http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Islam, Md Rafiqul,Bach, Long Giang,Vo, Thanh-Sang,Lee, Doh C,Lim, Kwon Taek American Scientific Publishers 2014 Journal of Nanoscience and Nanotechnology Vol.14 No.8
<P>A facile synthetic route has been developed for the covalent grafting of biocompatible poly(lactic acid) (PLA) onto CdSe Quantum Dots (QDs) using surface initiated ring opening polymerization (ROP) to afford CdSe-g-PLA nanocomposites. At first, 2-mercaptoethanol (ME) capped CdSe QDs were synthesized through a wet chemical process. The surface initiated ROP of lactide was accomplished with Sn(Oct)2 to give CdSe-g-PLA nanocomposites having surface hydroxyl functionality. FT-IR data suggested that a robust covalent bond was formed between ME capped CdSe QDs and polymer moieties. The grafting density of PLA on CdSe QDs was found to be moderate as measured by TGA analysis. The CdSe QDs were well dispersed in CdSe-g-PLA nanocomposites matrices as captured by TEM. The cubic phase crystal structure of CdSe QDs in the nanocomposites was determined by XRD. The optical properties of the CdSe-g-PLA nanocomposites were investigated by UV-vis and photoluminescence spectroscopy which suggested their potentialities as optical materials in biomedical application. Cell viability studies revealed that the biocompatibility of CdSe QDs was improved upon PLA immobilization.</P>
Islam, M Rafiqul,Bach, Long Giang,Seo, Sung Yong,Lim, Kwon Taek American Scientific Publishers 2013 Journal of Nanoscience and Nanotechnology Vol.13 No.1
<P>Biocompatible magnetic nanocomposites of Fe-AuNPs and poly(2-hydroxylethyl methacrylate) (PHEMA) were employed as a strategic protein immobilization platform. The hybrid magnetic nanocomposites were prepared by applying a 'grafting to' ATRP protocol. Fe-AuNPs having Fe core and Au shell were initially prepared by the inverse micelle method. Disulfide-containing PHEMA (DT-PHEMA) was grafted to the Fe-AuNPs surface by taking the advantages of the thiol chemistry. The grafting of DT-PHEMA to the Fe-AuNPs was confirmed by relevant spectroscopic analyses. The superparamagnetic property, a basic requirement for facile protein immobilization, of the magnetic nanocomposites was measured by the SQUID analysis. Lysozyme, gamma-globulins and bovine serum albumin (BSA) were immobilized onto magnetic nanocomposites via the adsorption strategy. The absorption intensity of lysozyme, gamma-globulins and BSA on the PHEMA grafted Fe-AuNPs were observed to be higher than that of bare Fe-AuNPs.</P>
Islam, Md Rafiqul,Bach, Long Giang,Vo, Thanh-Sang,Lim, Kwon Taek American Scientific Publishers 2015 Journal of Nanoscience and Nanotechnology Vol.15 No.1
<P>A simple protocol for covalent immobilization of biotin onto the surface of Fe3O4 magnetic nanoparticles (MNPs) for improving the biocompatibility of original MNPs has been realized. MNPs were first prepared by co-precipitation method which was subsequently anchored with functionalized biotin. The as-synthesized MNPs were observed to be monocrystalline as evidenced from XRD and TEM images. The covalent grafting of biotin to MNPs was confirmed by FT-IR. The XPS analysis suggested the successful preparation of Biotin-f-MNPs. The as-synthesized Biotin-f-MNPs were found to be superparamagnetic character as recorded by SQUID. Cell viability studies revealed that the biocompatibility of MNPs was improved upon Biotin immobilization.</P>
Rafiqul Islam,Shamima Choudhury,S. N. Rahman,Mohammad Jellur Rahman 한양대학교 세라믹연구소 2012 Journal of Ceramic Processing Research Vol.13 No.3
