가변 광도 중합에 따른 복합레진의 중합수축에 관한 연구

임미영,조경모,홍찬의 대한치과보존학회 2007 Restorative Dentistry & Endodontics Vol.32 No.1

본 연구는 광중합형 복합레진 중합 시 기존의 중합법과 가변광도 중합형인 soft start 중합법 및 exponential 중합법 간의 중합수축효과를 비교하고자 하였다. 본 연구를 위해 3종의 복합레진 (Synergy Duo Shade, Z250, Filtek Supreme) 및 3종의 광조사기 (Spectrum 800, Elipar Highlight, Elipar Trilight)를 사용하였다. 총 중합시간은 40초로 일정하게 유지하였으며, 선형 중합수축률의 측정은 linometer를 이용하였으며, 90초간의 선형 수축률을 0.5초 간격으로 측정하였다. 재료별로 각 중합 방법별 시간에 따른 중합수축률을 one-way ANOVA test로 분석하여 최종 중합수축률에 도달하는 시간을 산출하였고, 90초 후 최종 선형 중합수축률을 two-way ANOVA test를 이용하여 재료, 광조사 방법, 재료 및 광조사 방법의 교호작용이 중합수축에 미치는 영향이 있는지를 검증하였다. 또한 90초까지의 선형 중합수축률에 대한 20초까지의 선형 중합수축률의 비를 two-way ANOVA로 비교하고, 각각의 통계치를 95% Scheffe test로 검증하였는바, 다음과 같은 결과를 얻었다. 1. Supreme을 제외한 다른 군에서는 재료 및 광조사 방법에 관계없이 대부분의 중합 수축이 광조사 후 20초 이내에 이루어졌다 (p < 0.05). 2. 90초 후, 최종 중합수축률은 재료 (p = 0.000)와 광조사 방법 (p = 0.003) 모두 유의성 있는 영향을 끼쳤으나, 재료와 광조사 방법 상호간의 작용은 영향이 없었다. 3. 90초 후 최종 중합수축률은 총 광에너지가 가장 낮은 exponential 중합법에서 유의성 있게 낮았다 (p < 0.05). 4. 20초까지의 초기 수축률은 soft start와 exponential 중합법 등 가변광도 중합이 conventional 중합법에 비하여 유의성 있게 낮은 수축률을 보였다 (p < 0.05). 본 실험 결과만을 토대로 볼 때, 가변광도 중합법은 초기 중합수축 속도를 감소시켜 수축응력을 감소시킨다고 볼 수 있다. 그러나 총 조사 광에너지의 차이로 인해 그 물리적 성질에 영향이 있을 수 있으므로 향후 이에 대한 더 많은 고찰이 필요할 것으로 사료된다. The purpose of this study was to compare the effect of exponential curing method with conventional curing and soft start curing method on polymerization shrinkage of composite resins. Three brands of composite resins (Synergy Duo Shade, Z250, Filtek Supreme) and three brands of light curing units (Spectrum 800, Elipar Highlight, Elipar Trilight) were used. 40 seconds curing time was given. The shrinkage was measured using linometer for 90 seconds. The effect of time on polymerization shrinkage was analysed by one-way ANOVA and the effect of curing modes and materials on polymerization shrinkage at the time of 90s were analysed by two-way ANOVA. The shrinkage ratios at the time of 20s to 90s were taken and analysed the same way. The results were as follows: 1. All the groups except Supreme shrank almost within 20s. Supreme cured by soft start and exponential curing had no further shrinkage after 30s (p < 0.05). 2. Statistical analysis revealed that polymerization shrinkage varied among materials (p = 0.000) and curing modes (p = 0.003). There was no significant interaction between material and curing mode. 3. The groups cured by exponential curing showed the statistically lower polymerization shrinkage at 90s than the groups cured by conventional curing and soft start curing (p < 0.05). 4. The initial shrinkage ratios of soft start and exponential curing were statistically lower than conventional curing (p < 0.05). From this study, the use of low initial light intensities may reduce the polymerization rate and, as a result, reduce the stress of polymerization shrinkage.

