Removal of Serratia marcescens Aerosols Using an Electrostatic Precipitator Air-Cleaner

( Gwang Pyo Ko ),( Harriet Burge ) 한국미생물생명공학회 2007 Journal of microbiology and biotechnology Vol.17 No.10

Host genetics, microbiota, metabolic syndromes and beyond

Gwang Pyo Ko 한국실험동물학회 2018 한국실험동물학회 학술발표대회 논문집 Vol.2018 No.7

Gut microbiota, metabolites and liver diseases

고광표 ( Gwang Pyo Ko ) 대한간학회 2019 간학회 싱글토픽 심포지움 Vol.2019 No.1

Session 2: 위장관 바이러스성 질환의 국내 역학 및 특성 : 노로바이러스 제어법 및 관리 동향

고광표 ( Gwang Pyo Ko ) 대한인수공통전염병학회 2013 창립총회 및 학술대회 초록집 Vol.2013 No.1

A Study on the Structure Analysis of Skate for Transportation Using Composite Materials

Ko, Sun Ho,Kim, Hong Gun,Shin, Hee Jae,Kim, Hyun Woo,Cha, Yun Ju,Cha, In Pyo,Kim, Gwang Cheol,Kwac, Lee Ku Trans Tech Publications, Ltd. 2014 Advanced materials research Vol.939 No.-

<P>As society became more complex, the logistics also increased, demanding for logistics transport vehicles and feeder has increased. Because the self-weight of skate for cargo transport used in this study is heavy, it needs to be weight lightening. However there is a lack of capital and technology not to improve lasting. We conducted FEM studies about weight lightening applying composites on cargo transport skate and the stiffness can be obtained at the same time. However, due to the presence of discontinuities such as holes in the parts. If you are applying composite, Because this causes the degradation of the strength of the material under static and fatigue load induced stress concentration in parts. In order to examine the safety of the cargo transport skate, you must consider the impact of the static strength damage on the stress concentration because of the discontinuous parts. In this study, therefore, the cargo skate was performed to evaluate the structural analysis through the FEM analysis. As a result, it was found that CFRP compared to existing SM45C is superior 25% when considering the characteristics. It indicated the best results in about 30% of the weight lightening.</P>

국내 유통 중인 환약의 미생물 검출수준

고광표,신헌태,Ko, Gwang-Pyo,Shin, Heon-Tae 대한예방한의학회 2011 대한예방한의학회지 Vol.15 No.3

1. 서울, 경기소재 한의원에서 환약 10종과 경기소재 약국1곳에서 판매되는 한방환약 10종, 총 20종의 환약에 대해 미생물검출연구를 하였다. 2. 총세균수는 한의원환약, 약국환약에서 모두 WHO기준(1.0${\times}$107) 이내로 검출되었다. 3. 총진균수는 한의원환약, 약국환약의 각각 2종류, 1개제품에서 WHO기준(1.0${\times}$104)을 초과 하였다. 4. 배양 비의존적 방법을 이용하여 환약에 분포하는 Bacteria를 동정한 결과, 대부분의 박테리아는 토양에 존재하는 Firmicutes문, Proteobacteria문의 두 종류에 속하였다. 5. 환약의 안전성을 제고하기 위해, 생산, 가공, 유통, 보관 등 각 단계에서의 추가적인 미생물검출연구가 필요하다. Objectives : This study has aimed to monitor microbial detection on pill types of herbal medicine which are circulating in markets including Oriental Medical Clinics(O.M.C.s) and Pharmacy in Korea. Methods : 10 different samples of O.M.Cs and 10 different samples of Pharmacy were investigated by culture method and non-culture method based on the 9th edition of microbial examination released by Korea Food & Drug Administration. Results : The total microbial count among each 10 samples were detected within the limit suggested by WHO. 2 samples of O.M.C.s and 1 samples of Pharmacy exceeded WHO's limit in fungi count. No samples exceeded WHO's limit in bacteria count. Most bacteria founded in samples were the phylum of Firmicutes and Proteobacteria which are common in soil by non-culture method. Conclusion : Further study should be followed to set up proper microbial limit of herbal materials including pill types.

