http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Yeun‑Ah Joo,Young‑Kyun Kim,윤태식,Kee‑Ahn Lee 대한금속·재료학회 2018 METALS AND MATERIALS International Vol.24 No.2
This study investigated the microstructure and high temperature oxidation property of Fe–Cr–B metal/ceramic compositemanufactured using powder injection molding process. Observations of initial microstructure showed a unique structurewhere α-Fe and (Cr, Fe)2B form a continuous three-dimensional network. High temperature oxidation tests were performedat 900, 1000 and 1100 °C, for 24 h, and the oxidation weight gain according to each temperature condition was 0.13, 0.84and 6.4 mg/cm2, respectively. The oxidation results according to time at 900 and 1000 °C conditions represented paraboliccurves, and at 1100 °C condition formed a rectilinear curve. Observation and phase analysis results of the oxides identifiedCr2O3and SiO2at 900 and 1000 °C. In addition to Cr2O3and SiO2,CrBO3and FeCr2O4formed due to phase decompositionof boride were identified at 1100 °C. Based on the findings above, this study suggested the high temperature oxidationmechanism of Fe–Cr–B metal/ceramic composite manufactured using powder injection molding, and the possibility of itsapplication as a high temperature component material was also discussed.
증례 : 감염 ; Streptococcus dysgalactiae의 침습적 감염 2예와 emm 유전자형 분석
허주연 ( Joo Yeun Hu ),김은희 ( Eun Hee Kim ),이혜원 ( Hye Won Lee ),차선아 ( Seon Ah Cha ),최준영 ( Joo Young Choi ),김윤정 ( Youn Jeong Kim ),김상일 ( Sang Il Kim ) 대한내과학회 2014 대한내과학회지 Vol.87 No.5
Streptococcus dysgalactiae Subspeciesequisimilis는 인후염, 봉와직염을 일으키지만, 심내막염, 균혈증과 같은 침습적인 감염을 일으키기도 한다. 이의 병원성에는 emm유전자에 의해 발현된 M단백질이 큰 역할을 하며 emm유전자에 대한 중요성이 대두되고 있다. 저자들은 Streptococcus dysgalactiae Subspecies equisimilis에 의한 심내막염와 봉와직염으로 인한 균혈증이 발생하여 효과적으로 치료한 증례 2예와 균주의 emm유전자 염기 서열 분석 결과를 보고한다. 최근 국내에서Streptococcus dysgalactiae에 의한 침습성 감염이 출현하는 것으로 보여, 이에 대한 주의 및 추후 이 균에 대한 유전자형 연구가 이루어져야 할 것으로 생각한다. Recently, invasive infections with the human pathogen Streptococcus dysgalactiae subspeciesequisimilis (SDSE) have increased around the globe. Typing of the emm gene of SDSE, which encodes a virulence factor (M protein), has provided important information. Here, we report two cases of invasive SDSE infection that presented with endocarditis and bacteremia, and their emm gene types. (Korean J Med 2014;87:630-635)
텔레비전 콘텐츠 포맷 산업 및 유통에 관한 포맷 관련 전문가 인식
박주연(Joo-Yeun Park),배진아(Jin Ah Bae) 한국언론학회 2010 한국언론학보 Vol.54 No.3
The format industry is growing very rapidly in the global broadcasting market. Formats have enabled producers and distributors to adapt and reproduce globally. This study attempts to identify the current trends of 1V format business in Korea and to analyze the types and characteristics of the distribution for formats. It aims to understand the current state of format business in Korea, as well as the economic and cultural status of formats in television industry. This study conducted in-depth interviews and a workshop with the experts from the format industry and the academic field. The results of this analysis show that the korean format market has been opened to global formats, but it is still in the early stages due to the lack of clear business models in the broadcasting market. This study attempts to discuss the implications of the format business for the Korean media industry. It is needed that policy makers implement measure to strengthen format's legal status to support Korean formats in the international format industry.
Ha, Seon-Ah,Shin, Seung Min,Kim, Hyun Kee,Kim, Sanghee,Namkoong, Hong,Lee, Youn Soo,Kim, Hae Joo,Jung, Sang Min,Lee, Yu Sun,Chung, Yeun Jun,Park, Yong Gyu,Jung, Sang Seol,Kim, Jin Woo John WileySons, Ltd 2009 JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol. No.
