Antioxidant Activity and Whitening Effect of Lindera erythrocarpa Extract

Min ?Chul Kang,Ryeo Kyeoung Ko,Ju-Yeop Lee,Haeng-Bum Kim,Bong-Seok Kim,Jong-Heon Han,Seong-Hyun An,Gi-Ok Kim 한국생물공학회 2008 한국생물공학회 학술대회 Vol.2008 No.10

국내외 수용가 맞춤형 수력발전시스템 현대화개발 및 실증

오민환(Min-Hwan Oh),신기석(Ki-Seok Shin),임재황(Jae-Hwang Lim),윤여창(Yeo-Chang Yun),김현아(Hyun-Ah Kim),강석원(Seok-Won Kang),백종명(Jong-Myung Paik),이준용(Jun-Yong Lee) 대한전기학회 2017 대한전기학회 학술대회 논문집 Vol.2017 No.10

초임계 이산화탄소를 이용하는 친환경 공정에 의한 다공성 고분자의 제조

강세란,홍성수,이민규,이석희,천재기,주창식 한국환경과학회 2004 한국환경과학회지 Vol.13 No.3

An experimental study on the preparation of monolithic porous polymers by environmentally friend process in supercritical carbon dioxide has been carried out. Polymerization mixture composed of a cross-linking monomer, initiator and functional co-polymer was charged in the reactor with sapphire window. After the system was purged with a flow of CO₂ for 15 min, the reactor was pressurized with liquid CO₂ up to 100 bars. The reactor was isolated from and placed back to the system via quick connector for shaking until the mixture had become fully homogeneous. The reactor was then heated and pressurized to the required reaction conditions and left overnight. After cooling and CO₂ evacuation, the polymer was removed from the reactor as dry, white, continuous monoliths. The effect of experimental conditions on the physical properties of porous polymer was systematically examined, and it was found that monomer content had a major effect on the physical properties of the polymers.

鐵 陽極 溶出反應에 의한 燐成分 除去

강민수,김형석,박승조 동아대학교 환경문제연구소 1995 硏究報告 Vol.18 No.1

This study was on the removal of phosphorus compounds in domestic and synthetic wastewater using iron-anode electrolytic reactor. The experiments were performed at different current, reaction time and flow rate. The results are as follows ; 1. For the synthetic wastewater with the flow rate of 1.5 ℓ/min and 0.75 ℓ /min, the removal efficiencies were 97% and 98%, respectively. The order conditions of this continuous experiments are current density 2.54 A/dm² and reaction time 20 minutes. 2. The optimal conditions of the batch experiment for synthetic wastewater were current density 0.95 A/dm² and reaction time 3.0 minutes with no addition of electrolyte. With electrolyte, the optimal conditions were current density 2.54 A/dm² and reaction time 1.0 minutes. For the both experiments, the removal efficiencies were far over 97%.

고혈압 관리를 위한 의사지원결정시스템의 데이터 마이닝 접근

강석민,조승연,채영문,김태수,호승희 대한간질학회 2003 대한간질학회지 Vol.9 No.2

중소기업에서의 품질/환경 통합경영시스템 구축 사례 연구

강민석,장원철,박병춘 한국품질경영학회 2003 품질경영학회지 Vol.31 No.1

This study deals with a case analysis on the implementation of ISO 9000/14000 Integrated Management System. The intention is to provide some general guidelines, in particluar, to small-to-medium-sized companies that are planning to introduce the Integrated Management System. First we briefly review each of the ISO 9000 series, ISO 14000 series and Integrated Management System. We then investigate the case of a small-sized company that have built and is successfully operating the Integrated Management System. We start with introducing the company, and then examine the background and the procedure for implementing the Integrated Management System. We investigate effects of the Integrated Management System, which are the main focus of this paper. This study is meaningful in that, to our best knowledge, it is the first field report appearing in the literature in regard to the actual implementation of ISO 9000/14000 Integrated Management System in Korea.

建築物에 있어 太陽電池의 태양광 추적기법 適用 가능성에 관한 實驗的 硏究

강성범,오민석,김회서 대한건축학회 2003 대한건축학회논문집 Vol.19 No.9

The amount of electric power produced by Photovoltaic(PV) depends on the density of daylight incident. In addition to the development of high efficient PV, a study on the methods for maximizing the density of daylight incident to PV surface is essential to increase the production of electric power. In this respect, many studies on light tracking and gathering device have been conducted in the advanced countries such as U.S. and Japan. However, those studies in Korea are still in an early stage. Therefore this study aims to present the optimal tracking system for the application of PV to buildings considering domestic weather condition. In this study, the tracking type, the interval of tracking offset and optimum integration of tracking system were investigated.

제주마의 체형에 관한 연구

강민수,정창조,강태숙,박희석,김동후,정재준 제주대학교 농과대학 제주도축산문제연구소 1986 畜産論叢 Vol.1 No.1

한국인에서 혈소판 당단백 Ⅱb/Ⅲa 유전자 다형성과 관동맥 성형술 후 재 협착과의 관계

이민수,이정우,김보영,임대승,강정아,김정희,김윤철,성보영,최성준,성인환,전은석 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2

