자궁난관에 발생한 지방종 1 례

이지신,이상룡,신승권,박명호,양해관,이성봉 대한산부인과학회 1995 Obstetrics & Gynecology Science Vol.38 No.1

저자들은 본 성골롬반 병원 산부인과에 입원한 환자에서 자궁난관에 발생한 지방종 1예를 경험하였기에 증례보고와 아울러 문헌고찰하는 바이다. Lipoma is defined as a benign tumor composed of a finely encapsulated multilobulated mass of mature adipose tissues. Lipoma is one of the most common of all genign neoplasms and may arise almost anywhere in the body, but tubal lipoma is uncommon benign tumor, only 13 case have been found in the international literature. It is not clearly defined clinical symptoms, not diagnosed prior to surgical intervention or autopsy. Most were discovered as incidental finding. We experienced a case of tubal lipoma, coincidental finding during cesarean section and so we present it with brief review of literature.

체강삼출액의 진단에 있어서 유세포분석에 의한 DNA 함량 측정의 유용성

이지신,정상우,Lee, Ji-Shin,Juhang, Sang-Woo 대한세포병리학회 1997 대한세포병리학회지 Vol.8 No.1

The specificity of cytologic examination in effusions is high but the sensitivity is low. Therefore, various ancillary methods for the detection of malignant cells in effusions have been proposed. The presence of an aneuploid cell population is generally considered diagnostic of malignancy. The purpose of this study is to determine whether the routine use of flow cytometry adds to standard cytologic evaluation in effusions. We did flow cytometric DNA analysis in 76 effusions(28 malignant and 48 benign fluids). All the 48 benign effusions were diploid. There were 12(42.9%) aneuploid and 16(67.1%) diploid malignant effusions. Based on these results flow cytometric DNA analysis had a sensitivity of 42.9% and a specificity of 100%. These results suggest that flow cytometric DNA analysis may be a useful adjunct to conventional cytology, but its principal limitation is us relatively low sensitivity.

한국채택국제회계기준 도입 이후 외국인 투자에 영향을 미치는 기업특성 분석

이지신,김용식,박상훈 한국회계학회 2013 회계저널 Vol.22 No.2

This study investigates whether the corporate characteristics affecting foreigners' investment change after K-IFRS adoption. We use investment amount and ownership of foreigners and we use both of the level and the change of the variables to analyse the factors. From the result of the level of the variables, size, stock returns, dividend, accounting quality, the number of analysts, and accounting conservatism are significantly positively related to foreigners' investment, and debt ratio is significantly negatively related to foreigners' investment. Also, foreigners invest more in the firms with high stock returns and high accounting quality in 2011 than in 2010. From the result of the change of the variables, foreigners' investment increases as size increases and debt ratio decreases by GAAP reconciliation. Especially, we document that foreigners' investment increases as profitability decreases by GAAP reconciliation, which means that foreign investors consider the expected profit in the future rather than the current profit at present when they make investment decisions. 본 연구는 K-IFRS를 도입한 이후에 외국인 투자자의 국내 투자에 영향을 미치는 기업특성 요인이 변경되는지 여부를 분석하였다. 외국인 투자자의 국내 투자요인의 변경 여부를 확인하기 위하여 투자금액과 지분율을 사용하였으며, 수준(level)과 변화(change) 값을 모두 사용하여 분석하였다. 수준(Level) 값을 이용한 선형회귀분석 결과, 기업규모가 클수록, 주가수익률이 높을수록, 배당이 많을수록, 회계품질이 높을수록, 재무분석가의 수가 많을수록 외국인투자가 증가하고, 부채비율이 높을수록, 회계보수성이 낮을수록 외국인투자가 감소한다. 또한 주가수익률과 회계품질은 2010년보다 2011년에 외국인투자와 더욱 밀접한 관련이 있다는 것을 알 수 있다. IFRS 도입 이후에 수익률이 높은 기업과 회계품질이 높다고 보편적으로 인정되는 Big 4 회계법인이 감사하는 기업에 더 많은 투자를 하고 있으며, 외국인의 투자가 국내 투자수익률과 회계품질에 더욱 영향을 미칠 것으로 예상되는 결과이다. 변화(Change) 값을 이용한 선형회귀분석 결과, GAAP 조정에 따른 기업규모가 증가할수록, 부채비율이 감소할수록 외국인투자가 증가한다. 특히 GAAP 조정에 따른 수익성이 감소할수록 외국인투자가 증가하는 결과는 외국인이 현재의 이익보다는 미래의 예상되는 이익에 더 비중을 두고 투자결정을 한다는 것을 보여준다.

기관지에 발생한 선양 낭성암종의 세포학적 소견 - 1례 보고 -

이지신,김종순,양복숙,이민철,박창수,정상우,Lee, Ji-Shin,Kim, Jong-Soon,Yang, Bok-Sook,Lee, Min-Cheol,Park, Chang-Soo,Juhng, Sang-Woo 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.1

Adenoid cystic carcinoma arising from the submucosal glands of the trachea and bronchial tree is rare. The histopathology and natural history of bronchial adenoid cystic carcinoma have been well documented, but detailed descriptions of its cytomorphology are few. We report a case of primary bronchial adenoid cystic carcinoma in a 20-year-old female, diagnosed by bronchial brushing cytology. The cytologic specimens showed large clusters of small cells arranged around cystlike spaces containing globular basophilic material.

