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      • 일주기 리듬을 어떻게 측정할 것인가?

        정석훈 대한수면연구학회 2009 Journal of sleep medicine Vol.6 No.2

        Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center Human behaviors are affected by light-dark cycle. The suprachiasmatic nucleus (SCN) in the anterior hypothalamus generates endogenous 24-hour rhythm, which is mentioned as circadian rhythm. Circadian rhythm in human being can be assessed by measuring the circadian rhythmic profile in serum level of melatonin or cortisol, or core body temperature. In addition, rating scales such as Morningness-Eveningness Questionnaire (MEQ) or Composite Scale also are useful to assess the sleep/wake cycle or circadian patterns of human. Actigraphy, a portable device that records movement, can be used to measure the sleep/wake cycle or circadian patterns objectively over extended periods of time. In this review, the methods to measure the circadian rhythm are focused on

      • KCI등재

        안축장에 따른 백내장수술 전후 전방 구조 및 렌즈 위치의 변화 비교

        정석훈,김선주,정소향 대한안과학회 2020 대한안과학회지 Vol.61 No.1

        Purpose: In this study, we evaluated changes in the anterior chamber structure and lens position before and after phacoemulsification in eyes grouped by axial length (AL). Methods: This study included 65 eyes (16 short eyes [AL < 22.5 mm], 33 normal eyes [22.5 mm < AL < 25.0 mm], and 16 long eyes [AL > 25.5 mm]) that underwent cataract surgery. Pre- and postoperative anterior chamber depth (ACD) was measured using Pentacam® and IOL Master®. In addition, we evaluated the anterior chamber angle (ACA), anterior chamber volume (ACV), epithelium-iris distance, and iris-lens (intraocular lens [IOL]) distance. Results: The change in ACD was significantly smaller in long eyes (Pentacam®, p = 0.000; IOL Master®, p = 0.001). The change in ACA was significantly larger in short eyes (p = 0.000), and the change in ACV was significantly smaller in long eyes (p = 0.000). The change in the epithelium–iris distance was significantly smaller in long eyes (p = 0.000), and the change in the iris-lens (IOL) distance was significantly smaller in short eyes (p = 0.000). Conclusions: In short eyes, changes in ACD, ACA, and ACV were found to be larger than those of other groups as the iris moved backward. In long eyes, greater backward movement of the IOL was observed. Therefore, the appropriate IOL power should be chosen, considering the postoperative position of the IOL during cataract surgery of short and long eyes. 목적: 백내장수술 전후 안축장 길이에 따른 전방의 구조 및 인공수정체의 위치를 비교하고자 하였다. 대상과 방법: 백내장수술을 실시한 65안(짧은 군[안축장 < 22.5 mm], 16안; 정상군[22.5 mm < 안축장 < 25.0 mm], 33안; 긴 군[안축장> 25.5 mm], 16안)을 대상으로 수술 전후 Pentacam®과 IOL Master®로 앞방깊이의 변화를 분석하였고, Pentacam®으로 전방각, 전방부피, 각막상피-홍채전면까지의 거리 그리고 홍채전면-수정체(인공수정체)전면까지 거리의 변화를 분석하였다. 결과: 수술 전후 앞방깊이 변화는 안축장이 긴 군에서 유의하게 가장 적은 증가를 보였다(Pentacam®, p=0.000; IOL Master®, p=0.001). 또한 수술 전후 전방각의 변화는 짧은 군에서 가장 큰 증가를 보였으며(p=0.000), 전방 부피의 변화는 긴 군에서 가장 적은 증가를 보였다(p=0.000). 그리고 수술 전후 각막상피-홍채전면까지의 거리 변화는 긴 군에서 가장 적은 증가를(p=0.000), 홍채전면-수정체(인공수정체)전면까지의 거리 변화는 짧은 군에서 가장 적은 증가를 보였다(p=0.000). 결론: 짧은 안축장환자에서 백내장수술 전후 앞방깊이, 전방각 및 전방 부피가 더 크게 증가하고 홍채가 뒤로 더 밀리며, 긴 안축장환자에서는 인공수정체가 더 뒤로 많이 밀리는 것을 확인할 수 있었다. 따라서 안축장이 짧거나, 긴 군에서 백내장수술 시 술 후 인공수정체 위치를 감안하여 인공수정체의 도수를 선택해야 할 것이다.

      • KCI등재

        The DBST Index, the Discrepancy Between Desired Time in Bed and Desired Total Sleep Time: The Possible New Sleep Index Predicting Severity of Insomnia

