여성 관상동맥질환자의 동기요인이 건강행위에 미치는 영향 요인

이혜영,정경옥,김금자 김천과학대학 2007 김천과학대학 논문집 Vol.33 No.-

Background: Misconceptions exist that coronary artery disease(CAD) is a male dominant disease, although the leading cause of death due to heart disease in women increased 7.1% from 2001 to 2004 in Korea. Lack of motivational factors to health behavior change places women at risk for subsequent CAD events. Purpose: The purpose of this study was to investigate motivational factors to health behaviors for women with coronary artery disease. Methods: Structured questionnaires survey was carried out on a convenience sample of 81 adult women in a cammunity setting. The subjects were recruited for an interview at outpatient clinic in hospitals. The data were analyzed using descriptive statistics, Pearson correlation coefficient and stepwise multiple regressions. Results; There were significant correlations between motivational factors and health behaviors(r=.664). Stepwise multiple regression revealed that 57% of variance in health behaviors was explained by self-efficacy and perceived benefits among four motivation variables(F=54.438 p<.01). However, there were no significant predicting factors of perceived barriers and emotional salience among motivational factors to health behaviors. Self-efficacy contributed the greatest amount of variance in health behaviors(β=.585), followed by perceived benefits(β=.226). Conclusions: The results of the study indicate that self-efficacy was very important in predicting health behaviors for women with coronary artery disease. Thus it would be necessary to include motivational factors in designing rehabilitation program to practice and adherence health behaviors for women with coronary artery disease.

지역별 보건소 이용의 만족도에 관한 연구 : 경북지역을 중심으로

이혜영,정경옥,김금자 김천과학대학 2007 김천과학대학 논문집 Vol.33 No.-

Purpose: The purpose of this study was to investigate the satisfaction and utilization and awareness of health center and satisfaction's affecting factors. Methods: The subjects consisted of 292 adult at three health centers on middle size cities in Gyeong San Buk-Do. Data was collected from August 2006 to June 2007 using structured questionnaires. One-way ANOVA were used to test satisfaction of health centers, utilization and awareness of health center and Kruskal-Wallis and Scheffe's test were used to test recommendation of health center and Post Hoc multiple comparison by using SPSS 14.0 for windows. Results: The satisfaction of health centers for community dwellers was related to age, educational level and family income and the difference of satisfaction of health centers were in comfortable surroundings, satisfaction of facilities, generosity of staff members and full explanation. The utilization and awareness of health center were differ from community areas. Conclusions: Further studies need to be done to investigate additional effects of satisfaction of health centers for community dwellers and to investigate nursing approaches for community dwellers to improve their satisfaction of health centers.

舞踊 專攻生의 體格과 體型에 關한 考察 : 忠淸南道 所在 中學校 學生을 中心으로

전혜자,우상연,이입주 순천향대학교 기초과학연구소 2004 순천향자연과학연구 논문집 Vol.10 No.2

The aim of this study is to ciassify, compare and analyze charecteristics of physiques and somatotypes of some middle school students majoring in Korean Dance(15 students), Modern Dance(15 students) and Ballet(14 students) in Chung nam Province. In order to get some results this study has used the methods to mesure the elements of physiques(Height, weight, girth of chest, sitting height, length of arms, length of legs) and to mesure skinfold thickness of four parts, bone diameters of two parts and muscle girth of two parts. The results of this study are as follows. 1. The mean height are 160.03±5.47(Modern dancers' group), sitting heights are 86.07±3.20(Modern dancers' group) But there is no significant differences. 2. The mean weights are 50.19±6.34(Korean danders' group), chest girth are 79.29±5.34(Korean cancers' group) But there is no significant differences. 3. The mean length of arms are 76.26±3.13(Ballet group), length of legs are 102.24±3.76(Ballet group) But there is no significant differences. 4. The rankings of muscle girth in two parts of obdies are 1) Modern dancers' group 2) Korean dancers' group 3) Ballter cancers' group and there are significant differences in maximum circumferencer of upper arms(p<0.05).

