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심현보 ( Hyun Bo Sim ),김민지 ( Min Ji Kim ),채수열 ( Soo Yuhl Chae ),이원주 ( Weon Ju Lee ),이석종 ( Seok-jong Lee ),김도원 ( Do Won Kim ),장용현 ( Yong Hyun Jang ) 대한피부과학회 2017 대한피부과학회지 Vol.55 No.5
Some morphological variants of benign fibrous histiocytoma (dermatofibroma) present with distinct clinical features. In particular, atypical, aneurysmal, and cellular fibrous histiocytoma are associated with a significant risk of local recurrence. Furthermore, very rarely, cutaneous fibrous histiocytoma can lead to metastatic disease. Deep benign fibrous histiocytoma is an uncommon and poorly recognized clinical subtype that arises in subcutaneous or deep soft tissue. Deep benign fibrous histiocytoma has many histologic features in common with cellular fibrous histiocytoma. Deep benign fibrous histiocytoma recurs in approximately 20% of cases and may rarely metastasize. We report a rare case of deep benign fibrous histiocytoma with metastatic potential in a 38-year-old man who presented with a 2-year history of a recurrent hard mass on his left shoulder. (Korean J Dermatol 2017;55(5):301∼304)
A clinicohistopathological analysis of cutaneous fibrous histiocytomas of the finger
( Sang-woo Park ),( Jin Park ),( Seok-kweon Yun ),( Han-uk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Cutaneous fibrous histiocytoma is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, cutaneous fibrous histiocytoma on the finger is uncommon. Objectives: This study was undertaken to examine the clinicohistopathologic features of cutaneous fibrous histiocytoma of the finger. Methods: This is a retrospective study of 12 cutaneous fibrous histiocytomas located on fingers in a tertiary hospital in Korea. All case slides were retrieved from saved files for diagnostic verification. Results: Cutaneous fibrous histiocytomas of the finger affected 9 to 48 year-olds in a 1.4:1 male to female ratio. Picker’s nodule or wart was the most common clinical diagnosis. In only 2 out of the 12 cases was the pre-biopsy diagnosis of cutaneous fibrous histiocytoma ventured. Fibrocollagenous type was the most common histologic type. Majority of cases were mitotically inactive, exhibiting only 0-1 mitoses per 10 high power field and there was no recurrence. Tumor cells were uniformly CD34 negative. Conclusion: Because cutaneous fibrous histiocytoma can resemble malignancies including dermatofibrosarcoma protuberans, a lack of familiarity with the occurrence of cutaneous fibrous histiocytoma of the finger may lead to more aggressive treatment. Dermatologists should include cutaneous fibrous histiocytoma in their differential diagnosis of circumscribed nodules on the fingers to ensure proper management.
Short Report : 동맥류성 양성 섬유성 조직구종 1예
선정우(Jung Woo Sun),김정수(Jung Su Kim),김영조(Young Jo Kim),정병수(Byoung Soo Chung) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.2
Aneurysmal benign fibrous histiocytoma, which is a rare variant of benign fibrous histiocytoma, usually occurs as a solitary nodule on the limbs of young to middle aged adults. The clinical diagnosis of fibrous histiocytoma is seldom considered in the differential disgnosis, which may include malignant melanoma, hemangioma, neurorfibroma, and nonspecific cyst. Histopathologically, aneurysmal benign fibrous histiocytoma is characterized by the presence of large blood-filled tissue space which is surrounded by histiocyte, fibroblast, hemosiderin pigment, and capillaries. We report a case of aneurysmal benign fibrous histiocytoma in a 15-year-old boy, who had a solitary nodular lesion on the left knee for a 2 year duration. (Korean J Dermatol 2000;38(2):298~301)
민창수(CS Min),정을영(EY Jeong),진건(K Jin) 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.11
Benign fibrous histiocytoma is a tumor composed of a mixture of fibroblastic and histiocytic cells that are often arranged in a cartwheel or storiform pattern and accompanied by varying number of inflammatory cells, foam cells, and siderophages. Benign fibrous histiocytoma represents one of the common soft tissue tumors with most cases presenting in the skin. The common sites of incidence are the limbs, trunk, head, neck, and posterior peritoneal cavity:less commonly, these lesions arise in female reproductive organs. This report documents a case of benign fibrous histiocytoma arising in the ovary of 48 year-old female whose chief complaint was abdominal pain.
