Pancuronium과 d-Tubocurarine의 가토 골격근에 미치는 상가 효과에 관한 연구

윤건중 충남대학교 대학원 1983 국내석사

Administration of pancuronium 5㎍/kg, d-Tubocurarine 50㎍/kg and combination of pancuronium and d-Tubocurarine were given to same genus rabbit during intravenous urethane anesthesia to determine the degree of neuromuscular effect prior to the administration of each drug, rabbit was firmly fixed to specially constructed metal armboard. The sciatic nerve was stimulated by means of train of four stimulation (4 volt, 6msec, and 2㎐) The evoked twitch and tracing of muscle of lower extremity was recorded contineously on physiograph. When rabbit was stable, drug of each group was given. The results were summarized as follows: 1. The pancuronium-d-Tubocurarine combination was significant more potent relaxation (p.0.005) than effect of each of the individual drug given alone, 2. The significant muscle relaxtion of pancuronium-d-Tubocurarine combination was appeared at 1 minute and most potent relaxation was observed at 10 minute after drug a administration, at 25 minute, 93 % of this relaxation of pancuronium-d-Tubocurarine combination was recovered. 3 Blood pressure and pulse rate of pancuronium-d-Tubocurine combination were not changed, but respiration was depressed at 1 minute Most significant depression was observed at 10 minute and duration of depression was prolonged about 30 minute.

지하철역사 및 터널의 예측모델을 고려한 공기질 개선 인공지능형 시스템의 장치제어 로직 개발에 관한 연구

윤건중 건국대학교 대학원 2013 국내석사

서울 지하철은 지난 1974년 1호선 개통이래 지속적으로 지하철이 건설되어 현재 9개 노선에 이른다. 최근 도심의 도로 정체 구간이 많아지면서 지하철 이용자들이 늘어나고 있다. 처음 지하철은 단순히 수송수단으로서의 역할만 요구 되어왔으나, 현재는 지하철 이용 빈도가 많아지고 지하철 역사 내에 체류하는 시간이 길어짐에 따라 하나의 생활공간으로서의 역할도 만족시켜야 하는 상황이다. 또한 전반적인 생활수준이 향상됨에 따라 지하철 내의 쾌적함과 안전성에 대한 인식이 높아지고 있으며, 환경개선에 대한 문제가 계속 제기되고 있는 실정이다. 요즘 공기질 문제가 더욱 심각해지고 있다. 서울 메트로는 일상 대중교통수단으로 사람들이 이용하는 지하철 역사의 공기오염을 줄이기 위해 스크린도어(PSD) 설치, 고압살수차 운영 등 공기질 개선에 힘쓰고 있다. 본 연구는 대합실이 크고 출구가 8개인 3호선 대청역에서 실험을 실시하였다. 지하철 역사 및 터널에 대한 인공지능형 시스템의 로직을 개발하고, 대합실, 승강장 및 터널에서 PM10 농도를 측정하여 실험을 진행하였다. 인공지능형 시스템을 피드백 제어 하여 대합실, 승강장 및 터널의 환기팬을 제어 하였다. 그 후에 예측 모델을 인공지능형 시스템에 적용하여 환기팬 효율을 높이고 전력소비도 감소하게 하였다. 예측 모델은 실시간 데이터 알고리즘, 예측 데이터 알고리즘, factor 등으로 만든다. 적합한 factor를 실험을 통하여 찾고 예측 모델을 인공지능형 시스템에 넣어 좋은 공기질 농도와 낮은 인버터 주파수를 유지할 수 있도록 하였다. 실험을 통하여 통합된 시스템이 잘 작동하는지 테스트하고 검증하였다. 대청역 이외의 다른 역사에 인공지능형 시스템을 적용하고자 한다면, 그 역사의 PM10을 실시간으로 측정하고 본 연구에서 개발한 제어로직을 통해 무리 없이 적용할 수 있다.

