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Ku, Jeonghun,Lee, Jang Han,Han, Kiwan,Kim, Sun I.,Kang, Youn Joo,Park, Eun Sook Wolters Kluwer Health, Inc. All rights reserved. 2009 AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITA Vol.88 No.9
Ku J, Lee JH, Han K, Kim SI, Kang YJ, Park ES: Validity and reliability of cognitive assessment using virtual environment technology in patients with stroke. OBJECTIVES:: We assessed the validity and reliability of a virtual environment technology (VET)-based cognitive assessment program that was developed as a measurement tool of cognitive abilities in patients after a stroke. DESIGN:: Twenty participants diagnosed with stroke caused by unilateral brain lesions were enrolled to assess the VET program’s validity and test-retest reliability. Participants underwent evaluation by paper-based neuropsychological tests including the Korean Mini-Mental Status Examination, the Korean-Wechsler Adult Intelligence Scale, the Motor Free Visual Perception Test, Rey-Kim Memory Test, and Kim’s Frontal-Executive Neuropsychologic Test as well as the VET-based cognitive assessment. Major variables and indices of the VET program were calculated. The VET program validity was evaluated using a simple correlation analysis between variables from the VET program and conventional paper-based neuropsychological measurements, and the reliability was evaluated by investigating the test-retest correlation coefficients. RESULTS:: Major variables and indices of the VET program in patients with stroke correlated significantly with the related scores of paper-based neuropsychological tests. In addition, the test-retest reliability analysis revealed that the correlation coefficients ranged from 0.528 to 0.926. CONCLUSION:: The VET-based cognitive assessment program showed adequate reliability and validity as a method of cognitive assessment in patients after stroke.
Kim, Jeonghun,Koh, Jong Kwan,Kim, Byeonggwan,Ahn, Sung Hoon,Ahn, Hyungju,Ryu, Du Yeol,Kim, Jong Hak,Kim, Eunkyoung WILEY‐VCH Verlag 2011 Advanced Functional Materials Vol.21 No.24
<P>An iodine‐free solid‐state dye‐sensitized solar cell (ssDSSC) with 6.8% efficiency can be fabricated using conductive polymers and organized mesoporous TiO<SUB>2</SUB>. On page 4633, Eunkyoung Kim, Jong Hak Kim, and co‐workers show the effects of polymer conductivity and transmittance of the interfacial TiO<SUB>2</SUB> layer on energy conversion efficiency. This method can be used for the fabrication of various photovoltaic cells. </P>
KIM, SANGMIN,KIL, WON HO,LEE, JEONGMIN,OH, SOO-JIN,HAN, JEONGHUN,JEON, MYEONGJIN,JUNG, TAEWOO,LEE, SE KYUNG,BAE, SOO YOUN,LEE, HYUN CHUL,LEE, JUN HO,YI, HA WOO,KIM, SEOK WON,NAM, SEOK JIN,LEE, JEONG E Spandidos Publications 2014 ONCOLOGY REPORTS Vol.32 No.6
<P>Expression of the CD44 gene is upregulated in breast cancer cells and is correlated with patient survival. Aberrant CD44 expression promotes tumor progression and metastasis. In the present study, we investigated the role of zerumbone (ZER) on regulatory mechanisms of CD44 expression in breast cancer cells. Our results showed that CD44 expression was significantly increased by epidermal growth factor receptor (EGFR) ligands in SKBR3 breast cancer cells. In contrast, EGF-induced CD44 expression was decreased by a MEK1/2 inhibitor, UO126, or STAT3 inhibitor, STAT3 VI, respectively. Notably, ZER downregulated the basal level of CD44 expression in CD44+ breast cancer cells. In addition, the induction of CD44 expression by EGFR ligands, EGF or TGF-α, was markedly decreased by ZER treatment. Finally, we investigated the inhibitory mechanism of ZER on EGF-induced CD44 expression. Our results showed that EGF-induced phosphorylation of STAT3 was completely suppressed by ZER. Collectively, ZER suppressed EGF-induced CD44 expression through inhibition of the STAT3 pathway. Therefore, we suggested that ZER may act as a promising therapeutic drug for the treatment of breast cancer.</P>
Camouflaged Adversarial Attack on Object Detector
Jeonghun Kim,Kyungmin Lee,Hyeongkeun Lee,Hunmin Yang,Se-Yoon Oh 제어로봇시스템학회 2021 제어로봇시스템학회 국제학술대회 논문집 Vol.2021 No.10
The existence of physical-world adversarial examples such as adversarial patches proves the vulnerability of real-world deep learning systems. Therefore, it is essential to develop efficient adversarial attack algorithms to identify potential risks and build a robust system. The patch-based physical adversarial attack has shown its effectiveness in attacking neural network-based object detectors. However, the generated patches are quite perceptible for humans, violating the fundamental assumption of adversarial examples. In this work, we present task-specific loss functions that can generate imperceptible adversarial patches based on camouflaged patterns. First, we propose a constrained optimization method with two camouflage assessment metrics to quantify camouflage performance. Then, we show the regularization with those metrics can help generate the adversarial patches based on camouflage patterns. Furthermore, we validate our methods with various experiments and show that we can generate natural-style camouflaged adversarial patches with comparable attack performance.
