경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염

홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

정신보건관련시설 입원(소)자의 주요 정신장애 유병률 : 전국 20개 시설의 입원(소)자를 대상으로

조성진,조맹제,서동우,함봉진,홍진표,배재남,이준영,이동우,박종익,전홍진,김성주,김용익 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.6

Objectives : One of the objectives of this study is to estimate the prevalence rates of psychiatric diagnoses in the combined populations of psychiatric hospitals, psychiatric nursing facilities and homeless asylums using the Korean version of the Composite International Diagnostic Interview (K-CIDI), which is a comprehensive and fully standardized interview schedule to assess psychiatric disorders for diagnosis. The Other objective is to compare with previously studied prevalence rates of Psy-chiatric diagnoses using the results of this study. Methods : The study subjects, aged from 181o 64 years, were randomly selected from 64,582 institutionalized population of psychiatric hospitals, Psychiatric nursing facilities and homeless asylums as of 30, June, 2001. Twelve trained interviewers administered the K-CIDI to the selected respondents. A total of 1,875 respondents (male 1,194, female 681) completed the interview. Results : The lifetime and one year prevalences of any diagnosis excluding nicotine dependence · withdrawal, anxiety disorder, eating disorder, somatoform disorder were 88.2% (male 88.1%, female 88.3%), and 65.8% (male 62.7%, female 73.7%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were 78.5% (male 75.3%, female 83.7%), and 56.8% (male 51.9%, female 64.8%), respectively. The lifetime and one year prevalences of alcohol use disorder (dependence/abuse) were 26.7% (male 37.9%, female 8.3%), and 8.7% (male 12.8%, female 2.1%), respectively. The lifetime and one year prevalences of mood disorder were 18.1% (male 13.5%, female 25.8%), and 10.4% (male 7.2%,female 16.9%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were comparable with the 2001 community survey by 1.19% to 1.32%, and 0.51% to 0.61%, respectively. The lifetime and one year prevalences of schizophrenia were also comparable by 0.16% to 0.28%, and 0.16% to 0.25%, respectively. There were no significant changes of prevalence rates when correction were applied to other psychiatric diagnosis. Conclusion : The results of this study could be used for evaluating the distribution of psychiatric diagnoses in mental health related facilities and for planning mental health policies.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

개발사업 환경성평가에서의 토양 탄소저장량 산정방법 비교 연구

황상일 ( Sang Il Hwang ),박선환 ( Sun Hwan Park ),전영봉 ( Young Bong Jeon ),황정배 ( Joung Bae Hwang ),강선홍 ( Seon Hong Kang ),김진홍 ( Jin Hong Kim ) 한국환경영향평가학회 2014 환경영향평가 Vol.23 No.6

The objective of this study was to propose the best methodology for estimating soil organic carbon stocks during environmental assessment for development projects. We compared three methodologies which were developed by Korea Environment Corporation(2010), Korea Forest Research Institute (2006), and Jin-Hyun Jung (1998). We found that the methodology developed by Jin-Hyun Jung (1998) shows the worst performance and the methodology of Korea Forest Research Institute (2006) does not reflect a variety of soil types and land use characteristics shown in development project plans. Therefore, we propose that the methodology developed by Korea Environment Corporation (2010) is the most reasonable one because it is internationally accepted and used for local governments to make the inventory of greenhouse gases as well as to set up its reduction strategy.

Cytokine and Tumor Environments

Jin Tae Hong1*, Ju Kyung Song, Sun Mi Kwon, Byung Woo Ahn, Youngsoo Kim, Sang Bae Han 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.1

Cytokines are known to function as regulatory molecules that can be produced by virtually every nucleated cell type in the body, including lymphocytes, monocytes/macrophages, epithelial cells, fibroblasts, and many others. Cytokines include lymphocyte-derived factors (lymphokines), monocyte-derived factors (monokines), hematopoietic factors (colony-stimulating factors), connective tissue/growth factors, and chemotactic chemokines. Cytokines released in response to infection can affect tumor development in different ways. When exposed to infectious agents, cytokines are secreted by sentinel cells, such as macrophages and dendritic cells. These cytokines include interleukin 1 (IL-1) and tumor necrosis factor-α, as well as others, such as IL-6, IL-12, and IL-18. When released in sufficient quantities, these molecules can cause inflammation. Chronic inflammation is highly associated with tumor initiation, promotion, and progression. In this article, we review the roles and mechanisms of cytokines in tumor development.

