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      • Direct Three-Dimensional Observation of Core/Shell-Structured Quantum Dots with a Composition-Competitive Gradient

        Chae, Byeong Gyu,Lee, Jun Ho,Park, Seongyong,Lee, Eunha,Kwak, Chang Min,Jafari, Majid,Jeong, Young Kyu,Park, Chan Gyung,Seol, Jae Bok American Chemical Society 2018 ACS NANO Vol.12 No.12

        <P>Synthesizing semiconductor nanoparticles through core/shell structuring is an effective strategy to promote the functional, physical, and kinetic performance of optoelectronic materials. However, elucidating the internal structure and related atomic distribution of core/shell structured quantum dots (QDs) in three dimensions, particularly at heterostructure interfaces, has been an overarching challenge. Herein, by applying complementary analytical techniques of electron microscopy and atom probe tomography, the dimensional, structural, topological, and compositional information on commercially available 11.8 nm-sized CdSSe/ZnS QDs were obtained. Systematic experiments at high resolution reveal the presence of a 1.8 nm-thick Cd<I><SUB><I>x</I></SUB></I>Zn<SUB>1</SUB><I><SUB>-<I>x</I></SUB></I>S inner shell with a composition gradient between the CdSe core and the ZnS outermost shell. More strikingly, the inner shell shows compositional variation because of competitive atomic configuration between Cd and ZnS, but it structurally retains a zinc-blende crystal structure with the core. The inner shell may grow through the decreased reactivity of S with Cd, followed by atomic diffusion-related processes. The composition-competitive gradient inner shell alleviates lattice misfit strain at heterostructure interfaces, thereby enhancing the quantum yield and photostabilty to a greater extent than those of other single-shell structures. Thus, this precise measurement approach could offer a potential pathway to develop a wide variety of three-dimensional core/shell-structured materials.</P> [FIG OMISSION]</BR>

      • KCI등재

        하지 심부정맥 혈전증의 장기 추적 보고

        소병준,변승재,채권묵,이경근,노병석,윤권하 대한혈관외과학회 2000 Vascular Specialist International Vol.16 No.1

        Purpose: Tn learn the long-term prognosis of patients with deep vein thrombosis (DVT), we evaluated the location and extent of thrombotic changes, hemodynamic status and clinical symptoms of patients of more than 12 months after development of acute thrombosis. Methods: 31 patients (man; 24, female; 7, mean age; 44.7:±13.2 years) with phlebograpically documented DVT were followed-up for 13-90 months (mean: 32.6±20.4 months) with Duplex scanning, and photo-plethysmography (PPG), and clinical symptorw. To evaluate the effects of treatment modality, the patients were devided into 3 groups; Group 1 (heparine+ warfarin, n=17), Group 2 (heparine+ warfarin+ catheter directed urokinase, n=10), Group 3 (heparine-twarfarin+systemic urokinase, n=4). But, the size of Group 3 was inappropriate to compare with other groups, we performed analysis of the results of Group 1 and 2. Results: Remained thrombi were detected in 22 patients (70.2%) of 31 patients by Duplex scanning, even 1 year later. Of the 29 patients studied with PPG, 24 patients (83%) revealed valvular incompetence in deep (11 cases, 38%) and superficial venous systems (13 cases, 45%). Thrombolytic rate in Group 2 was much higher than Group 1; complete resolution (40% vs 23%), complete obstruction (0% vs 41%). The statistically significant correlation between resolution degree and symptomatic improvement was shown (p=0.008). Conclusion: Residual thrombi and valvular damages after DVT were common, But, thrombolysis by catheter-directed urokinase may be associated with a higher rate of thrombolysis and clinical improvement. Anticoagulation alone may not be a sufficient method for treatment of DVT.

