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      • SCOPUSKCI등재

        톨루엔 취급자들의 면역기능에 관한 조사

        서석권,이종영,이승훈,Suh, Suk-Kwon,Lee, Jong-Young,Lee, Seoung-Hoon 대한예방의학회 1992 예방의학회지 Vol.25 No.2

        톨루엔의 폭로가 인체의 면역기능에 미치는 영향에 대해 알아 보기 위하여 톨루엔 취급자 21명과 일반 사무직 근로자 12명에 대하여 혈액 및 말초혈액 림프구의 subpopulation에 대하여 조사하였다. 혈액소견은 두 군 모두 정상범위로 통계적으로 유의한 차이가 없었다. CD4 림프구 세포의 비율은 두 군에서 유사하였으며 T와 B림프구 및 CD8 림프구 세포의 비율은 폭로군에서 약간 낮았으나, 두 군 모두 정상 범위로 통계적으로 유의한 차이가 없었다. 폭로군에서 T 림프구 및 CD4 세포의 비율은 근무기간이 길수록 통계적으로 유의하게 증가하였다(P<0.05). 본 연구의 폭로군에서 림프구의 subpopulation은 전반적으로 비폭로군보다 약간 낮은 경향은 있었지만, 정상범위에 해당하였으므로 톨루엔에 폭로되었을 때 인체에 대한 면역기능은 큰 영향이 없는 것으로 생각되어진다. 그러나 폭로기간에 따라 면역기능이 변동하는 것으로 보아 톨루엔이 인체의 면역기능에 미치는 영향에 관한 지속적인 연구가 이루어져야 하겠다. To assess the immunological function of toluene exposed group, the proportions of T lymphocyte, B lymphocyte, CD4 cell, CD8 cell, the ratio of CD4 to CD8(CD4/CD8) in peripheral blood were measured on twenty-one toluene exposed workers and twelve healthy workers who did not have previous history of toluene exposure. In addition, to evaluate the present status of toluene exposure, urinary hippuric acid concenturations were measured in exposed group. The mean concenturation of urinary hippuric acid was 2.84 g/creatinine g in exposed group. The proportions of T lymphocyte, B lymphocyte, CD8 cell and CD4/CD8 of exposed group were slightly lower than non-exposed group except the proportion of CD4 cell which was similar in both groups. But these differences were not statistically different in both groups. The proportions of T lymphocyte and CD4 cell were significantly correlated with the length of duration in exposed group(P<0.05).

      • KCI등재

        농업종사자(農業從事者)의 혈장(血漿) Cholinesterase 치(値) 변화(變化)에 관(關)한 연구(硏究)

        서석권,황인담,Suh, Suk-Kweon,Hwang, In-Dam 한국농촌의학지역보건학회 1983 농촌의학·지역보건 Vol.8 No.1

        살충제(殺蟲劑)의 주종(主宗)을 이루는 유기인제(有機憐劑)에 의한 만성중독(慢性中毒)의 예방(豫防)을 위(爲)한 기초자료(基礎資料)를 얻고, 또한 농업종사자(農業從事者)의 혈장(血漿) cholinesterase의 정상치(正常植)를 추정(推定)하고저 전라북도(全羅北道) 정읍군(井邑郡)의 일부(一部) 농업종사자(農業從事者)에 대(對)한 혈장(血漿) cholinesterase 치(植)를 Takahashi의 Micro- method로 측정분석(測定分析)한바 다음과 같이 요약(要約)된다. 1) 농약살포전군(農藥澈布前群)의 혈장(血漿) cholinesterase 치(植)는 $7.60{\pm}1.74{\mu}M/20{\mu}{\ell}$/hr.였고, 살포후군(撒布後群)에서는 $6.23{\pm}1.59{\mu}/20{\mu}{\ell}$/hr.로서 살포전군(澈布前群)보다 $1.37{\mu}M/20{\mu}{\ell}$/hr.가 낮게 나타났다 (P < 0.01). 2) 농업종사자(農業從事者)의 정상(正常) 혈장(血漿) cholinesterase 치(植)의 95% 신뢰구간(信賴區間)은 $7.30-7.90{\mu}M/20{\mu}{\ell}$/hr.이었다. This study was carried out to obtain the basic data for the prevention of chronic poisoning by organic phosphorous pesticides and to estimate the normal range of plasma cholinesterase activity level for Korean agricultural workers. The 285 agricultural workers were randomly selected for the study in Jungup Gun, Jeonbug Province, 135 persons of them were tested in the period of pre-exposure of organophosphorous pesticides (April 1981) and rest of them were tested after exposure(August 1981). Cholinesterase activity levels were measured by the Micro-method of Takahashi Hiroshi. Major findings are as following: 1) There is significant difference in plasma cholinesterase activity levels between the pro-exposed and post exposed group(p > 0.01). Mean values of plasma cholinesterase activity levels were $7.60{\pm}1.74{\mu}M/20{\mu}{\ell}$/hr. in the pre-exposed group and $6.23{\pm}1.59{\mu}M/20{\mu}{\ell}$/hr. in the post-exposed group. 2) Plasma cholinesterase activity in Korean agricultural worker could be estimated $7.30-7.90{\mu}M/20{\mu}{\ell}$/hr. with 95% confidence interval.

