임신마우스에서 수용성카이토산에 의한 태아의 방사성스트론튬 오염 억제

채기문,최근희,양광희,범희승,김지열,김광윤 대한방사선 방어학회 1994 방사선방어학회지 Vol.19 No.3

핵분열생성물중의 하나인 방사성스트론튬은 임신한 쥐에서 태반을 빠르게 통과하여 태아를 오염시킨다. 독성이 적은 천연착화제로서 마우스체내의 방사성스트론튬(Sr-85)의 제거에 효과적인 것으로 알려진 카이토산을 이용하여 Sr-85의 태반오염억제에 관한 연구를 하였다. 실험군은 일반식이를 공급한 대조군과 임신 17일째에 수용성카이토산을 피하(1% 카이토산), 구강(10% 카이토산), 복강(0.3% 카이토산)으로 주사한 카이토산군으로 분류하였다. 피하주사군은 Sr-85 오염후 카이토산을 주사한 군이며 복강과 구강주사군은 Sr-85 오염젼 15일간 카이토산을 공급한 군이었다. 출산과 동시에 어린마우스의 전신을 측정한 겨러과 출생후 7일째에 대조군이 2.8 ±0.3%의 전신축적율을 나타낸 반면 피하, 구강, 복강, 주사군은 각각 1.2 ±0.1%, 1.4 ±0.1%, 1.6 ±0.2%로 나타났다. 결과적으로 임신한 마우스에서 수용성카이토산은 방사성스트론튬의 태반오염을 유의하게 억제하는 것으로 사료된다. Radiostrontium passes the placental barrier in pregnant rodents very well. Chitosan, a natural nontoxic chelator, was reported to reduce whole body retention of radiostrontium in mice. The aim of the present study was to evaluate water soluble chitosan as a blocking agent of transplacental transfer of radiostrontium in pregnant mice. Twenty pregnant mice wre divided into four groups : control and three groups of chitosan treatment(groups 1 to 3). Sr-85(15KBq in 0.2ml saline) was subcutaneously injected into pregnant mice at the 17th day of pregnancy. In control mice, 0.2ml saline was given 5 hours after the injection of Sr-85. In group 1.1% water soluble chitosan was given subcutanously for two days, twice daily after the injection of Sr-85. In group 2, 10% water soluble chitosan was given orally for 15 days before conception. In group 3, 0.3% water soluble chitosan was injected intravenously for 15 days, once daily before conception. Gamma counting of newborns were done at days 0, 2 and 7 after their births. Whole body retention of Sr-85 in newborns of control mice at days 0, 2, 7 were 3.1 ±0.3%, 2.9 ±0.3%, 2.8 ±0.3% respectively. In experimental groups, whole body retention of Sr-85 was significantly lower thanthat of control(p<0.01) and no statistical difference was noted between them. In group 1, the values were 2.1 ±0.3%, 1.4 ±0.1%, 1.4 ±0.1%, respectively. In group 3, they were 2.1 ± 0.2%, 1.7 ± 0.2%, 1.6 ± 0.2%, respectively. In conclusion, the water soluble chitosan reduced transplacental contamination of radiostrontium in pregnant mice.

카이토산을 이용한 방사성스트론튬 오염의 치료

김지열,송호천,양광희,최근희,채기문,범희승,김광윤 대한방사선 방어학회 1994 방사선방어학회지 Vol.19 No.3

본 연구에서는 마우스에 이미 오염된 방사성스트론튬(Sr-85)을 제거하는데 수용성카이토산이 어느정도 효과가 있는지 알아보고자 하였다. Sr-85를 정맥주사한 경우 주사후 1일째의 체내 잔류량은 72.9 ±5.7%, 5일째는 57.7 ±1.9%, 7일째는 54.2 ±1.4%로 서서히 감소하였으며, Sr-85를 복강내 주사한 경우는 주사후 5일째 54.4 ±1.2%, 15일째 50.6 ±0.8%로 정맥주사에 비해 낮은 잔류량을 보였다(5일째 잔류량의 비교, P<0.05), 0.3% 수용성카이토산을 1회 정맥주사해준 제21군 및 10% 수용성카이토산을 식이중에 섞어 먹인 제5군은 각각의 대조군에 비해 체내 잔류방사능의 차이가 없었으나 (P>0.05), 0.3% 수용성카이토산을 3일간 정맥주사한 제3군과 3% 수용성카이토산을 이틀 간격으로 15일간 복강내 주사한 제6군에서는 각각의 대조군에 비해 낮은 잔류방사능을 보였다. (P<0.01). 결론적으로 수용성카이토산을 연속적으로 정맥투여하거나 복강내 투여하는 경우에는 스트론튬의 골대사촉진 또는 골중의 스트론튬과의 반응등을 통해 그 배출을 촉진시킬 것으로 사료되었다. The aim of the present study was to elucidate the effect of the water soluble chitosans on the removal of contaminated radiostrontium(Sr-85) from the bone of mice. The remaining radioactivities in intravenously injected controls(group 1) were higher than in intraperitoneally injected controls (group 4, P<0.01). The % retention at day 5 were 57.7 ±1.9%, 54.4 ±1.2%, respectively. Single intravenous injection of 0.3% water soluble chitosan and continuous oral ingestion of 10% water soluble chitosan for 15 days were ineffective on the removal of contaminated radiostrontiums. Multiple intravenous or intraperitoneal injections of water soluble chitosan effectively removed contaminated radiostrontiums (P<0.01 vs controls). In conclusion, water soluble chitosan might remove once incorporated radiostrontium from bones of mice. further studies were needed to elucidate the mechanism of the removal.

