J.P.Hebel의 단편 'Unvergofftes Wiedersehen'에 대한 텍스트 언어학적 고찰

오보영 陸軍士官學校 1994 한국군사학논집 Vol.47 No.-

신선편의식품 중 샐러드 제품의 영양성분 분석 연구

오보영,예민지,김종수,이혜영,방수진 한국식품영양과학회 2020 한국식품영양과학회 학술대회발표집 Vol.2020 No.10

커피음용행동의 의미에 대한 대학생의 개념도 분석

오보영,이상희 한국감성과학회 2016 춘계학술대회 Vol.2016 No.-

면역친화성 컬럼을 이용한 특수용도식품 중 비타민B 12 와 비오틴 분석 연구

오보영,예민지,허수정,이혜영,방수진 한국식품위생안전성학회 2020 한국식품위생안전성학회지 Vol.35 No.3

This study was conducted to improve the standard method for vitamin B 12 and biotin contained in foods for special dietary uses to ensure the specificity of the complex matrix properties of foods. For the food code, the test method was improved to determine vitamin B 12 and biotin by high-performance liquid chromatography (HPLC)-UV using columnswitching after concentration using immunoaffinity column. The immunoaffinity columns contain a gel suspension of monoclonal antibody specific to the vitamin of interest so that it can be used to concentrate the vitamin B 12 and biotin and remove interferences from the food extracts. Moreover, validation of advanced new methods was carried out to support the suitability of the proposed analytical procedure (specificity, linearity, detection limits (LOD), quantitative limits (LOQ), accuracy, and precision). The improved analytical method is being used to monitor relevant food items on sale. The results of this study showed that the new analytical method is suitable and appropriate for managing food intended for special dietary uses.

결착제 조성이 견과-깨 엿강정의 저장 중 지방질 산화와산화방지제 안정성에 미치는 영향

오보영,신말식,최은옥 한국식품과학회 2018 한국식품과학회지 Vol.50 No.3

Lipid oxidation and antioxidant stabilities of nut-sesame yeotgangjeong (Korean traditional candy bar) with different binders were evaluated during storage in the dark. S1, S2, and S3 binders consisted of starch syrup, sugar, and water (58:34:7.6, w/w/w); starch syrup, jocheong, honey, trehalose, and water (43.5:11.6:2.9:34:7.6, w/w/w/w/w); and starch syrup, jocheong, honey, sugar, trehalose, and water (43.5:11.6:2.9:17:17:7.6, w/w/w/w/w/w); respectively. Lipid oxidation was determined by peroxide and p-anisidine values, and tocopherol, lignan, and polyphenol contents were determined spectrophotometrically. Peroxide values were significantly higher (p<0.05) in yeotgangjeong samples with S2 or S3 binder than in those with S1; however, the converse was true for tocopherol degradation. Lignan was the most stable antioxidant in yeotgangjeong. The results suggest that tocopherols have a priority over lignans to control the lipid oxidation of yeotgangjeong during storage; reduced lipid oxidative stability after substituting sugar with trehalose might be because it increases oxygen diffusivity and inhibits the antioxidant action of tocopherols on lipids.

통합적 다이어트 유형 척도의 개발 및 타당화 연구

오보영,이상희 한국식공간학회 2022 식공간연구 Vol.17 No.1

This study was designed to identify the diet components that are becoming of great importance in modern society and to develop an integrated diet evaluation scale. The 132 pilot questionnaires were developed by literature review and interviews of diet experiencers, and experts evaluated those questionnaires. Preliminary research was conducted with 317 diet experiencers by a research firm, then 23 items of four factors were selected through exploratory factor analysis. Four factors were identified: positive emotion, negative emotion, social appearance pressure, and diet behaviors. Moreover, the questionnaire was sent to 397 diet experiencers to examine the scale validity. Responses were analyzed by confirmatory factor analysis, which found the four-factor with 23 items well-represented characteristics of the integrated diet evaluation scale. Finally, the integrated diet evaluation scale significantly correlated with eating cognitive distortion, food craving, social imposition perfectionism, diet efficacy, self-esteem, depression, and perceived stress. Finally, discussions were made around limitations of the present study and suggestions for future research that should be conducted to classify diet types by using the developed scale.

