GIS 를 이용한 도시환경 관리체계의 응용모형 개발에 관한 연구 : 대전시 서구를 중심으로

박영준 한남대학교 1998 국내석사

열 화학 기상 증착법에 의한 탄소나노튜브의 합성 및 전계방출 표시소자 응용

박영준 成均館大學校 大學院 2003 국내박사

Carbon nanotube (CNT) emitters have been fabricated for field emission displays (FEDs) by thermal chemical vapor deposition (thermal CVD), and their properties were investigated. The direct synthesis of CNTs on substrates by chemical vapor deposition is one of the highly promising routes for their application to FEDs. Several stringent requirements have to be met for this purpose, including low-temperature growth below 600°C to utilize glass substrates and large-area deposition for practical use. In this study, we carried out the synthesis of CNTs by thermal CVD on glass substrates at temperatures as low as 500 ~ 600°C. CNTs were grown by thermal decomposition of CO and H_(2) gases at an atmospheric pressure for different thicknesses of Invar (Fe-Ni-Co alloy) catalytic layers. Invar thin films were deposited by e-beam evaporation before the CNT growth. Using an array of Inavr film dots prepared by a photolithography process, patterned CNTs were grown on the Cr-coated glass substrates to characterize their field emission properties. The CNT growth was strongly correlated with the preparation condition of the catalytic layers. Prior to CNT synthesis, the Invar catalytic layers were annealed at different temperatures to change the crystal structures and morphologies in order to elucidate their effect on the growth of CNTs by rapid thermal annealing system. The crystal structures of catalyst were changed from the hexagonal phase to the cubic phase and resulted in larger grain sizes at higher temperatures by vacuum annealing. The CNT growth on vacuum-annealed catalyst layers showed the distinct morphological change of CNTs at the annealing temperature of 500°C. Images observed by high-resolution transmission electron microscopy showed the multedwalled structures of the nanotubes with Invar caps at their tips. The grain size of Invar thin films varied with the vacuum thermal treatment temperatures. It was found that the diameter, density, and degree of graphitization of CNTs could be systematically controlled by the grain size of Invar thin films. With reducing the grain size of Invar thin films, the diameter of nanotubes decreased, whereas the graphitization increased. These observations could be explained by growth mechanism proposed in the other researches. Such an evolvement of CNT morphologies seems to be attributed to grain size change rather than the crystal structure change with annealing temperatures. The diameters and heights of as-grown CNTs increased with the catalytic layer thickness from 2 nm to 30 nm. Measurements of the field emission properties of the CNTs showed that the threshold electric fields decreased with larger thickness of the catalytic layers. The anode was ITOcoated glass with the ZnS:Cu,Al green phosphor. Uniform electron emission was observed over a large area of 150 × 150 ㎟ with high emission current and high brightness. Field emitter arrays with multi-walled CNTs grown inside their gated holes were fabricated on glass substrates. The Invar catalyst dots on which the CNTs would be grown were deposited into the gated holes by a self-aligned method to maintain a constant distance between CNT emitters and gate electrodes. The CNTs were synthesized by thermal CVD using a gas mixture of CO and H_(2) at 600 . The height of CNT emitters was controlled by the ratio of flow rates of CO to H_(2). Field emission currents and images were monitored as a function of gate and anode voltages. The CNT emitters grown just up to the gate electrode height operated best in a triode mode. The 5.2” diagonal triode-type CNT emitters fabricated on an a-Si resistive layer with the diffusion barrier by Cr thin film, exhibited the uniform emission images and excellent I-V characteristics. This study also developed a growth - etch back - growth process to obtain aligned CNTs with the expanded dome-type structure on glass substrates using thermal CVD and alternating current plasma enhanced CVD (ac-PECVD). An array of hollow a-Si domes was simply fabricated with symmetrically self-aligned holes at top. As the a-C was grown to penetrate underneath the a-Si layer, the a-Si layer swelled up. The dome height was controllable, depending upon the catalytic metal thickness. Etching the a-C formed the hollow a-Si domes. Even though the a-C remained inside the domes, the CNTs were successfully synthesized with the catalytic reaction of the Invar alloy by ac-PECVD. It is considered that this dome structure can be easily applied to gated FEAs with CNT emitters or MEMS devices.