중력자료 분석에 의한 전라남도 순천시 첨산 일원의 지하구조 해석

최광선,박명희 부산대학교 사범대학 과학교육연구소 1996 科學敎育硏究報 Vol.23 No.-

사춘기전 치주염 치료시 공제영상 측정법 이용에 대한 증례보고

최신규,이광희 大韓小兒齒科學會 1993 大韓小兒齒科學會誌 Vol.20 No.2

Subtraction technique has increased detectability of small osseous changes compared with conventional radiograph. We used subtraction technique in analysis and evaluation of the bone density change before and after the treatment of prepubertal periodontitis in an eleven-year-old female patient. The patient was examined clinically, hematologically and radiologically. Clinical examination showed periodontal abscess in maxillary right second premolar and first molar area and gingival swelling in maxillary left premolar area. The result of hematological analysis was within normal limit. Radiological examination showed vertical bone resorption at maxillary right first premolar and first molar and also periapical lesion at maxillary right premolar. The patient was treated by subgingival curettage, endodontic treatment and reconstructive osseous surgery. Hydroxyapatite was filled in mesial and distal area of maxillary right first premolar and mesial area of maxillary first molar. In radiographic view at 6 months after operation, normal bony trabecular pattern was observed in the defect area which was embedded by HA. Apical lesion disappeared and lamina dura has a normal pattern. Daily mechanical removal of plaque by patient was emphasized for the success of treatment. This study revealed that the subtraction technique increased the accuracy of radiograph reading in the treatment of periodontitis.

서울 지역 사무직 근로자의 음주에 관한 행태 및 관련요인에 관한 조사 연구

최승희,김명,김광기 韓國保健敎育.健康增進學會 2001 보건교육건강증진학회지 Vol.18 No.2

In this study, I investigate the drinking behavior and related factors among white collar workers in seoul. Examination was executed with questionnaire to 520 white collar workers. Drinking behavior involves frequency of drinking, amount of alcohol consumption in a drinking situation and alcohol-related problem. Related factors involves the goneral characteristics, the knowledge about alcohol, the allowable attitude about drinking, work stress and stress copying. This was analyzed with percentage, mean, standard deviation, t-test, ANOVA and pearson's correlation. The results are as follows : Data shows that about 96.3% of the respondents drink at least during the last year and 89.8% of the respondents drink at least during the last month.59.4% male respondents drink 3∼8 times a month, 44.8% female respondents drink 1∼2 times a month. High prevalence rates were found in male, married person and those with low-religious spirit in a usual amount of drinking(p<0.05), male in the latest amount of drinking(p<0.05), male, forties, married person and those with the highest monthly family income and those with low-religious spirit in frequency of drinking during the latest month(p<0.05). The score of alcohol-related problem(ARP) was as follows : male workers-2.61, female workers-1.61 out of 35. The score of ARP was statistically significantly different according to sex(p<0.05). A positive correlation was observed between amount of drinking, frequency of drinking and ARP(p<0.01). The score of knowledge about alcohol was 3.6 and any correlation and statistically significant difference were not observed between the knowledge about alcohol and drinking behavior. The score of allowable attitude about drinking was statistically significantly different according to sex(p<0.05), age(p<0.05). A positive correlation was observed between attitude about drinking and amount of drinking, frequency of drinking, ARP(p<0.01). The work stress and stress copying had no significant relations with drinking behavior Most respondents do not drink at stress situation.

소수성 촉매를 이용한 수소동위원소 교환 반응 측정을 위한 순환 반응기

최희주,이한수,안도희,강희석,김광락 한국공업화학회 2002 응용화학 Vol.6 No.2

The catalytic rate constants of hydrophobic catalysts developed for the removal of tritium mainly generated in the pressurized heavy water reactors should be measured. A recycle reactor was designed and built for characterzing the long-term behavior of the catalyst performance at the various temperatures and gas velocities.The catalytic rate constants were measured at the apparent gas velocity of 0.5 m/s and the temperature of 60℃. The initial catalytic constant was 8.44×10^-4mol/g.sec. This value is much greater than that considered in the design of Wolsong Tritium Removal Facility.

