自生 山菜類의 開發에 관한 硏究

申永澈,金在佶,申貞和 충북대학교 농업과학기술연구소 1992 農業科學硏究 Vol.10 No.1

In order to use as vegetable, studies on valuable wild plants-Pimpinella brachycarpa, Cryptotaenia japonica., Synurus deltoids., Solidago virga-aurea var. gigantean., Hemerocallis fulva. Were carried out by field observation and cultivation. The result were obtained as follow : 1. Pimpinella brachycarpa, Cryptotaenia japonica, Solidago virga-aurea var. gigantea were distributed at the higher altitude of 600M, but Synurus deltoids, Hemerocallis fulva were distributed under 500M. 2. Pimpinella brachycarpa, Cryptotaenia japonica, Solidago virga-aurea vat. Gigantean, Hemerocallis fulva except Synurus deltoids grew well on fertile soil in habitat. 3. The germination of Hemerocallis fulva were promoted at 25℃ under dark condition with Ethrel, whereas Synurus deltoides were promoted at 20℃ under dark condition with IBA treatment. 4. Te transplant seedlings of 5 plants, shading was necessary. Low light intensity under 5000Lux is recommended for low rate of bolting and for softening of tissue. 5. All 5 plants grew vigorously toward the end of July. 6. Plants would be harvested after 3 years with seed germination, but it would be desirable to transplant in order to reduce cultivation time. 7. It is desired that 5 plants should be subjected to suppressing or forcing cultivation.

LaCrO_(3) 후막의 가스 감도 특성

신정호,장재영,김정규,박기철 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

LaCrO_(3) thick film sensors were fabricated on an alumina substrate by screen printing method. The sensitivities for gases were investigated by varying the heat treatment temperatures of the films. The sensitivities of LaCrO_(3) thick film for Gallo and NH_(3) gases were better than for CO and NO gases. The best condition of heat treatment was 450℃ and the optimal operating temperature of LaCrO_(3) thick film for the highest sensitivity was 400℃. Sensitivities of LaCrO_(3) thick films about at 3000ppm for C_(4)H_(10) and NH_(3) gases were 85% and 95%, respectively.

노년기에 처음으로 발생한 조증 삽화

신석철,김정란,지익성 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

It has been known that mania in the elderly was a uncommon condition, but the incidence of first admissions for mania tends to increase with advancing age. The etiology of late-onset mania appears to be more heterogeneous, which including identifiable causes, especially brain diseases. The psychopathology of late-onset mania is often attenuated and less severe than in the young. Lithium remains the primary medication in mania in the elderly. However, certain anticonvulsants (valproic acid and carbamazepine) have a number of advantages, including a more tolerable as patients with secondary mania due to neurological and other medical disorders. We report a case of first-episode mania in 73-year old woman, who was treated with valproic acid for 2 weeks to attain stabilizing her symptoms.

