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      • KCI등재

        자폐아동의 기본운동교육프로그램 참가가 지각운동능력발달에 미치는 영향

        이창섭,이명휘,현광석,이창규,조병준 한국특수체육학회 2003 한국특수체육학회지 Vol.11 No.1

        The purpose of this study was to examine how the program of basic movement can influence and change the capability of perceptive movement among the children with autism. Four subjects (age3-5) participated in the specially designed program, three times a week for four weeks. For the purpose of this study, Oseretsky's Motor Development Test and PMDT(perception-Movement development Diagnosis Test) were used. The results were as follows; First, the upper limb performance of the children with autism showed significant changes by the movement education program. Second, along with the development of upper limb performance, the motor development index of the children with autism showed significant changes. Third, the Oseretsky spectrum of movement, of the children with autism responded to the order of mono-movement capability, hand-movement and co-operative movement. Fourth, the movement education program was more effective for the children with autism than for the retarded children in view of motor development capability. Fifth, the movement education program was more effective for the child with autism of multi-movement characteristics.

      • KCI등재

        응급실에서 시행한 상용심전도의 효용성에 대한 고찰

        도호석,이창현,이삼범,도병수 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

        Study objectives : To determine whether routine performance of an ECG could have been safely avoided in a subset of ED(emergency department) patients admitted to a university hospital. Design : Retrospective consecutive case series. Setting : University teaching hospital. Type of participants : All patients admitted through Yeungnam university hospital during a three month period. Methods and interventions : Acceptable indications for an admission ECG were prospectively developed. Charts of all patients were reviewed to determine whether any of these were present, whether an admission ECG performed, and whether an admission ECG resulted in a change in patients management or outcome. Measurements and main result : There were 984 admissions through ED during the study period. Of these 608 patients had an ECG performed at ED. Of the 608 patients 140(23.0%) had at least one acceptable indication and 468(77.0%) had no for an ECG. Among the 140 who had an indication for an ECG at ED, 56(40.0%) patients ECG were interpreted abnormal (95% confidence interval[CI], 32%∼48%). Among the 468 who had no indications, only 3(0.64%) patients ECG were interpreted abnormal (95% CI, 0%∼1.36%) and the ECG result in a change in management, but no change in outcome (95% CI, 0%∼0.64%). Conclusion : The routine or admission ECG could have been avoided in no acceptable ED indication. We should have to try continuously for making acceptable criteria of ECG in ED of Korea, and then we have to prevent needless ECG and cardiac work up that increasing the cost and evacuation time from ED.

      • SCOPUSKCI등재

        출산에 따른 그레이브스병의 재발 및 관련이자

        임창훈,최현아,한승석,김해성,이창욱,정호연,한기옥,장학철,박원근,윤현구,한인권 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.2

        Background: Pregnancy affects the course of Graves' Disease (GD), and patients who initially maintain euthyroid function into their middle trimester with minimum doses of antithyroid drugs become exacerbated after delivery. Even patients who are completely cured, requiring no treatment during pregnancy, can relapse after delivery. In this study, we examined the postpartum changes in the thyroid functions of patients with GD, and attempted to determine the factors contributing to these changes. Methods: The study subjects were recruited from pregnant women visiting our outpatient clinic for routine prenatal evaluations. 45 women previously diagnosed with GD, who had been treated and cured with hyperthyroidism, and were no longer taking any thyroid medications, were evaluated for 1 year post delivery. Results: Among 45 patients, 20 (44.4%) developed thyroid disorders following delivery. Postpartum thyroiditis (PPT) developed in 8 patients (17.8%), and GD developed in 12 (26.0%). The onset of the PPT disease 3.1 ± 1.4 months following delivery, which was significantly earlier than the 6.7 ± 2.7 months required for the post delivery onset of GD (p=0.003). The TBII values, measured during the thyrotoxic state in each womaen, were negative in women with PPT and positive in 71.4% of women with GD (p=0.030). The duration of treatment for hyperthyroidism prior or pregnancy, the number of recurrences, and the time interval without treatment, were not associated with the development of postpartum thyroid disorders. Whereas, the mean number of past pregnancies for women who developed PPT was 3.9 ± 2.1, and was significantly higher than the 2.2 ± 1.7 for women developing no thyroid dysfunctions (p=0.044). In 13 women their initial onset of GD occurred within one year postpartum, 7 (53.8%) having had a recurrence, which was significantly higher than in women whose disease onset occurred unrelated to delivery (5 of 32 women: 15.6%). Conclusion: Women with GD developed postpartum thyroid dysfunctions in 44.4% of cases. Women whose initial disease onset occurred within one year postpartum had higher recurrences of GD, and women who developed PPT had a history of higher gravidity compared to the euthyroid women postpartum. Therefore, if women with GD develop postpartum thyroid dysfunctions, the diagnosis should be made, and a treatment modality planned, following careful considerations of the patients' past obstetric history, changes in clinical manifestations and the TBII values

