장기간 항갑상선제 투여 후 임의 중단 뒤 재복용시 발생한 무과립구증 1 예

김승만;김태영;박수영;배영환;서영경 정은주;김태균;권민정;박정현;이순희 인제대학교 2011 仁濟醫學 Vol.32 No.-

Agranulocytosis, one of the major side effects of antithyroid a gents, probably occurs in less than 0.25% of cases treated with antithyroid agents. It usually occurs within the first several weeks or months after the initiation of therapy, when drug dosage is higher. Most reported cases of agranulocytosis have occurred during the first 3 months of therapy. We describe here a rare case that did not experience the side effect for 6 years of antithyroid agent treatment but presented with agranulocytosis in one month after re-exposure. It suggests that the major side effect such as agranulocytosis can occur in patients who had undergone prior uneventful antithyroid drug therapy.

잠김 금속판을 이용한 경골 골절의 치료에 대한 임상적 경험 및 초기 결과

권영호,정구희,박영균 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

Background : By this study, we evaluated the efficacy of locking compression plate in the treatment of a fractured tibia. Materials and Methods : eighteen tibial fractures were treated by percutaneous plating with locking compression plate. They were composed of nine cases of proximal fracture, two cases of comminuted shaft fracture and seven cases of distal fracture. The results were retrospectively evaluated by the knee and ankle joint motion and walking ability. Results : All fractures were healed except one. The average time for fracture healing was 16.5 weeks(range, 8-24 weeks). Complications included a genu valgus case, but there was no complication of superficial or deep infection. All patients had the recovery of knee and ankle joint motion to the level of pre-injury and could walk without crutch. Conclusion : The locking compression plate(LCP) enables the minimally invasive percutaneous plating technique to fix the tibial fracture and can be selected for the tibial fixation, especially comminuted or metaphyseal fracture because the fixed angle stability of LCP is sufficient to maintain the fracture stability and early joint motion.

감응성막의 전기적 성질을 이용한 유기 가스 반응 특성

김도균,이준호,유승엽,장정수,권영수 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

The electrical properties of Maleate copolymer (C_(18)MA-VE_(2)) and Itaconate copolymer (C_(18)ITA-VE_(2)) Langmuir-Blodgett (LB) films for in-plane were investigated to develop the gas sensor. The C_(18)MA-VE_(2) and C_(18)ITA-VE_(2) were used as sensitive materials and deposition on the slide-glass substrate using LB method which could control the thickness in the molecular order (Å). The current-voltage (I-V) characteristics were measured to investigated the response characteristics in chloroform, acetone, ethanol and methanol gases. The conductivity of sensitive films were 10^(-)7[S/cm] for an in-plane. The change of conductivity was occurred by behavior of organic gases, which mean that the behavior of organic gases could be analyzed using conductivity change and application to gas sensor. In the experimental results, the relation between sensitive films and organic gases could be divided by three-type. Thus, we could analyze the modeling of the response characteristics of organic gases using the conductivity change of sensitive films.

한국산 길쭉먼지벌레족의 수리분류(Ⅱ)

朴鐘均,權容正 慶北大學校農業科學技術硏究所 1996 慶北大農學誌 Vol.14 No.-

韓國産 길쭉먼지벌레族을 대상으로 "NC" 값을 인정하지 않은 상태에서 定性的 形態形質을 根據로 表現論的 數理分類方式을 利用한 群分析을 실시하였다. 그 結果, 비록 일부 種에서는 傳統分類 結果와 다소 一致하지 않은 경우도 있었으나 대부분 經驗的 分類와 類似한 傾向을 나타내었다. 그리고 대부분 種들이 期待한 屬 또는 亞屬내에 分布하였다. A numerical taxonomy based on the phenetic characters of 59 Korean Pterostichini species is conducted to determine the effect on the assessment of the 7 different methods combined by 3 similarity or dissimilarity coefficients. using 87 morphological multistate characters.

은행엽 물추출물이 흰쥐의 흉부대동맥 혈관이완에 미치는 영향

鄭權洙,金亨煥,安德均,崔湖榮 대한본초학회 2001 大韓本草學會誌 Vol.16 No.2

We have examined the relaxational response of the Ginkgo Folium water extract on isolated thoracic aorta from sprague dawley rat (300~350g) in the presence and absence of endothelium and the vasodilator nitric oxide. Segments of thoracic aorta obtained from rats immediately after delivery were mounted in organ baths superfused on a polygraph. We found that the thoracic aorta segments responded to the Ginkgo Folium water extract with a dose-dependent vasorelaxation. At 2.0 ㎎/㎖ Ginkgo Folium water extract, the relaxational response with and without endothelium were 75.8% and 6.9% of the maximum KCI-response. The Phenylepinephrine and 5-hydroxytrptamine - induced contraction at 10^-4M were inhibited by 77.3% and 75.8% after addition(2.0 ㎎/㎖) of the Ginkgo Folium water extract. After pre-treatment of the thoracic aorta with N^G-monomethyl-L-arginine(10^-4M), the vessels contracted in response to the nitric oxide synthase inhibitor. The present results show that nitric oxide may act as a crucial signal in the vasodilative action. In conclusion, Ginkgo Folium water extract-induced relaxation in the isolated rat thoracic aorta was composed of endothelium-dependent and dose-dependent relaxation. Endothelium-dependent relaxation may be mediated by release of endothelium derived relaxing factor, nitric oxide.