      • SCOPUSKCI등재

        성인형 여드름 환자의 사춘기 여드름 환자의 지질도 및 Propionibacterium acnes 수의 비교

        박연준,최성우,박현정,김형옥,채경옥,고재숙 대한피부과학회 2000 대한피부과학회지 Vol.38 No.9

        Background: Acne is principally a disorder of adolescence. However, a number of observational studies have documented a significant degree of acne in adult women. One study found a difference in women between late-onset acne and acne that persisted from adolescence. There were significant higher sebum excretion rates among women whose acne originated during the teenage years compared with late-onset acne groups. Objective: The purpose of this study was to examine the clinical features of patients with acne and to compare the sebum excretion rates and the density of P acnes in adult acne with that in adolescent acne. Methods: Thirty nine patients with acne vulgaris were clinically evaluated. Sebum secretion rates were evaluated by Sebutape method. The density of P acnes counted by scrub method. Results: 1. The severity grades were mild to moderate in adult acne groups, consisting with the lower acne lesion counts than that of adolescent acne groups. 2. Sebum secretion rates by Sebutape method showed different patterns in two groups. The mean value in the adult acne groups was lower than that in adolescent acne groups, but not statistically significant. Chin area dominant pattern, shown in adult acne groups, were not apparent in adolescent acne groups. 3. The density of P acnes was a lower mean value in the adult acne groups, but not statistically significant. Only in adolescent acne groups, the severity grades are well correlated to the density of P acnes. Conclusion: Adult acne was mild to moderate in severity. Clinically, adult acne differs from adolescent acne in that the lesions are located most commonly around the chin. Sebum excretion rate was the highest in the chin area of patients with adult acne. But there was no significant difference in two groups. Also the density of P acnes was not signiticantly different in two groups.

      • KCI등재SCOPUS

        류마티스 관절염의 관절액 Total Fibronectin의 임상적 의의

        김학준 ( Hak Jun Kim ),박정기 ( Jeong Ki Park ),여동근 ( Dong Geun Yoe ),윤원찬 ( Wern Chan Yoon ),정의달 ( Ye Dal Jung ),조선주 ( Sun Joo Cho ),김상경 ( Sang Gyung Kim ),전창호 ( Chang Ho Jeon ),김채기 ( Chae Ki Kim ),송용호 ( Yo 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.3

        Objective: A study on fibronectin, which is synthesized in response to inflammatory process of joint destruction, can be of great value in identifying the mechanism of inflammation or disease activity of rheumatoid arthritis (RA). This study attempts to measure the concentrations of total fibronectin in synovial fluid of patients with RA and osteoarthritis (OA), and compare it with the clinical disease activity parameters of RA available. Methods: A total 68 patients suffering from knee pain and joint effusion was examined. Synovial fluids of thirty-eight RA patients and thirty OA patients were measured by using monoclonal fibronectin antibody. Cross-sectional analysis was undertaken to correlate the fibronectin levels of the RA patients with the clinical disease activity parameters available. Results: 1. Mean synovial fibronectin level of RA (148.4±72.6㎍/ml) was significantly higher than that of OA (39.5±16.9㎍/ml)(p<0.001). 2. The fibronectin levels in RA do not seem to have significant relationship with the parameters such as disease duration, the duration of morning stiffness, Ritchie index, ESR, CRP, and rheumatoid factor. Conclusion: In conclusion, the synovial total fibronectin concentration can clearly distinguish RA from OA. However, it would be unlikely to be used as a parameter of disease activity.

      • KCI등재

        內障과 眼盲疾患의 韓方治驗에 關한 小考

        김경준,채병윤,Kim, Gyung-Jun,Chae, Bhung-Yoon 대한한방안이비인후피부과학회 1997 한방안이비인후피부과학회지 Vol.10 No.1

        The glaucoma, cataract and causing-blindness-diseases have high clinical importance by their severity of the symptoms and possibility of causing visual loss. Glaucoma is caused by an increase in the intraocular pressure, if severe enough, can cause field loss and eventually complete blindness. In cataract, the general clarity of vision is impaired due to a loss of transparency of the chrystalline lens of the eye. The causing-blindness-diseases can be divided to PokMaeng which cause sudden blindness and ChungMaeng, in which visual acuity is losed gradually. In glaucoma, cataract and causing-blindness-diseases, the visual acuity is affected and the patient may complain blurriness, fatigue of eye, visual field loss deficiency or scintillant feeling, vitreous floaters. In this study, 32 patients who have cataract, glaucoma or other causing-blindness-diseases was treated with oriental medicine or acupuncture from July, l996 to May. 1997, and was followed up by their symptoms and visual acuity. 1. In glaucoma patients, intraocular pressure decreased significantry and the symptoms improved positively. 2. In cataract patients, there was no improvement of visual acuity but $40\%$ of patients found their symptoms improved. 3. In causing-blindness-diseases, $57\%$ of patients reported improvement of their symptoms such as blurriness or fatigue of eye. 4. Through oriental medical treatment, the symptoms of glaucoma, cataract and causing-blindness-diseases can be treated effectively. Therefore oriental management seems to be possible to cure glaucoma, cataract and causing-blindness-diseases.

