서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

플라보노이드의 세포 신호전달 조절

이응룡,강근호,강용진,김우열,최혜연,김봉우,정효순,조쌍구 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

Many studies revealed the neuroprotective, cardioprotective, and chemopreventive actions of dietary flavonoids. The plausible mechanistic interpretation of the various effects of flavonoids was concentrated on the anti-oxidant or free radical-scavenging properties of these phytochernicals, both in model systems and under in vivo conditions. While there has been a major focus on the anti-oxidant properties. there is an emerging view that flavonoids and their in vivo metabolites. do not act as conventional hydrogen-donating anti-oxidants. but they may exert regulatory functions in cells through actions at protein kinase or lipid kinase signaling pathways. Flavonoids and more recently their metabolites. have been reported to act at phosphoinositide 3-kinase(PI 3-kinase). Akt/protein kinase B(Akt/PKB), protein kinase C (PKC), mitogen activated protein kinase(MAP kinase), and various tyrosine kinases signaling cascades. Inhibitory or stimulatory actions at these pathways are likely to affect cellular function profoundly by altering the phosphorylation state of target molecules and by modulating gene expression. A clear understanding of the mechanisms of action of flavonoids, either as anti-oxidants or modulators of cellular signaling pathways, and the influence of their metabolism on these properties are key to the evaluation of these potent biomolecules as anti-cancer agents, cardio-protectants, and inhibitors of neurodegeneration.

후두결핵의 임상적 고찰

이동건,심우영,조재민,박현민,이진춘,왕수건 釜算慶南耳鼻咽喉科學會 1996 임상이비인후과 Vol.7 No.2

等電點 電氣泳動에 의한 배추와 양배추 育成系統에서의 自家不和合性 關聯 glycoproteins의 比較分析

이정명,최근원,민병훈,이태진,백남권,이철우 경희대학교 부설 식량자원개발연구소 1994 硏究論文集 Vol.15 No.-

等電點 電氣泳動을 이용하여 배추의 몇 개의 5-allele 造成과 그들의 F₁에서 自家不和合性의 발현과 관련된 glycoprotein의 band 樣相을 비교 분석한 결과는 다음과 같다. 1. 배추의 內婚系와 이들 간의 에서 柱頭內 glycoprotein의 band pattern을 分析한 결과 兩親의 band pattern이 F₁으로 그대로 遺傳되므로 써 명확한 同定 및 區分이 가능하였다. 2. 공시된 배추의 계통 중에서 8개의 等電點을 발견하였는데 대부분의 系統에서 pl 7.0 또는 8.6에서 major band를 보이고 있었다. 따라서 major band만으로는 S-allele genotype의 명확한 동정이 불가능한 경우도 상당히 있었다. 3. 상기 bands (pI 6.8 and 7.7)에서의 glycoprotein의 分子量은 pI 7.0에서 49,000-50,000이었고 pI 8.6에서 59,000으로 推定되었다. 4. 양배추는 배추에 비해서 glycoprotein의 major bands와 minor bands수가 많고 매우 다양하게 나타나므로써 S-allele 동정이 배추보다 매우 용이할 것임을 보여 주었다. Band patterns of glycoproteins associated with the expression of self-incompatibility were examined in the stigmatic extracts of self-incompatible Chinese cabbage inbred lines and the hybrids. Clear relationship in the band pattern could be confirmed in the parents and their hybrid, indicating the inheritance of S-alleles to the progeny. Total of 8 isoelectric points were indentified in the inbreds, with the major bands at pI 7.0 and 8.6. Thereforne, in some genotypes, identification of cultivars or S-allele genotypes were impossible with the major bands only. The molecular weights of the glycoproteins were estimated to be 49,000-50,000 for pI 7.0 and 59,000 for pI 8.6 bands. The stigmatic extracts from cabbages showed numerous major and minor bands so that identification of S-allele genotype will be much easier as compared to chinese cabbage.

아담·스미드 時代의 思想에 관한 小考

李瑾雨 진주교육대학교 1983 論文集 Vol.27 No.1

인체 Calbindin-D9k 항체 제작과 종특이적 활성

이근우, 홍의주, 이근식, Vu-Hoang Dang, 정의배 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.2

