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Sort Sequences and Predictive Sorting Algorithms
Minyoung Yun 한국정보과학회 1997 Journal of Electrical Engineering and Information Vol.2 No.1
A sort sequence S_n is a sequence of all unordered pairs of indices in I_n= {1.2,....n}. With a sort sequence S_n we associate a predictive sorting algorithm A(S_n) to sort input set X= {X₁,X₂,...,X_n} as follows. An execution of the algorithm performs pairwise comparisons of elements in the input set X as defined by the son sequence, except that the comparisons whose outcomes can be inferred from the outcomes of the previous comparisons are not performed. The efficiency of a sorting algorithm is defined by the expected number of pairwise comparisons required. In this paper predictive sorting algorithms are obtained, based on known sorting algorithms, and are shown to be required on the average O(nlog n) comparisons.
Soluble form of ST6Gal is critical for radiation-induced migration of colon cancer cells
Minyoung Lee,Jung-Jin Park,Yeung Bae Jin,Yoon-Jin Lee,Young-Gyu Ko,Yun-Sil Lee 한국당과학회 2011 한국당과학회 학술대회 Vol.2011 No.1
The β-galactoside α 2,6-sialyltransferase (ST6Gal I) is an enzyme that adds sialic acids to N-linked oligosaccharides of glycoproteins. It is highly expressed in tumors, which probably the basis for the increase of α (2, 6)-sialylation found in cancer cells. Previously we found that ionizing radiation (IR) increased the expression of ST6Gal I, cleaved it into catalytically active form as comparable to enzyme localized in golgi, and these soluble forms were secreted into the culture media. Induction of ST6Gal I significantly increasedthe adhesion and migration of colon cancer cells via sialylation of integrin β1 that is mostlyrelated to cell adhesion and migration. In this study, we further investigated the function of ST6Gal I underlying cleavage, solubilization and release from the cells, especially focusing on the metastasis. ST6Gal I was cleaved by Alzheimer's beta-site amyloid precursor protein-cleaving enzyme (BACE), which was activated by IR, and besides golgi-localized ST6Gal I, soluble form of ST6Gal I was released into the culture media. Although soluble form of ST6Gal I also had sialylation activity, these forms enhanced the migration and invasion of colon cancer cells which was less dependent of intergrin b1 sialylation as compared with golgi-anchored form. Especially, we found that ST6 Gal I repress the E-cadherin promoter activity via induction of Snail. These data suggests that the glycoconjugation with unknown function of soluble sialyltransferase may involve in the process of cancer progression and metastasis which may be in cooperation with golgi-form.
윤민영 聖潔大學校 情報産業技術硏究所 1998 情報産業技術論叢 Vol.3 No.-
The Traveling Salesman Problem (TSP) is a well-known NP-Complete problem. In the TSP, the salesman would like to visit each city while minimizing the cost of traveling among all the cities. He only visits a city once and returning to where he began after visiting all the cities. A genetic algorithm is an adaptive search technique based on the principles and mechanisms of 'natural selection' and 'survival of the fittest' from the natural evolution. A genetic algorithm can effictively search the problem domain and easily solve complex problems. This paper proposes the application of the genetic algorithm to the Traveling Salesman Problem using the edge recombination method.
Minyoung Shin,Ahee Lee,A Young Cho,Minam Son,Yun-Hee Kim 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.8
Objective This study investigated the effects of process-based cognitive training that targets working memory and cognitive control on memory improvement in healthy elderly individuals and patients with mild cognitive impairment (MCI). Methods Forty healthy subjects and 40 patients with MCI were randomly assigned to either the intervention or control group. The intervention group received 12 sessions of designated cognitive training. The control group did not receive cognitive training. A memory test was administered pre-intervention, post-intervention, and 4 weeks after the intervention. Additional comprehensive neuropsychological tests were also administered including a depression scale questionnaire. Results Performance in attention and working memory, which are directly related to the training domains, and global cognitive function were improved in the intervention group after training. In memory tests, interference by irrelevant stimuli was reduced and recognition memory was improved after the intervention. Furthermore, cognitive training ameliorated depressive symptoms. These training effects were not dependent on MCI status. Conclusion Process-based cognitive training that targets working memory and cognitive control effectively improves memory processes including retrograde interference and recognition, as well as depressive symptoms associated with aging in healthy elderly individuals and patients with MCI. Psychiatry Investig 2020;17(8):751-761