배지의 종류가 식중독세균의 열손상으로 부터 회복에 미치는 영향

박찬성,김경희,김미림 慶山大學校 1994 論文集 Vol.12 No.1

10^6 - 10^7 cells/ml of pathogenic bacteria, vibrio parahaemolyticus 10135, Staphylococcus aureus 196E and Listeria monocytogenes were exposed at 45, 50 and 60℃ for 60 minutes in tryptic soy broth(TSB). Following thermal stress, cells were allowed to recover in three kinds of recovery media for 24 hour. TSB, Flounder homogenate and Oyster homegenate were used for heat injured Vibrio parahamolyticus and Staphylococcus aureus where as TSB, Listeria enrichment broth(LEB) and Oyster homogenate for Listeria monocytogenes as recovery media. Heat injury of Vibrio parahamolyticus was larger Staphylococcus aureus or Listeria monocytogenes at 50℃. Recovery of heat injured cells of Listeria monocytogenes was laster than other strains. TSB was a good media for recovery of heat injured cells but Oyster homogenate was poor.

除草劑 Paraquat가 미생물의 증식에 미치는 영향

金美林,朴燦性,崔慶浩 효성여자대학교 새마을연구소 1990 새마을硏究論文集 Vol.10 No.-

Experiments were carried out to understand the inhibitory effect of chemicals, especially that of a herbicide paraquat(1,1'-dimethyl-4,4'-bipy-lidilium dichloride) against microbial growth. Bacillus megaterium (ATCC 1787) was used as the indicator microorganism in the experiment. Among the eighteens of tested chemicals(insecticides 7, germicide 7 and 4 herbicides), six kinds of germicide and paraquat revealed an aparent repression against growth of the indicator organism at the concentrations pf ten ppm. Paraquat at the concentration above 1 x 10^-3M drastically repressed not only the growth of bacterial cells but yeast cells. Re-growth of the bacterial cell was inhibited in the concomitant presence of 1 x 10^-3M paraquat within eight hours of continuous cultivation, however, it was possible when con-centration of the herbicide was lowered 1 x 10^-4M.

우리나라 논 관개용 지하수 수질 특성

김진호,조광래,임수정,이경자,경기천,엄미정,김희권,김찬용,이영한,이신찬,윤순강 한국환경농학회 2003 한국환경농학회지 Vol.22 No.4

This study was carried out to evaluate the status of the groundwater quality for paddy fields irrigation in Korea. Water samples were collected at 130 sites throughout the country. Samples were collected at three seasons-April, July and October-in 2000. According to our survey, the groundwater was found to be suitable for irrigation purpose. Average EC was shown 0.286 dS/m. Nitrate-nitrogen and Cl^(-) concentration was 5.6 ㎎/L, 32.95 ㎎/L which satisfied the Korean Standards for Irrigation Water. Nitrate-nitrogen concentration in each province was shown as following orders: Jeju (11.17 ㎎/L) > Chungnam (8.16 ㎎/L) > Gyeongbuk (6.64 ㎎/L) > Gyounggi (5.91 ㎎/L) > Chungnam (4.95 ㎎/L) > Gyeongnam (3.91 mgk) > Jeonbuk (3.50 ㎎/L) > Jeonnam (3.27 ㎎/L) > Gangwon (2.91 ㎎/L). The concentration by sampling seasons were October (6.62 ㎎/L) > July (5.88 mg&) > April (4.78㎎/L). As the soil of Jeju Province is usually derived from volcanic ash soils mainly used for upland drops, it may influence the nitrate-nitrogen concentration of groundwater. The amount of rainfall also influence the water quality. But the COD_(Cr), were shown April (3.17㎎/L) > July (2.91 ㎎/L) > October (2.40 ㎎/L), it is highly related in the basal dose of organic matter fertilizers. This study demonstrated that groundwater quality was suitable for irrigation, but continuous monitoring is recommended for agricultural policy and developing OECD agricultural environment indicators.

