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[PB-0071] GBS 분석을 통한 국내 무(Raphanus sativus L.) 품종의 유전적 유연관계 분석
Hui Yeon Hong(Hui Yeon Hong),Jun Ho Lee(Jun Ho Lee),Yoon Ah Jang(Yoon Ah Jang),Jin Hee Kim(Jin Hee Kim),Ji Won Kim(Ji Won Kim),Ji Hyeon Lim(Ji Hyeon Lim),Hye Won Yu(Hye Won Yu),Won Byoung Chae(Won Byo 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-
[PB-0073] 무(Raphanus sativus L.) 품종의 표현형적 특성과 heterozygosity 간의 상관관계 분석
Hui Yeon Hong(Hui Yeon Hong),Jun Ho Lee(Jun Ho Lee),Yoon Ah Jang(Yoon Ah Jang),Jin Hee Kim(Jin Hee Kim),Ji Won Kim(Ji Won Kim),Ji Hyeon Lim(Ji Hyeon Lim),Hye Won Yu(Hye Won Yu),Won Byoung Chae(Won Byo 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-
Social Network Characteristics and Body Mass Index in an Elderly Korean Population
Lee, Won Joon,Youm, Yoosik,Rhee, Yumie,Park, Yeong-Ran,Chu, Sang Hui,Kim, Hyeon Chang The Korean Society for Preventive Medicine 2013 Journal of Preventive Medicine and Public Health Vol.46 No.6
Objectives: Research has shown that obesity appears to spread through social ties. However, the association between other characteristics of social networks and obesity is unclear. This study aimed to identify the association between social network characteristics and body mass index (BMI, $kg/m^2$) in an elderly Korean population. Methods: This cross-sectional study analyzed data from 657 Koreans (273 men, 384 women) aged 60 years or older who participated in the Korean Social Life, Health, and Aging Project. Network size is a count of the number of friends. Density of communication network is the number of connections in the social network reported as a fraction of the total links possible in the personal (ego-centric) network. Average frequency of communication (or meeting) measures how often network members communicate (or meet) each other. The association of each social network measure with BMI was investigated by multiple linear regression analysis. Results: After adjusting for potential confounders, the men with lower density (<0.71) and higher network size (4-6) had the higher BMI (${\beta}$=1.089, p=0.037) compared to the men with higher density (>0.83) and lower size (1-2), but not in the women (p=0.393). The lowest tertile of communication frequency was associated with higher BMI in the women (${\beta}$=0.885, p=0.049), but not in the men (p=0.140). Conclusions: Our study suggests that social network structure (network size and density) and activation (communication frequency and meeting frequency) are associated with obesity among the elderly. There may also be gender differences in this association.
Change in Ischemia-Modified Albumin and Its Clinical Significance During Exercise Stress Testing
Lee, Dong-Hyeon,Jeon, Hui-Kyung,Park, Hun-Jun,Shin, Woo-Seung,Lee, Seung-Won,Youn, Ho-Joong,Kim, Chul-Min,Lee, Hae Kyung Japanese Circulation Society. 2010 CIRCULATION JOURNAL Vol.74 No.3
<P><B><I>Background:</I></B> There is little data about the additive effects of ischemia-modified albumin (IMA) on the exercise stress test (EST) used for the screening of ischemic heart disease. The relationship between myocardial ischemic burden and the change in IMA (ΔIMA) during EST was investigated. <B><I>Methods and Results:</I></B> EST was performed using the Bruce protocol to evaluate chest pain or exertional dyspnea in 155 patients (men 89, 53±13 years). Blood samples for IMA were obtained before and immediately after EST. According to the EST results and the pattern of ΔIMA, patients were categorized into 3 groups (none was classified as EST(-)/ΔIMA(+)): (1) (EST(-); (2) EST(+)/ΔIMA(-); and (3) EST(+)/ΔIMA(+). After EST, 60 of 155 (38.7%) patients were EST(+) and 14/60 (23.3%) were EST(+)/ΔIMA(+). Duke treadmill score was significantly lower in the EST(+)/ΔIMA(+) group compared with the other groups (-9.0±7.9, -1.7±4.2, 6.7±4.4, respectively, P<0.001); 43/60 (72%) patients with EST(+) underwent coronary angiography and the proportion of patients with a large ischemic burden was higher in the EST(+)/ΔIMA(+)group compared with the EST(+)/ΔIMA(-) group (72.7% vs 15.6%, P=0.001). <B><I>Conclusions:</I></B> Increased IMA after EST suggests a large ischemic burden in coronary artery disease, so the ΔIMA during EST may be useful for predicting the severity of myocardial ischemia. (<I>Circ J</I> 2010; <B>74:</B> 484 - 489)</P>