      • KCI등재후보

        SJAS로 측정한 A 형행동양상과 사회인구학적인 변수

        서석권 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2

        To investigate the sociodemographic variables to enhance and maintain the Type A behavior Pattern (TABP) socially by comparing the differences of sociodemographic variables of the A-B Behavior Pattern measured by the Student Jekins Sctivity Survey(SJAS, short form), the authors conducted a questionnaire survey using a medical school undergraduated(413) as a study population April to May, 1988. The cut-off point which divides into A-B Behavior Pattern was ±1 standard deviation of the total score of the SJAS(≤3, ≥10), resulting in 61 TABP & 82 Type B Behavior Pattern (TBBP). The reliability coefficient of the total score of the SJAS measured by Cronbach's alpha was 0.72. In the family environments, there were no difference in the place raised, deceased father, age of father between TABP and TBBP. The Hollingshead's socioeconomic status index which was dichotomized by median value showed a statistically significant difference; The high index group was 47.4% in TABP and 65.8% in TBBP(P=0.03). TABP showed little difference in age, sex, and proportion of those who have a religion compared with the TBBP. The proportion of those who suffered a failure more than once academically after entering the medical school was 19.7% in TABP and 35.4 in TBBP which was statistically significant(P=0.04). TABP was not different from TBBP in the habits of smoking and alcohol consumptions. The smaller proportion of failure suffered in TABP than TBBP could explain the competitive and hard-driving aspects of the TABP and the socioeconomic status may exert a different influence on the socialization pressure leading to the formation of the TABP in the early life from the American's.

