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정상섭,박상근,오성훈,김선호,윤도흠,박정수,양우익,최인준,안영수,김경환,박창일,김진수,이현철 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.6
Recent experimental studies and clinical cases have suggested that grafting tissue from the adrenal medulla into the brain may alleviate the symptoms of Parkinson's disease. Autologous adrenal medullary grafts into the striatum was performed stereotactically in two patients with Parkinson's disease. Both patients were bedridden preoperatively, but 4 months after the surgery both became ambulatory and one was even capable of returning to his job. Even though the number of cases was small⑵ and the follow-up period was short, this study shows that adrenal medullary transplantation into the striatum may have some beneficial effects in patient with Parkinson's disease. Further experimental and clinical trials are necessary to see whether this procedure will be a recommendable surgical treatment for patients suffering from Parkinson's disease.
장항석<SUP>1<,SUP>,박준성<SUP>2<,SUP>,정웅윤<SUP>2<,SUP>,박정수<SUP>2<,SUP>,Hang-Seok Chang,M,D,<SUP>1<,SUP>,Jun Sung Park,M,D,<SUP>2<,SUP>,Woung Youn Chung,M,D,<SUP>2<,SUP> and Cheong Soo Park,<SUP> <,SUP>M,D,<S 대한갑상선-내분비외과학회 2001 The Koreran journal of Endocrine Surgery Vol.1 No.1
Bronchogenic cyst can be found about everywhere in the mediastinum and rarely in the abdomen. Embriologically, the bronchogenic cyst, one of the primitive foregut-derived developmental anomalies, is composed of any or all of the tissue elements seen in a bronchus including respiratory epithelium, smooth muscle, mixed serous and mucose glands and cartilage. Most bronchogenic cysts are asymptomatic. The diagnosis is therefore made either as an incidental finding or, more usually is secondary to other organic complications such as infection, hemorrhage, compression of adjacent organs. Only a few of subdiaphragmatic bronchogenic cyst have been reported and their occurrence in the retroperitonum is extremely rare. We present a case of retroperitoneal bronchogenic cyst presenting as adrenal tumor which was successfully treated by laparoscopic resection. (Korean J Endocrine Surg 2001;1:122-124)
김형일,홍순원<SUP>1<.SUP>,김은경<SUP>2<.SUP>,윤종호<SUP>3<.SUP>,박정수,Hyoung-Il Kim,M.D.,Soon Won Hong,M.D.<SUP>1<.SUP>,Eun Kyung Kim,M.D.<SUP>2<.SUP>,Jong Ho Yoon,M.D.<SUP>3<.SUP> and Cheong Soo Park,M.D. 대한갑상선-내분비외과학회 2004 The Koreran journal of Endocrine Surgery Vol.4 No.1
Adenolipoma of the thyroid gland, also called thyrolipoma, is an extremely rare neoplasm characterized by encapsulated or tumorous mass of admixtures of mature adipose tissue and thyroid tissue. Only a few scattered cases have been reported in English literatures. It should be differentiated with encapsulated papillary carcinoma, follicular neoplasm and liposarcoma. We report an additional case of an adenolipoma of the thyroid gland. (Korean J Endocrine Surg 2003;4:51-54)
The Treatment Choice for Patients with Papillary Thyroid Carcinoma
박정수(Cheong Soo Park),최진섭(Jin Sup Choi),박병우(Byeong Woo Park) 대한두경부종양학회 1993 대한두경부 종양학회지 Vol.9 No.2
유두상 갑상선암의 대부분은 서서히 진행하는 양호한 임상경과를 보이나, 일부는 저등급 혹은 미분화 갑상선암으로 전환되는 생물학적 특성을 보인다. 저자는 유두상 갑상선암 환자 358예를 적용된 치료방법과 치료결과를 분석하여 논란이 되고 있는 치료방법들 중에서 적절한 치료방법을 찾고자 본 연구를 시도하였다.% 568예중 동측엽절제술 및 협부 절제술 혹은 갑상선 아전 절제술 220예, 갑상선 전 절제술 혹은 근전절제술 143예, 종양적출술 5예였고, 이중 115예는 여러가지 형태의 경부 곽청술이 추가되었고, 150예는 수술후 방사성 동위원소 치료까지 추가되었다. 또 전 환자에서 TSH 억제를 위한 갑상선 호르몬 투여를 하였다. 추적 기간은 5년에서 12년까지 평균 8.5년이었다. Cady와 Rossia AMES Scoring system에 따라 저위험군과 고위험군으로 나누어 재발율과 사망율을 산출한 결과 저위험군 255예중 재발율 11.0%, 사망율 0.4%, 고위험군 65예중 재발율 36.9%, 사망율 20.0%을 보여 고위험군에서 현격히 불량한 예후를 나타내었다. 따라서 저자들은 유두상 갑상선암의 치료방법 선택은 일률적인 치료방법 보다는 환자 개인의 임상적 특성, 병기 등을 고려하여 저위험군에서는 소극적 수술을, 고위험군에서는 적극적인 수술과 수술후 보조치료를 시행하는 것이 바람직하다고 사료되었다.