Lee, Hui-Young,Cho, Sun-A,Lee, In-Soo,Park, Jong-Hwan,Seok, Seung-Hyeok,Baek, Min-Won,Kim, Dong-Jae,Lee, Seok-Ho,Hur, Sook-Jin,Ban, Sang-Ja,Lee, Yoo-Kyoung,Han, Yang-Keum,Cho, Young-Keun,Park, Jae-Hak Oxford University Press 2007 FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY Vol.51 No.2
<P>The attenuation and immunoenhancing effects of rpoS and phoPSalmonella enterica serovar strain Typhi (Salmonella typhi) mutants have not been compared. Here, three S. typhi deletion mutants (phoP, rpoS, and rpoS-phoP double mutant) are constructed and these mutants are characterized with respect to invasiveness, virulence, and protective immune response compared with wild-type Ty2. It was found that phoP and phoP-rpoS deletion mutants are less invasive to HT-29 cells than the wild-type Ty2 and the rpoS single-deleted strain. The LD(50) of immunized mice was higher for phoP than for rpoS mutants, and the highest for the phoP-rpoS double mutant. In addition, all S. typhi mutants showed an increase in the specific serum IgG levels and T-cell-mediated immunity, and showed equal protection abilities against a wild-type Ty2 challenge after two rounds of immunization in BALB/c mice. It is concluded that phoP genes appear to play a more important role than rpoS genes in both cellular invasion and virulence of S. typhi, but not in immunogenicity in mice. Furthermore, the data indicate that the phoP-rpoS double mutant may show promise as a candidate for an attenuated typhoid vaccine.</P>
Lee, Hea-Yon,Kim, Jin-Jin,Ko, Eun-Sil,Kim, Sei-Won,Lee, Sang-Haak,Kang, Hyeon-Hui,Park, Chan-Kwon,Min, Ki-Ouk,Lee, Bae-Young,Moon, Hwa-Sik,Kang, Ji-Young The Korean Academy of Tuberculosis and Respiratory 2010 Tuberculosis and Respiratory Diseases Vol.69 No.4
We report the case of a 68-year-old man with a stromal tumor of uncertain malignant potential (STUMP), which had metastasized to the lung. The patient complained of an enlarged mass in the anterior chest. Chest computed tomography (CT) showed a sternal abscess with multiple nodules in both lungs. A thoracoscopic lung biopsy of the nodules and incision/drainage of the sternal mass were performed simultaneously. CT of the pelvis revealed an enlarged prostate with irregular cystic lesions in the pelvis. Prostate biopsy was done and demonstrated hypercellular stroma with minimal cytological atypia, a distinct pattern of STUMP. The sternal abscess proved to be tuberculosis and the lung lesion was consistent with STUMP, which had spread from the prostate. However, to our knowledge, the tuberculous abscess might not be assoicated with STUMP in the lung. The patient refused surgical prostatectomy and was discharged with anti-tuberculosis medication. On one-year follow up, the patient had no evidence of disease progression.
( Hui Seo Kim ),( Hae Won Kim ),( Sang Hee Lee ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Zinc deficiency can be cause by nutritional deficiencies, pregnancy, or absorption disorders such as Crohn`s disease or chronic disease patient. It presents immunodefi-ciency, in. ammation of eye, skin, or bowels. The patient was a 44-year-old male. He is bed-ridden status due to cervical spine injury. He has gastrostomy tube. He admitted ER with fever, ileus. There is no abnomal findings in labratory and radiologic test but eosinophilia, small bowel ileus, elevation of hs CRP and WBC. We suspected as a parasitic infection, especially Diphyllobothrium latum because we found Plerocerciod larvae in his feces. Patient has severe diarrhea so only transvenous nutrition was applied. And treated with albendazole. During the treatment, sudden blackish pigmented thick crusted patches on the dorsum of fingers and brown pigmentation on the distal part of fingers. Multiple erythematous papules on the face. Disseminated brownish macules with a few erythematous papules on both lower and upper extremities. Consult with dermatologist, zinc deficiency was suspected. Serum zinc level was checked and was much below than normal range. We applied oral zinc and after only 2 days skin lesion are improved.