임상 ; 한국 산모와 신생아의 비타민 D 영양 상태 조사

나보미 ( Bo Mi Na ),노소정 ( So Jung No ),김미정 ( Mi Jung Kim ),한헌석 ( Heon Seok Han ),정은환 ( Eun Hwan Jeong ),한영희 ( Young Hee Han ),현태선 ( Tai Sun Hyeun ) 대한주산의학회 2007 Perinatology Vol.18 No.4

목적: 한국 산모와 신생아의 비타민 D 영양 상태를 조사하여 비타민 D 부족의 발생률과 그 정도를 알아보고, 이에 영향을 미치는 요인들을 분석하였다. 방법: 2004년 8월부터 2005년 7월까지 충북대학교병원 산부인과에서 출산한 총 181쌍의 산모와 건강한 만삭아를 대상으로 하였다. 분만시 산모와 제대혈의 혈청 25-OH 비타민 D3(25OHD3), alkaline phosphatase (AP), 칼슘(Ca), 인(P), 부갑상선 호르몬(PTH) 농도를 측정하였으며, 모성 면담과 설문 조사를 통하여 자외선 조사량과 비타민 D의 일일 평균 섭취량을 구하여 비교분석하였다. 결과: 1) 산모와 신생아의 혈청 25OHD3 농도는 각각 23.4±9.9과 16.9±7.5 ng/mL이었다. 2) 8 %의 산모와 22%의 신생아가 비타민 D 결핍 상태였으며, 70%의 산모와 신생아에서 부족 상태를 보였다. 3) 산모와 신생아의 25OHD3 농도는 강한 양의 상관관계를 보였다(r=0.7270, p<0.0001). 4) 산모와 신생아의 비타민 D 영양 상태에 가장 큰 영향을 미치는 요인은 출산 계절로 하절기(6~11월)에 높았다. 5) 다중회귀분석 결과, 산모에서는 출산 계절과 분만 방식이, 신생아에서는 산모의 25OHD3와 분만 방식이 비타민 D 농도와 연관성이 있는 것으로 나타났다. 결론: 한국 산모와 신생아는 비타민 D 영양 결핍이나 부족 상태에 있는 경우가 많았으며, 출산 계절이 비타민 D 영양 상태에 가장 큰 영향을 미치는 것으로 나타났다. Objective: To evaluate the vitamin D nutritional status and its influencing factors in Korean mothers and their newborn infants. Methods: Maternal (n=181) and cord blood (n=180) serum concentrations of vitamin D (25OHD3), calcium, inorganic phosphorus, alkaline phosphatase, intact parathyroid hormone were measured at the time of delivery. We defined vitamin D deficient, insufficient, and sufficient as 25OHD3 <11, 11~30, and >30 ng/mL, respectively. Using questionnaires, average duration of sun-light exposure (minutes/day) and dietary intake of vitamin D (μg/day) were obtained. Results: 1) The mean 25OHD3 level in mothers was 23.4±9.9 (range 4~71.6) ng/mL, and in newborns, 16.9±7.5 (range 0.9~53.6) ng/mL. 2) 8.3% of mothers and 22.2 % of newborns were vitamin D deficient, and 70% of both mothers and newborns were insufficient. 3) Maternal 25OHD3 showed a strong positive correlation with cord blood 25OHD3 (r=0.727, p<0.001). 4) The most significant risk factor for low 25OHD3 levels was the season of birth (June through November) in both mothers and newborns. 5) In multiple logistic regression analysis, the season of birth and the mode of delivery remained significant for maternal vitamin D status, whereas maternal 25OHD3 and the mode of delivery remained significant for neonatal vitamin D status. Conclusion: In conclusion, vitamin D deficiency or insufficiency was relatively common in Korean mothers and their newborn infants, and the most significant risk factor for low vitamin D status was the season of birth.