폐결핵치료 중인 환자에서 Rifampicin에 의해 유발된 위막성 대장염 2예

김봉진,권균홍,임창섭,김자영,홍정범,옥미선,배용목,김지연 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

Pseudomembranous colitis (PMC) is a disease caused by Clostridium difficile proliferation. The causative drugs are clindamycin, third-generation cephalosporins, flouroquinolone and so on. Rifampicin has been reported as a cause of PMC in the 1980s, and the frequency of PMC is increasing because rifampicin is a first line drug for anti-tuberculosis therapy. Two patients were recently admitted to our hospital due to watery diarrhea for 1 month and they were diagnosed with PMC by sigmoidoscopy. Their onset age were 74, 72 years old and latent period of symptoms were 60, 129 days, respectively. In one case, the patient displayed coexisting hypertension and diabetes. The clinical symptoms improved after discontinuing the rifampicin and then administering oral metronidazole. We report here on two cases presumed to be rifampicin-induced PMC.

正氣天香湯 및 加味正氣天香湯의 效能에 대한 實驗的 硏究

朴贊基,權貞南,金榮均 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

Effects of Jeongkicheonhyangtang and Kamijeongkicheonhyangtang have been experimentally studies. The results have been obtained as follows: 1. It is proved that analgecic effect on sample I group and sample II group are clearly decreased than control group. Thus, the statistically significant decrease is p<0.005. 2. It is proved that anti-inflammatory effect on sample I group and sample II group are decreased compare to control group. Thus, the statistically significant decrease of sample I group is p<0.05 in 30 and 60-minute, p<0.01 in 90-minute, and p<0.005 in 12 and p<0.005 in 90, 120 and 180-minute. 3. It is proved that appearance of gastric ucler is decreased compare to the control group and the statistically significant decrease is p<0.05. 4. It is proved that plasma epinephrine contents of sample I and II group are clearly decreased compare to the Control Group and the statistically significant decrease is p<0.005 5. It is proved that plasma norepinephrine contents of sample I group is drastically decreased compare to the control group and the statistically significant decrease is p<0.005. 6. It is proved that plasma dopamine contents of sample I and II group are decreased than the control group and statistically significant decrease of the sample I group is p<0.005, and those of the sample II group is p<0.05. As the above mentioned results of experiment, it is believed that Jeongkichenhyang and Kamijeongkicheonhyang have effect for stress.

특발성 결절성 지방층염

고명권,조문균,정현,김영근 순천향대학교 1994 논문집 Vol.17 No.2

Idiopathic nodular panniculitis is an inflammatory disease of subcutaneous fat tissue which is clinically characterized by recurrent crops of nodular panniculitis. Some cases are accompanied by systemic features such as fever, malaise, abdominal pain and arthritis. We report a case of idiopathic nodular panniculitis in 36 year-old woman, who had erythematous subcutaneous nodules on the extremities, trunk and face accompanied by various general symptoms such as fever, malaise, abdominal pain and weight loss.

체외충격파 쇄석술 시행 후 5년 뒤 발생한 요관 협착 및 농신장 1예

이현승,권균홍,조용건,김봉진,임창섭,김자영,허동,임학 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

A 40-years-old woman was admitted to this hospital with flank pain and high grade fever for 2 weeks. As a matter of her past history, extracorporeal shock wave lithotripsy (ESWL) was performed for treatment of renal stones 5 years ago. Her abdominal CT findings were hydronephrosis with pyonephrosis and renal stones. Antibiotics administered for 5 days had no effects on her symptom improvement. A right ureteral stricture was noticed by ultrasonography follow up. We inserted double J stent and continued antibiotics therapy for 10 days, and then her fever was disappeared and flank pain was improved. ESWL is one of the most important treatment of renal and ureteral stone. However, its complications should not be negligible including bleeding, pain, ureteral obstruction, infection and so on. Complications of ESWL can be divided into acute and chronic courses. When we treat pyelonephritis patient with past history of ESWL, possibility of ureteral stricture must also be considered. In this study we report a case of pyelonephritis caused by ureteral stricture, possibly as a chronic complication of ESWL performed 5 years earlier

Microstructure and properties of cross-roll rolled and heat treated metastable TiNbSn alloy.

Jung, Taek-Kyun,Choi, Ho-Joon,Kim, Kyung-Taek,Shin, Young-Chul,Lee, Hyo-Soo,Lim, Sung-Chul,Kwon, Hyouk-Chon,Hanada, Shuji American Scientific Publishers 2014 Journal of Nanoscience and Nanotechnology Vol.14 No.10

<P>A (Ti-35mass%Nb)-4mass%Sn alloy was cross-roll rolled with a reduction ratio of 70% in which the roll axes are tilted by 5 degrees away from the transverse direction of the rolled sample and then aged at 250 degrees C for 2 h. Cross-roll rolling was found to increase yield strength and Young's modulus, simultaneously. Yield strength was higher in cross-roll rolled than in conventionally rolled at same reduction ratio. Yield and tensile strength further increased by a low temperature ageing by ψ precipitation hardening and microstructure refinement. Yield and tensile strength of the aged 70% cross-roll rolled sample were higher than those of the aged 70% conventionally rolled one.</P>