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송정은,김영신,Bennett L. Leventhal,고윤주,천근아,홍현주,김영기,조경진,임은정,박지인 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.2
Purpose: Our study aimed to examine psychometric properties and cross-cultural utility of the Behavior Assessment System for Children-2, Parent Rating Scale-Child (BASC-2 PRS-C) in Korean children. Materials and Methods: Two study populations were recruited: a general population sample (n=2115) of 1st to 6th graders from 16 elementary schools and a clinical population (n=219) of 6–12 years old from 5 child psychiatric clinics and an epidemiological sampleof autism spectrum disorder. We assessed the validity and reliability of the Korean version of BASC-2 PRS-C (K-BASC-2 PRS-C) and compared subscales with those used for US populations. Results: Our results indicate that the K-BASC-2 PRS-C is a valuable instrument with reliability and validity for measuring developmentalpsychopathology that is comparable to those in Western population. However, there were some differences noted in the mean scores of BASC-2 PRS-C between Korean and US populations. Conclusion: K-BASC-2 PRS-C is an effective and useful instrument with psychometric properties that permits measurement of generaldevelopmental psychopathology. Observed Korean-US differences in patterns of parental reports of children’s behaviors indicatethe importance of the validation, standardization and cultural adaptation for tools assessing psychopathology especially when used in populations different from those for which the instrument was originally created.
Recurrent thymic carcinoid tumor in familial isolated primary hyperparathyroidism
송정은,손무현,김가영,이다영,이정훈,김종호,손호상,이지현,전언주,정의달 영남대학교 의과대학 2014 Yeungnam University Journal of Medicine Vol.31 No.2
Familial isolated primary hyperparathyroidism(FIPH) is associated with multiple endocrine neoplasia type 1 (MEN1) syndrome, primary hyperparathyroidism accompanied by jaw-tumor syndrome, and familial hypocalciuric hypercalcemia. FIPH may be an early stage of MEN1 or an allelic variant of MEN1. Thymic carcinoid tumor is a rare tumor in MEN1 syndrome. Here, the authors report the case of a 40-year-old man diagnosed with recurrent thymic carcinoid tumor and FIPH. Both the patient and his elder sister had been previously diagnosed to have FIPH with a novel frameshift mutation in the MEN1 gene. Initially, the patient underwent thymectomy because of an incidental finding of a mediastinal mass in his chest X-ray, and had remained asymptomatic over the following 4 years. Pancreas computed tomography conducted to evaluate MEN1 syndrome revealed anterior and middle mediastinal masses, and resultantly, massive mass excision was performed. Histological findings disclosed atypical carcinoids with infiltrative margins. In view of the thymic carcinoid tumor relapse that occurred in this patient, the authors recommend that regular pancreas and pituitary imaging studies be conducted for FIPH associated with a MEN1 gene mutation.
Endoscopic Therapy and Radiologic Intervention of Acute Gastroesophageal Variceal Bleeding
송정은,Byung Seok Kim 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.5
Acute gastroesophageal variceal hemorrhage is a dreaded complication in patients with liver cirrhosis. Endoscopic therapy andradiologic intervention for gastroesophageal bleeding have rapidly developed in the recent decades. Endoscopic treatment is initiallyperformed to stop variceal hemorrhage. For the treatment of esophageal variceal bleeding, endoscopic variceal ligation (EVL) isconsidered the endoscopic treatment of choice. In cases of gastric variceal hemorrhage, the type of gastric varices (GVs) is importantin deciding the strategy of endoscopic treatment. Endoscopic variceal obturation (EVO) is recommended for fundal variceal bleeding. For the management of gastroesophageal varix type 1 bleeding, both EVO and EVL are available treatment options; however, EVOis preferred over EVL. If endoscopic management fails to control variceal hemorrhage, radiologic interventional modalities could beconsidered. Transjugular intrahepatic portosystemic shunt is a good option for rescue treatment in refractory variceal bleeding. In casesof refractory hemorrhage of GVs in patients with a gastrorenal shunt, balloon-occluded retrograde transvenous obliteration could beconsidered as a salvage treatment.