Interferon 및 gamma-globulin이 實驗的 Pneumocystis carinii 肺炎의 治療에 미치는 影響

윤건중 忠南大學校 大學院 1992 국내박사

This study was performed to obtain the additional informations on the therapeutic effects of interferon and gamma-globulin in experimental Pneumocyatis carinii pneumonia. Total 135 female BALB/c mice were used. The mice were administered an immunosuppressive regimen of 2.5 mg of cortisone acetate injected subcutaneously twice weekly, a low(8w) protein diet, and tetracycline(1㎎/㎖) for 11 weeks. At 9 weeks, the mice were randomly divided into control and five different experimental groups(15 mice per group). Control group received no anti-P. carinii therapy, but experimental groups administered trimethoprim-sulfamethoxazole(TMP-SMZ; 10-50 mg/mouse/day), recombinant mouse interferon-gamma(rIFN-r: 5×10⁴units/mouse/day) and mouse gamma-globulin(r-globulin: 20 ㎎/mouse/day) for 3 weeks. The 5 mice were sacrified at weekly intervals to study anti-P. carinii effects in control and experimental group. Evaluations of drug therapy were based on body weights of mice, histopathologic and electron micrascopic findings of lungs, and number of P. carinii cysts by Gomori's methenamine silver stain. Body weights of mice were significantly increased in combination therapy of TWP-SMX with rIFN-r or r-globulin(p<0.05), and treatment with TMP-SMZ alone(p<0.05). But it was little effect in the treatment with r-globulin alone. Histopathologic findings of P. carinii pneumonia were best improved in combination therapy of TMP-SMZ with rINF-r. Treatment with rINF-r alone was similar histopathologic findings as compared with treatment with TMP-SMZ. In electron microscopic findings of P. carinii pneumonia, the number of trophozoites and cysts were reduced in treatment with either TMP-SMZ or rIFN-r as compared with control group. And most of cysts were empty-cyst form or containing one or two intracystic bodies. Treatment with either TMP-SWZ or rIFN-r significantly reduced the number of cysts in the P. carinii pneumonia(p<0. 05) But r-globulin alone was ineffective in eradicating P. carinii cysts . From this study, treatment with IFN-r caused a significant reduction in the number of cysts in P. carinii pneumonia in the lung, and combination therapy of TMP-SWZ with IFN-r were synergistic effects in the treatment of P. carinii pneumonia in mice. But further study will be needed to understand the action mechanism of IFN-y in the treatment of P. carinii pneumonia.

전자기록 전문가를 위한 재교육에 관한 연구 : 미국과 호주의 사례를 중심으로

윤건중 명지대학교 기록정보과학전문대학원 2020 국내석사

학력 혹은 특정한 자격요건과 배타적이고 독점적인 위치로 일정한 영역을 차지하고 있는 전문직 종사자에게 필요조건을 넘어 필수조건으로 꼽을 수 있는 건 지속적인 지식의 추구이다. 한편 폭발적으로 발전하는 사회와 더불어 기록관리환경은 종이기록에서 전자기록으로 바뀌었고, 이와 더불어 기존의 기록연구사들 또한 지속해서 변화하는 전자기록을 기존의 지식을 이용해 다루는데 불편함을 겪게 되었다. 전문적인 기록관리 지식을 다루는 재교육은 지속적으로 이루어지고 있지만 이와 더불어 전자기록 전문가 양성을 위한 재교육이 필요한 것이다. 현재 미국은 SAA(Society of American Archivists)에서 ‘DAS(Digital Archives Specialist Curriculum and Certificate Program)’를 운영하여 디지털 아카이브 전문가를 양성하고 있으며 호주의 NAA(National Archives of Australia)는 공공기관에서 일하는 직원들이 정보와 데이터를 다루는 데 필요한 기술과 지식을 식별하여 ‘정보 관리 및 데이터 기능(Information Management and Data Capabilities)’을 구성하여 기준으로 삼고 있다. 본 연구에서는 미국의 DAS와 호주의 정보 관리 및 데이터 기능에 대해 자세히 알아보고 이를 통해 기록관리 전문직으로써 급속도로 변해가는 전자기록 환경에 대응하기 위한 재교육 방안에 대해 분석, 제시하고자 한다. It is the continued pursuit of knowledge that can be cited as a prerequisite beyond the necessary requirements for a professional worker who has a certain area of education or specific qualifications and exclusive and exclusive location. Meanwhile, with the explosive development of society, the record management environment changed from paper to electronic records, while existing record researchers also experienced difficulties in continuously using existing knowledge. Re-training, which deals with professional record management knowledge, is ongoing, but in addition, re-training is necessary to foster e-recording experts. Currently, the U.S. operates the Digital Archives Specialist Curriculum and Certificate Program (DAS) at Society of American Archivists (SAA) to train digital archive professionals, and Australia’s National Archives of Australia (NAA) uses Information Management and Data Capabilities to address the information and data required by public agencies. In this study, we will learn more about DAS and Australia's information management and data functions and analyze and present re-education measures to respond to the rapidly changing electronic record environment as a record-keeping professional.

스포츠 스킬과 정지 및 동체시력에 관한 연구

윤건중 부산대학교 교육대학원 1999 국내석사

The purpose of this study was to analyze the relationship between sports skill, dynamic visual acuity and static visual acuity in the nonathletic high school students. The subjects were 226 nonathletic male high school students who were 16 years old and live in Pusan city. The subjects divided by the level of sports skill, and then the upper group was consisted 22 students(Group A), and lower group was consisted 22 students(Group B). The result of this study is as follows ; 1. The static visual acuity(right eye, left eye, and both eyes) was higher Group B than Group A, but there was nonsignifacnt. 2. The dynamic visual acuity was higher significantly Group A than Group B(p<.001). 3. The relationship between dynamic visual acuity and static visual acuity showed the posivive relationship but there was nonsignificant. 4. The relationship between sports skill and dynamic visual acuity showed the posivive relationship significantly(p<.001), but between sports skill and static acuity showed negative relationship with a nonsignificant. In conclusion, the result of this study is supported the applicability visual training program at the pick athlets out and it could be very useful to improve sports performance, ability of referee's decision in area with a various sports competition, and traffic safety education, and so on. If we use the visual training program at the physical education class, we can expect that improved the sports skill in the nonathletic students