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이형길 대한뇌졸중학회 2000 Journal of stroke Vol.2 No.1
Background : Association of Graves’ disease and Moyamoya disease has been rarely described. We here with report one such patient. Case : A 25-year-old woman was admitted to our hospital due to left hemiparesis and left homonymous hemianopsia. Five years prior to admission, she was diagnosed as having hyperthyroidism, which had not been adequately treated. On admission, a thyroid function test showed total tri-iodothyronine T 3) of 583ng/dl, thyroxine(T4) of 32.5μg/dl, and thyroid stimulating hormone(TSH) of 0.11mIU/ml. Brain MRI showed a high signal lesion in the right frontal area on T2 weighted image. A conventional cerebral angiography showed narrowing of the bilateral A1 and M1 arteries and the collateral net-like vessels (rete mirabile) consistent with Moyamoya disease. Conclusion : Graves’ disease and Moyamoya disease may co-occur. The possible pathophysiologic mechanisms may include genetic abnormality and immunologic derangement. However, the association could be an epiphenomenon. Korean Journal of Stroke 2000;2(1): 108~111