운동부하시 심박동수 변화에 따른 QT 간격 확산의 특성

박영준 한양대학교 대학원 2000 국내석사

船主責任相互保險에 관한 硏究 : 史的 考察과 法的 問題點을 中心으로

박영준 高麗大學校 大學院 2002 국내박사

Although air transport is faster, carriage of goods by sea is still the major means of transport in international trade. However, there are many potential risks so shipowners and shippers want to cover their risks through marine insurances. Protection and Indemnity (P&I) insurance covers a shipowner's third party liabilities which arise in connection with the operation of the ships. This insurance is one of the major marine insurances along with Hull & Machinery insurance and Cargo insurance. But P&I insurance has different characteristics from the others. Particularly, while both Hull & Machinery insurance and Cargo insurance are normally commercial insurances, P&I insurance is a mutual insurance. Therefore, a P&I club, generally an insurer of P&I insurance, is organized by shipowners and operates on a non-profit basis. In Korea, there was no national P&I club until 2000. Therefore, most of the Korean shipowners' liability risks had been insured by foreign P&I clubs, especially British P&I clubs. At that time, many Korean legal scholars had argued for the necessity of the establishment of a Korean P&I club and one was finally established in January 2000. Their studies, however, had not sufficiently focused on the legal problems of P&I insurance, so more study about these legal problems is required at this time. The purpose of this study is to introduce P&I insurance and to provide possible solutions to its legal problems. It is composed of six chapters. In the first chapter, I deal with the purpose and scope of the dissertation. In the second chapter, I introduce the historical background of P&I insurance and discuss the major legal problems which have historically occurred. Since P&I insurance was created and developed in the English legal system, it is difficult to understand for many people who study law in a Civil Law system, and therefore are not familiar with a Common Law system. Accordingly, studying the historical background of P&I insurance will make it easier to understand the legal problems of such insurance in Korea. In the third chapter, I defines P&I insurance in a Civil Law system. In addition, I deal with the distinctive nature of the P&I insurance contract. In England, it is the majority opinion that P&I insurance is an indemnity insurance, not a liability insurance. In the Korean legal system, however, it is practically impossible to distinguish indemnity insurance from liability insurance because Korean laws generally admit to third party claims against liability insurers. Thus, in a Civil Law system like Korea, P&I insurance should be regarded as a liability insurance, not as an indemnity insurance. In the fourth chapter, I classify the risks covered by P&I insurance and analyze each risk. P&I insurance covers mixed risks which developed in an unplanned, empirical and piecemeal way, so it has been described as a "somewhat miscellaneous group of left overs." In this chapter, I research many rules of P&I clubs and try to classify the risks covered by P&I insurance. An analysis on each risk in connection with the Korean law and International conventions is also provided. In the fifth chapter, I deal with the right of third party direct claims against a P&I club. P&I insurance often has a "pay to be paid" rule in its contract rules. According to this rule, a shipowner must pay his liabilities to victims in advance and then be indemnified for his losses by P&I insurance. As a result, if a third party directly makes a claim against a P&I club, the P&I club would make a plea based on this "pay to be paid" rule. By sticking to the "pay to be paid" rule, however, if someone is injured by an insolvent shipowner, the victim would receive nothing from P&I insurance. It can cause a harsh problem in Korea because Article 724 (2) of the Korean Commercial Law generally admits third party claims against liability insurers. Hence, in order to solve this problem, the "pay to be paid" rule should be only applied to the relationship between a P&I club and a shipowner, not between a P&I club and a third party because Article 724 (2) of the Korean Commercial Law is a compulsory law. By this interpretation, a third party could directly make claims against a P&I club under the Korean law even though there is a "pay to be paid" rule in the rules of the P&I club. In the sixth chapter, I summarize the results of the above studies as a conclusion of this dissertation.