아마릴 정(글리메피리드 2㎎)에 대한 글리메드 정의 생물학적 동등성

조혜영,박은자,강현아,백승희,이석,김세미,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

The purpose of the present study was to evaluate the bioequivalence of two glimepiride tables, Amaryl^(?)(Handok/Aventis Pharm. Co., Ltd.) and Glimed (Kuhn Ⅱ Pharm. Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The glimepiride release from the two glimepiride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solution, water and blend of PSB 80 into each dissolution medium). Twenty six healthy male subjects, 22.65±2.19 years in age and 66.55±8.85 kg in body weight, were divided into two groups and randomized 2×2 cross-over study was employed. After one tablet containing 2 ㎎ as glimepiride was orally administered, blood was taken at predetermined time intervals and the concentrations of glimepiride in serum were determined using HPLC method with UV detctor. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC_(t), C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Amaryl were -3.70, -8.28 and 0.61% for AUC_(t), C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25)(e.g., log(0.84)∼log(1.04) and log(0.82)∼log(1.03) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guideline for the bioequivalence were satisfied, indicating Glimed tablet and Amaryl tablet were bioequivalent.

리스페달 정(리스페리돈 2㎎)에 대한 리스펜 정의 생물학적 동등성

조혜영,박은자,강현아,백승희,이석,박찬호,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

The purpose of the present study was to evaluate the bioequivalence of two risperidone tablets, Risperdal (Janssen Korea Co., Ltd) and Rispen (Myung In Pharm. Co., Ltd), according to the guidelines of Korea Food and Drug Administration (KFDA). The risperione release from the two risperidone formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with various of dissolution media (pH 1.2, 4.0, 6.8 butter solution and water). Twenty four healthy male subjects, 23.33±2.10 years in age and 69.24±8.05 kg in body weight, were divided into two groups and a randomized 2×2 crossover study was employed. After one tablet containing 2 ㎎ as risperidone was orally administered, blood was taken at predetermined time intervals and the concentration of risperidone in serum were determined using HPLC method with UV detector. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC_(t), C_(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t), C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Risperdal were 0.20, -1.29 and -11.09% for AUC_(t), C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.90)∼log(1.03) and log(0.84)∼log(1.09) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guideline for the bioequivalence were satisfied, indicating Rispen tablet and Risperdal tablet were bioequivalent.

비유피-4 정(염산프로피베린 20㎎)에 대한 건일염산프로피베린 정의 생물학적동등성

조혜영,박은자,강현아,백승희,김세미,박찬호,오인준,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.5

The purpose of the present study was to evaluate the bioequivalence of two propiverine hydrochloride tablets. BUP-4 (Jeil Pharm. Co., Ltd.) and Kuhnil Propiverine Hydrochloride (Kuhnil Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The propiverine release from the two propiverine hydrochloride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solutions, water and blend of polysorbate 80 into pH 6.8). Twenty six healthy male subjects, 23.73 ± 2.79 years in age and 67.04 ± 7.93 kg in body weight, were divided into two groups and a randomized 2 x 2 cross-over study was employed. After one tablet containing 20 mg as propiverine hydrochloride was orally administered, blood was taken at predetermined time intervals and the concentrations of propiverine in serum were determined using HPLC method with UV detector. The dis-solution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC" C _(max) and T _(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC, C_(max), and untransformed T_(max). The results showed that the differences between two formulations based on the BUP-4 were 0.17%, 7.98% and 4.55% for AUC,, C_(max), and respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically trans-formed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.88)-log(l .12) and log(0.90)-log(l.15) for AUC, and _(max), respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Kuhnil Propiverine Hydrochloride tablet was bioequivalent to BUP-4 tablet.

스프렌딜 지속정(펠로디핀 5㎎)에 대한 스타핀 지속정의 생물학적동등성

조혜영,강현아,이석,백승희,박은자,최후균,문재동,이용복 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.4