        정석훈 대한수면학회 2022 sleep medicine research Vol.13 No.2

        Background and Objective We considered the concept of the DBST, the discrepancy between a patient’s desired time in bed (TIB) and desired total sleep time (TST). The DBST index can be used to easily assess a patient’s thoughts on their desired TST and dysfunctionally long TIB. This study aimed to explore whether the DBST index can predict the severity of insomnia.Methods A total of 374 members of the general population participated in this e-survey study. The participants answered questions regarding their bedtime, sleep onset time, wake-up time, desired TST, and desired TIB, and psychological symptoms were assessed using the Insomnia Severity Index (ISI), Patients Health Questionnaire–9 items (PHQ-9), Dysfunctional Beliefs and Attitudes about Sleep–16 items (DBAS-16), and Glasgow Sleep Effort Scale (GSES).Results The DBST index was significantly correlated with the ISI (r = 0.20, p < 0.01), PHQ-9 (r = 0.15, p < 0.01), GSES (r = 0.14, p < 0.01), DBAS-16 (r = 0.16, p < 0.01), desired TST (r = -0.62, p < 0.01), and desired TIB (r = 0.52, p < 0.01). Linear regression analysis showed that insomnia severity was predicted by persistent preoccupation with sleep (beta = 0.64, p < 0.001), dysfunctional beliefs about sleep (beta = 0.06, p < 0.001), depression (beta = 0.23, p < 0.001), and DBST (beta = 0.32, p = 0.035). The DBST directly influenced insomnia severity, and this association was shown to be mediated by dysfunctional beliefs and attitudes about sleep, preoccupation with sleep, and depression.Conclusions The DBST index could be a possible new sleep index due to its relationship with insomnia severity, depression, dysfunctional beliefs about sleep, and preoccupation with sleep. Further studies are needed to explore the consistency of the clinical sample.

      • KCI등재

        32P를 이용한 대두의 토양별 인산 및 석회 시용량에 관한 연구

        鄭錫薰,盧浚晶,朴根龍 韓國作物學會 1979 한국작물학회지 Vol.24 No.1

        32 P 표지 중과석과 칼슘으로 대두에 있어서 밭토양별 인산흡수계수에 의한 인산질 비료와 석회의 합리적인 시용량을 알고자 본시험이 수행되었다. 1 ) 석회의 시용은 기개간지, 미개간지 공히 생육 및 수량을 좋게 하였다. 2) 인산시용은 기개간지는 인산흡수계수 5% 미개간지는 15%에서 좋은 경향을 보였으며 석회와 인산간의 상호관계는 인정할 수 없었다. 3) 32 P 표지 중과석에 의한 시용인산의 기여도는 기개간지는 미개간지보다 다소 높은 수치를 나타내었다. 4) 기여도를 산출한 결까 미개간지는 석회시용구구(P320.2~0.3miu ) 14~16%가 석회무시용구 14~17%로 근소한 차이를 보였다. 5) 기개간지에서는 석회시용구(32 P 0.2~0.3 miu ) 21%가 석회무시용구 14~17%에 비해 높은 경향을 보 였다. This experiment was earned out with 32 P labeled phosphate and lime to determine the optimum amount of phosphate and lime fertilizers to soybean under various types of soil. The determination was made by the index of absorption of phosphate by soybean plants. The index of phosphate was 854 (mg/100g) in non matured soil. Due to the capability of neutralization of calcium the PH of the soil was raised to 6.5. The highest yield was obtained in matured soil at the index of phosphate absorption at 5% level. The degree of contribution of phosphate in. non matured soil showed slightly higher tendancy than that in matured soil.

      • 잎담배 액아유전에 관한 연구 I. 액아유전의 유전분리와 상관에 관한 연구

        정석훈,황주광,손세호 한국연초학회 1983 한국연초학회지 Vol.5 No.1

        Due to the wide and effective use of sucker controlling chemicals, gentic studies on the suckering habits of tobacco plants have long been neglected. So, to investigate the genetic basis of suckering, crosses between "Little Dutch" and "Cuban" were made, and subsequent generations, $F_1F_2,\;BC_1,\;BC_2,$ and parents were grown on the field. Several morphological characters were measured and the relation among them were analyzed. Correlation coefficients between leaf shape and sucker leaf shape, and the number of suckers and sucker weight were 0.25 and 0.42, both sighificant at 1 % level. But negative correlation between number of suckers per plant and that of leaves was observed, though statistically not significant. Dominance was observed in the number of suckers and amount of suckers produced, and the heritability of sucker shape was calculated as high as 0.88. And two paris of genes seemed to be involved in the inheritance of sucker shape, and narrow leaf appeared as dominant in the $F_1$.inant in the $F_1$.

      • 감자바이러스 Y 및 역병 저항성 연초 버어리종 신품종 KB 110의 육성 및 농경적 특성

        정석훈,최상주,조천준,조명조 한국연초학회 1997 한국연초학회지 Vol.19 No.2

        The vein-necrosis strain or potato virus Y (PVY-Vff) and black shank (Phytophlhora parasitica roar. nicotianae) causes severe damage on burley tobacco(Wicotiana tabacum L.) in Korea, A new burley tobacco resistance to PVY and black shank, KB 110, was developed by Korea Ginseng and Tobacco Research Institute. It was developed from the cross of Burley 21 with TC 591 in 1990, and was backrossed to Burley 21 in the following season. TC 591 has resistance to PVY and moderate resistance to race 0 of black shank, but it is susceptible to tobacco mosaic vim (TMV). KB 110 was evaluated for its resistance to PVY, TMV and black shank in the greenhouse and at fields for preliminary and performance trials. KB 110 which has secreting glandular trichomes was resistant to PVY-VN, TW and black shank. It had an erect growth habit and two more leaves per plant than that of Burley 21, and matures two to three days later. It yielded approximately 3 percent more cured leaf than the standard cultivar Burley 21, but other plant characteristics were very similar to those of Burley 21. It had acceptable standards for chemical and physical characteristics of lured leaf on regional farm test in 1995-1997. KB 110 produced average yields of good quality tobaccos and was appeared to be resistant to PVY inwhere occurrence of the virus are severe chronic at burley growing area.

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