姙娠婦의 體型 變化에 따른 원피스 드레스의 基本 原型 硏究

崔光希,咸玉相 啓明大學校 生活科學硏究所 1994 科學論集 Vol.20 No.-

The purpose of this study was to investigate the actual conditions of wearing and make the basic style of one - piece dress which is suitable for the peculiarity of the body shape and this investigation was done on the questionnaires. And then, I studied the peculiarity of the pregnant wome's body shape by the measurement for the 161 women who were 3 months - 10 months pregnant. The comparison between the existing dress style and the new one acquired by research through the test on wearing was followed by making a one - piece dress style that was based on things as above. The conclusions drawn are as follows : 1. As the results, pregnant women prefered one - piece dress style and they had 2-4 maternity robes. The time that they wore maternity robes was from the middle of their pregnancy period(5 months - 7 months) in which the changes of their body shape were notable. It came out that the requisites for the maternity robes are to have the merits of being convenient in activity and the merits of being convenient in activity and the suitability. 2. Compared with the state of 3 month - pregnancy, the results of the measurement through the pregnancy period showed that there was notable increase in the bust, waist, omphalos and the abdomen when they were 10 months pregnant. According to the cross - index and sliding gauge, there was just a little change in the bust and hip, but the abdomen showed lots of changes as pregnancy advanced. Consequently, when the pregnancy advanced to 10 months, the shape of the abdomen was changed to the round one. 3. In the design of one - piece dress, according to the style - design and the research of it, there was notable increase in the waist and the abdomen. So, in the design of the one - piece dress style, extra pieces of clothes were given 0.8cm to the side lines front and back and the center of the front part for 4 - month - pregnancy 1.5cm for 5 - month - pregnancy. To solve the problem that the length of the front part of the dress went shorter than that of the back part on account of the advance of pregnancy, 0.5cm was given to the front edge for 5 - month - pregnancy, 1.5cm for 7 - month - pregnancy, and 2.5cm for 9 - month - pregnancy. 4. According to the tests on the appearance of the dress style, the level of α<0.01 was showed difference significantly in the 15 items out of 17 ones and α<0.05 in the extra pieces of clothes around the hip and the place of the vertical center line in the back. In the test items, the general average score of the exiting style was 3.01 and the new one researched is 3.91. So the latter excelled the former. Also in the test on the function, this new one, in which th peculiarity of body shape and the extra pieces of clothes were taken into consideration, exelled in all the 5 movements on the level of α< 0.01. These results of the overall tests as above show that the new style excels the existing on in the suitability for the body.

韓牛改良을 爲한 屠體特性에 關한 硏究

尹熙燮,李基萬,吳世正,崔炳奎,李廣田 건국대학교 1974 學術誌 Vol.17 No.1

Carcasses from thirty (male : 12, female: 18) Korean Cattle were used to study the yield of meat cuts by the conventional cutting method as well as the American method. The dressing percents and correlation cofficients among meat cuts in a carcass were also investigated. The regression equations for predicting the total carcass lean from meat cuts is of particular importance in studies of carcass evaluation. Physical separation of the entire carcass is laborious and costly. Therefore, a simple indirect method for predicting total carcass lean would be extremely useful. The regression equations of total carcass lean on certain meat cuts were calculated in this study. Dressing percents from male and female carcasses were 49.64%, 48.37% respectively. Comparing the dressing percents of Korean cattle with idealized beef cattle, the percents from Korean cattle were much below those from beef. The percents of round, chuck, and shortloin from Korean cattle were also lower than those of beef cattle. Correlation coeffidient between carcass and lean weight was highly significant. Correlation coefficients among meat cuts were highly associcted with carcass weight. Therefore, the results of this study indicate that using the regression equations is possible for predicting total lean from certain meat cuts.

폐쇄성 수면무호흡증 진단을 위한 두부규격 방사선사진 계측 분석에 의한 한국 성인 정상교합자의 정상치에 관한 연구

박광호,김경호,최희수,허종기,배진성 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.1

Purpose : The lateral cephalometric Korean norms of the skeletal and pharyngeal dimension were analyzed for the diagnosis of obstructive sleep apnea syndrome(OSAS). Materials and Methods : The lateral cephalometric radiographies were taken in male(n=53) and female(n=50), who had a normal profile, class I occlusion, normal ANB (0∼4˚) and normal Wits Appraisal(-4∼0mm). The X-rays were traced by two oral and maxillofacial surgeons twice. The significant differences between male-female and examiners were tested. Results : The angle of mandibular line to Nasion-Sella line was 31.12˚/33.79˚(in male/in female, p=0.0018). The lower Gonion angle was 73.74˚/73.74˚(p=0.9978). The length of the soft palate was 36.93mm/34.35mm(p=0.0002). The pharyngeal airway space was 13.42mm/11.55mm at mandibular plane level(PAS(ML))(p=0.0025). The hyoid was placed inferiorly to mandibular plane 10.18mm/7.72mm(p=0.0051). The results from this study are to be used for the diagnosis of OSAS.

한국인에서 혈소판 당단백 Ⅲa 유전자 다형성과 급성 관동맥 증후군의 관계

김광일,채인호,김효수,손대원,오병희,이명묵,박영배,최윤식,이영우 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.5