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가는잎쐐기풀이 Alloxan 誘發 高血糖 쥐에 미치는 영향
도태자,곽종환,고인자,유승조 성균관대학교 약학연구소 1990 成均藥硏論文集 Vol.2 No.1
Abstratc-Urtica angustifolia has been used to cure diabetes etc. as a folk medicine. The anit-diabetic effect of U. angustifolia was investigated by the experimental diabetic model in rats. U. angustifolia extracts were administered before and after injection of alloxan(50 mg/kg, i.v.), and the blood glucose and serum cholesterol levels were determined at 3 days after alloxan injection. The increased blood glucose and serum total cholesterol levels in the diabetic rats induced by alloxan were significantly decreased by administration of MeOH and BuOH extracts, relatively. And reduced body weight was recovered with the treatments of each extract. The MeOH and BuOH extracts of U. angustifolia showed remarkable anti-diabetic effect, and MeOH extract showed more strong anti-diabetic effect than BuOH extract.