The structural and electrical properties of pure and manganese doped barium titanate (BaTiO3) with a general formula BaMnxTi1-xO3 (where x=0.00, 0.01, 0.02, 0.03, and 0.04) were investigated. For the observation of the surface morphology and estimation of grain sizes scanning electron microscopy (SEM) was employed. The grain size of BaTiO3 increased with an increase of the Mn doping. The Curie temperature (Tc) which indicates the tetragonal-to-cubic transition, of each sample was found from the resistivity versus temperature curve, and Tc of BaTiO3 increased linearly with an increase of the Mn doping. The Tc of un-doped BaTiO3 was lower than that of the doped samples. The Tc value of pure BaTiO3 was found to be 120 oC. It was found that the dielectric constant versus temperature curve also shows a similar type of Tc. The dielectric constant of BaMnxTi1-xO3 was found to decrease with an increase of Mn doping and the Tc of BaTiO3 increases with the addition of Mn. The structural and electrical properties of pure and manganese doped barium titanate (BaTiO3) with a general formula BaMnxTi1-xO3 (where x=0.00, 0.01, 0.02, 0.03, and 0.04) were investigated. For the observation of the surface morphology and estimation of grain sizes scanning electron microscopy (SEM) was employed. The grain size of BaTiO3 increased with an increase of the Mn doping. The Curie temperature (Tc) which indicates the tetragonal-to-cubic transition, of each sample was found from the resistivity versus temperature curve, and Tc of BaTiO3 increased linearly with an increase of the Mn doping. The Tc of un-doped BaTiO3 was lower than that of the doped samples. The Tc value of pure BaTiO3 was found to be 120 oC. It was found that the dielectric constant versus temperature curve also shows a similar type of Tc. The dielectric constant of BaMnxTi1-xO3 was found to decrease with an increase of Mn doping and the Tc of BaTiO3 increases with the addition of Mn.
Multiple congenital anomalies in a Korean native calf (Bos taurus coreanae)
Islam, Mohammad Rafiqul,Roh, Yoon-Seok,Cho, Ara,Park, Heejin,Heo, Soo Young,Lee, Kichang,Lee, Han Kyung,Lim, Chae Woong,Kim, Bumseok The Korean Society of Veterinary Science 2011 大韓獸醫學會誌 Vol.51 No.1
Supernumerary ectopic limb(s) (SEL) is a congenital anomaly defined as the presence of accessory limb(s) attached to various body regions. This paper describes a case of SEL with ectopic lung and ectopia cordis in a newborn calf, based on macroscopic, microscopic and radiographic findings. External features of multiple congenital anomalies included an ectopic lung growing over the middle of the backbone and covered with normal haired skin. Ectopia cordis was found in the abdominal cavity and attached to the liver. Two extra abnormal limbs originated separately from within the ectopic lung. Most of the abdominal organs were exposed to the outside through the opened abdominal cavity. Microscopically the ectopic lung tissue had edema in the connective tissue around the bronchus and artery. Changes in other organs included congestion of the renal medulla, infiltration of inflammatory cells (lymphocytes and eosinophils) around the hepatic portal tract, and edema surrounding blood vessels and neurons in the brain. The rudimentary humerus of the forelimb was attached to the thoracic spine, as viewed radiographically. The hindlimb was consisted of an irregularly shaped femur, short tibia and fibula, two tarsal bones, one metatarsal bone, and three phalanges. This is the first description of congenital anomalies involving the SEL, ectopic lung and ectopia cordis in a calf.