대마섬유와 대마/PP 복합재료의 기계적 특성에 미치는 표면화학처리의 영향

박영준 전북대학교 대학원 2010 국내석사

Recently, synthetic fiber reinforced polymer composite materials are widely used in many industrial areas, which required light-weight and high strength. However, synthetic fibers have high strength but the treatment and disposal of these material as solid wastes after service have become a serious problem. Compared with synthetic fibers, the use of natural fibers in composites are advantageous in certain aspects such as low cost, low density, abundance, biodegradable, non-toxic, etc. Beside these advantages, some of the problems associated with these composites include poor interfacial adhesion between the natural fibers and the polymer matrix. All plant derived cellulose fibers are polar and hydrophilic in nature, mainly as a consequence of their chemical structure. In contrast, Poly-olefins such as polypropylene are largely non-polar and hydrophobic. The incompatibility of the polar cellulose fibers and non-polar thermoplastic matrix leads to poor adhesion, hence the composites that are produced will exhibit poor mechanical properties. Therefore, various chemical treatments have been used to enhance the compatibility between natural fibers and polymer matrix. The efficiency of the interfacial adhesion between matrix and fiber depends on the modification methods. In this study, effect of chemical surface treatment on the mechanical properties of hemp fiber and its composites was discussed. The effect of two different chemical treatments with varying concentration on hemp fiber was evaluated by means of tensile strength, elastic modulus and density. Surface morphologies of the fiber were observed using scanning electron microscopy and FT-IR for characterizing chemically modified fiber. The composite specimens were prepared using untreated, NaOH and silane treated hemp fibers as reinforcement with polypropylene(PP) as matrix. The volume fraction of the fibers in the PP composites was fixed at 30%. Tensile and flexural tests of the composites were performed according to ASTM D3039 and D790-03, respectively. Among the tested samples, 4wt% NaOH treated fiber composites showed the highest values of mechanical properties(σt=29.7MPa, σf=61.9MPa). The fracture surface of the composites was also observed using the SEM to understand the interfacial interaction between fibers and matrix. The water absorption rates of composites were measured and it showed that the process for all specimens sharply increased and approach 95% saturation after 150h. The composites with untreated fiber showed highest water absorbtion and the composites with 6wt% silane treated fiber showed the lowest water absorption.