<P>Obese women have an increased risk for post-menopausal breast cancer. The physiological mechanism by which obesity contributes to breast tumourigenesis is not understood. We previously showed that <I>HCCR-1</I> oncogene contributes to breast tumourigenesis as a negative regulator of p53 and detection of HCCR-1 serological level was useful for the diagnosis of breast cancer<SUB>.</SUB> In this study, we found that the HCCR-1 level is elevated in breast cancer tissues and cell lines compared to normal breast tissues. We identified apolipoprotein E (ApoE) interacting with HCCR-1. Our data show that HCCR-1 inhibits anti-proliferative effect of ApoE, which was mediated by diminishing ApoE secretion of breast cancer cells. Finally, HCCR-1 induced the severe obesity in transgenic mice. Those obese mice showed severe hyperlipidaemia. In conclusion, our results suggest that HCCR-1 might play a role in the breast tumourigenesis while the overexpression of HCCR-1 induces the obesity probably by inhibiting the cholesterol-lowering effect of ApoE. Therefore, HCCR-1 seems to provide the molecular link between the obesity and the breast cancer risk.</P>
중등도 이상의 위험 수술을 받은 환자에서 수술 전후 항혈전제 약물 사용 평가
이현아,조윤희,조윤숙,한현주,이주연,정근화,이상건,Lee, Hyeon-Ah,Jo, Yun Hee,Cho, Yoonsook,Hahn, Hyeon Joo,Lee, Ju-Yeun,Jung, Keun-Hwa,Lee, Sang Kun 한국임상약학회 2017 한국임상약학회지 Vol.27 No.1
Objective: The perioperative management of antithrombotic therapy is often challenging and it requires a fine balance between the risk of hemorrhage and thrombosis. We aimed to evaluate the antithrombotic management for moderate to high risk patients in real world setting. Methods: Among the patients who were consulted to the neurologist for the evaluation of perioperative risk from 2010 to 2012, patients undergoing moderate to high risk surgery and taking antithrombotics within 30 days were identified. We analyzed the timing of discontinuation and reinitiation of antithrombotic drugs before or after surgery as well as the status of bridging therapy. In addition, the conformity with the guideline suggested by American College of Chest Physicians was assessed. The rate of thromboembolic event and major hemorrhage were also investigated. Results: A total of 329 patients were included. The concordance rate of warfarin stop and restart time with guideline was 23.4% and 10.3%, respectively. Continuing aspirin in patients undergoing coronary artery bypass surgery or non-cardiac surgery in patients with high risk for cardiovascular events were 59.2% and 2.6%, respectively. Bridging therapy was adopted in 92.9% and 81.2% in patients who had received anticoagulant before surgery and who were at high and low risk thromboembolism, respectively. In entire cohorts, 30-day incidence of major bleeding and thromboembolic event were 31.9% and 3.0%. Co-morbid renal disease were shown as independent predictor for major bleeding (adjusted OR 2.65. 95% CI 1.33-5.28). Conclusion: The concordance rate with guideline regarding perioperative antithrombotic use was low and bridging therapy was prevalent in patients undergoing moderate to high risk surgery.
Kim, Eun-Kyu,Kim, Ji Hyun,Kim, Hyun-Ah,Seol, Hyesil,Seong, Min-Ki,Lee, Joo-Young,Byeon, Jangmoo,Sohn, Yeun Ju,Koh, Jae Soo,Park, In-Chul,Noh, Woo Chul Potamitis Press 2013 Anticancer research Vol.33 No.9
<P>Pre-clinical data support a link between the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway and chemoresponsiveness. We evaluated whether the expression of phosphorylated AKT (p-AKT) or phosphorylated S6 kinase-1 (p-S6K1), a key effector of the mTOR pathway, could be a predictive marker for chemoresponsiveness in breast cancer.</P>
비소세포폐암의 난소전이 환자에서 Erlotinib을 사용한 치료
정익주,임승택,최연석,장태수,오선희,이주아,조도연 이화여자대학교 의과학연구소 2015 EMJ (Ewha medical journal) Vol.38 No.1
Ovarian cancer is generally primary cancer and less frequently originates from metastasis from non-gynecological cancer. Ovarian metastasis from lung cancer represents only 2~4% of all ovarian metastatic cancers. We report a case of ovarian metastasis of non-small cell lung cancer with epidermal growth factor receptor mutation. The patient underwent cytoreductive surgery for the ovarian mass and erlotinib therapy for the metastatic lung cancer. Erlotinib therapy markedly decreased the size of lung mass.