Epidermal Growth Factor Receptor Mutations in Colorectal Cancer Patients

오보영,이령아,정순섭,김광호 대한대장항문학회 2011 Annals of Coloproctolgy Vol.27 No.3

Purpose: The epidermal growth factor receptor (EGFR) plays an important role in tumorigenesis and tumor progression of colorectal cancer and leads to the activation of intracellular signaling pathways. The use of anti-EGFR-targeted therapy has increased for patients with colorectal cancer, but patients with EGFR mutations will be resistant to anti-EGFR-targeted therapy. The identification of gene mutations is critical in cancer treatment; therefore, the aim of this study is to investigate the incidences of EGFR mutations in colorectal cancer patients in Korea. Methods: We retrospectively reviewed 58 colorectal cancer patients who underwent surgery between 2003 and 2006. We analyzed their EGFR mutations in four loci by DNA sequencing. In addition, we analyzed the correlation between the presence of EGFR mutation and patients’ clinicopathologic features. Results: Of the 58 patients, 35 patients were male and 23 were female. Their mean age was 63.28 ± 11.18 years. Two patients (3.45%) were diagnosed as stage Tis, 7 patients (12.07%) as stage I, 24 patients (41.38%) as stage II, 20 patients (34.48%) as stage III, and 5 patients (8.62%) as stage IV. As a result of mutational analysis, EGFR mutations on exon 20 were detected in 13 patients (22.41%, G→A transitions). No EGFR mutations were detected on exons 18, 19, and 21. EGFR mutation was increased in the earlier stage and in the absence of lymph node metastasis (P = 0.028). Conclusion: The incidence of EGFR mutation in Korean colorectal cancer patients is 22.41%. In addition, EGFR mutation was significantly increased in the earlier stage and in the absence of lymph node metastasis.

Advances in surgery for locally advanced rectal cancer

오보영 대한대장항문학회 2022 Annals of Coloproctolgy Vol.38 No.4

암을 이기는 채식 밥상

오보영,노경태,이령아,김광호 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.1

Cancer prevention by vegetable diet has received considerable attention in recent years. In the past these attributes of vegetables were based more on beliefs than on scientific evidences. But over the past few decades many studies have been performed about that. Cancer preventive components of many vegetables have been studied in experimental carcinogenesis models. These studies have reported on these components influence carcinogenesis during initiation and promotion phases of cancer development. Also, epidemiological studies and clinical trials have reported cancer preventive effects of vegetables. However, there is no comprehensive summary of cancer preventive effects with the types of vegetables. In this review, we classified the vegetables and described the mechanism of action of active components of vegetables, experimental studies, and clinical trials. Results revealed a negative correlation between consumption of vegetables and cancer risk. But we can’t still conclude the effects of vegetables yet, so further studies would be necessary for final conclusion.

면역친화성 컬럼을 이용한 특수용도식품 중 비타민B₁₂와 비오틴 분석 연구

오보영,예민지,허수정,이혜영,방수진,Oh, Bo-Young,Ye, Min-Ji,Hu, Soo-Jung,Lee, Hye-Young,Bang, Soo-Jin 한국식품위생안전성학회 2020 한국식품위생안전성학회지 Vol.35 No.3

본 연구는 특수용도식품에 함유되어 있는 비타민B₁₂와 비오틴에 대하여 식품의 복잡한 매질 특성에 특이성을 확보할 수 있도록 현행 식품공전 시험법을 개선하고자 하였다. 식품공전에서 비타민B₁₂와 비오틴의 시험법에 항체반응을 통해서 분석물질과 특이적으로 결합하여 그 외의 성분들을 효과적으로 제거할 수 있는 면역친화성 컬럼을 도입하여 시험용액을 정제 및 농축함으로써 전처리 과정을 개선하였다. 식품 등 시험법 마련 표준절차에 관한 가이드라인에 따라 밸리데이션(특이성, 직선성, 검출한계, 정량한계, 정확도, 정밀도)을 수행하고 개선된 시험법을 이용하여 유통 중인 특수용도식품의 대상 품목에 대해 시험법 적용여부를 확인하였다. 본 연구사업의 수행으로 시험·검사의 정확성을 증대시켜 특수용도식품 품질관리에 대한 신뢰성을 더 높일 것으로 본다. This study was conducted to improve the standard method for vitamin B₁₂ and biotin contained in foods for special dietary uses to ensure the specificity of the complex matrix properties of foods. For the food code, the test method was improved to determine vitamin B₁₂ and biotin by high-performance liquid chromatography (HPLC)-UV using column-switching after concentration using immunoaffinity column. The immunoaffinity columns contain a gel suspension of monoclonal antibody specific to the vitamin of interest so that it can be used to concentrate the vitamin B₁₂ and biotin and remove interferences from the food extracts. Moreover, validation of advanced new methods was carried out to support the suitability of the proposed analytical procedure (specificity, linearity, detection limits (LOD), quantitative limits (LOQ), accuracy, and precision). The improved analytical method is being used to monitor relevant food items on sale. The results of this study showed that the new analytical method is suitable and appropriate for managing food intended for special dietary uses.