웨이트·플라이오메트릭 트레이닝 초등학교 어린이의 체력에 미치는 영향

박영준 춘천교육대학교 교육대학원 2003 국내석사

본 연구의 목적은 웨이트 트레이닝과 플라이오메트릭 트레이닝이 초등학교 어린이들의 체력에 미치는 영향을 알아보는 데 있다. 피험자는 강원도 철원군 갈말읍 소재 T 초등학교 5, 6학년 어린이 24명을 무선 표집하여 웨이트 트레이닝을 실시하는 집단, 플라이오메트릭 트레이닝을 실시하는 집단, 특별한 훈련을 하지 않는 집단의 세 집단 각 8명으로 편성하여 주당 3일씩 8주간 훈련을 실시하였다. 웨이트 트레이닝 집단은 김충현이 구성한 프로그램을 적용하였다. 모두 4단계로 나누어 단계별로 9종목의 트레이닝을 실시하였으며, 종목간 60초의 스트레칭을 하며 휴식을 취한 후 이동하고, 전체 운동 시간은 20~30분으로 하였다. 부하량은 1RM의 60~70% 정도로 하고 반복 횟수는 8~15회로 개인의 능력에 맞게 실시하였다. 플라이오메트릭 트레이닝 집단은 4종목으로 구안하여 적용하였으며 3단계로 나누어 실시하였다. 운동 사이의 휴식은 2분으로 하고 전체 운동 시간은 20~30분으로 하였으며 부하량은 단계별로 1세트씩 늘려 나갔다. 이 연구의 측정변인은 근지구력과 순발력, 민첩성, 유연성이었으며 자료의 분석은 트레이닝 전·후의 기록을 측정하여 t-test를 실시하였고 그 결과는 다음과 같았다. 1. 웨이트 트레이닝 집단에서는 근지구력의 기록이 훈련전보다 훈련 후에 현격히 향상되어 통계적으로 유의한 차가 나타났다. 2. 플라이오메트릭 트레이닝 집단에서는 근지구력과 순발력, 민첩성이 트레이닝 후에 현격히 향상되어 통계적으로 유의한 차가 나타났다. 3. 통제 집단에서는 체력 전반에 걸쳐 기록이 향상되었으나 통계적으로 유의한 차는 나타나지 않았다. 4. 플라이오메트릭 트레이닝이 웨이트 트레이닝보다 민첩성을 기르는데 효과적이다. 이상의 연구 결과에 따르면, 웨이트 트레이닝과 플라이오메트릭 트레이닝이 초등학교 어린이들의 체력 향상에 큰 효과가 있다는 것을 알 수 있다. 따라서 초등학교 어린이들의 체력을 향상시키기 위하여 초등학교 수업 현장에 적용할 수 있는 프로그램을 개발하여 체육 시간에 실시하도록 해야할 것이다. This study aims to determine how mush the weight and plyometric training may have effects on the physical strength of elementary schoolers. In this study, total 24 subjects were randomly sampled from elementary schoolers at grade 5 and 6 in 'T' Elementary School, which is located in Galmal-eub, Cheorwon-gun, Gangwon province. The subjects were subdivided into three groups with respective 8 persons: The 1st Group under weight training, the 2nd group under plyometric training and the 3rd group without special training. All groups were asked to participate in 8-week training on the basis of 3 days a week. In this study, a training program devised by Kim Chung-hyeon was applied to weight training groups as sampled. They went through 9 training events in each step from Step 1 to 4. Between events, they were allowed to take a short rest with stretching for one minute to move to the next course. Total physical training time ranged from 20 to 30 minutes. Physical load was set up at 60 to 75% of 1RM(Repetition Maximum). Repetition cycles ranged from 8 to 15 depending upon the physical capacity of each subject. The 2nd group under plyometric training was to participate in 4 devised events from Step 1 to 3. Between events, they were allowed to take a short rest for 2 minutes. Total physical training time ranged from 20 to 30 minutes. Physical load was a little stronger applied to the 2nd group with one set added in course of step. In this study, the variable factors upon the measurement included muscular endurance, instantaneous reactionary ability, agility and flexibility. Data collected from subjects was applied to t-test, based on the records measured before and after training. The results of data analysis can be summarized as follows: 1. The 1st group under weight training showed remarkably better records of muscular endurance after training than before, which involved relatively significant differences in statistical level. 2. The 2nd group under plyometric training also showed much better records of muscular endurance, instantaneous reactionary ability and agility after training, which involved significant differences in statistical level. 3. The 3rd group, i.e. control group showed a little better record throughout all items of physical strength, but did not involve any significant difference in statistical level. 4. It is notable that plyometric training was more effective for raising agility than weight training. Summing up, it is found that weight and plyometric training have more or less considerable effects on enhancing the physical strength of elementary schoolers. Thus, for the better physical strength of our elementary schoolers, it is favorable to develop and a series of training programs available for physical education class in elementary schools.

