http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
민경업 대한알레르기학회 1999 천식 및 알레르기 Vol.19 No.5
첨단 과학의 발전에 따른 질병 발생에 관한 병태생리의 이해와 새로운 치료약제의 도입에도 불구하도 알레르기 질환은 최근 20년 사이에 전세계적으로 증가하고 있는 추세이다. 국내에서도 암, 만성 성인병과 더불어 국민의 3대 만성 질환의 하나이고 소아에서는 이제 가장 흔한 만성 질환으로 알려져 있다. 1972년 대한알레르기학회가 창립되고 1981년 '알레르기' 학회 잡지가 발간되면서 알레르기 질환의 발생, 진단, 치료, 예방 등에 대한 관심이 증가하여 알레르기 여러 분야에서 논문들이 활발하게 보고되기 시작하였으며 여러 가지 학술활동 및 환자와 가족들을 위한 알레르기 교육이 시작되었다. 그러나 이러한 활동은 주로 알레르기 전문 클리닉이 설치되어 있는 병원들에 내원한 환자들을 대상으로 시행되었기 때문에 알레르기 질환의 증가 추세와 비교할 때 부족한 감이 있었다. 이에 대책으로 대한 천식 및 알레르기학회는 대한 소아알레르기 및 호흡기학회와 공동으로 1999년 5월 15일부터 21일까지 1주간을 제1회 알레르기주간으로 제정하고 다가오는 21세기에는 알레르기 질환의 발병을 줄이기 위하여 알레르기 예방을 위한 "7대 권장사항"을 채택하였다 (Table.1). 이는 알레르기질환의 발볍에 영향응 미치는 인자들 중 학문적으로 그 중요성이 널리 인정된 것들을 국내의 상황에 맞게 채택하였다. 이에 이러한 캠페인의 전체적인 필요성과 각 항목의 선정 배경을 밝히고자 한다.
알레르기 환자에서 ImmunoCAP 시스템을 이용한 환삼덩굴 및 점박이응애항원에 대한 특이 IgE치 측정: 피부반응도 및 E L ISA 결과와의 비교
김현아 ( Hyoun Ah Kim ),예영민 ( Young Min Ye ),허규영 ( Gyu Young Hur ),김승현 ( Seung Hyun Kim ),서창희 ( Chang Hee Suh ),남동호 ( Dong Ho Nahm ),박해심 ( Hae Sim Park ) 대한천식알레르기학회 2006 천식 및 알레르기 Vol.26 No.2
Background and Objective: Japanese hop pollen (Hop J) and two spotted spider mite (TSM) are common allergens in this country. The aim of this study was to validate a new immunoCAP test for detecting allergen-specific IgE to Hop J and TSM compared to skin reactivity and ELISA results. Method: Ninty-five allergy patients showing more than 2+ response on skin prick test to Hop J, 131 allergy patients showing more than 2+ response on skin prick test to TSM and 60 non-atopic healthy controls were enrolled. Skin prick testing was performed using homemade Hop J pollen and TSM extracts. The specific IgE levels to both homemade allergens were measured by ELISA, which were compared to those of the immunoCAP system. Result: The positive rates of serum specific IgE to Hop J were 57% by ELISA and 51% by Pharmacia immunoCAP system among 95 patients tested. The positive rates of serum specific IgE to TSM were 28% by ELISA and 50% by immunoCAP system among 131 patients tested. A significant correlation was found in specific IgE level between ELISA and the immunoCAP system (r=0.63 for Hop J and r=0.61 for TSM, P<0.05). Conclusion: The new immunoCAP system for detecting serum specific IgE antibodies to Hop J pollen was comparable to the results of other in vivo and in vitro test and can be applied for the diagnosis of Hop J-allergic patients. New immunoCAP system to TSM was superior to the ELISA test, and can be used for screening TSM-sensitive patients. (Korean J Asthma Allergy Clin Immunol 2006;26:129-135)
응급실 내원 소아청소년에서 심한 식품알레르기의 발생 빈도와 임상 특징
이수영 ( Soo Young Lee ),김경원 ( Kyun Won Kim ),이현희 ( Hyun Hee Lee ),임대현 ( Dae Hyun Lim ),정혜리 ( Hae Lee Chung ),김성원 ( Sung Won Kim ),이소연 ( So Yeon Lee ),양은석 ( Eun Seok Yang ),이정민 ( Jeong Min Lee ),김규언 ( Ky 대한천식알레르기학회 2012 천식 및 알레르기 Vol.32 No.3
Background: Incidence and severity of childhood food allergy increased during the past 2 decades and that pediatric emergency department visits and death occurring due to food-induced anaphylaxis also increased in Western countries. Methods: To evaluate the incidence and clinical characteristics of pediatric emergency department visits due to severe forms of food allergy in Korea, data were collected from 305 with urticaria, angioedema or anaphylaxis of 78,889 children aged ≤18 or younger than 18 years who visited the emergency departments between of 9 hospitals in 8 cities in Korea June 2008 and March 2009. The incidence and clinical characteristics of childhood food allergy were evaluated using the detailed medical records. Results: Of 78,889 children, 169 (0.214%) showed food-related systemic urticaria, angioedema or anaphylaxis. Of the 57 children with anaphylaxis, 36 of which (63.16%) were food-related. The incidence of food-related anaphylaxis was 4.56 per 10,000 pediatric emergency department visits. Cutaneous symptoms (92.8%) were the most common anaphylaxis followed by cardiovascular (29.82%), gastrointestinal (28.07%), and respiratory symptoms (24.56%). The most common offending food allergen was fish, followed by cow`s milk, other seafoods, chicken, pork, egg, walnut, pupa, peanut, beef and buckwheat. There were no cases of death from anaphylaxis in this study. Conclusion: This is the first study to evaluate the incidence of pediatric emergency department visits and severity of childhood food allergy in Korea. The causative food allergens and clinical characteristics of pediatric emergency department visits due to food allergy in Korean children have been surveyed.