본문참고

Poplar 組織培養에 의한 anthocyanin 生成

李承雨,崔根元,鄭印植 경희대학교 유전공학연구소 1993 遺傳工學論文集 Vol.5 No.-

Poplar(Populus nigra)를 대상으로 組織培養時 callus 生長과 anthocyanin形成에 影響을 미치는 環境條件으로써 最適培地, 糖의 效果, 植物生長調節劑, 糖의 種類 및 日長의 影響을 검토하고자 遂行한 결과는 다음과 같이 요약된다. 1. SH 培地가 callus 및 anthocyanin형성에 효과적이었고 sucrose濃度는 5.5%가 우수하였다. 2. Auxin류의 효과에 있어서는 2,4-D 2.0 ㎎/ℓ에서 callus 및 anthocyanin형성에 가장 효과적 이었다. 3. Cytokinin류에서 BA가 kinetin에 비하여 callus生育을 顯著하게 抑制하였고 kinetin 0.2㎎/ℓ에서 anthocyanin형성이 가장 우수하였다. 4. 糖의 종류로는 fructose가 sucrose나 glucose에 비하여 callus增殖에 월등히 높은 효과를 보였고 anthocyanin形成量에는 큰 차이를 보이지 않았다. 5. 日長의 效果에서 anthocyanin形成은 日長이 길어질수록 促進되었으며 callus형성은 日長에 따른 차이를 보이지 않았다. The experiments were conducted to optimize culture conditions for callus growth and anthocyanin formation by in vitro culture of Populus nigra through tests of basal media, inorganic salts, plant growth regulators, sucrose concentrations, sugar and photoperiods. SH media supplemented with 55 g/l sucrose gave the best results in callus and anthocyanin formation. For the effects of plant growth regulators, anthocyanin formation was promoted by treatment with 2.0 ㎎/l 2,4-D. On the other hand, 0.2 ㎎/l kinetin showed the highest activity for anthocyanin synthesis while BA severely suppressed callus growth. Fructose compared with glucose remarkably promoted callus growth but anthocyanin formation showed no difference with sugar type. Anthocyanin pigment accumulation hastened by increasing photoperiod in culture room while callus growth was not affected with photoperiod.

아담·스미드 時代의 스코틀랜드 思想에 관한 硏究

李瑾雨 진주교육대학교 1984 論文集 Vol.28 No.1

수치지형도를 활용한 홍수지도 제작용 지형자료의 효과적인 구축방법 연구

이근상,고덕구,김우구 한국지리정보학회 2004 한국지리정보학회지 Vol.7 No.1

한국수자원공사에서는 홍수지도 제작을 위한 정밀 지형자료 구축을 위해 LiDAR 측량을 실시하고 있으며, 향후 전국에 대한 홍수지도 제작시 막대한 비용이 소요될 것으로 예상된다. 따라서 홍수지도 제작이 꼭 필요한 지역을 선정하기 위한 사전모의용 자료구축을 위해 NGIS 수치지형도를 활용하는 것이 바람직하며, 이를 위해서는 각 축척별 수치지형도의 표고오차 분석이 필요하다. 본 연구에서는 수치지형도의 DEM 오차를 평가하기 위해 LiDAR 측량을 수행하여 구축한 DEM과 비교하였다. 특히 수치지형도로부터 구축한 TIN으로부터 DEM을 생성하기 위해 수행하는 보간법의 종류에 따라 발생하는 오차특성을 분석하였다. 분석결과 1:1,000 수치지형도가 1:5,000 수치지형도에 비해 오차가 작게 나타났으며, linear 보간을 수행한 DEM이 quintic 보간을 수행한 DEM에 비해 작은 오차특성을 보였다. 특히 도시지역의 경우 완만한 경사로 구성되어 있기 때문에 해상도에 따른 DEM 오차의 변화는 매우 작은 것으로 평가되었다. Korea Water Resources Corporation carried out LiDAR survey to construct detailed terrain data for flood mapping and it is expected that much money is required in flood mapping of all over the country. Therefore, it is desirable to use NIS digital map to construct preliminary modelling data for selection of flood mapping area. And the analysis of DEM error with respect to scale of digital map is necessary for the sake of applying digital map as the input data of flood mapping. We compared DEM from digital map with DEM from LiDAR survey. Especially we analyzed DEM error characteristics that is occurred with respect to the interpolation method that is used to construct DEM from TIN of digital map. As a result of analysis, digital map(1:1,000) showed smaller error than digital map(1:5,000) and DEM applying linear interpolation showed smaller error than DEM applying quintic interpolation. Especially, variation of DEM error by cell resolution was evaluated as very slight because urban district was composed of gentle slope.

주행로봇의 경로제어

이우송,오세봉,안용근,한성현 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

This paper propose a new path planning method for mobile robots. The creation method of the course approaches with the method of the frame line graph base where the calculation time becomes disturbance. The graph composition where is not the static course plan method of existing, a course search and repeats continuously changes a graph and proposes the course the dynamic routing plan method. The method which is proposed is composed of a course creation phase and a course improvement phase, each phase includes a graph composition and a course search process.