Felodipine is a calcium antagonist that lowers blood pressure by reducing peripheral resistance by means of a direct, selective action on smooth muscle in arterial resistance vessels. Furthermore, it have been approved for the effective in angina pectoris and cardiac failure. The purpose of the present study was to evaluate the bioequivalence of two felodipine extended release (ER) tablets, Splendil (YuHan Corporation) and Stapin (Hana Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). THe felodipine release from the two felodipine formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method at pH 6.5 buffer solution. Twenty six healthy male subjects, 22.73±1.78 years in age and 66.66±7.28 ㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After two tablets containing 5 ㎎ as felodipine were orally administered, blood sample was taken at predetermined time intervals and the concentrations of felodipine in serum were determined using column-switching HPLC method with UV detector. The dissolution profiles of two formulations were similar at pH 6.5 buffer solution. Besides, the pharmacokinetic parameters such as AUG_(t), C_(max) and T_(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t) and C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Splendil were 2.53%, 1.32% and 18.32% for AUC_(t), C_(max) and T_(mzx), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.86)∼log(1.20) and long(0.89)∼long(1.23) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guidelines for the bioequivalence was satisfied, indicating Stapin ER tablet and Splendil ER tablet are bioequivalent.

중·고등학생들의 본드남용 실태조사

윤운상,홍관이,노성규,백혜자,주왕기 江原大學校附設體力硏究所 1980 江原大學校附設體育科學硏究所論文集 Vol.- No.5

In the light of recent evidence that the abuse of inhalants is increasing among the Korean youth. A comprehensive inhalants use questionnaire was administered to a sample of 790 Kangweon provincial high school(junior and senior) seniors to determine whether or not a similar trend was evident among this students. Results indicated that 13.2% of the respondents report having tried inhalants in their lifetime, and daily use was reported by 4% among users. Somewhat higher propotions of males(15.9%) than females(10.4%), and TAT※※ high school students(17.2%) than academic high school students(12.6%) are involved in inhalants use. Inhalants users, markedly are more involved in other drugs use and they are dis-satisfied with self and their living environments. 74.0 percent of the students used inhalants for the curiosity.

Deceased donor liver transplantation under the Korean model for end-stage liver disease score-based liver allocation system: 2-year allocation results at a high-volume transplantation center

Hea-Seon Ha,Jung-Ja Hong,In Ok Kim, M.Sc.,Sae-Rom Lee,Ah-Young Lee,Tae-Yong Ha,Gi Won Song,Dong-Hwan Jung,Gil-Chun Park,Chul-Soo Ahn,Deok-Bog Moon,Ki Hun Kim,Sung Gyu Lee,Shin Hwang 대한이식학회 2019 Korean Journal of Transplantation Vol.33 No.4

Background: The Korean model for end-stage liver disease (MELD) score-based liver allocation system was started in June 2016 in Korea. Methods: This study analyzed the detailed allocation results of deceased donor liver transplantation (DDLT) during the first 2 years after the MELD score-based liver allocation system implementation at a high-volume liver transplantation (LT) center in Korea. Results: This study included 174 patients with age above 12 years. The patient ABO blood groups were A (n=65, 37.4%), B (n=51, 29.3%), O (n=28, 16.1%), and AB (n=30, 17.2%). The LT types were primary LT in 141 patients (81.0%) and retransplantation in 33 (19.0%). The Korean Network for Organ Sharing status categories at LT were as follows: status 1 (n=11, 6.3%), status 2 (n=82, 47.1%), status 3 (n=63, 36.2%), and status 4 (n=18, 10.3%). The mean MELD score at LT and waiting period were 36.6±4.6 and 62.1±98.2 days in blood group A; 37.6±3.6 and 25.7±38.1 days in blood group B; 38.8±2.7 and 26.0±30.5 days in blood group O; and 34.8±5.5 and 68.4±110.5 days in blood group AB (P<0.001 and P=0.012), respectively. Patients with blood group O and AB had the highest and lowest mean MELD scores at LT allocation, respectively. Conclusions: Serious deceased organ donor shortage resulted in very high MELD score cutoffs for DDLT allocation. Additionally, a significant inequality was observed in the possibility for DDLT according to blood group compatibility. Nationwide follow-up studies are necessary to precisely determine the allocation status of DDLT.

타이치 운동 중재 후 균형 증진에 관한 논문분석

이혜영(Lee Hea-Young),서문자(Suh Moon-Ja),이은옥(Lee Eun-Ok),은영(Eun Young),최정현(Choi Jung Hyun) 한국성인간호학회 2004 성인간호학회지 Vol.16 No.3