상악 치은에 발생한 양성 섬유성 조직구종에 대한 증례 보고
박상준,정지아,서고은,송준호 대한구강악안면병리학회 2010 대한구강악안면병리학회지 Vol.34 No.3
Benign fibrous histiocytomas that is also known asDermatofibroma,Fibrous dermatofibroma, andFibrous histiocytoma are benign skin growths. They are composed of disordered collagen laid down by fibroblasts. In rare cases, basal cell carcinoma may develop in that. Benign fibrous histiocytomas of bone are unusual neoplasms that often are confused with metaphyseal fibrous defects. It is an uncommon neoplasm of the Head and Neck region. It is a rare and usually painless oral tumor. Several cases were reported in mandible, but few in maxilla, especially in maxillary gingiva. We are reporting a case of Maxillay gingival.
조인지,허성재,전범수,김정수 대한비과학회 2010 Journal of rhinology Vol.17 No.2
Fibrous histiocytoma usually develops indiscriminately in skin and any soft tissues of the body. To date, tumors occurring in soft tissues of the head and neck, especially around the nose, have been rarely reported. In most cases, benign fibrous histiocytoma develops as a painless mass lesion and most commonly originates in sun-exposed skin, extremities, and orbital tissue. Recently, we experienced a case of benign fibrous histiocytoma in the nasal dorsum in a 36-year-old woman who complained of a mass in the nasal dorsum. To the best of our knowledge, this is the first reported case of benign fibrous histiocytoma originating in the nasal dorsum in a Korean.
슬관절내에 발생한 양성 섬유성 조직구종 - 1례 보고 -
하권익,한성호,정민영,양보규,유재훈 ( Kwon Ick Ha,Sung Ho Hahn,Min Young Chung,Bo Kyu Yang,Jae Hoon Ryu ) 대한슬관절학회 1993 Knee Surgery and Related Research Vol.5 No.2
Benign fibrous histiocytoma is characterized by proliferation of histiocytes and fibroblast-like cells. It is practically always distributed between the tendon seath and synovium of the wrist and fingertips and between the ankle and toetips but uncommon in the knee. We experienced a case of benign fibrous histiocytoma in a 38 year-old male patient who complained of pain and a palpable mass on the medial aspect of the left knee, which was treated surgically, Arthroscopy aod excisional biopsy showed protruded mass in the joint space. So, we report it with review of literature.
( Ji Min Chung ),( Sun Nam Koong ),( Ji Hyun Sim ),( Joong Sun Lee ),( Seung Phil Hong ),( Myung Hwa Kim ),( Byung Cheol Park ) 대한피부과학회 2011 Annals of Dermatology Vol.23 No.2s
Compared to cutaneous benign fibrous histiocytoma (BFH), deep-seated BFH is very rare and poorly recognized. Both cutaneous and deep-seated BFH are usually asymptomatic. We herein report a 25 year-old woman who presented with a painful mass in her foot that was poorly controlled by analgesics and associated with walking difficulty. After preoperative ultrasonographic evaluation, the mass was completely excised and histologic exam showed spindle cells loosely arranged in storiform architecture, with CD34-, desmin-, S-100-, focal CD68+, vimentin+, smooth muscle actin+, and factor XIIIa+. The patient was diagnosed with deep-seated BFH based on the histologic, radiologic and intraoperative findings. (Ann Dermatol 23(S2) S239~S242, 2011)