알레르기 질환 환자에서의 알레르기 반응도와 인성 특성의 관계
김조자,김용순,박지원,강성숙,홍천수,이기영,박인용,민성길 대한천식알레르기학회 1989 천식 및 알레르기 Vol.9 No.2
The differences of psychologic tests were found between groups of allergic diseases, who noted the degree of skin reactivity on allergy skin test. In the present study the MMPI and allergy evaluations were given to 115 patients with bron- chial asthma, allergy rhinitis, both of them and other allergic diseases, who visted at Allergy Clinic in Severance Hospital, Yonsei University College of Medicine from March 1988 to September 198K There were differences of personality charac- teristics between groups of allergic reactions. The weak skin reactivity group scored higher on depression, psychasthenia, social introversion (p<0.05) and feminity (in male patients)(p<0.01) and scored lower on psychopathic deviste than those of strong skin reactivity group. Therefore these findings confirm the previous conclusion that there are measurable, important psychological differences within groups of allergy patients, related to degree of demonstrable allergy reactivity. And allergy p a.tients had neurotic tendence. The patients who noted that their allergic simptom- developed on psychic stresses showed higher scores on hypochondriasis (p<0.05), depression (p 0.05) and hyste'ria (p<0.05) than those of the patients who did not note any relationship between development of allergy symptoms and psychic stresses. And the patients who noted that their allergy simptoms were relapsed by psye4ic stresses showed higher scores on hypochondriasis (p,0.05), depression (p <0.05), hysteria(p<0.01) and social introversion (p <0.05) than those of patients who noted that the relapse of their allergy symptoms was not related to psychic stresses. The results repremnt that psychic factors in addition to pure antigen-antibody reactions will participate in development and aggravation of allergy symptoms.
영유아 식품알레르기 예방을 위한 최신 의견: 수유와 이유식을 중심으로
송태원 ( Tae Won Song ),안강모 ( Kang Mo Ahn ),이수영 ( Soo Young Lee ) 대한천식알레르기학회(구 대한알레르기학회) 2015 Allergy Asthma & Respiratory Disease Vol.3 No.5
Food allergy is common with the prevalence of 5%-7% in Korean children. The development of food allergy is likely to reflect interactions between genetic factors and environmental exposure. To prevent food allergy, early exposure to food allergens through maternal and infant diet have been investigated. Recently, guidelines for primary prevention of food allergy have been updated, and consensus communication on early peanut introduction has been demonstrated. For the first 4-6 months after birth, exclusive breast-feeding is recommended, and if impossible, extensively or partially hydrolyzed infant formula can be recommended in high-risk infants. Introducing complementary foods is recommended between 4 and 6 months of age, even in case of potentially allergenic foods such as egg, milk, and wheat. For the prevention of peanut allergy, early peanut introduction could be better than late peanut introduction in selected high-risk infants. However, infants who developed food allergy should avoid ingestion of specific offending foods. (Allergy Asthma Respir Dis 2015;3:320-325)
최정희 ( Jeong-hee Choi ),이창률 ( Chang Youl Lee ) 대한천식알레르기학회(구 대한알레르기학회) 2018 Allergy Asthma & Respiratory Disease Vol.6 No.2
Oral allergy syndrome (OAS) is an IgE-mediated allergy caused by cross-reacting antigenic determinants in pollens and various fruits, vegetables, and nuts which are known as the most common food allergy in adults. Cross-reactive antigenic proteins include pathogenesis-related-10 protein, profilin, cross-reactive carbohydrate determinant and lipid transfer protein. The prevalence of OAS has been reported at up to 70% of birch pollen allergy. A nationwide multicenter study in our country has recently reported that the prevalence of OAS in Korea is 41.7% of pollen allergy. Typical symptoms of OAS are tingling, itching sense and edema of lips, mouth, and throat immediately after ingestion of raw fruits, vegetables, or nuts. These can progress to systemic symptoms including anaphylaxis. The diagnosis can be made by typical clinical history in patients with pollen allergy. Skin prick test using fresh fruits extracts can be helpful in confirming sensitization to foods, which has better sensitivity than commercial skin prick test or serum specific IgE test. Treatment of OAS is to avoid causative foods. Self-injectable epinephrine should be considered in the case of anaphylaxis. Allergen-specific immunotherapy to pollens has also been tried. (Allergy Asthma Respir Dis 2018;6:85-89)