      • KCI등재후보

        職場 身體檢査에서 본 肥滿에 關한 硏究

        尹能基,徐錫權 啓明大學校 醫科大學 1985 계명의대학술지 Vol.4 No.2

        1. 全 調査者를 통한 肥滿率은 男子 9.0%, 女子 5.2%(男女7.8%), 過體重率은 男子 19.2%, 女子 15.5%로 男女 모두 女子보다 男子가 높았다. 2. 全 調査者를 통한 男子의 年齡別 肥滿率은 20代 4.6%, 30代 10.7%, 40代 13.3%, 50代 26.1% 過體重率은 20代 11.3%, 30代 23.0%, 40代 27.7%, 50代 30.4%로 年齡의 增加에 따라 肥滿率, 過體重率 함께 增加하고 있다. 全 女子對象中 96.4%를 占하고 있는 20代에서 肥滿率 4.1%, 過體重率 15.5%로 나타났다. 3. 部署別 男子 肥滿者는 雜役職 12.8%, 管理職 11.4%, 事務職 6.8%, 現金出納職 4.8%이고 過體重者는 雜役 25.0%, 管理職 22.9%, 事務職 15.4%, 現金出納職 14.9%로 肥滿率과 過體重率 共히 같은 部署別로 高位 順位를 보였다. 女子 肥滿者는 現金出納 6.2%, 職事務 2.3%, 職過體重者는 現金出納職 16.1%, 事務職 14.5%로 거의 같은 率을 보였으며 女子에 있어서는 現金出納職과 事務職에 密集되어 있어 他 部署別과의 比較는 되지 않았다. 4. 全 調査者를 통한 勤務年數別 肥滿度率은 5年以下 6.4%, 6~9年 7.4%, 10~14年 7.5%, 15年~19年 12.7%, 20年以上 21.9%, 過體重率은 5年以下 14.3%, 6~9年 7.4%, 10~14年 7.5%, 15~19年 12.7%, 20年以上 21.9%로 肥滿率과 過體重率이 平行된 增加 樣相을 보이고 있다. 5. 肥滿度率과 高血壓値 및 血色素値 level의 增加와는 一定한 關聯性이 없었다. Studies on obesity of bank personnel were carried out and the following results were obtained. 1. Incidences of obesity (according to Broca criteria) in 1694 cases (1172 male, 522 female) showed 9.0% in males, 5.2% in females and 7.8% in both sexes. 2. The percentage of obesity in males increased as age increased as follows: 4.6%, 20 to 29 years; 10.7%, 30 to 39 years; 13.3%, 40 to 49 years; and 26.1%, 50-59 years. In females (503 cases) in the 20 to 29 years old range, 4.1% were found to be obesity. In the 30 to 59 years range, the number of cases was too small to make a comparison. 3. In management, the obesity rate in males of 11.4% was higher than in other positions except for miscellaneous, labor type jobs. In female groups, accounting had 6.2% and business had 2.3% obesity rate. 4. The obesity rate in both sexes inceased as the number of working years increased, as follow; 6.4% under 5 years, 7.4%, 6 to 9 years; 7.5%, 10 to 14 years; 12.7%, 15 to 19 years and 21.9%, 20 years and over. 5. A uniform relation between obesity, blood pressure, and hemoglobin was not found.

      • KCI등재후보

        John Henryism과 혈압

        이충원,서석권 啓明大學校 醫科大學 1989 계명의대학술지 Vol.8 No.2

        The Hypothesis was tested that the John Henryism would be associated with blood pressure and it would have interaction with stress-coping resources on the blood pressure measured by the Perceiived Social Support Scales(PSSS) in 168 persons undergoing the preemployment examinations comprised of 83 males and 85 females(mean age 19.4, S.D. 3.13), November 1988. The John Henryism Scales for Active Coping(JHAC12) was distributed normally with mean 45.6, standard deviation 6.2, median 4445, and range 26-59. The reliability coefficients was 0.79 for both sexes. The factor analysis yielded 3 factors which was extracted by principal component analysis. The main effect of social support on John Henryism was statistically significant(P=0.00), and interaction effect of sex and social support was significant also(P=0.02) and that of age and social support marginally(P=0.08). The main effect of John Henryism on blood pressure was negligible in both sexes but after adjusting for amounts of smoking and alcohal intake it became statistically significant(P=0.05) in male diastolic blood pressure. Men showed no interaction of John Henryism with social support. Among women, however, there was interaction with borderline significance(P=0.04) in diastolic blood pressure without any significant interaction. But the direction of the interaction supported the hypothesis. These results suggest that the interactions of John Henryism with stress-coping resoources on blood pressure may be present in socioeconomic-cultural settings other than American blacks' which were envisioned originally.