일반외과 영역에서 염증성 질환에 대한 Carumonam sodium의 임상효과 및 안전성 평가

배진선,신홍식 최신의학사 1993 最新醫學 Vol.36 No.4

이동통신 시장의 단말기 기반 경쟁 (DBC : Device Based Competition)이 경쟁과 소비자 후생에 미치는 영향분석 및 이동통신 서비스-단말기 결합분리(Decoupling) 유인을 통한 경쟁활성화 정책 매커니즘 고찰

홍진배 이화여자대학교 사회과학연구소 2014 사회과학연구논총 Vol.30 No.1

Mobile handset subsidy is one of three major competition tools together with tariff and quality of service. This has revealed ambidextrous aspects to the market competition and consumer surplus. While this provides basis for spreading mobile telecommunication service at the initial stage of the market, it becomes a controversial issue that excessive and discriminative handset subsidy may harm potential of the market growth and consumer surplus. Previous studies have mainly focused on how prohibition of handset subsidy affects consumer surplus and competition. However, this does not reflect complexity of shifting regulations and market situation that tightly couples handset and mobile services entering smart phone era since Nov 2009 in Korea. Thus, this research conducts interviews with various participants including MNOs, MVNOs, manufacturers, handset distributors, consumers and government officials in order to attain comprehensive understandings on changing dynamics of the mobile service and handset market. Based on empirical data, this study investigates relations among penetration rate of smart phone, No of number portability and fixed-mobile bundling services. This presents that changing competition in smart phone era reveals discontinuous change from previous competition in feature phone period acknowledging prominent role of handset subsidy in competition ahead of tariff and QoS. This study attempts to define this type of competition as ‘Device Based Competition (DBC)’ distinguishing from traditional competition concepts of facility based competition and service based competition. In this context, it analyzes DBC’s impact on mobile service and handset competition and consumer surplus. The results confirm that coupling mobile service and handset derived from unclear and discriminatory handset subsidy and its roller coasting may lead to ‘market failure’ in mobile service and handset market. Finally, this research suggests ‘policy mechanism’ for decoupling mobile service and handset, which result in promoting market price mechanism in each mobile service and handset industry and increasing consumer choice. 서비스 요금, 품질과 더불어 이동전화산업의 3대 경쟁수단중 하나인 단말기 보조금은 ‘양면성’을 가지고 있어서, 서비스와 단말기 시장의 초기시장 형성과 경쟁을 위한 기초를 제공하기도 하였지만, 포화된 시장에서의 불투명하고 과도한 보조금은 성장 잠재력 훼손과 소비자 후생에 부정적인 영향을 주기도 하였다. 그간의 연구들은 주로 피쳐폰 시대에 단말기 보조금의 금지여부에 따른 소비자 후생의 변화나 경쟁효과의 분석에 집중되어 있었다. 하지만, 2009년 11월부터 한국시장이 스마트폰 시대로 넘어 가면서 단말기 출고가, 이동전화 요금제 수준별로 단말기-서비스 번들링 등 단말기와 통신서비스의 관계가 변화되기 시작하였는데, 본 연구는 종전의 경쟁과는 단절적인 변화(Discontinuous Change)가 있음을 살펴보았다. 즉, ‘단말기’가 전통적인 통신서비스 경쟁수단인 ‘요금’과 ‘품질’ 보다 주된 경쟁수단으로 부상하였는데, 본 연구는 이러한 통신시장의 새로운 경쟁현상을 ‘단말기 기반 경쟁(Device Based Competition)’ 으로 규정하고, 이러한 경쟁이 MNO와 MVNO와의 경쟁, 단말기 제조시장의 경쟁, 소비자의 서비스와 단말기의 선택권 등 이동전화산업의 서비스-단말기 각 부문의 경쟁과 소비자 후생에 미치는 영향을 살펴보았다. 특히, 불투명한 단말기 보조금 지급으로 인한 이동전화 서비스와 단말기의 결합, 보조금 롤러코스터 현상이 소비자의 후생배분과 이동전화 서비스 및 단말기 유통시장에서 ‘시장실패’를 유발함을 확인하였다. 그리고, 이동전화 서비스와 단말기 유통 각각의 시장에서 경쟁을 촉진하기 위해 이동전화 단말기와 서비스가 불투명하게 결합된 구조를 분리하여 단말기와 서비스 각각의 ‘가격’의 작동을 정상화하고, 소비자가 서비스 가입시 단말기 보조금과 서비스 요금할인 중 선택할 수 있는 유인체계의 도입을 위한 ‘정책 매커니즘’을 제시하였다.