이중중합 수복재의 시간경과에 따른 중합도 변화

정태성,김신,양철호 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.3

심미적 수복 재료인 복합 레진과 글래스 아이오노머 시멘트는 중합방식에 따라 화학중합형, 광중합형, 그리고 이 두 가지 중합방식을 겸비한 이중중합형으로 분류할 수 있다. 화학중합형과 광중합형에 대해서는 지금까지 다수의 보고가 있었으나, 충전용 복합 레진의 경우 이들과 이중중합형을 비교한 예는 아직 찾기 힘든 실정이었으므로,이러한 관점에서의 연구가 필요할 것으로 사료되었다. 이 연구에서는 이중중합 수복재가 단일중합방식에 비해 어떠한 특성을 보이는지를 탐구하고자 하였다. 사용된 재료는 광중합형 복합 레진인 Veridonfil-Photo와 이중중합형인 Bis-core,이중중합형인 글래스 아이오노머 시멘트인 Fuji Ⅱ LC와 화합중합형인 Ketac-fil을 사용하였다. 가로 30mm,세로 30mm 높이 1mm와 3mm인 두 종류의 아크릴릭 몰드 중앙에 직경 7mm의 hole을 형성하여, 여기에 4종의 수복재를 충전하였다. 충전 직후부터 시작하여 24시간 경과시까지 일정 시간 간격으로 표면, 1mm,3mm깊이에서의 경도를 미세경도계(Shimadzu Micro Hardness Tester HMV-2000,Shimadzu Co.Japan)로 측정하였다. 측정치를 통계처리하여 얻은 결과는 다음과 같다. 1.4종의 수복재 모두에서,중합직후에 비해 24시간 경과후의 미세경도가 증가되었다. 2.중합 직후부터 24시간 경과후의 미세경도를 측정한 결과, Ketac-fil을 제외한 나머지 수복재에서는 각 깊이간 경도의 차이가 있었다. 3.각 수복재의 최종중합에 도달하는 시간을 조사한 결과, 이중중합형이 3mm의 깊이에서 광중합형이나 화중합형에 비해 중합이 더 오래 지속된 것으로 나타났다. 이상의 결과에서 조사광이 충분히 도달하지 못하여 중합이 현저히 떨어지는 수복재의 심부에도 이중중합방식을 사용할 경우에는 지속적인 중합반응이 일어나 중합도가 증가하는 것으로 나타났다. For the purpose of elucidating the polymerization modes of dual-cure restorative materials and comparing them with single-cure restorative materials,a study was performed on the light-cured composite resin,dual-cure composite resin,dual-cure glass innomer cement. By measuring the microhardness of each material at 0mm,1mm and 3mm depth during initial 24 hours with predetermined interval,the state of polymerization and degree of conversion was indirectly evaluated for each material,and obtained results are as follow: 1.All of four materials tested showed significant increase in microhardness after 24hrs compared with just after curing starts. 2.In all materials except Ketac-fil,there showed a significant difference in microhardness between each depth at each time interval. 3.In the test of lap time till final curing for each material,the polymerization process was revealed to last longer in the dual-cure type materials than in single-cure type materials at 3mm depth. Based on the results avobe,it was demonstrated with materials of dual-cure mode that the degree of conversion increase by successive curing reactions even in the deeper layers where sufficient curing light is impermeable.

감마선 조사 랫트의 고환에서 fibronectin의 발현

정진우,김희철,김정태,안미정,이지영,신태균 제주대학교 방사능이용연구소 2005 방사선응용과학연구소논문집 Vol.19 No.-

유리피판 이식술 83예의 분석

신극선,탁관철,윤정섭 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.1

Eighty-three consesutive free-flap transfers were reviewed to analyze distribution of type of reconsturctions, kinds of donor flaps as well incidence of complications. The role of emergent exploration and the effect of preoperative wound conditions in flap survival were evaluate. Free flap transfer for head and neck reconstruciton was most common as 46 cases, followed by for upper extremity of 22cases, for lower extremity 12 cases and for trunk & breast 3 cases. Two patients exhibited within 7 days after the operation because of respiratory complications. Eight flaps exhibited signs of circulatory insufficiency between 5 hours and 7 days. three were managed conservatively with ultimate partial necrosis of the flaps. Five flaps required return to the operating room. On exploration, early arterial occlusion was revealed in 1 flap, late arterial occlusion in 2 flaps, late venous occlusion in 1 flap and hematoma in 1 flap. The average time from the first abnormal examination to exploration was 2.4 hours. There were no false-positive explorations. Two free flaps in which abonormal findings were first noticed 4 days and 7 days after microsurgical transfer respectively failed in spite of the correction of the cause of circulatory compromise. The remaining 3 flaps were salvaged following the correction of the cause. Recipient vessel problems such as irradiation and infection were the most common cause of circulatory crisis. Among the five flaps requiring return to the operating room. single vein was anastomosed in four flaps and two veins in the remaining one. In the totally failed two flaps only songle vein was anastomosed. The results of this study demonstrate the efficacy of clinical monitoring and the role of early exploration. Precautious selection of recipient vessels and two vein anastomosis are recommended for safe and better prognosis.