주물사 재생 유동층내 폐열회수 증진에 관한 실험적 연구

백고길(Baek Ko-Kil),박종순(Park Jong-Suen),이은표(Lee Eun-Pyo),최승일(Choi Sung-Ill),최국광(Choi Guk-Gwang),전성택(Jeon Sung-Taek) 한국태양에너지학회 1998 한국태양에너지학회 논문집 Vol.18 No.2

본 연구는 furan 주물사의 재생시 냉각효율을 크게 높으며 폐열의 회수를 증진하는 데 활용 할 수 있는 자료들을 얻기 위하여, 재생된 Furan foundry sand를 유동입자로 사용한 유동층에서 평활관(smooth tube), 나선관(spiral tube) 및 핀관(finned tube)을 수평으로 설치하여, 유동층내 온도를 50~200℃로 유지하면서 전열관에 대한 열 전달계수를 실험적으로 구하였다.<br/> 유동층의 내경은 210mm이고, 전열관의 외경은 모두 12.7mm인 동관을 각각 사용하였다. 본 실험은 관내 냉각수의 Reynolds수 4,000~18,000범위이고, 유동층내 유동입자 Reynolds수 0.8~7.5의 범위에서 수행하여 다음과 같은 결과들을 얻었다.<br/> 1. 유동층내 온도가 높으면 모든 전열관에서 열 전달계수는 커진다.<br/> 2. 최대 열 전달계수는 평활관에서는 Re_p수 3.5~5.5, 나선관에서는 Re_p수 4.4~5.2, 핀관에서는 Re_p수 3.5~4.8의 범위에서 각각 얻을 수 있다.<br/> 3. 유동층내의 온도에 따라 약간 다르지만 평활관, 나선관 및 핀관에서의 최대 Nu수들은 각각 대량 1:1.5:3.0의 비를 얻는다. In this experimental study, for obtaining the data to be used in the increased recover rate of waste heat from the recirculated sand, the furan foundry sand were used as the fluidized particle in the fluidized bed in which the smooth, spiral and finned tubes (Do= ??12.7) were horizontally installed and used as the heat-transfer tubes.<br/> The heat transfer experiments were performed in the conditions of water Reynolds number of inside tubes in the range of 4,000 to 18,000 and particle Reynolds number of outside tube in the range of 0.8 to 7.5.<br/> The heat-transfer coefficients (ho) increase as the higher inside temperature of the fluidized bed and the maximum heat-transfer coefficients can be obtained in the range of 3.5 to 5.5 of particle Reynolds number in the all tubes. The maximum Nu numbers of smooth, spiral and finned tubes are figured as about 1:1.5:3 in order even if the ratios show little different as the temperatures of bed.

The Korean Society of Gastroenterology & SIDDS 2045 : Slide Session ;K-LG-16 : Lower GI Tract ; Therapeutic Effect of Human Placenta and Adipose- Dirived Mesenchymal Stem Cells on Radiation Proctitis Rat Model

( Won Hee Kim ),( Sung Pyo Hong ),( Chang Il Kwon ),( Kwang Hyun Ko ),( Pil Won Park ),( Ki Baik Hahm ),( Gwang Il Kim ),( Sei Kyung Chang ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

Background: Radiation proctitis is a common complication of radiation to lower abdomen and pelvis. Different modalities of treatment are available, however the effi cacy is incomplete. We hypothesized that human placenta and adipose-derived mesenchymal stem cells could have therapeutic potential on radiation proctitis. Methods: Placenta and adipose-derived mesenchymal stem cells were locally injected on distal rectal mucosa of female Sprague-Dawley rats within 24hrs of 25Gy rectal irradiation. 1,2,4 weeks later, they were sacrifi ced and the rectum was removed and blood sample was obtained to evaluate various parameters of infi ammation Results: Transplanted stem cell was identifi ed at rectal mucosa during 4 weeks after irradiation. Severe proctitis was provoked after pelvic irradiation refi ected with extensive infi ammatory cell infi ltration, loss of crypt epithelium and collagen deposition. However, treatment with mesenchymal stem cell restored these pathologic indices. In addition, mesenchymal stem cell had anti-infiammatory effect, anti- apoptotic effect. Regenerative property were increased. These effect was more prominent on adipose-derived mesenchymal stem cell. Conclusions: Placenta and adipose derived mesenchymal stem cell transplantation may be an potential therapeutic strategy to treatment of radiation proctitis.