Platelet aggregation is the final pathway of acute coronary syndrome such as acute myocardial infarction and unstable angina. Platelet glycoprotein IIb/IIIa is a membrane receptor for fibrinogen and yon Willebrand factor and it plays an important role in platelet aggregation and in the pathogenesis of acute coronary syndrome. It is known that polymorphism of the gene that encoding platelet glycoprotein IIb/IIIa(PI^A1/A2) is strongly related to acute coronary syndrome in Caucasian, but not in Koreans. We investigated relationship between platelet glycoprotein llb/Illa gene polymorphism and restenosis of coronary artery after angioplasty in Koreans. Total 371 patients(M=251. F=120) were enrolled. Angioplasty group comprised 143 patients who underwent coronary angioplasty, and in the angioplasty group, restenosis group comprised with the 65 patients who had restenotic lesion over 50% of luminal diameter in follow-up coronary angiography. Normal group comprised 153 patients who had no significant angiographic lesion and variant angina group comprised 75 patients who were positive in ergonovine test. Genomic DNA was extracted from peripheral arterial blood. To determine the frequency of P1^A1/A2 genotype, polymerase chain reaction(PCR) was done and the product was restricted with Mspl. 3%. agarrose gel electrophoresis showed restriction fragment length polymorphism. Clinical profile and risk factor were also reviewed. Among all 371 patients of study group, genotype of only one patients in restenosis group if is proven to be PI^A1/A2 heterozygote. All patients of normal study group, no restenosis group, and the other patients in restenosis group have an PI^A1 homozygote genotype. In our study, platelet glycoprotein IIb/Illa polymorphism has no relationship with restenosis of the coronary artery after angioplasty in Koreans. But the genotypic frequency of platelet glycoprotein IIb/IIIa gene polymorphism in Koreans is concordant with that of previous studies.

우울증 환자 치료에 있어서 Tianeptine과 Sertraline의 효과와 안전성 비교

이민수,강성민,기백석,연병길,오병훈,이철,채정민,백인호 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.2

연구목적: 주요 우울증의 치료에 있어서 티아넵틴과 써트랄린의 임상적 효과와 안정성을 비교하기 위하여 연구를 시행하였다. 방법: DSM-IV 진단 기준에 의거하여 주요 우울증의 진단기준에 부합되고 17항목 해밀턴 우울척도 점수가 14점 이상인 환자를 대상으로 하였다. 총 40명의 환자를 무작위적 방식에 따라 티아넵틴 치료군과 써트랄린 치료군으로 분류하였다. 선탠된 환자에서 다른 항우울제를 복용하고 있는 경우 7일 이상의 약물 배설기간을 가진 후 티아넵틴과 써트랄린을 각각 6주간 투여하였으며, 기준점, 1주후, 2주 후, 4주 후, 6주 후에 HAM-D, MADRS, 그리고 CGI, COVI 등을 사용하여 평가하였다. 본 연구기간 중 발생된 모든 부작용은 부작용의 발생 및 소실 시기, 심한 정도, 발생 빈도, 관련 조치 및 결과에 대하여 증례기록서에 기록하도록 하였다. 결과: 30명(티아넵틴군 15명 ; 써트랄린군 15명)이 6주간의 연구를 완결하였고 티아넵틴 치료군에서는 1일 37.5mg을 투여하였으며 써트랄린군에서는 1일 평균 64.0±22.5mg을 투여하였다. 본 연구 결과 HAM-D, MADRS, CGI 상에서 두 군 모두에서 치료 1주 후부터 유의한 감소를 나타내었으며 이는 2주 후, 4주 후, 6주 후에도 지속적인 감소를 보였고 두 군간에 항우울 효과의 차이는 없었다. 활력징후, 일반 혈액학, 생화학, 심전도 검사 등에서는 두 군 모두 유의한 변화는 없었다. 티아넵틴과 관련된 부작용으로 흔히 보고한 증상은 오심(33.3%), 복부 불쾌감(26.7%), 구강 건조(20.0%), 두통(13.3%)등 이었고 써트랄린 치료군에서는 구강 건조(53.3%), 두통(46.7%), 오심(33.3%), 그리고 식욕 부진(33.3%)등으로 티아넵틴군에서 보다 적은 발현빈도를 보였다. 결론: 티아넵틴은 우울증의 치료에 있어서 효과적이고, 내약성이 우수한, 안전한 항우울제이다. Objective: This study was designed to evaluate the efficacy and safety of tianeptine and sertraline in the treatment of patients with depression. Method: The study was done on the patients with major depression diagnosed by DSM-IV, who had aHamilton Rating Scale for Depression(HAM-D) score ≥ 14 on the first 17 items of the HAM-D. A total of 40 patients were randomly assigned to tianeptine group and sertraline group. Tianeptine and sertraline were prescribed to each group. 6 weeks of each medication was carried out after 7 days of drug excretion period. Evaluation using 17 item HAM-D, Montgomery and Åsberg Depression Rating Scale(MADRS), Clinical Global Impression Scale (CGI), and Covi Scale was done on the baseline and after 1 week, 2 weeks, 4 weeks, and 6 weeks. Regrding all side effects that had occurred during the period of our study such as their developed/disappeaed time, severitien, incidences, managements and results have been recorded. Results: A total of 30 patients(tianeptine group 15 ; sertraline froup 15) finished the 6 weeks of research. 37.5mg of the daily dose was regularly prescribed to the tianeptine group, the average amount of 64.0±22.5mg of the final daily dose was prescribed to the sertraline group. Total 17 item HAM-D scores, total points of MADRS and CGI showed significant decrease after 1 week in each treatment froup and continous decrease after 2, 4 and 6 weeks ; and no difference was found between tianeptine group and sertaline group in the antidepressant efficacy. Also there were no significant changes in vital sign, CBC, chemistry, and EKG in each treatment group. The common reported side effects of tianeptine were nausea(33.3%), epigastic distress(26.7%), dry mouth(20.0%), headache(13.3%) and those of sertraline were dry mouth (53.3%), headache(46.7%), nausea(33.3%), anorexia(33.3%). Conclusion: According to the results, tianeptine was effective in improvement of depressive symptoms and was well tolerated and safe in patients with depression.