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침지형막분리법과 응집체첨가활성슬러지법의 조합에 의한 하수중의 유기물 및 인제거 특성에 관한 연구
박재로(Jae Roh Park),김응호(Eoung Ho Kim) 한국물환경학회 2000 한국물환경학회지 Vol.16 No.3
The objective of this research is to show whether Alum-MBR (Membrane Bio-Reactor) system is a technically feasible and economically competitive process for organic and phosphorus removal of municipal sewage. In Alum-MBR system, organic material and phosphorus are removed by biological, chemical reaction and membrane separation mechanism. The advantages of Alum-MBR system were listed as high treability, easy maintanance and automatic operation. Membrane used in this system was polyethylene hollow fiber microfiltration which surface treated hydrophilic with a pore size of 0.1㎛ and surface area of 4㎡ and two module was immersed to aeration basin of 0.4㎥. Jar test was conducted to find out weather chemicals are suitable for phosphorus removal and optimal dosage rate of chemicals and back-up test in a small-scale pilot plant was conducted to confirm of removal effect of organic material and phosphorus. The operation conditions of Alum-MBR system were fixed at suction-idle time of l0min-5min, permeation flux of 0.015㎥/㎡/hr, aeration intensity of 300ℓ/㎥/min. As the result of dosing Alum into MBR, flux was stable and permeate pressure was bring down remarkably. T-P concentration of permeated water always lower than target water quality of l㎎/ℓ.
2단형 막분리 활성슬러지법(Two Stage MBR)에서 내부순환을 변화와 응집제 첨가에 의한 질소 및 인제거 특성에 관한 연구
박재로 ( Jae Roh Park ),임현만 ( Hyun Man Lim ),김응호 ( Eoung Ho Kim ) 한국물환경학회 2002 한국물환경학회지 Vol.18 No.2
Laboratory-scale membrane bioreactor added alum into the anaerobic basin as a flocculant and adsorbent was carried out to find removal efficient of nitrogen and phosphorus components in the mixed liquid and weather or not maintaining the stability for the permeate flux and pressure at various internal recycle conditions. It was found that denitrification efficient of maximum 65% was obtained when the ratio of internal recycle was 3Q. Additionally when the ratio of internal recycle was fixed at 3Q, BOD_5 and T-P concentration of permeate was much more reduced compared to not added alum in anaerobic basin but T-N concentration of permeate was relatively increased. In case of added alum as the flocculant and adsorbent in anaerobic basin, the permeate flux was maintained above 10ℓ/㎡/hr but the permeate pressure was relatively higher than alum was not added in anaerobic basin.
2단형 막분리 활성슬러지법(Two Stage MBR)의 운전 특성에 관한 고찰
박재로 ( Jae Roh Park ),임현만 ( Hyun Man Lim ),김응호 ( Eoung Ho Kim ) 한국물환경학회 2002 한국물환경학회지 Vol.18 No.2
Two-stage membrane bioreactor using submerged hollow fiber membrane was applied in laboratory scale to treat nitrogen and phosphorus of domestic wastewater. Alum as the flocculant and adsorbent was added into the anaerobic basin of two-stage membrane bioreactor and mixed liquid of aerabic basin was recycled to the anaerobic basin for the purpose of nitrogen removal. Experiment was carried out to find removal efficient of phosphorous and nitrogen components in the mixed liquid, and the stability of the permeate flux and pressure of two-stage membrane bioreactor. In case of alum was added as the flocculant and adsorbent into the anaerobic basin, soluble phosphorus removal efficient was relatively higher and total permeate resistance (Rtot) was more increased out nitrogen removal efficient was lower as the result of lack of alkalinity and insufficient nitrification process than the case of alum was not added.
간암세포주를 대상으로 한 체외 복합 항암제 감수성 검사
박인서(In Suh Park),정재복(Jae Bock Chung),김병수(Byung Soo Kim),김주항(Joo Hang Kim),노재경(Jae Kyung Roh),유내춘(Nae Chun Yoo),조재용(Jae Yong Cho),최진혁(Jin Hyuk Choi),임호영(Ho Yeong Lim) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.2
N/A Primary hepatocellular carcinoma(HCC) is one of the most common malignancies in Korea due mainly to high incidence of chronic hepatitis B virus infection. Most of the HCC are inoperable even at first presentation. So chemotherapy could be one of the major therapeutic modalities, but HCC is seldom chemosensitive. This type of chemoresistance is explainesd by high level of expression of multidrug resistance(MDR) gene and p-glycoprotein. We initiated this study to establish the in vitro model of drug selection and combination for HCC. Three human HCC cell lines and five cytotoxic drugs were used. MTT assays for cytotoxicity test were performed with single chemotherapeutic agent and various two drug combinations. Slot blot analysis for measuring the expression levels or MDR1 RNA was performed and demon strated that 2 HCC lines show moderate to high degree of MDRI expression, The ranges of drug concetration which causes 50% inhibition of the cell lines(IC50) are in the clinically achievable concentrations for the 5-fluorouracil in two HCC lines, and adriamycin in one cell line. Two cell lines which showed positive MDRI exression were resistant to adriamycin. But all three cell lines were sensitive to etoposide irrespective of MDR1 expression. In thelinically achievable concentration ranges those we tested, singnificantly improved cytotoxic effects are demonstrated in combinations of etoposide plus cisplatin, and etoposide plus mitomycin-C out of 10 possible two drug combinations. These data indicate the need for in vivo trials with the combination chemotherapy of etoposide plus cisplatin or etoposide plus mitomycin-C for HCC.