SPE 정제를 적용한 QuEChERS 잔류농약 분석법의 효율성 비교

朴映準 강원대학교 일반대학원 2015 국내석사

SPE 정제를 적용한 QuEChERS 잔류농약 분석법의 효율성 비교 朴 映 準 江原大學校 大學院 農化學科 다종 농약 동시분석 방법으로 국내에서는 식품공전 잔류농약 분석법 실무 해설서의 다성분 동시 분석법 제 1, 2법이 보편적으로 이용되고 있으며 QuEChERS 분석법의 이용 역시 증가하고 있다. 그러나 전처리 소요 시간의 단축과 정제 효율을 높이기 위해 QuEChERS 분석법을 개선한 STQ(Solid phase Technique with QuEChERS) 분석법이 새로이 도입되었다. 본 연구는 STQ 분석법의 정확성(accuracy)과 재현성(reproducibility) 및 정제효과(efficiency)를 검증하고자 식품공전 다성분 동시 분석법 제 1법, QuEChERS 분석법의 회수율 시험 및 matrix effect의 검증을 실시하여 간섭물질의 제거 효율을 판별할 수 있다. 시험에 사용한 시료 및 장비는 국내 생산 대표 작물인 감자, 사과, 고추, 현미, 대두 5가지 작물로 기체 크로마토그래프(Gas chromatograph)를 이용하였으며, 45종의 농약 성분을 분석 대상으로 선정하였다. 3가지 분석 방법에 대한 다종 혼합 농약의 정밀성을 판단하기 위해 표준검량곡선을 작성한 결과 R² 값은 0.990 이상으로 높은 직선성을 보였고 분석 장비의 최소검출량은 0.1 ng 수준이었다. 2수준으로 3회 반복 실시한 회수율 시험의 상대표준편차(Relative standard deviation, RSD)는 30% 이내로 요구 조건을 충족하였으며 다성분 동시 분석법 제 1법 89.13%, QuEChERS 분석법 92.45%, STQ 분석법 85.27%의 평균 회수율을 보였다. 또한 5가지 시료에 대한 45종 농약성분의 평균 matrix effect는 다성분 동시 분석법 24.61%, QuEChERS 분석법 23.98%, STQ분석법 11.24%로 나타났다. 이 중 STQ 분석법은 QuEChERS 분석법으로 추출한 시료 용액을 고상의 C18, PLS, PSA cartridge column을 차례로 통과하여 용출·정제하는 방법으로 전처리 소요 시간이 짧고 용이하며 높은 정제효과를 보였다. 그러나 전처리 과정에서 농축과정의 생략으로 소량의 추출용매를 분취하여 분석하기 때문에 분석방법의 검출한계(method detection limit, MDL)가 높아지는 문제가 발생하는데, 이를 보완하기 위해 시료의 대량 주입으로 검출한계를 낮추고자 하였다. 대용량 주입장치(large volume injector, LVI)를 이용하여 STQ 분석법을 적용한 분석 결과 표준검량곡선은 0.990이상의 R² 값으로 높은 직선성을 보였고, 검출한계는 0.01 mg/kg 수준이었다. 회수율 시험 결과 91.86%의 평균 회수율을 보였으며 2수준 3회 반복 처리에 따른 상대표준편차는 30% 미만이었고 평균 matrix effect는 17.90%으로 높은 재현성과 정확성, 정제 효과를 나타내었다. □ 핵심주제어(keywords) 잔류농약, 다성분, 대량 주입, Multi-residue pesticide, QuEChERS, Solid phase technique with QuEChERS, STQ, LVI, PTV, Matrix effect Comparative the efficiency of SPE clean-up process applied QuEChERS method Park Young-Jun Department of Agricultural Chemistry Graduate school, Kangwon National University Abstract Recently, multi-residue pesticide batch analysis have been using universally for multi-residue analysis adapting in Korean food code and QuEChERS method. However, STQ(Solid phase Technique with QuEChERS) method was developed to improving clean-up effect and shorten the working hours. This study was conducted to compare with the multi-residue method in Korean food code and QuEChERS method for validated accuracy, reproducibility and efficiency. Total 45 selected and targeted pesticide were analyzed by GC and 5 of them were crops(apple, potato, green pepper, rice, soy bean). R2 values were calculated in the standard calibration curves of three analysis methods where each method sample was over 0.990. Recovery tests were performed by three times repeated in two levels and the relative standard deviation of the repeated experiments was less than 30 %. Average of recoveries in the multi-residue method in Korean food code was 89.13 %, QuEChERS method was 92.45 % and STQ method was 85.27 %. In addition, matrix effects in multi-residue method in Korean food code was 24.61 %, QuEChERS method was 23.98 % and STQ method showed 11.24 %. STQ method is easy and highly clean-up effect in extracted the sample solution by QuEChERS method and clean-up with C18, PLS, PSA cartridge columns. Specially when, a problem occurs because the high detection limit analysis, obtain a small amount of extraction solvent with the omission of the process of concentration from the sample preparing, and to lower the limit of quantitation, therefore large volume of the sample is injected in order to compensate for this. Results of applying the STQ method using a large volume injector, a standard calibration curve showed a higher linearity than the R² value of 0.990, and method detection limit (Method detection limit, MDL) was 0.01 mg/kg. It showed an average recovery of 91.86 % and the relative standard deviations of the three times repeated in two levels process less than 30 % and an average matrix effect was 17.90%. □ Keywords Multi-residue pesticide, QuEChERS, Solid phase technique with QuEChERS, STQ, LVI, PTV, Matrix effect