      • KCI등재

        中醫皮膚疾患의 現況과 處置에 對한 分析

        김경준,채병윤,Kim, Gyung-Jun,Chae, Byung-Yoon 대한한방안이비인후피부과학회 1996 한방안이비인후피부과학회지 Vol.9 No.1

        The study was clinically performed with the 128 out patients of dermatic disease who had visited the Dept. of dermatology, Dongzhimen Hospital, Beijing traditional medical college from May 2nd to February 14th 1996. The results were as follows. 1. The dermatologic findings which showed higher incidence in this study were Acne of Melasma 27 cases($21.0\%$), Psoriasis 25($19.5\%$), Eczema including Contact dermatitis 21($16.4\%$), Seborrheic dermatitis including Alopecia of hair 12($9.3\%$) and Urticaria 11($8.5\%$). 2. The sex ratio of male to female was 4.5 : 5.5. The peak incidence of age group was 30-39($21.8\%$). 3. In the duration of disease, 37 cases($28.9\%$) were between 1 year and 5 years. 27($21.1\%$) were over 10 years. 4. About the single herb drugs, they are Angelicas gigantis Radix, Paeoniae Radix and Salviae Radix in order of frequencies. In the case of pill type, Danggui gosam hwan. Chunggan hwan. Whaeo hwan and Shinnongjiyang hwan are most frequently used. In the case of topica, Whangyeongo, Juachanggo and Soeungo are used in high frequencies. 5. For the test and surgical treatment KOH surgical treatment of Molluscum contagiosum in 8 cases and the bloody treatment of Chronic psoriasis in 3 cases.

      • KCI등재

        桂枝湯 加味方의 알레르기 鼻炎에 對한 治驗報告

        김경준,채병윤,Kim, Gyung-Jun,Chae, Bhung-Yoon 대한한방안이비인후피부과학회 1997 한방안이비인후피부과학회지 Vol.10 No.1

        This study evaluates the effect of G.G.(桂枝湯 加味方) in patients with allergic rhinitis which deteriorates with cold, who visited Oriental hospital of Kyungwon University from march to september in 1996 and found the symptoms were inproved significantly. 1. G.G.(桂枝湯 加味方) was prescribed for the patients with sneezing and more than $80\%$ of patients showed improvement 2. Oriental treatments of allergic rhinitis have been showed relative good results and more constructive study and clinical report are necessary.

      • KCI등재

        回春凉膈散이 抗알레르기 및 消炎, 鎭痛, 解熱效果에 미치는 影響

        김경준,김중호,채병윤,Kim Gyung Jun,Kim Joong Ho,Chae Byung Yoon 대한한방안이비인후피부과학회 1994 한방안이비인후피부과학회지 Vol.7 No.1

        The Effects of Hoichunyanggyuksan on the Anti-allergic Effect, Analgesic Action, Anti-inflammatory Action and Antipyretic Action. Experimental studies were done to research the clinical effects of Hoichunyanggyuksan on the Anti-allergic effect, Analgesic action, Anti-inflammatory action and Antipyretic action. The results obtained as follows; 1. On vascular permeability responses to intradermal histamine, Hoichnyanggyuksan showed significant effect. 2. In the homologous PCA provoked by the IgE-like antibody against white egg albumin, Hoichunyanggyuksan showed the decreasing tendency, but was none significant effect. 3. In the delayed type hypersensitivity responses to Picryl chloride, Hoichunyanggyuksan was proved significant effect. 4. In the delayed type hypersensitivity resposes to SRBC, Hoichunyanggyuksan revealed significant effect. 5. In Anti-pyretic action by yeast method, Hoichunyanggyuksan showed significant effect. 6. In Anti-inflammatory action by carrageenin method, Hoichunyanggyuksan showed significant effect. 7. In analgesic action by acetic acid method, Hoichunyanggyuksan was recognized significantly.

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