      • KCI등재후보

        K 대학병원 서어비스에 대한 소비자 만족도

        이태섭,박종원,이무식,윤능기,이충원,서석권 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

        Authors administered a questionnaire to 300 clients visited to the K University Hospital during August in 1992 to investigate the degree and related factors of consumer's satisfaction with the hospital services. Clients consisted of 82 in-patients and 158 out-patients, 52.4 percent of them was male. Four dimensions of satisfaction were assessed which were medical management, administration, environment and attitude. In-patients reported as dissatisfied with the waiting time during receipt, investigative medical procedures and pharmacy (64.7%), lack of conveniency facilities for patients and their guardians(48.8%) and provision of conveniency facilities in the ward(42.4%), unsanitary state of out- and in-hospital(41.5%). Out-patients reported dissatisfaction with the course of medical management and the time needed(70.3%), the waiting time during receipt, investigative medical procedures and pharmacy(68.3%), lack of conveniency facilities for patients and guardians(42.4%). But both in-patients and out-patients were satisfied with medical equipments, doctor's diagnosis reliability and medical effects, technician's attitude more than 50%. Canonical correlation analysis was done to find related sociodemographic factors to the four dimensions of satisfaction. Of the four canonical functions, the first was only statistically significant in in-patients. Its eigen value was 0.56 and its canonical correlation coefficient was 0.60. Satisfaction with environment and medical management was selected as important concept in dependent variables. Standardized canonical function of environment and medical management were 0.76 and 0.35 respectively. It was related with woman with high educational attainment and increasing number of hospital visits. In out-patients, the first, second and third function were statistically significant and their eigen values were 0.18, 0.4, 0.08 respectively which were small compared to those of in-patients. Their canonical correlation coefficient were 0.40, 0.35, 0.28 respectively. Low degree of environment but high degree of medical management satisfaction was noted in the first function which was related with old age, woman and professional occupation. Low degree of satisfaction with administration(second function) was related with city resident, non-professional occupation and young age. High degree of medical management but low degree of administration satisfaction(third function) was related with surgical visitor, man and non-professional occupation. The direction of hospital managerial strategies could be planned and general characteristics of dissatisfactory clients might be suggested with these results.

      • KCI등재후보

        대구시 모 보건소에 내소한 성병환자에 대한 연구

        윤능기,서석권 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2

        The authors selected the medical records of the 2,346 diagnosed urethritis and syphilis patients from those who visited to a public health center in Taegue City, 1, January 1985 to 31, December 1987 to treat their urologic symptoms. Their medical records were used to investigate distribution status of the infection by demorgaphic and temporal variables. The results were as follows: 1. The most frequent age group was 20-29 years of age, 65.6%, and the less than 20 years of age group was 10.2%. In 30-39 age group, males 17.9% and females 23.0% and in 40-49 group, males 4.5% and females 12.2%. The female excess prevalence remained the same after that age group. 2. The order of relative frequency of the infection by month in which 3-year cases were combined was August, 11.3%, July 10.9%, January, 10.3% and the monthly distribution of the student was August, 16.0%, January, 11.6%, March, 10.7%, which suggests a coincidence with the periods of the school vacations. The seasonal distribution was summer 31.2%, spring 25.5%, autumn 21.7%, winter 21.5%. 3. The relative frequency of infection by martial status showed the unmarried was 70.3% and the married 29.37%, which was a significant difference. 4. The distribution by occupation was merchants 25.5%, office workers 19.2% and students 15.5% which was unexpectedly high. 5. In the distribution by source of infection of the males, friends was the most frequent source with 28.7%, restaurant employees 25.2%, prostitutes 16.8%, prostitutes 16.8%, and employees of lodging service 12.4%. 6. In the distribution by age and source of infection, friends were the most frequent source of infection(63.1%) in the less than 20 years of age group. In 20-29 years of age group, friends were 28.6%, restaurant employees 24.5%, prostitutes 17.8%, where showed increasing proportions of employees of the service trade. In 30-39 years of age group, restaurants employees 35.9%, employees of the lodging service 15.9%, prostitutes 14.9%, which means that most of sources of infection were employees of the service trade. In 4.-49 years of age group, restaurant employees 39.7%, prostitutes 17.2% and in 50-59 group, spouse was the most frequent(27.3%) and in the more than 60 years of age group prostitutes was 50%, but the total cases of that age group were too small to tabulate meaningfully. 7. The relative frequency of infection by infection history showed the inexperienced ws 48.4% and the experienced 51.6% and in the inexperienced, males 47.9% and females 78.1%.