탄성초음파를 이용한 적외선 치료와 초음파 치료 전.후 근육의 탄력 분석

박영준 순천향대학교 대학원 2018 국내박사

본 연구에서는 적외선치료와 초음파치료에 따른 탄성초음파를 이용한 상지(upper extremity)의 아래팔앞칸(anterior compartment of forearm)에서 위팔노근(brachioradialis muscle)부위와 하지의 뒤칸(posterior compartment of leg)의 장딴지근 가쪽갈래(lateral gastrocnemius muscle) 1cm부위의 치료 전,후 탄성비율의 비교 분석과 키, 몸무게, BMI, 체지방량, 근육량, 기초대사량 등 다양한 변수와의 상관관계를 알아보고자 하였다. 2017년 7월 30일부터 2017년 8월 10일 까지 20대 남자 10명을 대상으로 했다. 초음파 치료 및 적외선 치료 시 근육의 탄성도 증가율은 상지의 forearm 근육 부위에서 초음파로 치료 시 탄성도는 1.55±0.41배 증가하였으며 적외선 치료 시는 1.23±0.10배 증가하였다. 결과적으로 초음파로 치료 시 탄성도가 더 증가하였다. (p<0.05) 이는 1cm 부위에서는 심부치료에 초음파치료가 적외선 치료보다 효과적이며 좋은 결과가 나타날 거라 기대된다. 그리고 초음파치료와 적외선치료가 상지 근육에는 탄력성과 유의한 차이가 있고 하지근육에서는 유의한 차이가 없는 것으로 확인 되었다. 또한 초음파 치료 시와 적외선 치료 시 상지(upper extremity)의 아래팔앞칸(anterior compartment of forearm)에서 위팔노근(brachioradialis muscle) 부위의 탄력도 증가율과 체지방량, BMI가 증가 할수록 탄성도 증가율이 높아지는 것을 알 수 있었다. (p<0.05) 향후 초음파 치료와 적외선 치료 시에 기초자료로 활용 될 수 있다고 사료된다.

