노섬유 첨가 비율을 최적화한 다음, 목재 표면에 코팅 한 결과 150도 이상의 높은 접촉각을 나타내는 것을 확인할 수 있었고, 낮은 sliding angle을 갖는 것을 통해 발수성 또한 갖는다는 것을 알 수 있었다.
스무딩 기반 그룹화 기법을 통한 G-PCC RAHT 화면 내 압축 성능 향상
권도완(Kwon, Dowan),이성배(Rhee, Seongbae),김준식(Kim, Junsik),김규헌(Kim, Kyuheon) 한국방송·미디어공학회 2023 한국방송공학회 학술발표대회 논문집 Vol.2023 No.11
3D 포인트 클라우드 데이터 압축을 위한 G-PCC(Geometry based Point Cloud Compression)의 속성 정보 부호화는 RAHT(Region Adaptive Hierarchical Transform)와 예측/리프팅 변환으로 이루어져 있다. 이 중, RAHT는 기존 Haar Transform이 2차원상에서 DC 계수 하나와 여러 개의 AC 계수로 변환하는 것과 달리, 3차원상에서 RAHT 단위 노드라는 새로운 단위를 바탕으로 고해상도에서 저해상도의 계층적 Haar 변환을 진행하는 방법을 나타낸다. RAHT가 수행된 후 출력된 AC계수들은 양자화가 진행한 후 엔트로피 부호화가 이루어지는데, 현재 RAHT를 수행한 콘텐츠의 고주파 영역 표현율에 비해 압축이 효율적으로 수행되지 않는다. 이에 본 논문에서는 AC 계수들의 엔트로피 부호화 효율을 증가시키기 위하여 그룹화 기법을 제안하고자 하며, 해당 그룹화 기법은 RAHT 단위 노드 내에 있는 점들의 점유 정보를 이용하여 같은 평면을 이루거나 같은 선분을 이루는 포인트들을 묶은 후, 각 포인트의 속성값에 스무딩을 진행함으로써 RAHT 변환 이후 출력되는 AC 계수들의 분산도를 줄이는 방법을 나타낸다. 또한, 본 논문에서는 실험을 통해 제안하는 그룹화 기법을 통하여 기존 RAHT 기술 대비 동일한 PSNR 값을 유지한 상태에서 속성 비트스트림 크기를 줄임으로써, 압축 성능이 향상될 수 있음을 검증하고자 한다.