정신지체아 어머니의 부담감과 삶의 질과의 관계

한순화,이강오,나덕미 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

This is a correlational study analyzing the relationship between burden and qualify of life in mothers of mentally retarded children. The subjects for this study were 104 mothers of retarded children at a retarded welfare center, early training of retarded children rehabilitation center, and retarded school in Kwangju. Data were collected from 1st Feb. to 27th Feb, 1998. The instruments used for this study were the burden scale developed by Seo, and the quality of life scale developed by Yang. The data were analyzed by the t-test, ANOVA, and Pearson's Correlation Coefficient using SPSS. The results of this study were as follows : The mean score of burden:3.08, The mean score of quality of life: 2.60, The mean score of subscale : family relationship: 3.20, self-esteem and general life; 3.08, friends and relationships; 2.70, physical and psychological health; 2.56, economical life (cloths. food) ; 2.52, job and daily work; 2.27, recreation, 2.07, recreation, job and daily work scored lowest. The analysis of the level of burden according to general characteristics of the subjects showed statistically significant differences in husband's help (F=4.21, p=.018), and the degree of retardation in the children(F=13.67, p=.000). The 1st hypothesis, "e mothers' burden differed according to the degree of their children's MR"as supported. The analysis of qualify of life according to general characteristics of the subjects showed statistically significant differences in living state(t= 2.19, p= .031) , the health state of mothers(F=4.17, p= .018), husband's help(F= 11.55, p= .000) , and the degree of retardation in the children(F=3.76, p= .013). The 2nd hypothesis, "e mothers' quality of life differed according to the degree of their children's MR"as supported. The correlation between burden and quality of life was statistically significant(r=-0.562, p=.000). The 3rd hypothesis, "e lower the level of burden, the higher the quality of life" was supported. In conclusion, it was found that the lower the level of burden is, the higher the quality of life becomes.

백악질 골화성 섬유종의 치과적 접근 : 증례보고 A CASE REPORT

한지혜,김재곤,백병주,양연미,이선영 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.2

백악질 골화성 섬유종은 가장 흔히 발생하는 섬유 골성 병소(fibro-osseous lesion)로서, 경계가 분명하고, 느리게 성장하는 팽창성의 양성종양이다. 임상적으로 하악골의 소구치와 대구치 부위에서 발생하고, 여성에게서 2배 정도 호발하며, 주로20대에서 30대 사이에서 발견된다. 백악질 골화성 섬유종은 섬유성 이형성증을 포함한 다른 섬유 골성 병소와 감별되어야 한다 백악질 골화성 섬유종의 또 다른 형태인 유년형 골화성 섬유종은 15세 이하에서 발생하며 빠르게 성장하고, 좀 더 골 파괴적인 양상을 보인다. 치료는 병소의 크기에 따른 절제술이고, 재발은 드물다고 알려져 있다. 본 증례는 우측 하악 견치의 미맹술을 주소로 내원한 12세 남자 어린이로, 백악질 골화성 섬유종으로 진단 후, 외과적 적출술을 시행하여 양호한 치유과정을 보이기에 보고하는 바이다. Cemento-ossifying fibroma of the jaws is well circumscribed, generally slow-growing, benign lesions which en-large in an expansile manner. Clinically, it presents as a slowly enlarging lesion commonly in the premolar-molar area of the mandible and only occasionally in the maxilla and other locations. It occurs twice as often in females and primarily in the 20 to 30 year age group. Differential diagnosis should be performed, preferably with other fibro-osseous lesions such as fibrous dysplasia. A faster growing and more destructive variant of cemento-ossifying fibroma sometimes occurs in patients under age 15 and is termed juvenile (aggressive) ossifying fibroma. Treatment is surgical removal with the extent depending on the size and location of the individual lesion. Recurrence is considered rare. A case involving a 12-year-old male patient with delayed eruption of right mandibular canine is discussed. Following an incisional biopsy, the histopathologic diagnosis established was cemento-ossifying fibroma. After the surgical enucleation of the lesion, no sign of recurrence was detected.

치근 우식 수복에 사용되는 심미성 수복물의 변연누출에 관한 연구

한진순,임미경 大韓齒科保存學會 1993 Restorative Dentistry & Endodontics Vol.18 No.1

AbstractThe purpose of the study was to evaluate the degree of the marginal leakage of esthetic restorative materials on root caries restoration. 120 cavities were prepared to 90?butt joint on all margins on the crown and root portion, and divided into 4 groups.The four groups of cavity were filled with Amalgam(Dongmuyung Dental Alloy Co., Ltd, KOREA), Silux?3M Co., USA)-Scotch Bond 2?3M Co., USA), Silux?All Bond?BISCO USA), and GC Fuji II?G-C Co., JAPAN) respectively. The apical margin of the preparation was finished to leave a flash of restorative material. The coronal margin of the preparation was finished not to leave a flash of restorative material. All specimens were sectioned longitudinally with Isomet Low speed saw(Buether Ltd, USA). The degree of dye penetration was evaluated as the parameter of marginal leakage under the stereoscope.The results were as follows. 1. At the enamel and dentin/cementum margins, the margin were finished to leave a flash of material showed less marginal leakage than that were finished not to leave a flash of material(P<O.OOl). 2. The enamel margins showed less marginal leakage than the dentin/cementum margins(P< 0.001). 3. There was no significant difference in the degree of the marginal leakage between Silux? Scotch Bond 2?group and Silux?All Bond?group.