      • KCI등재후보

        농촌 노인에서의 농부증과 우울정도와의 관련성

        서석권,양선희,이미영,신동훈,이무식 啓明大學校 醫科大學 1998 계명의대학술지 Vol.17 No.3

        농부증은 그 자체로서 하나의 질병은 아니나, 우리 나라 농촌 지역에서 농부증의 유병율이 20∼40%에 이르는 것으로 보고되면서, 농부증의 원인에 대한 여려 조사 연구가 있어 왔다. 과거에는 농부증이 농촌 지역에 국한되어 발생하는 특수한 농부들의 질환이라고 하였으나 최근에는 농부증의 원인으로는 스트레스가 지목되고 있으며, 정신적인 스트레스가 증가할수록 농부증의 위험도 증가되는 것을 h보고되고 잇다. 이에 본 연구는 경상북도 김천시 조마면에 거주하는 60세 이상의 농업협동조합 조합원 및 그 가족을 대상으로 농부증에 영항을 주는 요인 및 농부증과 우울 성향과의 관련성을 밝혀 보고자 하였다. 60세 이상을 대상으로 한 본 연구의 결과에서 농부증에 영향을 주는 요인으로는 성별과 우울 성향 뿐이었으며, 성별보다는 우울 성향이 더 큰 영향을 미치는 것으로 평가되었다. 또 한 농부증의 가장 빈도가 높은 증상인 요통, 손발저림, 어깨결림 중 어깨결림, 요통이 우울 성향과 유의한 관련을 보여주었으며, 그 외 농부증의 증상 중 호흡곤란과 어지러움이 우울 성향과 밀접한 상관관계를 가지는 것으로 나타났다. 따라서, 본 연구결과는 농부증에 영향을 미치는 요인으로 성별을 제외하면 우울 성향뿐이며, 농부증의 증상 항목 중에서 네 가지 항목이 우울성향과 밀접한 관련성이 있음을 보여줌으로서 농부증이 농촌 지역에 국한된 특수한 질환이라기보다는 정신적 우울 성향에 의한 복합적인 증상일 가능성을 제시해 준다. Farmers' syndrome is so important health problem of rural areas in recent years. The study was conducted to elucidate the relationship between farmer's syndrome and the depth level of depression in rural elderly. This study was done in the selected 4 villages in Kimchun County of Kyungbuk Province. The subject was the resident that 202 adults above 60 years of age. The Questionnaire of interview included sociodemographic data, 8 components of farmer' syndrome and 21 items of Beck Depression Inventory(BDI). The data was interpreted by frequency analysis, chi-square test, t-test, oneway ANOVA, correlation analysis, and multiple regression. The results were as followed : 1. The total score of farmer's syndrome was evidently higher in the female elderly and the total BDI score was higher in small family size. 2. Among the eight symptoms of farmer's syndrome, lumbago, shoulder stiffness and numbness of limb were most common symptoms of farmer's syndrome. Among the most common three symptoms, two symptoms were related with BDI score tightly. 3. Except sex difference, farmer's syndrome was significantly correlated with BDI score and four symptoms had statistically significant relationship with BDI score. Therefore, depressions is most important cause of farmer's syndrome.

      • KCI등재후보

        일부 인쇄공들의 혈중 및 모발증 연함량

        서석권,윤능기 啓明大學校 醫科大學 1989 계명의대학술지 Vol.8 No.2

        For the purpose of obtaining on effective biological data, study to evaluate the health consequence of lead absorptioin was conducted using printing industry workers in Taegu City from July 1 to 31, 1989. The study population was the 64 lead-exposed workers and 31 non-exposed workers who were working in the printing industry. The lead indices subjected to this study were as follows;p blood lead(PbB0, Hemoglobin(Hb), lead in hair(PbH). Blood lead(PbB) and hair lead(PbH) concentrations were estimated using the Atomic Absorption Spectrophotometer(IL 551) equipped with furnace Atomizer(IL 755). The results obtain were as follows: The mean value of blood lead level were 25.58±7.21㎍/100ml and 22.95±4.80㎍/100ml in lead-exposed workers and controls, respectively and was statisically significant difference(p<0.05). The mean value of lead level in hair were 15.01±6.31㎍/g and 11.41±5.74㎍/g in lead-exposed workers and controls, respectively(p<0.01). The mean value of hemoglobin were 15.10±0.93 g/100ml and 14.67±1.03g/100ml in lead-exposed workers and controls, respectively(p<0.01). In lead-exposed workder, the correlation between PbB and PbH (r=0.0953), Hb(r=-0.2108) was no statistically significant difference, respectively and there was staatistically significant correlation between PbH and Hb (r=-0.3064), work duration(r=0.3658), respectively(p<0.01).

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