시클러 캡슐(세파클러 250㎎)에 대한 경보세파클러 캡슐의 생물학적동등성

조혜영,강현아,김세미,박찬호,오인준,임동구,문재동,이용복 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.1

The purpose of the present study was to evaluate the bioequivalence of two cefaclor capsules, Ceclor (Lilly Korea Co., Ltd.) and Kyongbocefaclor (Kyongbo Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of cefaclor from the two cefaclor formulations in vitro was tested using KP VIII Apparatus II method with various dissolution media (pH 1.2. 4.0. 6.8 buffer solution and water). Twenty four healthy male subjects. 22.96±1.52 years in age and 67.03±7.90 kg in body weight, were divided into two groups and a randomized 2x2 cross-over study was employed. After one capsule containing 250 mg of cefaclor was orally administered, blood was taken at pre-determined time intervals and the concentrations of cefaclor in serum were determined using HPLC method with UV detector. The dissolution profiles of two formulations were similar at all dissolution media. In addition. the pharmacokinetic parameters such as AUC_(t), C_(max) and T _(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t). C_(max) and untransformed Tmaa. The results showed that the differences between two formulations based on the reference drug, Ceclor. were -1.90%, 2.68% and -7.60% for AUCt, C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., log 0.91-log 1.06 and log 0.92-log 1.18 for AU', and C_(max), respectively). Thus. the criteria of the KFDA bioequivalence guideline were satisfied, indicating Kyongbocefaclor capsule was bioequivalent to Ceclor capsule.

제 1형 신경섬유종증 환자에서 발생한 위장관 간질종양 1예

원경준,이준,변유미,조민근,한경택,김원,홍란,임성철,김경종,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type l neurofibromatosis (NFl) Generally, the majority of GISTs are isolated neoplasm and they are sporadically found in the stomach, but the GISTs in NFl patients are usually multiple and usually found in the small intestine. We report a case of multiple GISTs in the jejunum of a 63-year-old woman diagnosed as NFl accompanied by complication of gastrointestinal bleeding, In this case, Patient had multiple cafe-au lait spots and neurofibroma on skin and had freckling on axilla and groin, and then, we made a diagnosis of NFl. Gastrointestinal bleeding is controlled by resection of multiple GISTs. Generally, only 3-5% of all gastrointestinal bleeding comes from the small bowel. Causes of small intestinal bleeding are angiodysplasia, neoplasm, NSAIDs induced ulcer etc. but, If patients have NFl accompanied by complication of gastrointestinal bleeding, GISTs on small bowel must be considered.

Macrolide resistance mechanisms and virulence factors in erythromycin-resistant <i>Campylobacter</i> species isolated from chicken and swine feces and carcasses

LIM, Suk-Kyung,MOON, Dong-Chan,CHAE, Myung Hwa,KIM, Hae Ji,NAM, Hyang-Mi,KIM, Su-Ran,JANG, Gum-Chan,LEE, Kichan,JUNG, Suk-Chan,LEE, Hee-Soo The Japanese Society of Veterinary Science 2016 The Journal of veterinary medical science Vol.78 No.12

<P>Resistance to antimicrobials was measured in 73 isolates of <I>Campylobacter jejuni</I> (<I>C. jejuni</I>) and 121 isolates of <I>Campylobacter coli</I> (<I>C. coli</I>) from chicken and swine feces and carcasses in Korea. Both bacterial species showed the highest resistance to (fluoro) quinolones (ciprofloxacin and nalidixic acid) out of the nine antimicrobials tested. Erythromycin resistance was much higher in <I>C. coli</I> (19.0%, 23/121) than in <I>C. jejuni</I> (6.8%, 5/73). The mutation in the 23S rRNA gene was primarily responsible for macrolide resistance in <I>Campylobacter</I> isolates. Several amino acid substitutions in the L4 and L22 ribosomal proteins may play a role in the mechanism of resistance, but the role requires further evaluation. A total of eight virulence genes were detected in 28 erythromycin-resistant <I>Campylobacter</I> isolates. All <I>C. jejuni</I> isolates carried more than four such genes, while <I>C. coli</I> isolates carried fewer than three such genes. The high rate of resistance highlights the need to employ more prudent use of critically important antimicrobials, such as fluoroquinolones and macrolides, in swine and poultry production, and to more carefully monitor antimicrobial resistance in <I>Campylobacter</I> isolates in food animals.</P>