Kim, Cheolwoo,Lee, Jusuk,Cho, Jeonghun,Oh, Yeonock,Choi, Yoon Kyung,Choi, Eunjeong,Park, Jaiwook,Kim, Mahn-Joo American Chemical Society 2013 Journal of organic chemistry Vol.78 No.6
<P>Forty-four different secondary alcohols, which can be classified into several types (II-IX), were tested as the substrates of ionic surfactant-coated <I>Burkholderia cepacia</I> lipase (ISCBCL) to see its substrate scope and enantioselectivity in kinetic and dynamic kinetic resolution (KR and DKR). They include 6 boron-containing alcohols, 24 chiral propargyl alcohols, and 14 diarylmethanols. The results from the studies on KR indicate that ISCBCL accepted most of them with high enantioselectivity at ambient temperature and with useful to high enantioselectivity at elevated temperatures. In particular, ISCBCL displayed high enantioselectivity toward sterically demanding secondary alcohols (types VIII and IX) which have two bulky substituents at the hydroxymethine center. DKR reactions were performed by the combination of ISCBCL with a ruthenium-based racemization catalyst at 25–60 °C. Forty-one secondary alcohols were tested for DKR. About half of them were transformed into their acetates of high enantiopurity (>90% ee) with good yields (>80%). It is concluded that ISCBCL appears to be a superb enzyme for the KR and DKR of secondary alcohols.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/joceah/2013/joceah.2013.78.issue-6/jo3027627/production/images/medium/jo-2012-027627_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/jo3027627'>ACS Electronic Supporting Info</A></P>
Kim Jeonghun,Chun Sang Hun,Amornkitbamrung Lunjakorn,Song Chanyoung,육지수,Ahn So Yeon,Kim Byung Woo,임용택,OH,BYUNG-KEUN,엄숭호 나노기술연구협의회 2020 Nano Convergence Vol.7 No.6
Gold particles have been widely used in the treatment of prostate cancer due to their unique optical properties, such as their light-heat conversion in response to near-infrared radiation. Due to well-defined synthesis mechanisms and simple manufacturing methods, gold particles have been fabricated in various sizes and shapes. However, the low photothermal transduction efficiency in their present form is a major obstacle to practical and therapeutic uses of these particles. In the current work, we present a silica-coated gold nanoparticle cluster to address the therapeutic limit of single gold nanoparticles (AuNPs) and use its photothermal effect for treatment against PC-3, a typical prostate cancer. Due to its specific nanostructure, this gold nanocluster showed three times higher photothermal transduction efficiency than free single AuNPs. Moreover, while free single particles easily clump and lose optical properties, this silica-coated cluster form remained stable for a longer time in a given medium. In photothermal tests under near-infrared radiation, the excellent therapeutic efficacy of gold nanoclusters, referred to as AuNC@SiO 2 , was observed in a preclinical sample. Only the samples with both injected nanoclusters followed by photothermal treatment showed completely degraded tumors after 15 days. Due to the unique intrinsic biocompatibility and higher therapeutic effect of these silica-coated gold nanoclusters, they may contribute to enhancement of therapeutic efficacy against prostate cancer.
The v2.0+EDR Bluetooth SOC architecture for multimedia
Kim, Jeonghun,Choi, Youngwhan,Jeong, Jungwon,Lee, Suhho,Kim, Suki IEEE 2006 IEEE TRANSACTIONS ON CONSUMER ELECTRONICS - Vol.52 No.2
This paper presents a Bluetooth system on chip (SOC) architecture for multimedia applications. The SOC includes all necessary baseband-parts, RF-parts, a sub-band codec (SBC) and an application processor to achieve a Bluetooth specification v2.0+EDR (enhanced data rate). Dual bus architecture is selected to improve data transmission efficiency between a baseband and a system bus. The receiver uses an optimized low-IF (1.5 MHz) architecture which is trade-off between power and performance on CMOS technology. The transmitter uses a direct up conversion architecture. This chip occupies a die size of 28 mm<SUP>2</SUP> in a 0.18 μm CMOS. This chip and a flash memory are put into multi chip package (MCP). The maximum current consumption of the total chip is 65 mA at the TX mode. The internal supply voltages of RF- and digital-parts are 1.8 V. First measurement results meet most of the Bluetooth specification v2.Q+EDR and show the suitability of the presented single-chip concept.
Waterborne polyacrylic/PEDOT nanocomposites for conductive transparent adhesives.
Kim, Byeonggwan,Park, Teahoon,Kim, Jeonghun,Kim, Eunkyoung American Scientific Publishers 2013 Journal of Nanoscience and Nanotechnology Vol.13 No.11
<P>A new nanocomposite for conductive transparent adhesives (CTAs) was synthesized by emulsion polymerization of acrylate monomers dispersed with poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS). Polymer particles of waterborne CTAs were uniform, and the average size of the particles was 330 nm. The conductive transparent adhesive nanocomposites (CTANs) were casted onto various substrates including slide glass, indium tin oxide (ITO) glass, and PET film. Upon thermal processing at 80 degrees C, highly transparent adhesive films were obtained with surface uniformity. The stress of the CTANs was affected by the contents of PEDOT:PSS, and a 7.5 wt% CTAN film had the highest maximum stress of 0.33 MPa. Importantly, polyacrylic nanoparticles were well dispersed with conductive filler PEDOT:PSS in water because of their high dispersity in water. Therefore, the polyacrylic/PEDOT nanocomposite had a low percolation threshold of approximately 8% due to the enhanced connection between conductive channels. The CTANs with an optimum content (10 wt%) of PEDOT:PSS had high electromagnetic interference shielding effectiveness (36 dB) and transparency (75%) for application to electronics including displays and solar cells.</P>