UV air disinfection respiratory viral aerosols

Christopher Walker,고광표(Gwang Pyo Ko) 대한환경공학회 2006 대한환경공학회 학술발표논문집 Vol.2006 No.12

Ultraviolet (UV) air disinfection is one of the engineering control methods utilized to control airborne transmission of pathogenic microorganisms in high risk settings. However, despite the recent emergence of respiratory viral pathogens such as SARS coronavirus and avian influenza viruses, UV air disinfection of viral aerosols is poorly studied. Hence, we characterized UV disinfection of viral aerosols using MS2, adenovirus, and coronavirus. The objectives of this study are (1) characterize the effect of nebulization and air sampling on the survival of tested viruses; (2) quantitatively estimate UV susceptibilities of these viral aerosols; (3) evaluate the effect of relative humidity (RH) on the susceptibility of viral aerosols to UV irradiation. A bench-size experimental chamber was built and evaluated for this study. MS2, adenovirus, or coronavirus was aerosolized into the experimental chamber, exposed to different UV doses, at either 50% or 75-80% RHs, and then sampled by AGI-30 liquid impinger at 12.5 LPM. The collected samples were analyzed by plaque assays to measure the UV susceptibilities of tested viral aerosols. Our data indicated that neither nebulization nor air sampling using liquid impinger caused significant inactivation of non-enveloped viruses such as MS2 or adenovirus. However, coronavirus was significantly inactivated by both nebulization and air sampling. Both MS2 and adenoviruses were very resistant to UV air disinfection. Less than 1 log reduction in viable virus was observed at the 2.6 mJ/㎠ UV dose for both viruses. However, coronavirus was more susceptible to UV air disinfection, which suggests that UV air disinfection could be an efficient environmental control method to prevent airborne transmission of novel SARS coronavirus. There was no significant protective effect of high RH on UV susceptibilities of the tested viral aerosols. Finally, our study also confirmed that UV disinfection rates of viral aerosols are much different from those of viruses suspended in water.

자외선 조사와 은나노입자 조합을 통한 바이러스 저감 효과에 관한 연구

정해용(Hae-Yong Jung),고광표(Gwang-Pyo Ko) 서울대학교 보건환경연구소 2017 보건학논집 Vol.54 No.1

Objectives: The purpose of this study is to evaluate the antiviral capacity of the combinations Ultraviolet –A (320 –400 nm) or –B (280 –320 nm) (UV –A or –B) and silver nanoparticles (AgNPs). Methods: Combined antiviral effects of ultraviolet-A or –B and AgNPs were tested by plaque assay. Various combinations of UV-A or -B and AgNPs were exposed to tested viruses. Murine norovirus (MNV) and mouse hepatitis virus (MHV) were used as surrogates of human norovirus, known as a causing of viral gastroenteritis in humans and coronavirus, known as a cause of respiratory diseases in humans, respectively. Results: AgNPs size, concentration and UV kind influenced antiviral capacity. MNV were more susceptive to AgNPs than MHV (p〈0.05) while MHV were more susceptive to UV-B (p〈0.05). Specially, the combinations of UV-B and 10 nm size (1 ppm or 10 ppm) AgNPs were more effective than UV-B treatment only (p〈0.05). Conclusion: These results suggest that combined antiviral effects of UV-B and AgNPs could be applied in disinfection processes for pathogenic viruses under various environmental conditions.