한국판 신체변형장애 척도개발을 위한 예비연구

김정란,지익성,신석철 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.4

연구목적 : 본 연구의 목적은 신체변형장애의 진단 및 심한 정도를 평가하는 자기 보고형 검사인 한국판 신체변형 장애 척도(BDDE-SR)를 개발하고 한국 청소년내의 신체 불만족에 대한 자료를 얻고자 하는데 있었다. 방 법 : 한국판 BDDE-SR을 대전 시내 남녀 고등학생 417명을 대상으로 설문을 하였고. 이 중 100명을 선정하여 6주 간격후 재검사를 하였다. 결 과 : 1) 전체 점수에 대한 검사-재검사 신뢰도(Pearson 상관계수)는 0.883(p〈0.001)으로 만족할 만한 신뢰도를 보였으며, 각 문항에 대한 검사-재검사 신뢰도는 통계적으로 유의하였다(Spearman 상광계수 범위:0.159∼0.761). 2) 내적 일치도는 Cronbach's α0.922(p〈0.01)로 높은 신뢰도를 보였다. 3) Varimax 회전에 의한 요인 분석의 결과, 5개의 요인을 추출하였는데, 제1요인은 고통과 당황인자, 제2요인은 자기 의식 및 부정적 평가 인자, 제3요인은 회피인자, 제4요인은 가리기 인자, 그리고 제5요인은 비교 인자였다. 4) 한국 청소년의 신체 불판족에 대한 자료에서, 전체 점수는 여학생 집단에서 52.4±24.8로 남학생집단의 37.7±20.6보다 유의하게 높았다. 남녀 고등학생을 합하여 가장 만족하지 못하는 신체부위는 허리-배(6.8%), 코(6.4%), 다리전체(6.0%), 치아와 눈(각각 5.9%) 순이었다. 결 론 : 이 결과들은 한국판 BDDE-SR이 신체변형장애의 평가를 위한 신뢰할 만한 도구임을 입증하는 것이며, 향후의 연구들에서 신체변형장애 환자군을 대상으로한 임상 자료를 얻고 한국판 BDDE-SR의 타당도 검증이 시행되어야 할 것으로 생각된다. Objective : The purposes of this study were to develop a Korean version of the Body Dysmorphic Disorder Examination-Self Report(BDDE-SR) and to get informations about the body dissatisfaction of the Korean adolescents. Method : A Korean version of the BDDE-SR was applied to 417 Korean high school adolescents. Retest was conducted with 6-week interval in 100 adolescents. Results : 1) Test-retest reliability of the total scores(Pearson's correlation coeffciency) was 0.883(p〈0.001) and test-retest reliabilities of each item also showed high correlation (Spearman's correlation coefficency range : 0.159-0.761). 2) Internal consistency by Cronbach's alpha of 0.922(p〈0.001) was very much high. 3) Five factors were extracted by factor analysis with the Varimax rotation. They were 'the distressing and embarrassment factor','the self-consciousness and negative self-evaluation factor','the avoidance factor','the camouflage factor', and'the comparison factor'. 4) The total score of BDDE-SR of girls was statistically higher(52.4±24.8) than that of boys(37.7±20.6). The most dissatisfied body part was abdomen (6.8%), nose (6.4%), entire leg (6.0%), teeth (5.9%) and eyes (5.9%) in all the subjects. Conclusion : These results indicate that a Korean version of the BDDE-SR is a reliable instrument for the assessment of Body Dysmorphic Disorder (BDD). The authors suggest that future researches should be directed to obtaining clinical of the patients with BDD and should test the validity of a Korean version of the BDDE-SR.

분편 인플루엔자백신(split influenza vaccine)의 임상효과 및 면역원성에 관한 연구

우흥정,김동림,정희진,천병철,이주연,안정배,김지희,박찬,신영규,김우주,김민자,박승철 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