Wolbachia infection according to geographical location in Aedes albopictus (Diptera: Culicidae) in Korea

Chan Hee Park,HyungWoo Lim,HyunWoo Kim,Mi Yeoun Park,Wook-Kyo Lee,Jong Yul Roh,Kyu Sik Chang,E-Hyun Shin 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.10

The intracellular endosymbiont bacterium Wolbachia is currently considered the most abundant in arthropods. Many Wolbachia manipulate host reproductive systems, it lead to male-killing, cytoplasmic incompatibility, parthenogenesis and feminization of genetic males with large impact on host ecology and evolution in arthropods. In this study, we investigated the distribution of Wolbachia infection in Ae. albopictus according to geographical distribution. We selected 9 areas and collected Ae. albopictus, these areas were distinguished with mountain chain and waterway. Whole genomic DNA were extracted from collected specimens and PCR analysis were accomplished in each specimen using Wolbachia specific primers such as 16S and WSP genes. As a results, we collected 730 Ae. albopictus at least 30 specimens in each area. Wolbachia infection rate showed different patterns between geographical region. Cheonbook, Cheonnam and Yeongdong showed 100% infection rate followed by Jeju (97%), Chungchung (88%), and Gyungnam (85%) with two Wolbachia marker genes. Our results indicated that Ae. albopictus are commonly infected with Wolbachia, it is possible that Wolbachia may act as endosymbiont in Ae. albopictus regardless of geographical region. Although, low infection rate of Wolbachia, we need continuous survey for the evaluation of Wolbachia strain within Ae. albopictus as a vector of dengue fever.

The combined management of cervical pessary and cerclage for twin pregnancy with short cervix

( Chan Mi Lim ),( Hae Rin Jeon ),( Da Hoe Jeong ),( Suk Young Kim ) 대한산부인과학회 2021 대한산부인과학회 학술대회 Vol.107 No.-

Maternal and Perinatal Outcomes in Pregnancy by Chronic Kidney Disease Stage Based on Midterm Glomerular Filtration Rate

( Chan-mi Lim ),( Min-jung Choi ),( Hae-rin Jeon ),( Sun-young Jung ),( Suk-young Kim ) 대한주산의학회 2020 Perinatology Vol.31 No.2

Objective: Chronic kidney disease (CKD) is a known risk factor of pregnancy that increases the rates of preterm birth, intrauterine growth restriction, and preeclampsia. And maternal CKD may worsen due to pregnancy itself. However, few studies have examined these problems in Korea. Methods: The cases of 29 women with CKD who delivered singleton at our institute between 2006 and 2018 were retrospectively reviewed. Cases with major fetal malformation, intrauterine fetal death, a history of kidney transplantation, or insufficient information for the parameters were excluded. The subjects were divided into early-stage (stages 1 and 2) and late-stage (stages 3 to 5) groups according to the midterm glomerular filtration rate (GFR). Demographic profiles, renal function, perinatal complications, and changes in GFR from pre-conception to postpartum were compared and analysed. Results: The incidence of preeclampsia (28.6% vs. 75.0%; P=0.038), anemia (28.6% vs. 75.0%; P=0.038), cesarean section (42.9% vs. 100.0%; P=0.009), small for gestational age (14.3% vs. 62.5%; P=0.019) and the need for neonatal intensive care unit (38.1% vs. 87.5%, P=0.035) were significantly higher in the late-stage group than those in the early-stage group. Gestational age at delivery (38.1 vs. 35.4 weeks, P=0.021) and birth weight (2,970 vs. 2,200 g, P=0.006) were significantly lower in the late-stage group than those in the early-stage group. GFR decreased significantly after delivery compared to pre-conception in both group (P=0.028, both). Conclusion: Late-stage CKD is a poor prognostic factor for pregnancy outcomes. Pregnancy deteriorates renal function even in early-stage. Close monitoring and management are required for pregnant women with any stage of CKD.