Park, Subin,Park, Jong-Eun,Yoo, Hee Jeong,Kim, Jae-Won,Cho, Soo-Churl,Shin, Min-Sup,Cheong, Jae Hoon,Han, Doug Hyun,Kim, Bung-Nyun Wolters Kluwer Health | Lippincott Williams Wilkin 2015 PSYCHIATRIC GENETICS Vol.25 No.1
We examined the association between the selected polymorphisms in two candidate genes, the arsenite methyltransferase gene (AS3MT, rs11191454) and the inter-α-trypsin inhibitors heavy chain-3 gene (ITIH3, rs2535629), and attention-deficit hyperactivity disorder (ADHD) in a Korean population. A total of 238 patients with ADHD, along with both of their biological parents, were recruited. The children were administered intelligence quotient tests, whereas their parents completed the Child Behavior Checklist. In the transmission disequilibrium test on 181 trios, we found overtransmission of the A allele at the AS3MT rs11191454 polymorphism in children with ADHD (&khgr;=8.81, P=0.003). However, there was no preferential transmission at the ITIH3 rs52535629 polymorphism (&khgr;=0.14, P=0.707). Our results provide preliminary evidence for the overtransmission of the A allele at the AS3MT rs11191454 polymorphism in ADHD.
Environmental Tobacco Smoke Exposure and Children’s Intelligence at 8–11 Years of Age
Park, Subin,Cho, Soo-Churl,Hong, Yun-Chul,Kim, Jae-Won,Shin, Min-Sup,Yoo, Hee Jeong,Han, Doug Hyun,Cheong, Jae Hoon,Kim, Bung-Nyun NLM-Export 2014 Environmental health perspectives Vol.122 No.10
<P>Background: Evidence supporting a link between postnatal environmental tobacco smoke (ETS) exposure and cognitive problems among children is mounting, but inconsistent.</P><P>Objectives: We examined the relationship between ETS exposure, measured using urine cotinine, and IQ scores in Korean school-aged children.</P><P>Methods: The participants were 996 children 8–11 years of age recruited from five administrative regions in South Korea. We performed a cross-sectional analysis of urinary cotinine concentrations and IQ scores obtained using the abbreviated form of a Korean version of the Wechsler Intelligence Scales for Children. Associations were adjusted for potential confounders, and estimates were derived with and without adjustment for mother’s Full-Scale IQ (FSIQ) score.</P><P>Results: After adjusting for sociodemographic and developmental covariates, urinary cotinine concentrations were inversely associated with FSIQ, Verbal IQ (VIQ), Performance IQ (PIQ), vocabulary, math, and block design scores. Following further adjustment for maternal IQ, only the VIQ scores remained significantly associated with urinary cotinine concentration (B = –0.31; 95% CI: –0.60, –0.03 for a 1-unit increase in natural log-transformed urine cotinine concentration; <I>p</I> = 0.03).</P><P>Conclusion: Urine cotinine concentrations were inversely associated with children’s VIQ scores before and after adjusting for maternal IQ. Further prospective studies with serial measurements of cotinine are needed to confirm our findings.</P><P>Citation: Park S, Cho SC, Hong YC, Kim JW, Shin MS, Yoo HJ, Han DH, Cheong JH, Kim BN. 2014. Environmental tobacco smoke exposure and children’s intelligence at 8–11 years of age. Environ Health Perspect 122:1123–1128; http://dx.doi.org/10.1289/ehp.1307088</P>
Young Keun Cheong(鄭永根),Youn Sup Oh(吳潤燮),Young Il Lee(李榮日),Sun Young Choi(崔善英),Ki Hun Park(朴基勛),Moon Soo Park(朴文洙) 한국육종학회 1997 한국육종학회지 Vol.29 No.1
In order to obtain the basic information on the mutation breeding in peanut and to find out the efficient methods for the induction of mutation and selection criteria, the seeds of peanuts were subjected to mutagen treatment with the various levels of the γ-ray dosages (10, 20, 30 and 40kR) in the seeds contained different moisture. Emergence and survival rate of M₁ plants were decreased by the increase of dosage of gamma rays and the lethal dose (LD₅₀) was 30-40kR in the dried peanut seeds. The higher radiation dose level and moisture content in seeds lead to the more radiosensitivity in M₁ generation. The lethal dose (LD₅₀) of peanut seed with 10-25% moisture content was around 20kR. The order and spectra of chlorophyll deficient mutations were maculata, chlorotica, chlorina, albina and the total chlorophyll-deficiency rate was 14.8% at 30kR dose in the cotyledonary branch. The chlorophyll deficieny rate was negatively correlated with the main stem length and number of pods per plant in M₁ generation. The highly positive correlation coefficients between chlorophyll deficieny rate and morphological variant rate was observed in M₂ population