갑상선 역형성암종의 DNA 배수성에 관한 화상분석학적 연구

이지신,이민철,박창수,정상우,Lee, Ji-Shin,Lee, Min-Cheol,Park, Chang-Soo,Juhng, Sang-Woo 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.1

Anaplastic carcinoma of the thyroid gland is one of the most malignant tumors. Recently, DNA ploidy measured by flow cytometry and image analysis has been suggested as an additional useful indicator of tumor behavior. Studies on the occurrence and clinical significance of DNA aneuploidy in anaplastic carcinoma of the thyroid are rare. In this study, the pattern of DNA ploidy was measured by image analysis on Papanicolaou stained slides in four cases of anaplastic carcinoma and also measured by flow cytometry using paraffin blocks in two cases. In all cases of anaplastic carcinoma, DNA aneuploidy was found by image analaysis. By flow cytometry, one case had a diploid peak and the other case had an aneuploid peak. According to the above results, we conclude that anaplastic carcinoma of the thyroid glands have a high incidence of DNA aneuploidy and image analysis using Papanicolaou stained slides is a useful method in detecting DNA aneuploidy.

자궁에 발생한 지방평활근종 1 례

이지신,신승권,최호준,양해관,이명재,윤길팔 대한산부인과학회 1995 Obstetrics & Gynecology Science Vol.38 No.7

저자들은 본 성골롬반병원 산부인과에서 자궁 전적출술을 시행하여 확진한 자궁에 발생한 지방평활근종 1예를 경험하였기에 증례보고와 아울러 문헌고찰하는 바이다. Lipoleiomyomas of the uterus are extremely rare and have little attention. They have aroused interest as a consequence of occasional diagnostic confusion with sarcomas and the continuing unresolved dispute for their histogenesis. We experienced a case of lipoleiomyoma of the uterus, so reported with a brief review of the literature and pahologic findings.

세침흡인 생검으로 진단된 안와 수막종 - 1예 보고 -

이지신,김경수,이민철,박창수,정상우,Lee, Ji-Shin,Kim, Kyung-Soo,Lee, Min-Cheol,Park, Chang-Soo,Juhng, Sang-Woo 대한세포병리학회 1994 대한세포병리학회지 Vol.5 No.2

Orbital meningioma is a rare neoplasm that, even when suspected by CT or echographic examination, requires careful histologic study for precise identification. Fine needle aspiration(FNA) biopsy has become the diagnostic technique of choice in recent years for investigating orbital masses. There have been a few previous reports on FNA biopsy of orbital menigioma. We experienced a case of orbital meningioma in a 11-yr-old boy, diagnosed by FNA biopsy. The cytohistologic features of aspirated material (intranuclear inclusions, psammoma bodies, and cells arranged in whorls) made it easy to diagnose a meningloma.

파골세포 모양의 다핵거대세포를 지닌 갑상선 역행성암종의 세침흡인 세포학적 소견

이지신,고향미,이민철,박창수,정상우,Lee, Ji-Shin,Ko, Hyang-Mi,Lee, Min-Cheol,Park, Chang-Soo,Juhng, Sang-Woo 대한세포병리학회 1994 대한세포병리학회지 Vol.5 No.2

Anaplastic carcinoma of the thyroid is one of the most malignant tumors and survival for longer than three years after diagnosis is exceptional. Multinucleated giant cells of osteoclastlike appearance are seen un some of the anaplastic carcinoma, but only three cases in which the diagnosis was made by fine needle aspiration (FNA) cytology are reported in the international literature. We experienced a case of anaplastic carcinoma with osteoclastlike giant cells in a 66-yr-old female, diagnosed by FNA cytology. The smears revealed two cell populations: multinucleated giant cells and large polygonal or spindle shaped malignant cells. The FNA cytodiagnosis of anaplastic thyroid carcinoma containing osteoclastlike giant cells was substantiated by subsequent biopsy.

체강삼출액의 진단에 있어서 p53 단백의 유용성

이지신,박창수,Lee, Ji-Shin,Park, Chang-Soo 대한세포병리학회 1996 대한세포병리학회지 Vol.7 No.2

The diagnostic accuracy of routine cytological preparations from effusions ranges from 60% to 70%. Immunohistochemical markers, especially tumor-associated antigens, have been successfully employed to increase diagnostic sensitivity in effusion cytology. However, more than two different antibodies in diagnosis of effusions are needed. In the view of prevalence of abnormalities of p53 gene in human malignancies we investigated the diagnostic usefulness of demonstration of p53 protein immunoreactivity in distinguishing benign changes versus malignant processes in effusions. p53 protein expression was studied immunohistochemically in 76 effusions(28 malignant and 48 benign) using anti-human p53 antibody p53 immunoreactivity was identified in 19 of 28(67.9%) malignant effusions. In contrast, no p53 immunoreactivity was observed in all benign effusions. A specificity of 100% and a sensitivity of 67.9% were observed. These results suggest that immunohistochemical detection of p53 protein seems to be helpful in distinguishing benign changes versus malignant processes in effusions, although its principal limitation is its relatively low sensitivity.

유방의 낭성샘근육상피종 -1예 보고-

이지신,최명숙 대한병리학회 2003 Journal of Pathology and Translational Medicine Vol.37 No.2

Adenomyoepithelioma of the female breast is a rare tumor. With rare exceptions, the tumor is uniformly solid. We describe a large grossly cystic adenomyoepithelioma in a 67-year-old female. The tumor was histologically benign. The characteristic microscopic finding was the proliferation of rounded tubules lined by both epithelial and myoepithelial cells. Immunohistochemical findings confirmed the presence of two cell population.