Evaluation of immunomodulatory effects of zearalenone in mice
Islam, Mohammad Rafiqul,Kim, Jong Won,Roh, Yoon-Seok,Kim, Jong-Hoon,Han, Kang Min,Kwon, Hyung-Joo,Lim, Chae Woong,Kim, Bumseok Informa UK (TaylorFrancis) 2017 Journal of immunotoxicology Vol.14 No.1
<P>Zearalenone (ZEA) is a non-steroidal estrogenic mycotoxin produced by Fusarium species. The toxicity of ZEA has been evaluated for reproductive and developmental effects; however, there is little evidence about its acute toxicity or general immunotoxicity. In the present study, immune regulatory functions were investigated in mice that had been exposed to ZEA (5 or 20 mg/kg BW) daily for 14 days. Results showed that sub-populations of CD4(+), CD8(+) and CD11c(+) cells in the spleen and CD4(+), CD8(+) and F4/80(+) cells in the mesenteric lymph nodes (MLN) of ZEA (20mg/kg)-exposed hosts were decreased compared to those in the control mice. However, CD19(+) and CD11c(+) cells were increased in the MLN of the ZEA mice and CD4(+)CD25(+)Foxp3(+) cells were decreased in the spleen and MLN. There were differential changes in the immune cell populations of the small intestine of the ZEA mice as well, depending on small intestine location. In ex vivo experiments, ZEA treatments resulted in increased proliferative capacities of mitogen-induced splenocytes and MLN cells; such changes were paralleled by significant increases in interferon (IFN)-gamma production. With regard to serum isotypes, IgM levels were decreased and IgE levels were increased in the 20 mg/kg ZEA-treated mice. Mucosal IgA levels were decreased in the duodenum and vagina of these hosts. Serum analyzes also revealed that tumor necrosis factor (TNF)-alpha levels were decreased and interleukin (IL)-6 levels increased as a result of ZEA exposures. ZEA treatment also led to increased apoptosis in the spleen and Peyer's patches; these changes were associated with changes in the ratios of Bax:Bcl-2. Following priming with different TLR ligands, ZEA exposure led to differentially modulated TLR signaling and variable production of pro-and anti-inflammatory cytokines in RAW 264.7 macrophage cells. Taken together, these results indicated that ZEA could alter the normal expression/function of different immune system components and this would likely lead to immunomodulation in situ.</P>
Islam, Md Rafiqul,Bach, Long Giang,Jeong, Jung Hyun,Kim, Hyun Gyu,Lim, Kwon Taek American Scientific Publishers 2013 Journal of Nanoscience and Nanotechnology Vol.13 No.5
<P>A nanocomposite of TiO2 nanoparticle with an electroactive poly(4-vinylpyridine) (PVP) was synthesized via a simple surface thiol-lactam initiated radical polymerization upon grafting from protocol. This can be achieved through the primary modification of the TiO2 surface with a silane coupling agent leading to thiol functionalized TiO2 (TiO2-SH). Subsequently, a controlled radical polymerization of 4-vinylpyridine in the presence of TiO2-SH and butyrolactam afforded PVP-g-TiO2 nanocomposites. The grafting of PVP on the surface of TiO2 was confirmed by FT-IR, TGA, XPS, EDX, TEM and SEM analyses. The UV-vis studies of the synthesized PVP-g-TiO2 nanocomposite demonstrated an exceptionally good dispersibility in organic solvents.</P>
Md. Rafiqul Islam,Jeong-Eui Hong,Hoy-Taek Kim,Jong-In Park,Ill-Sup Nou 한국원예학회 2021 한국원예학회 학술발표요지 Vol.2021 No.10
Acidovorax citrulli (A. citrulli) strain causes bacterial fruit blotch (BFB) in cucurbit crops and watermelon, is an economically devastating disease in watermelon. Molecular characterization of causal strains and identification of sources of resistance are essential to control this important disease. BFB were identified by partial sequencing and documented in GenBank. Recently, there was an outbreak of BFB strain NIHHS16-088 in watermelon fields (North Jeolla Province, South Korea) that severely hampered watermelon production in Korea. Therefore, we characterized NIHHS16-088 by partially sequencing the 16S rRNA gene using PCR-based markers. The partial sequence of the 16S rRNA gene of NIHHS16-088 was much more similar to A. citrulli strains allied with watermelon and melon hosts than other cucurbit hosts. A PCR-based assay identified the strain (NIHHS16-088) as belonging to A. citrulli group II, which mostly infects watermelon cucurbits (virulent to watermelon). Seventy watermelon accessions were screened against NIHHS16-088 in a detached-leaf inoculation assay. The lack of visible disease symptoms 12 days after inoculation in lines SNKW41 and SNKW85 indicated these to be highly resistant, whereas moderate resistance was observed in SNKW60, SNKW61, SNKW103 and SNKW104. The characterized A. citrulli strain NIHHS16-088 (group II) and identified resistant lines will assist as a precious resource for further genetic studies and development of BFB resistance in watermelon.