      • 치환용매 변화에 따른 비대칭 Ceellulose Acetate 막의 기체투과특성

        정광보,장승현,남석태 한서대학교 산학협력연구원 부설 환경연구소 2000 환경연구소 논문집 Vol.3 No.-

        Gas permeation behavior was examined for asymmetric cellulose acetate membrane prepared by changing the acetone evaporation time and drying solvent. By changing the acetone evaporation time, the gas permeation rate decreased for the first 2 minutes and then increased gradually for the membrane of i-PrOH exchange drying. Gas permeation rate was in the order of He>N₂>O₂ and separation factor was about 1.9 for the membrane of 9 minute acetone evaporation. The permeation mechanism appears to be the combination of Knudsen flow and viscous flow. The effect of Knudsen flow was increased with acetone evaporation time, while the effect of viscous flow increased for the membrane of EtOH exchange drying.

      • KCI등재SCOPUS

        제왕절개 수술반흔에서 점액성 변화와 탈락막 변 화가 일어난 자궁내막증 2 예 및 조직면역학적연구

        김주현(Ju Hyun Kim),한치동(Chi Dong Han),허창규(Chang Kyu Huh),조창호(Chang Ho Cho),고석봉(Suk Bong Koh) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.1

        Decidualized cutaneous endometriosis infrequently arises in the absence of pelvic disease. It is described in which the histologic features included cytologic atypia, circumscription of endometrial epithelial cells with glandular or cystically dilated space, mononuclear cells within and around the endometrial nodules, and accompanied myxoid change. This histologic pseudomalignancy is not common and be misinterpreted as metastatic carcinoma or malignant tumors arising from soft tissue due to location of nodule and histologic feature. We have experienced two cases of myxoid change in decidualized cutaneous endometriosis in the abdominal scar following Cesarean section, which is presented with a brief review of the literature.

      • SCOPUSKCI등재

        In vitro Screening of Jeju Medicinal Plants for Cosmeceutical Materials

        Kim, Sang-Suk,Hyun, Chang-Gu,Lee, Jong-Sung,Lim, Ji-Hee,Kim, Ji-Young,Park, Deok-Hoon The Korean Society for Applied Biological Chemistr 2007 Journal of Applied Biological Chemistry (J. Appl. Vol.50 No.4

        One of the important functions of skin is protection from harmful environments. Many studies have explored how to prevent skin from wrinkling and the occurrence of pigmentation changes. Skin wrinkling and pigmentation changes could be caused by unusual disruption of connective tissue, the formation of free radicals and ultraviolet radiation. In this study, extracts obtained from 254 different kinds of Jeju medicinal plants were screened for inhibitory effects on tyrosinase and elastase, and for free radical scavenging effects. Four herbs, Phormium tenax, Morus bombycis, Morus alba, and Cudrania tricuspidata, were potent inhibitors of tyrosinase ($IC_{50}$ values 4.62, 5.46, 8.17, and 64.17 ${\mu}g$/mL, respectively). Aleurites fordii [$IC_{50}$: 5.29 ${\mu}g$/mL, 1,1-diphenyl-2-picrylhydrazyl (DPPH)], Distylium racemosum ($IC_{50}$: 6.14 ${\mu}g$/mL), Acer palmatum ($IC_{50}$: 5.44 ${\mu}g$/mL), and Spiraea salicifolia ($IC_{50}$: 5.25 ${\mu}g$/mL) showed good antioxidative effects. Furthermore, Distylium racemosum ($IC_{50}$: 7.51 ${\mu}g$/mL), Diospyros kaki ($IC_{50}$: 15.1 ${\mu}g$/mL), Cornus macrophylla ($IC_{50}:$ 16.59 ${\mu}g$/mL), and Psidium guajava ($IC_{50}$: 40.25 ${\mu}g$/mL) exhibited potent inhibitory effects on elastase. These results suggest that medicinal plants possessing several biological activities may be potent inhibitors of the processes involved in pigmentation increases and aging. Further investigations will focus on in vivo assays and on the chemical identification of the major active components responsible for whitening and anti-aging activity in the screened efficacious extracts.