목적 : 아단위 인플루엔자 백신 접종 후 백신의 인플루엔자 예방효과, 인플루엔자 방어 항체형성, 인플루엔자 백신의 안전성을 조사하고자 하였다. 방법 : 총 571명을 대상으로 인플루엔자 백신 접종을 하였고, 이들 접종자에서 인플루엔자 양질환의 이환을 조사하여 인플루엔자 백신의 인플루엔자예방효과를 알아보았고, 백신의 접종 전 및 접종 4주 후 혈청에서 혈구응집억제물(Hemagglutination Inhibition : HAI) 항체 검사를 실시하여 백신의 방어항체생성을 조사하였고, 백신의 안전성을 알아보기 위해 백신접종 후 1주일 이내의 부작용을 조사하였다. 결과 :백신 접종군과 백신 비접종군에서 인플루엔자 양 질환의 이환을 조사한 결과 접종군 28.35%, 비접종군 35.88%으로 나왔으며, p 값이 0.001로 통계적으로 접종군에서 유의하게 낮았고, 인플루엔자 양 질환의 예방 효과는 20.97%를 보였다. 백신의 방어항체 형성의 평가를 위해 유럽의 인플루엔자 백신 허가 기준을 조사하였는데 B/Guangdong/5/94균주의 백신접종 후 항체가 40이상의 비율을 제외한 다른 기준은 모두 만족 시켰다. 부작용은 전체 조사자 521명중 149명(29%)으로 주로 접종 부위의 국소 부작용을 호소했고, 전신 부작용은 2% 내외였으며 특별히 심각한 부작용은 발견되지 않았다. 결론 : 분편 인플루엔자 백신은 인플루엔자양질환의 예방과 방어항체생성에 효과 있으며 안전한 것으로 사료된다. Background : The safety and effectiveness of influenza vaccine are well known in developed country. The influenza vaccination has been recommended as one of the tentative immunization schedule for indicated persons since 1997 in Korea. But there are still no available data about them, even though nearly 5 million doses of influenza vaccine were used in 1997-1998 season. So it is immediately needed to investigate the safety. efficacy and immunogenicity of influenza vaccine among Korean. Methods : We studied the clinical efficacy of influenza vaccine by monitoring Occurrence of influenza-like illness in influenza risk group(vaccination ; 300, non-vaccination; 215) from December in 1997 to March in 1998. We used the split quadrivalent influenza vaccine containing 15 microgram of hemagglutinin of A/Beijing/262/95(HlNl), A/Wuhan/359/95(H3N2), B/Mie/1/93 and B/Guangdong/5/94. Hemagglutination inhibition(HA1) antibody titers were determined before immunization and 1 months after vaccination And we evaluated adverse effect of influenza vaccination at 7 days after vaccination. Results : Influenza vaccination was associated with si@icant reductions in influenza-like spptoms(vaccination group; 28.35%, non-vaccination group, 35.88%, p=0.001). The preventive effect of influenza-like i3lne.s among influenza risk goup was 20.97%. And immunogenicity of influenza A and B exceeded all of the European licensure criteria for immunogenicity except postvaccination proportion of titers 240 of B/Guangdong/5/94 strain. And the adverse effects were mainly local injection site problem and no serious adverse effect was noted. Conclusion : Split influenza vaccine is safe, inmunogenic and eff'tive in influenza risk group in Korea.

한국인 성인에서 Fm θ의 출현 양상에 관한 연구

도정수,신석철,왕성근 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

The distinctive theta rhythm that appears at the frontal midline during the performance of mental tasks has been designated as frontal midline theta(Fmθ). Author tried to confirm the appearance pattern of Fmθ in Koean young adults, and investigated the relations among the appearance rates of Fmθ, sex, kinds of mental tasks, characteristics of personality trait, impulsiveness, temperament, and anxiety level. The subjects were 42 healthy male and female students(28 male, 14 female) aged 23 to 25(average age 23.9±0.6). The results were summarized as follows. 1. The individual variation of the appearance and appearance rates of Fmθ were large, and the appearance rates of Fmθ under Uchida-Kraepelin test were ranged 28.6~31.0%, and under reaction time were ranged 4.8%~21.4%. 2. The appearance rates of Fmθ tend to increase under continuous mental task than simlpe concentration. 3. There were no sexual difference in the apearance rate of Fmθ. 4. In the aspect of the anxiety level, the appearance rate of Fmθ seems to bo increased when the person's level of anxiety is low, the excitement strength is high, and less impulsive. 5. In the aspect of the personality, the appearance rate of Fmθ seems to be increased when the person's personality is introvert, the excitement strength is high, and the motility of temperament is high.

재발성 류마티즘 환자에서 발작의 유발인자

주유철,이동민,양종태,신병철,임태영,서정균,정기영,최동헌,김원,조영신,고희관 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : Palindromic rheumatism (PR) is known to be triggered without any obviously inciting events in most patients, although, in a few cases, attacks have been noted to relate to another events such as weather change, childbirth, ingestion of certain foods, or over-exercise. The aim of this study was to characterize the triggering factors on palindromic attacks. Materials and Methods : We evaluated sixty-four patients with PR for the presence of triggering factors and the relationship between attacks and triggering factors by interview of patients. We considered that there was an probable association between episodes and PR, if episodes within 24 hours prior to PR had triggered at least 50% of all attacks and a definite association between episodes and PR, if episodes within 24 hours prior to PR had triggered 100% of all attacks. Results : In 15 patients (35.9%), there was a possible association between episodes of PR and initiating events. In 8 patients (12.5%), there was a definite association between episodes of PR and initiating events. The triggering factors were physical over-activity including exercise (19/64: 29.7%), foods, such as rawfish, crab, and chicken, including alcohol (19/96: 19.8%). However, there were no difference between the groups with and without the triggering factor in sex ratio, duration and onset of PR, the positive rate of rheumatoid factor and involved sites. Conclusion : Our observations showed that PR was triggered by physical over-activity more than in previous reports and hypersensitivity to foods was a causative factor in some patients with PR. However, patients with triggering factors had a similiar clinical profile to patients without triggering factors.