기저귀 사용실태와 피부자극도 조사 : Cost, Environment, and Skin Irritability

한정석,김동건,신현숙,정예리,정태석,채선미 한국모자보건학회 2000 한국모자보건학회지 Vol.4 No.1

고지방식을 섭취한 랫드에서 김치유산균의 콜레스테롤 저하효과

조미선, 노정미, 임형준, 한선경, 신명수, 이완규 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.2

본문참고

악성 위궤양의 형태를 보인 원발성 위결핵 1예

한종대,이동욱,심성준,류운석,안현택,박찬욱,김배영,이미선 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

배우자 지지가 미취학아동 어머니의 양육스트레스와 삶의 질에 미치는 영향

채선미,강희선,이한주,신현숙 한국모자보건학회 1999 한국모자보건학회지 Vol.3 No.2

서울시 교직원의 고혈압 실태파악과 그 요인에 관한 연구

신선미,김종희,한규종,이희우 韓國學校保健學會 2004 韓國學校保健學會誌 Vol.17 No.1

Purpose : To describe epidemiological characteristics and related factors in school personnel with hypertension. Method : 5,384 school personnel (2,638 males and 2,746 females) received physical examination at the Seoul School Health Center in 2002. blood pressure(BP) was classified by JNC 7th report. Normal BP is systolic BP <120 and diastolic BP<80, prehypertension BP is 120-139 or 80-89mmHg, stage 1 hypertension BP is 140-159 or 90-99, and stage 2 hypertension >=160 or >=l00 mmHg. each group was evaluated by gender. We used multiple regression and logistic regression. Results : Normotension was 20.13% in d e s and 48.65% in female, prehypertension 43.4% in males and 3.06% in females, stage 1 hypertension 26.38% in males and 10.99% in females, stage2 hypertension 9.59% in males and 3.2% in females. the older age group had higher distribution of stage 1 hypertension and stage 2 hypertension. The means and abnormal rates of BMI, blood sugar, total cholesterol, GOT, GPT, and GTP was higher when their blood pressure was higher. However, an alcohol habit among lifestyle factors had an inverse effect. Higher Bp was correlated to a &her BMI, FBS, and cholesterol-like dose response. In stage 1 hypertension, the related factors of hypertension for males were BMI, amount of cigarettes smoked, exercise, blood sugar, total cholesterol, and GTP. In stage 1 hypertension, age, BMI, exercise, blood sugar, total cholesterol were related factors in female. In stage 2 hypertension, age and smoking were related factors in male, and age, BMI, and cholesterol in female. Conclusions : It is possible to intervene in all related factors of hypertension except age through life-style modification and appropriate medical management. Active health promotion is needed in School personnel.

한국해안으로부터 Purple, Non-Sulfur Photosynthetic Bacterium, Rhodobacter sp. EGH-24의 분리 및 특성

차미선,김기한,조순자,이나은,이정은,이재동,이상준,박재림 한국환경과학회 2003 한국환경과학회지 Vol.12 No.12

A species of facultative photo-organotrophic, purple, non-sulfur bacterium was isolated from the 47 point at west and south coast of Korea in September 2001. Separated 13 samples of changes with red color under 28~32 ℃, 3000 lux, anaerobe conditions for 7 days cultivated in basal medium. For pure isolation from 13 samples, we used agar-shake tube method (0.4 % agar) and separated 5 strains through 13-repetition test. EGH-24 and EGH-30 was identified as the same strain through the RAPD(Random Amplified Polymorphic DNA)-PCR of strain EGH-9, EGH-13, EGH-23, EGH-24, EGH-30. Four isolates cultivated in synthesis wastewater for wastewater biodegradation test. EGH-24 was selected with efficient wastwater treating strain. Based on the results obtained from morphology, nutrient requirements, major bacteriochlorophyll content, 16S-rDNA phylogenetic analysis, EGH-24 strain may be identified as a new strain of the genus Rhodobacter and named Rhodobacter sp. EGH-24.