      • KCI등재

        Numerical analysis of flow and bed change at a confluence of the Namhan River and the Seom River using a two-dimensional model

        Park Moonhyung,Kim Hyung Suk,Baek Chang Hyun 한국수자원학회 2018 한국수자원학회논문집 Vol.51 No.12

        본 연구에서는 4대강 살리기 사업 후 퇴적현상이 지배적으로 발생하는 남한강과 섬강 합류부 구간을 대상으로 2차원 수치모형인 CCHE2D 모형을 이용하여 하천의 흐름 및 하상변동에 대한 해석을 수행하였다. 대상지점 합류부는 남한강 본류의 만곡부에 지류 섬강이 유입되는 특성을 갖는다. CCHE2D 모형은 비평형 유사이송을 해석하며 소류사와 부유사 조정거리가 중요한 입력변수로 대상지점에서는 소류사 조정거리가 하상변동에 가장 큰 영향을 주는 것으로 나타났다. 수치모의 결과 유량비(Qr) 변화가 남한강과 섬강 합류부 지점에서 흐름 및 하상변동에 영향을 미쳤으며, Qr≤ 2.5인 경우에는 합류전 본류의 유속이 증가하여 흐름박리구역을 감소시켰으며 이로 인해 합류부 내측의 퇴적이 감소하였다. Qr>2.5이면 합류부 구간에 퇴적이 증가하여 사주가 형성될 가능성이 높은 것으로 나타났다. 수치모의를 통해 2013년에 발생한 유량비 변화에 의해 합류부에 고정사 주가 형성된 것을 알 수 있었다. The flow and bed change were analyzed using the CCHE2D model, which is a two-dimensional numerical model, at a confluence of the Namhan River and Seom River where deposition occurs predominantly after the “Four Major Rivers Restoration Project.” The characteristic of the junction is that the tributary of Seom River joined into the curved channel of the main reach of the Namhan River. The CCHE2D model analyzes the non-equilibrium sediment transport, and the adaptation lengths for the bed load and suspended load are important variables in the model. At the target area, the adaptation length for the bed load showed the greatest influence on the river bed change. Numerical simulation results demonstrated that the discharge ratio (Qr) change affected the flow and bed change in the Namhan River and Seom river junction. When Qr ≤2.5, the flow velocity of the main reach increased before confluence, thereby reducing the flow separation zone and decreasing the deposition inside the junction. When Qr>2.5, there was a high possibility that deposition would be increased, thereby forming sand bar. Numerical simulation showed that a fixed sand bar has been formed at the junction due to the change of discharge ratio, which occurred in 2013.

      • P177 Dermoscopic findings during the course of β -blocker treatment for infantile hemangioma

        ( Jin-hwa Son ),( Hyun-ju Jin ),( Hyang-suk You ),( Woo-haing Shim ),( Jeong-min Kim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Byung-soo Kim ),( Moon-bum Kim ),( Hyun-chang Ko ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

        <div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Dermoscopy is a useful tool for examining morphology and structure of blood vessels in vascular skin lesions like infantile hemangioma (IH). However, dermoscopic findings are not fully elucidated in the course of β-blocker treatment for IH. Objectives: To investigate changes of dermoscopic findings during the course of β-blocker treatment for IH. Methods: Superficial or mixed-type IH patients treated with topical timolol solution or oral propranolol were enrolled in Pusan National University Hospitals (Busan and Yangsan) from November 2011 to January 2016. Clinical photograph and dermoscopic findings were recorded and assessed at the baseline, 1, 2, 3 and 6 months. Results: Total 115 patients (male: 38 and female: 77 / superficial type: 48 and mixed type: 67 / timolol: 77 and propranolol: 38) were included. Diffuse light erythema tended to be diminished but milky-red area increased gradually during the course of treatment. The patients treated with oral propranolol showed more prominent changes on each dermoscopic findings than those treated with topical timolol (p=0.023 and p=0.018, respectively). But, other findings like red-globular vessels, red-dot vessels, red-circulated vessels, red-linear vessels did not show significant changes. Conclusion: Dissolution of diffuse light erythema and increase of milky-red area were significant dermoscopic findings in accordance with clinical improvement after β -blocker therapy for IH.

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