ECBGS

박영준 충북대학교 대학원 2013 국내석사

Cancer is a class of complex genetic diseases characterized by out-of-control cell growth. Cancer classification has been a crucial topic of research in cancer treatment. For the last decade, mRNA expression profiling with microarray has been widely used to classify the different types of human cancers. However, microarray data poses a severe challenge for computational techniques. We need dimension reduction techniques that identify a small set of genes to achieve better learning performance. From the perspective of machine learning, the selection of genes can be considered to be a feature selection problem that aims to find a small subset of features that has the most discriminative information for the target. In this thesis, we proposed an Ensemble Correlation-Based Gene Selection (ECBGS) algorithm based on symmetrical uncertainty (SU) and Support Vector Machine (SVM). In our method, symmetrical uncertainty was used to analyze the relevance of the genes, the different starting points of the relevant subset were used to generate the gene subsets, and the SVM was used as an evaluation criterion of the wrapper. During the experiments, we used six freely accessible benchmark datasets from the Internet to meet our objective, which was to evaluate and investigate the performance of our method using the classifiers trained from both 10-cross validation and different sizes of dataset. The results show that the classification model with our proposed gene selection algorithm has higher prediction accuracy and that our method can still achieve high accuracy when the number of training instances is small. Compared with other methods published in the literature, our method yields good results. ECBGS can potentially be used in miRNA expression profiling for cancer classification. Moreover, we believe that our mechanism is also applicable to other feature selection problems and can be expanded to other classifications of disease states. 암 분류는 암 치료에 있어서 가장 기본적이고 중요한 연구 분야이다. 최근 10년간, 마이크로어레이를 이용한 mRNA 발현 프로파일이 다양한 종류의 암을 분류하는데 사용되었다. 마이크로어레이 데이터는 보통 수천 개 또는 수만 개 이상의 유전자로 구성되지만 대상 암과 관련된 유전자는 많지 않다. 따라서 정보량이 많은(informative) 유전자를 선택하는 것은 마이크로어레이 데이터 분석을 위한 필수적인 단계이다. 기계학습 관점에서, 정보량이 많은 유전자를 선택하는 것은 분류에서 관련이 있는 속성(feature)들의 부분집합을 선택하는 속성선택(feature selection)의 문제로 간주할 수 있다. 본 논문에서는, symmetrical uncertainty와 지지도 벡터 기계를 이용한 상관성 기반 유전자 선택 알고리즘을 제안하였다. 제안한 알고리즘에서는 symmetrical uncertainty가 유전자의 관련성(relevance)을 측정하는데 사용되었고, 관련 집합의 서로 다른 유전자를 시작점으로 하여 유전자 부분 집합을 생성하고, 지지도 벡터 기계를 부분 집합 평가 알고리즘으로 사용하였다. 제안한 알고리즘의 효율성을 검증하기 위하여 본 논문에서는 6개의 공개된 유전자 발현 데이터를 사용하였고, 10-fold 교차 검증법과 다양한 크기의 데이터 집합을 사용하였다. 그 결과, 제안한 유전자 선택 기법을 통해 구축된 분류 모델은 다른 알고리즘에 비해 높은 정확도를 보였고, 또한 데이터의 크기가 작을 경우에도 높은 성능을 보였다. 제안하는 ECBGS는 miRNA 발현 데이터를 이용한 암 분류에도 사용 될 수 있다. 뿐만 아니라, 제안하는 알고리즘은 다른 종류의 속성 선택 문제에도 적용을 할 수 있고, 여러 가지 질병 상태를 분류하는 문제를 해결하는 방법으로도 확장할 수 있다.

“생명윤리 및 안전에 관한 법률(생명윤리법)”의 지식 및 인식도 조사

박영준 고려대학교 대학원 2007 국내석사

A Survey for the degree of Knowledge and Recognition of Informed Consent Document on the Specimen Donation Based on the Current Bioethics and Biosafety Law. Background: It is absolutely necessary to obtain an adequate informed consent from the patients when samples were collected for genetic diagnosis and/or future research since the Bioethics & Biosafety Law (BBL, No. 7150) enforcement in 2005 in Korea. Aim: This study was performed to investigate a practical knowledge and the degree of recognition of the current BBL in different individuals in Korea. Materials and Methods: The questionnaires were prepared three parts including 5 questions for general characteristics and voluntary agreement of the subjects for the present survey, 10 questions for knowledge and 15 questions for the degree of recognition on the BBL, that is attached with the survey questions and surveyed 444 subjects composed of medical school students (n=249), non-medical school students (n=91), non-medical researchers (n=22) and hospital employees (n=82). Results are expressed as means &#61617; SEM, and the differences were determined by one-way analysis of variance (ANOVA), Chi-square analysis and statistical significance was accepted within P < 0.05 as determined by Scheffe' s multiple comparative analysis and logistic regression. Results: A practical knowledge of subjects on the BBL was low in general. On the other hand, the recognition as well as the need of BBL was high in all individuals independent of occupations. Especially, all participants answered negative mind to the ethics of domestic scientists and medical scientists. Conclusion: These results elucidated that specific educational needs are increasing for related professions as well as public populations to improve the effective enforcement of the BBL and develop the biomedical science. Moreover, it may need the practical agreement sheet for the individual fields of biomedical research to actual development. Key words: Bioethics and Biosafety Law, Informed consent, Survey.