Abstratc-Urtica angustifolia has been used to cure diabetes etc. as a folk medicine. The anit-diabetic effect of U. angustifolia was investigated by the experimental diabetic model in rats. U. angustifolia extracts were administered before and after i...
Abstratc-Urtica angustifolia has been used to cure diabetes etc. as a folk medicine. The anit-diabetic effect of U. angustifolia was investigated by the experimental diabetic model in rats. U. angustifolia extracts were administered before and after injection of alloxan(50 mg/kg, i.v.), and the blood glucose and serum cholesterol levels were determined at 3 days after alloxan injection. The increased blood glucose and serum total cholesterol levels in the diabetic rats induced by alloxan were significantly decreased by administration of MeOH and BuOH extracts, relatively. And reduced body weight was recovered with the treatments of each extract. The MeOH and BuOH extracts of U. angustifolia showed remarkable anti-diabetic effect, and MeOH extract showed more strong anti-diabetic effect than BuOH extract.