중증 만성정신질환자 수의 추산 : Through Two Community Surveys 두 지역사회 조사를 중심으로

홍진표,김윤,배재남,정유진,강영호,양병국,김용익,김병후,이철,조맹제 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.2

국내 중증 만성정신질환자 수를 추정하기 위하여 일 농촌 및 대도시 지역의 지역의료보험 및 의료보호 대상자 중 1993년 1년간 의료기관에서 정신증 상병(ICD-9 code 상 290-299) 및 알콜 남용/중독, 성격장애 및 정신박약 진단하에 치료를 받은 적이 있는 사람에 대해 설문조사를 실시하였다. 연구자들이 개발한 진단도구를 이용하여 진단을 평가하고, Strauss-Carpenter scale 등을 이용하여 기능 장애를 평가하고 유병기간 등을 조사하였다. 결과를 요약하면 다음과 같다. 1) 진단평가상 정신분열병군(61.1%)이 가장 많았으며, 정동장애군(23.7%), 알콜장애군(11.2%), 기질성 정신장애군(4.0%)의 순서이었다. 2) 직업활동정도는 진단군별로 차이가 많았다. 지난 1년간 직업활동이 6개월 미만이거나 전혀 없는 환자 비율이 정신분열병군은 67.2%, 알콜장애군 52.0%, 정동장애20.8%의 순으로 정신분열병군이 가장 불량하였다. 3) 사회활동도 진단군별로 차이가 많아서 지난 1년간 의도적, 사회활동이 없는 비율이 정신분열병군이 가장 높았고(72.3%), 알콜장애군(32.0%), 정동장애군(20.7%)의 순이었다. 4) 국내 의료보험 및 사회복지시설 이용 자료 등을 토대로 본 조사 결과를 적용한 결과 국내중증 만성 정신질환자의 수는 약 8만 7천명으로 추산되었다. Objectives: The purpose of this study was to estimate the number of serious and persistent mentally ill patients in Korea. Methods : Study populations were recruited from medical insurance data of two district areas ; one rural and the other urban areas. Subject were all mentally ill who had ever visited any hospital in 1993 and were diagnosed as having psychosis, personality disorder and drug abuse. We conducted a home visiting survey applying semi-structured diagnostic interview, assessing the level of social adjustment with Strauss-Carpenter Scale, and past psychiatric history by the trained researchers, in October and November,1994. Results : According to diagnostic assessment schizophrenic patients constituted the major portion(61.1%) of study subjects. The distribution of occupational functions and social contacts was variable according to diagnosis. Most schizophrenic patients were unemployed or worked less than 6 months in the previous year(67.2%), and showed poor social contact(72.3%). But affective disorder patients were relatively independent in job maintenance and social relationship. Alcoholic patients lay between those of schizophrenic and affective disorder groups. It was estimated that about 87,000 adult Koreans were suffering from chronic mental disorders which seriously interfere with their daily life. Conclusions : Serious and persistent mentally ill patients were common in Korea. Community support program should be provided for them.

김해시의 사용료 및 수수료 합리화 방안

홍완표,배진영 인제대학교 김해발전연구소 1997 김해발전연구 Vol.1 No.2

항암화학요법 치료시 환자에서 발생하는 오심 및 구토에서의 정맥주사용 및 경구용 Tropisetron의 제 4상 연구

배진선,김장용,장일성,윤완희,노승무,홍기훈 최신의학사 1997 最新醫學 Vol.40 No.7